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Research progress on co-culture and application of mesenchymal stem cells and nerve cells
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Ming-Yi Liu1, Zi-Bin Zhang1, Jia-Yue Shi1, Yu-Xuan Ma1, Kai Jiao2, Li-Na Niu1, *
Medical Journal of Chinese People’s Liberation Army | 2022, 47(12) : 1256 - 1261
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Medical Journal of Chinese People’s Liberation Army | 2022, 47(12): 1256-1261
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Research progress on co-culture and application of mesenchymal stem cells and nerve cells
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Ming-Yi Liu1, Zi-Bin Zhang1, Jia-Yue Shi1, Yu-Xuan Ma1, Kai Jiao2, Li-Na Niu1, *
Affiliations
  • 1State Key Laboratory of Military Stomatology/National Clinical Research Center for Oral Diseases/Shaanxi Key Laboratory of Stomatology/Department of Prosthodontics, School of Stomatology, Air Force Military Medical University, Xi’ an, Shaanxi 710032, China
  • 2State Key Laboratory of Military Stomatology/National Clinical Research Center for Oral Diseases/Shaanxi Clinical Research Center for Oral Diseases/Department of Mucosal Diseases, School of Stomatology, Air Force Military Medical University, Xi’an, Shaanxi 710032, China
Published: 2022-12-28 doi: 10.11855/j.issn.0577-7402.2022.12.1256
Outline
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Co-culture is an important technique to study specific biological problems, and has been widely applied recent years in the field of nervous system diseases which are characterized by diversity, commonality and intractability, and have always been a medical problem that researchers are committed to overcoming. The co-culture of mesenchymal stem cells (MSCs) and nerve cells provides hope for treatment of nervous system diseases. As a systemically designed and controlled environment, co-culture technology can be used to explore the morphology and function of nerve cells under physiological, pathological or toxic conditions, as well as the molecular events of intercellular interaction. Neurogenesis and nerve regeneration directed by MSCs will have a significant impact on therapeutic strategies for neurological diseases in the future. The research progress in co-culture of MSCs and nerve cells has been systematically reviewed in present paper, and described the application prospect of co-culture model, so as to provide ideas for the treatment of nervous system diseases.

mesenchymal stem cells  /  neurons  /  co-culture techniques  /  neuroglia  /  nervous system diseases
Ming-Yi Liu, Zi-Bin Zhang, Jia-Yue Shi, Yu-Xuan Ma, Kai Jiao, Li-Na Niu. Research progress on co-culture and application of mesenchymal stem cells and nerve cells[J]. Medical Journal of Chinese People’s Liberation Army, 2022 , 47 (12) : 1256 -1261 . DOI: 10.11855/j.issn.0577-7402.2022.12.1256
Funding
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  • National Natural Science Foundation of China(81870805)
  • Shaanxi Key Scientific and Technological Innovation Team Project(2020TD-033)
Appendix
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Year 2022 volume 47 Issue 12
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206
96
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Article Info
doi: 10.11855/j.issn.0577-7402.2022.12.1256
  • Receive Date：2021-12-22
  • Online Date：2025-12-14
  • Published：2022-12-28
Article Data
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History
  • Received：2021-12-22
  • Accepted：2022-06-08
Funding
National Natural Science Foundation of China(81870805)
Shaanxi Key Scientific and Technological Innovation Team Project(2020TD-033)
Affiliations
    1State Key Laboratory of Military Stomatology/National Clinical Research Center for Oral Diseases/Shaanxi Key Laboratory of Stomatology/Department of Prosthodontics, School of Stomatology, Air Force Military Medical University, Xi’ an, Shaanxi 710032, China
    2State Key Laboratory of Military Stomatology/National Clinical Research Center for Oral Diseases/Shaanxi Clinical Research Center for Oral Diseases/Department of Mucosal Diseases, School of Stomatology, Air Force Military Medical University, Xi’an, Shaanxi 710032, China

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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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