Objective To establish a method for simultaneous determination of 5 kinds of heavy metals [lead (Pb), cadmium (Cd), arsenic (As), mercury (Hg), copper (Cu)] and harmful elements in longan lour by inductively coupled plasma-mass spectrometry (ICP-MS), and to evaluate the safety of longan lour. Methods Microwave digestion-ICP-MS was used to determine 5 kinds of heavy metals and harmful elements in longan lour, single factor pollution index method and Nemero comprehensive pollution index method were used for pollution assessment, the health risk assessment was carried out according to 4 steps: Hazard identification, hazard characterization, exposure assessment and risk characterization. Results The 5 kinds of elements had a good linear relationship (r>0.999) within a certain content range, the recovery rates were 97.5%-106.8%, and relative standard deviations were 0.11%-2.52%, indicating that the method was accurate and reliable. According to the heavy metal and harmful element limit standards for medicinal materials and decoction pieces in the Pharmacopoeia of the People’s Republic of China (2020 edition), longan lour from one producing region exceeded the Pb limit, with a non-compliance rate of 5%. Safety evaluation studies revealed that samples from 3 producing regions were contaminated with heavy metals and harmful elements to varying degrees, while those from the remaining 17 regions were safe. Health risk assessment studies indicated that Pb and As exposure from longan lour in a small number of producing regions might pose certain non-carcinogenic health risks to humans, warranting attention. Conclusion The model established in this study effectively assesses the health risks of heavy metals and harmful elements in longan lour, providing reference data for formulating limit standards for heavy metals in longan lour and offering a scientific basis for establishing a safety evaluation system for this medicinal material.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |