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Heart failure is the end stage of various cardiovascular diseases. Its pathological process is complex and regulated by many factors. With population aging intensifying, the prevalence rate of heart failure is increasing. MicroRNA (miRNA)participates in the development and growth of the body and plays an important role in the occurrence and development of heart failure. In addition, miRNA could be used as a marker and a target of treatment on heart failure. In this paper, CiteSpace was used to conduct bibliometric analysis on research on miRNA and heart failure, and keyword clustering and emergence was used to judge the research frontier in this field, that is, miRNA changes participate in the regulation of myocardial hypertrophy and myocardial fibrosis in the occurrence and development of heart failure. It is summarized research progress on traditional Chinese and Western medicine improving heart failure by regulating miRNA.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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