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Recent advances of pharmaceutical 3D printing extrusion molding technology
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Ke ZHANG1, Dao-yi ZHENG1, An-ran LI2, Si-yuan LIU1, Zhi-jun WANG2, Yu CHEN2, Jia-li YU1, Yuan GAO2, Jian-jun ZHANG1, *
Acta Pharmaceutica Sinica | 2023, 58(9) : 2640 - 2655
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Acta Pharmaceutica Sinica | 2023, 58(9): 2640-2655
Recent advances of pharmaceutical 3D printing extrusion molding technology
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Ke ZHANG1, Dao-yi ZHENG1, An-ran LI2, Si-yuan LIU1, Zhi-jun WANG2, Yu CHEN2, Jia-li YU1, Yuan GAO2, Jian-jun ZHANG1, *
Affiliations
  • 1. School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
  • 2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China
Published: 2023-09-12 doi: 10.16438/j.0513-4870.2023-0112
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3D printing is an additive manufacturing technology with the help of digital control. Since FDA approved the first 3D printing drug in 2015, its research enthusiasm in the pharmaceutical field has been increasing year by year. In printing technology, fused deposition molding (FDM) and semi-solid extrusion (SSE) are the two most widely used extrusion molding technologies. In this review, recent advances of pharmaceutical 3D printing extrusion molding technology are reviewed from six aspects: mechanism, equipment, pharmaceutical excipients, applications, design and industrialization prospects of extrusion molding technology.

3D printing  /  fused deposition molding technology  /  semi-solid extrusion technology  /  equipment principle  /  pharmaceutical excipient
Ke ZHANG, Dao-yi ZHENG, An-ran LI, Si-yuan LIU, Zhi-jun WANG, Yu CHEN, Jia-li YU, Yuan GAO, Jian-jun ZHANG. Recent advances of pharmaceutical 3D printing extrusion molding technology[J]. Acta Pharmaceutica Sinica, 2023 , 58 (9) : 2640 -2655 . DOI: 10.16438/j.0513-4870.2023-0112
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Article Info
doi: 10.16438/j.0513-4870.2023-0112
  • Receive Date：2023-02-06
  • Online Date：2025-11-21
  • Published：2023-09-12
Article Data
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History
  • Received：2023-02-06
  • Revised：2023-05-08
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Affiliations
    1. School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
    2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China
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