Objective To understand the water quality of a remote rural well in a northern city, and to provide rationalized recommendations for the targeted development of a water quality improvement program. Methods The water quality of 32 self-provided wells in the area was sampled during the abundant and dry water periods each year from 2021 to 2023, tested and evaluated in accordance with the Sanitary Standard for Drinking Water (GB/T 5750-2006) and the Hygiene Standards (GB 5749-2006) for testing and evaluation use SPSS 26.0. Results Show that the 192 water samples tested, 144 are qualified, the pass rate is 75.00%. Dry water period pass rate is 84.38%. Abundant water period pass rate is 65.63%. Conclusion The water quality pass rate of a remote rural well in a northern city is lower than the pass rate in the dry season, and the water quality needs to be improved to ensure the safety of drinking water and the health of rural residents.

Objective To optimize the detection ability of Staphylococcus aureus in our laboratory by participating in the verification of the detection ability of Staphylococcus aureus in cosmetics organized by the Test and Evaluation Center of Chinese Academy of Inspection and Quarantine. Methods The samples were tested according to the test instructions of ACAS-PT1637 (2023) for the detection ability of Staphylococcus aureus in cosmetics and the Technical Specification for Cosmetic Safety (2015 edition). At the same time, the conventional biochemical detection methods, ATB bacteria identification and fluorescence quantitative PCR amplification were used to detect. Results Staphylococcus aureus was not detected in sample 23-Q777 and Staphylococcus aureus was detected in sample 23-A973. The result of this ability verification is satisfactory. Conclusion By participating in this capability verification, the laboratory not only improved the detection ability of the bacteria, but also effectively demonstrated that the laboratory has the ability to detect Staphylococcus aureus in cosmetics by using a variety of methods.

In current technological research and laboratory testing, quality management is crucial to ensuring the reliability of test data, the accuracy of test results, and the repeatability of tests. In order to improve the quality management level of testing laboratories, various quality management system certifications such as CNAS (China National Accreditation Service for Conformity Assessment) and CMA (China Inspection Body and Laboratory Mandatory Approval) have been widely used in laboratories through certification and review processes. The laboratory extensively employs the PDCA cycle (Plan-Do-Check-Act) in quality management. This article explores the application of the PDCA cycle in quality management of testing laboratories and its benefits to laboratory quality management.

Objective To study, discuss and analyze the reasons for deviations in drug test results and find out methods for quality control. Methods 150 drug samples from October 2022 to October 2023 were randomly collected and tested using two methods: UV spectrophotometry and high performance liquid chromatography. The results of the drug samples tested by the two methods were comparatively analyzed. Find out the reasons for deviations in drug test results, and finally conduct further research based on the situation of the drugs to find ways to control drug quality. Results The deviation rate of the drug detected by UV spectrophotometry was 4%, and the deviation rate of the test results obtained by high-performance liquid chromatography was 3.33%. The difference between the groups was not statistically significant (P>0.05). The two methods were used to detect the deviation rate. The deviation rate of drug test results is different, but the difference is not significant. Conclusion There are many factors that cause deviations in drug testing results. To ensure that drug testing results have high accuracy, scientific and reasonable testing methods and technologies must be used to ensure the standardization of operations during testing and reduce the impact of variable factors on The influence of test results can reduce errors, improve the accuracy of test results, maximize the efficacy of drugs, and ensure the quality of drugs.

With the increasing frequency of scientific research activities in universities, laboratory gas cylinders have both special equipment and hazardous chemicals, making their safe use and management particularly important. This article first analyzes the main problems in the current management of gas cylinders in university laboratories, and then proposes improvement measures from the perspective of gas cylinder users to strengthen safety education and training for gas cylinder users, develop and improve operating procedures for gas cylinder use, and standardize the safety inspection of gas cylinders; propose to audit supplier qualifications from the perspective of managers and standardize source management; carry out graded and classified supervision, and implement a regular inspection system; using information technology to improve management efficiency; intensify the promotion of safety culture and establish a management strategy for benchmark laboratories, aiming to improve the safety of laboratory gas cylinder use and provide reference for laboratory gas cylinder safety management.

