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Research progress of traditional Chinese antidepressant herb-pair
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Shi-wei ZHU1, 2, Xiao-xia GAO1, Jun-sheng TIAN1, Xue-mei QIN1, Guan-hua DU1, 3, Yu-zhi ZHOU1, *
Acta Pharmaceutica Sinica | 2019, 54(2) : 235 - 244
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Acta Pharmaceutica Sinica | 2019, 54(2): 235-244
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Research progress of traditional Chinese antidepressant herb-pair
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Shi-wei ZHU1, 2, Xiao-xia GAO1, Jun-sheng TIAN1, Xue-mei QIN1, Guan-hua DU1, 3, Yu-zhi ZHOU1, *
Affiliations
  • 1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
  • 2. College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
  • 3. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2019-02-12 doi: 10.16438/j.0513-4870.2018-0825
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Depression, a global disease with various pathogenic factors, is seriously affecting human physical and mental health. In Chinese traditional medical theory, the disease belongs to the category of "Yu Zheng". At present, on the one hand, adverse reactions to antidepressant western medicine are becoming more and more prominent. On the other hand, the study of their antidepressant active ingredients and compatibility mechanisms has become a difficult field in the traditional Chinese medicine compounds due to their complexity. The Chinese antidepressant herb-pairs has become a hot topic in the field of antidepressant research. Herb-pair is the core of traditional Chinese medicine compound. In addition, the compound itself is a herb-pair. The study of traditional Chinese antidepressant herb-pairs is more conducive to clarify the compatibility mechanism of herb interaction and the mechanism of antidepressants on the body.Therefore, this paper systematically expounds antidepressant herb-pairs from the study of material, pharmacokinetics and efficacy, which aims at providing theoretical support for the compatibility mechanism of antidepressant herb-pairs and the research of new antidepressant drugs.

antidepressant  /  traditional Chinese medicine  /  herb-pair  /  compatibility mechanism  /  depression model  /  pharmacokinetics
Shi-wei ZHU, Xiao-xia GAO, Jun-sheng TIAN, Xue-mei QIN, Guan-hua DU, Yu-zhi ZHOU. Research progress of traditional Chinese antidepressant herb-pair[J]. Acta Pharmaceutica Sinica, 2019 , 54 (2) : 235 -244 . DOI: 10.16438/j.0513-4870.2018-0825
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Article Info
doi: 10.16438/j.0513-4870.2018-0825
  • Receive Date：2018-09-08
  • Online Date：2026-01-26
  • Published：2019-02-12
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History
  • Received：2018-09-08
  • Revised：2018-10-18
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Affiliations
    1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
    2. College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
    3. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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