Full
Outline
To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) guided biopsy in the differential diagnosis of benign and malignant liver lesions.
A total of 160 patients with suspected liver cancer admitted to Qinzhou First People's Hospital from December 2022 to December 2023 were retrospectively selected, and all of them received conventional ultrasound-guided and CEUS-guided puncture biopsy after admission, and the detection, diagnostic efficacy and contrast-enhanced ultrasound indexes of benign and malignant lesions were analyzed with the results of pathological examination as the gold standard.
Among the 160 patients with suspected liver cancer, 95 were malignant and 65 were benign confirmed by surgery and pathology. CEUS-guided biopsy detected 84 cases of malignant and 60 cases of benign, with a positive rate of 88.42% (84/95). The sensitivity, specificity and accuracy of CEUS-guided biopsy were 88.42%, 92.31% and 90.00%, respectively, which were significantly higher than those of conventional ultrasound-guided biopsy (69.47%, 75.38% and 71.86%, respectively), while the missed diagnosis rate and misdiagnosis rate of CEUS-guided biopsy were 11.58% and 7.69%, respectively, which were significantly lower than those of conventional ultrasound-guided biopsy (30.53% and 24.62%, respectively), with statistically significant differences (all P<0.05). The regional blood flow (rBF) and perfusion index of malignant lesions in arterial phase were higher than those of benign lesions (P<0.05), and the rBF in delayed phase was lower than that of benign lesions (P<0.05). The initial peak time, peak time, rise time and transit time of contrast agent were shorter than those of benign lesions (P<0.05).
For the differential diagnosis of benign and malignant liver lesions, CEUS-guided biopsy has higher sensitivity, specificity and accuracy than conventional ultrasound. It can observe the blood perfusion characteristics of liver lesions and effectively distinguish between benign and malignant liver diseases.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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