In university laboratories, physics thinking dominated by science and technology is in a dominant position. Usually, university laboratory managers summarize the causes of accidents and carry out safety education or inspection according to the conclusions. This kind of summary management method is essentially based on physical thinking, and its main disadvantage is that it can not cover all the hidden dangers, and accidents will continue to happen. Biological thinking comes from biological system, and its characteristics of co-existence with risk are highly compatible with laboratory safety management. By applying biological thinking to laboratory safety management, this paper gives full play to the advantages of biological thinking to solve laboratory safety problems, and carries out safety education by using biological thinking, in order to enhance the safety awareness of teachers and students, expand the scope of hidden danger prevention, and provide unified thinking methods for some specific operations in current management.

Objective To explore the comprehensive quality evaluation of Panax notoginseng based on high performance liquid chromatography (HPLC) multi-component quantification combined with grey relational analysis. Methods HPLC was used to simultaneously determine the contents of notoginsenoside R1, ginsenoside Rg1, Re, Rb1, and Rd in Panax notoginseng samples from different origins and different commercial specifications. A comprehensive quality evaluation model was established by combining the grey relational method. Results The established method simultaneously determined the contents of notoginsenoside R1, ginsenoside Rg1, Re, Rb1, and Rd, with good methodological investigation results. The grey relational method could distinguish between samples from authentic origins, qualified samples, and unqualified samples. Conclusion The fusion model of HPLC multi-component quantification and grey relational analysis was constructed to accurately evaluate the quality of Panax notoginseng, providing a scientific evaluation basis.

Engineering rubber products are widely used in construction, transportation, industry, and other fields, and their quality is directly related to the safety and longevity of projects. Therefore, establishing scientific testing standards and quality control techniques is crucial. This paper first introduces the basic characteristics of engineering rubber products and their main application areas, followed by a discussion on the standardized testing process, including physical property testing, chemical composition analysis, and performance evaluation. In terms of quality control techniques, the paper details the control methods during production, the selection and testing of raw materials, and the key stages of finished product inspection. Finally, with reference to current technological advances, the paper looks ahead to the future development trends of testing and quality control technologies for engineering rubber products, particularly focusing on intelligent testing and the use of environmentally friendly materials. This study is of great significance for improving the performance of engineering rubber products, extending their service life, and ensuring project safety, while also providing theoretical and technical support for the formulation of testing standards and quality control specifications in relevant industries.

Objective Establish a detection methodology that can quickly, easily, and in large quantities analyze and detect the blood concentration of valproic acid, and can be applied to evaluate the bioequivalence of Sodium Valproate Sustained-Release Tablets in healthy volunteers. Methods Organize subjects to take the test and reference formulations of 0.5 g sodium valproate sustained-release tablets, collect blood samples, and prepare plasma samples. Determine the concentration of valproic acid in plasma using the established ultra performance lc-mass spectrometry/mass spectrometry (UPLC-MS/MS). Results Under fasting and postprandial conditions, both formulations were bioequivalence in terms of absorption rate and degree. Conclusion This experiment established an accurate and rapid UPLC-MS/MS method for detecting the content of valproic acid in human plasma samples. Two formulations have bioequivalence.

Objective The microwave digestion procedure was not clearly described in the previous standard, which affected the systematic analysis of measurement factors. Methods The heavy metals in municipal sludge was determined by the microwave high-pressure digestion-ICP. A mathematical model for heavy metals measurement in the municipal sludge was established. Results The main sources of uncertainty come from ICP instrument, sample weighing and calibration curve fitting. Conclusion Countermeasures and suggestions for reducing the uncertainty were introduced, which may provided technical basis for improving the accuracy of heavy metals measurement.