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Research progress on oxidation preparation methods and biological activity of theaflavins
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Zhi-Yuan WANG1, Ya-Fei ZHAO1, Ze-Ping WU1, Xiao-Qiang CHEN1, Xiao-Lei LU2, *
Journal of Food Safety & Quality | 2025, 16(3) : 83 - 93
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Journal of Food Safety & Quality | 2025, 16(3): 83-93
Special Topic: Functional Foods and Functional Components
Research progress on oxidation preparation methods and biological activity of theaflavins
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Zhi-Yuan WANG1, Ya-Fei ZHAO1, Ze-Ping WU1, Xiao-Qiang CHEN1, Xiao-Lei LU2, *
Affiliations
  • 1. School of Life and Health Sciences, Hubei University of Technology, Wuhan 430068, China
  • 2. Hangzhou Tea Research Institute, CHINA COOP, Hangzhou 310016, China
Published: 2025-02-15 doi: 10.19812/j.cnki.jfsq11-5956/ts.20241104013
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Theaflavins (TF) are water-soluble pigments in tea. They possess rich biological activities such as antioxidant, antibacterial, alleviating metabolic syndrome, anti-inflammatory, tooth-protecting, neuroprotective, and antidepressant effects, and thus have broad application prospects. Given the complex structure, unstable chemical properties, low extraction efficiency, and the difficulty in obtaining TF, the oxidative preparation of TF has attracted significant attention. Oxidation preparation methods of TF include the chemical method and the enzymatic method. Chemical method utilizes a chemical oxidant. It features a uniform oxidation degree and strong controllability, and generates more ester TF in an acidic environment. However, the chemical oxidation method has poor specificity. Consequently, it is necessary to protect the hydroxyl group on the catechin A-ring to enhance the yield of TF. Moreover, the amount of oxidant required is large, and safety is a concern. In enzymatic preparation, polyphenol oxidase and peroxidase are employed. The conditions are mild, efficient, and specific. Efficiency of enzymatically preparing TF is influenced by the sources and types of oxidases, substrate composition, and reaction parameters. Yield of TF can be increased by preferentially oxidizing the oxidases of catechol catechins, increasing the proportion of biphenyl catechins, and reacting for an extended period in a weak-acid and low-temperature environment. Nevertheless, the current preparation methods still face problems such as a low extraction rate and low product purity. This paper discussed 2 kinds of oxidation preparation methods, and summarized their biological activities, in order to provide reference for the industrial production and application research of TF.

theaflavin  /  oxidation preparation  /  enzymatic preparation  /  biological activity
Zhi-Yuan WANG, Ya-Fei ZHAO, Ze-Ping WU, Xiao-Qiang CHEN, Xiao-Lei LU. Research progress on oxidation preparation methods and biological activity of theaflavins[J]. Journal of Food Safety & Quality, 2025 , 16 (3) : 83 -93 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20241104013
Year 2025 volume 16 Issue 3
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20241104013
  • Receive Date:2024-11-04
  • Online Date:2025-07-21
  • Published:2025-02-15
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  • Received:2024-11-04
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    1. School of Life and Health Sciences, Hubei University of Technology, Wuhan 430068, China
    2. Hangzhou Tea Research Institute, CHINA COOP, Hangzhou 310016, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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