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Outline
To investigate the ameliorative effect of B-3 probiotic powder on diet-induced obesity in rats.
First, the obesity model was established by feeding rats with high-calorie diet and the rats were divided into a blank control group, a model control group and low, medium and high-dose B-3 probiotic powder groups. The rats were continuously administered for 42 d. The body weight and food intake data were recorded weekly. At the end of the experiment, the levels of perirenal fat, peritesticular fat, serum inflammatory factors,adiponectin and intestinal hormones were measured.
B-3 probiotic powder significantly inhibited body weight gain, perirenal fat, peritesticular fat, body fat weight, fat/body ratio and food utilization rate increase in obese rats. Serum analysis indicated that oral administration of B-3 probiotic powder significantly reduced the levels of interleukin-6 and C-type reactive protein and increased the levels of adiponectin (P<0.01), glucagon-like peptide-1 and peptide YY in the serum of obesity model rats.
B-3 probiotic powder can effectively inhibit diet-induced obesity in rats by promoting the secretion of glucagon-like peptide-1 and peptide YY and by promoting the secretion of adiponectin to inhibit obesity-induced inflammatory response.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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