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Taste masking pharmaceutical excipients and their applications
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Xiang-an-ni KONG1, Lei ZHAO2, Wen-zhen ZHAN1, Yu-xuan LI1, Chang LI3, Jia-sheng TU1, *, Chun-meng SUN1, *
Acta Pharmaceutica Sinica | 2023, 58(11) : 3179 - 3184
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Acta Pharmaceutica Sinica | 2023, 58(11): 3179-3184
• Special Reports: Pharmaceutical Taste-Masking and Assessment Technologies •
Taste masking pharmaceutical excipients and their applications
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Xiang-an-ni KONG1, Lei ZHAO2, Wen-zhen ZHAN1, Yu-xuan LI1, Chang LI3, Jia-sheng TU1, *, Chun-meng SUN1, *
Affiliations
  • 1. NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nangjing 210009, China
  • 2. Center for Drug Evaluation, National Medical Products Administration, Beijing 100022, China
  • 3. Department of Pharmaceutics, School of Pharmacy, Tianjin Medical University, Tianjin 300041, China
Published: 2023-11-12 doi: 10.16438/j.0513-4870.2023-1015
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The taste of drugs has an important impact on the compliance of patients, but most of the active drug ingredients have an uncomfortable taste, especially traditional Chinese medicine. Through a variety of pharmaceutical excipients with taste masking properties combined with corresponding technologies can improve the taste of drugs and the characteristics of other dosage forms, so as to improve patient compliance. Here, we mainly summarize the auxiliary materials used for taste masking, explain the mechanism of taste masking from the point of view of excipients and introduces related uses, so as to provide reference for further research on taste masking of pediatric preparations.

pharmaceutical excipient  /  taste masking  /  pediatric medicine  /  application
Xiang-an-ni KONG, Lei ZHAO, Wen-zhen ZHAN, Yu-xuan LI, Chang LI, Jia-sheng TU, Chun-meng SUN. Taste masking pharmaceutical excipients and their applications[J]. Acta Pharmaceutica Sinica, 2023 , 58 (11) : 3179 -3184 . DOI: 10.16438/j.0513-4870.2023-1015
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Article Info
doi: 10.16438/j.0513-4870.2023-1015
  • Receive Date：2023-08-31
  • Online Date：2025-11-21
  • Published：2023-11-12
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History
  • Received：2023-08-31
  • Revised：2023-10-30
Affiliations
    1. NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nangjing 210009, China
    2. Center for Drug Evaluation, National Medical Products Administration, Beijing 100022, China
    3. Department of Pharmaceutics, School of Pharmacy, Tianjin Medical University, Tianjin 300041, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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