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  • Si-Li Zhang, Shi-Min Deng, Yue-Hua Bai, Rui-Qi Li
    Laboratory Testing. 2024, 2(1): 63-67.

    Food re-inspection refers to food production and operation of food safety supervision and sampling inspection conclusions have objections and in accordance with the law to the market supervision and management department to submit an application for re-inspection, market supervision and management department commissioned the re-inspection of the re-inspection of the backup samples for review and inspection of the behaviour.Re-inspection is an important way for food producers and operators to safeguard their legitimate rights and interests, an important link for market supervision departments to ensure the high quality of food safety supervision work, and an important measure to ensure the relatively fair and stable operation of the market. Because the retest conclusion serves as the final conclusion Therefore, the professionalism of the re-inspection institution is particularly important in the re-inspection work. Based on the perspective of the re-inspection institution, this paper analyzes the risk points of the food re-inspection acceptance work (i. e., contract review), so that the re-inspection institution can avoid potential risks and lay a solid foundation for the smooth progress of the whole re-inspection work.

  • Ling-Ling HUANG, Jia-Jun YAN, Jun-Ye YANG
    Laboratory Testing. 2024, 2(1): 1-4.

    Objective To establish an analytical method for the rapid determination of mold and yeast in dried rice noodles based on matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Methods GB 4789.15-2016 "National Food Safety Standard Food Microbiological Inspection Mold and Yeast Enumeration" was used to detect and analyze the molds and yeasts of dried rice flour in the laboratory from 2021 to 2022, and 10 wild strains were obtained, and identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Results According to statistics, the dried rice noodles sampled by the laboratory from 2021 to 2022 are contaminated by fungi. of which the total detection rate of mold and yeast is about 45.45%. Through MALDI-TOF MS identification, among the 10 wild strains, mold accounts for 80% and yeast accounts for 20%. Conclusion MALDI-TOF MS, as a rapid, sensitive, accurate and high-throughput microbial identification technology, has realized the rapid and specific identification of mold yeast in dried rice noodles, and can provide scientific basis for the detection of mold yeast in dried rice noodles.

  • Xiao-Hong DENG, Guo-Wei ZHONG, Yin YAN
    Laboratory Testing. 2024, 2(1): 107-111.

    Food inspection and testing institutions need to obtain corresponding qualification recognition in order to provide verifiable data results to society. Familiarity with the CMA qualification recognition and review process is a condition for the normal operation of food inspection and testing institutions. This article is based on the requirements outlined in RB/T214-2017, RB/T215-2017, and related norms and testing standards. Using the example of the on-site assessment of the CMA qualification extension for the food testing laboratory at the Zhenjiang Food and Drug Supervision Inspection Center, this article conducts an analysis of non-conformities and proposes targeted improvements. Additionally, it summarizes some experiences and reflections in areas such as personnel, instrumentation, system documentation, environmental facilities, and method validation. These insights are intended to serve as a reference for relevant personnel and laboratories in their pursuit of normal operations and conducting CMA qualification assessment reviews.

  • Yu-Xin SHI, Jia-Xing GUAN, Bo-Hua ZOU, Xia-Yang WANG, Le QIN
    Laboratory Testing. 2024, 2(1): 101-106.

    In order to solve the problems of significant increase in workload, cumbersome management work, duplication of materials and low review efficiency caused by the increase of open subject application year-by-year, this article elaborates and analyzes the various needs in the open project management process, based on the requirements of the project-oriented management system, and the laboratory open subject management system was constructed based on the requirements of subject management system. The system is developed based on SpringBoot microservice architecture, B/S(Browser/Server) architecture, and Java language development. It can complete project demand reporting, requirements review, requirements selection, project application collection, project application review, project project initiation, mid-term inspection results management, and final inspection, and realize the information management of the whole life cycle of laboratory open projects.

  • Dai-Xiao YANG, Jian SHEN, Zhi-Feng ZHANG, Xu-Xia LIANG, Xiao-Yan Liang
    Laboratory Testing. 2024, 2(1): 129-135.

    Objective Based on gas chromatography-mass spectrometry (GC-MS) technology and partial least squares analysis (PLS-DA) metabolomics methods, observe the changes in serum metabolites of mice after administration of traditional Chinese medicine Yuanbaocao, and provide a preliminary explanation for the analgesic mechanism. Methods Establish two analgesic models, the hot plate method and the acetic acid writhing method, and use GC/MS to detect and analyze etabolites in mouse serum. After collecting data, PLS-DA method is used to detect and classify endogenous small molecule metabolites in the samples. Results The hot plate analgesic experiment showed that there were extremely significant differences $\left({P<{0.01}}\right)$ in the licking time between the aspirin group, the high and medium dose groups of Yuanbaocao mice, and the model group at 30 and 60 minutes. As the administration time prolonged, Yuanbaocao showed different inhibitory effects on pain symptoms, which was inferred to be related to the high or low blood drug concentration. Compared with the blank group, the number of body twists in the Yuanbaocao group mice decreased significantly $\left({P <{0.01}}\right)$ , indicating that Yuanbaocao has a certain degree of analgesic effect. There are significant differences in the metabolic characteristics of mouse serum, and further screening of metabolic pathways that have a significant impact on data classification identified that taurine, glutathione, arginine and proline, ascorbic acid 5 metabolic pathways are related to pain metabolism. Conclusion The Yuanbaocao group can reverse abnormal changes to a certain extent and has analgesic effects.

