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To explore the efficacy and influencing factors of intraorbital electroacupuncture in the treatment of diabetic oculomotor nerve palsy.
The clinical data of patients with diabetic oculomotor nerve palsy who received intraorbital electroacupuncture therapy in the First Affiliated Hospital of Harbin Medical University from January 2020 to November 2024 were retrospectively analyzed. Demographic characteristics, ocular motor nerve palsy score, glycosylated hemoglobin, course of oculomotor nerve palsy, course of diabetes, number of treatments, and maximum deflection angle of diplopia in horizontal and vertical directions were extracted from the electronic medical record system. The T test/Mann-Whitney U test was used to compare the difference between the cured group and the non-cured group, and the binary logistic regression was used to analyze the influencing factors of the curative effect.
Of the 167 patients, 67 were cured, 96 were effective, and 4 were ineffective. The overall cure rate was 40.1%, and the total effective rate was 97.6%. The symptoms of diplopia were alleviated after treatment. There was a statistically significant difference in the median value of the maximum horizontal (α) and maximum vertical (β) diplopia angle before and after treatment (P <0.001). After treatment, the maximum value of α in 67 cured patients was 6°, and the minimum value was 0°, with a confidence interval of 1.289-2.598. The maximum value of β is 5°, the minimum value is 0°, and the confidence interval is 1.113 ~ 2.462. Univariate analysis showed that there were significant differences in ocular motor nerve palsy score, glycosylated hemoglobin, treatment times and treatment days between the cured group and the non-cured group (P < 0.05). Regression analysis showed that the number of treatments was an effective protective factor for acupuncture (β =0.050, P < 0.001). Glycosylated hemoglobin was a risk factor (β =-0.248, P = 0.026).
Intraorbital electroacupuncture can effectively improve the symptoms of ptosis, diplopia and eye movement disorder in patients with diabetic oculomotor nerve palsy. The curative effect is positively correlated with the mild degree of oculomotor nerve palsy, stable blood glucose control and sufficient course of treatment.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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