  • Zhao-Lan ZHU, Hao-Nan JIN, Ming-Yue ZHANG
    Laboratory Testing. 2024, 2(2): 84-87.

    ABSTRACT: Inspection file management is an important component of laboratory management work, and its management level directly affects the efficiency of laboratory work and the accuracy of inspection results. The information management archive management method can not only replace paper archive management, but also provide real-time, Objective, and accurate monitoring data. This paper analyzed the background and current situation of archives management in inspection and testing laboratories, and put forward countermeasures, construction contents and value embodiment of electronic archives management, so as to provide effective reference for the archives management of inspection and testing laboratories, meet the requirements of drug inspection and drug technical supervision, and make archives management more in line with the requirements of the times.

  • Feng ZUO, La-Hong BIAN, Rui LI, Gai-Di LI, Gao-Quan MI, Fan KUANG
    Laboratory Testing. 2024, 2(1): 35-41.

    Objective To investigate the levels of veterinary drug residues in chicken and eggs in chicken production bases in Liangshan Prefecture, and evaluate the dietary exposure risk. Methods There were 353 samples of chicken and eggs collected from 17 cities in Liangshan in 2022, then the residues of quinolones and quinoline were detected and analyzed by liquid chromatography-mass spectrometry, and the exposure risk was assessed by point estimate method. Results A total of 221 pieces of chicken were sampled in 2022, among 8 types of veterinary drugs were tested with the detection rate of 25.79%, and the unqualified rate was 1.81%. Among 132 eggs, only enrofloxacin residue was detected, the detection rate was 1.52%, the unqualified rate was 1.52%. The point estimate method was used to assess the dietary risk of veterinary drug residues, and its hazard quotient was lower than 1, indicating that the veterinary drug residues have a lower risk to human health. Conclusion Veterinary drug residues can be detected in some samples of chicken and eggs in Liangshan in 2022, and the risk residues to human health is low, but the health risks of caused by some undetectable veterinary drugs cannot be ignored.

  • Yi-Fan ZHANG, Yu ZHANG
    Laboratory Testing. 2024, 2(1): 68-72.

    With the outbreak of the novel coronavirus in 2020, the demand and production of medical masks have shown a spurt of growth worldwide. In order to ensure the quality and safety of masks, countries around the world generally formulate testing standards for medical masks. This paper mainly compares and analyzes the detection standards of medical masks at home and abroad, and puts forward suggestions for the quality assurance and standard formulation of medical masks in China, which is of great significance to the field of public health.

  • Yong-Chao LIU, Xin TANG, Xiao-Cen LI, Xiao-Chen SUN, Li-Li ZHAO
    Laboratory Testing. 2024, 2(2): 70-73.

    Food safety issues not only involve the vital interests of the masses, but also related to the harmony and stability of the society and the long-term peace and stability of the whole country, the food industry is duty-bound responsibility and obligation to do a good job in food inspection and testing and control the quality of food. Food safety inspection and testing is a key link to ensure food safety. The authority of food safety inspection and testing institutions depends on its scientific and efficient technical management and service system, the establishment of food safety inspection and testing sharing platform, and the application of a series of new generation information technologies such as big data, cloud computing, and the Internet of Things to food safety control. Make full use of and optimize the allocation of these social resources, and integrate advanced management concepts to promote the standardization of food safety laboratory management processes, which can effectively improve the efficiency and quality of testing work, give full play to the technical support and guarantee role of food testing for food safety, and strengthen the ability of the whole society to prevent and control food safety risks.

  • Wei ZHU, Zhi-Xiang CHENG, Xin-Yuan FU
    Laboratory Testing. 2024, 2(2): 114-118.

    ABSTRACT: In the setting of escalating international trade, distinct variances emerge in the prerequisites for the quality and safety benchmarks of modified starch across different countries and regions. Taking distarch phosphate as an example, this article compares and analyzes the similarities and differences in relevant standard technical indicators and testing Methods between China and major trading regions or countries such as JECFA, the European Union, the United States, Japan, and South Korea, providing technical support for the international trade of modified starch.