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Effects of Modified Sangbaipi Decoction on Therapeutic Efficacy and Pulmonary Function in Patients with Acute Exacerbation of COPD (Phlegm-Heat Obstructing Lung Syndrome)
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Haiyue ZHONG, Ning ZHANG, Jingshuai FENG, Dayong XIN*
Acta Chinese Medicine and Pharmacology | 2026, 54(5) : 73 - 76
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Acta Chinese Medicine and Pharmacology | 2026, 54(5): 73-76
Effects of Modified Sangbaipi Decoction on Therapeutic Efficacy and Pulmonary Function in Patients with Acute Exacerbation of COPD (Phlegm-Heat Obstructing Lung Syndrome)
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Haiyue ZHONG, Ning ZHANG, Jingshuai FENG, Dayong XIN*
Affiliations
  • Department of Respiratory, Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing 101300, China
Published: 2026-05-20 doi: 10.19664/j.cnki.1002-2392.260100
Outline
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Objective:

To investigate the efficacy of modified Sangbaipi Decoction on patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and its effect on pulmonary function.

Methods:

A total of 120 patients with acute exacerbation of COPD admitted to Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, from June 2023 to June 2025 were selected and randomly divided into a control group (conventional Western medicine treatment) and an observation group (conventional Western medicine + modified Sangbaipi Decoction treatment) with 60 cases each. Observed and compared the TCM Syndrome Score, clinical efficacy, pulmonary function indices, inflammatory factors and the incidence of adverse reactions in both groups.

Results:

The total effectiveness rate of the observation group after treatment were higher than that of the control group (P < 0.05) ; The TCM syndrome score subjects group was lower than that of the control group (P <0.05). After treatment, the levels of FEV1, FVC and FEV1/FVC in both groups were increased and the levels of IL-6, CRP and PCT were decreased (P < 0.05), and the observation group was lower than that of the control group (P < 0.05). There was no apparent difference in the incidence of adverse reactions between both groups (P > 0.05).

Conclusion:

Modified Sangbaipi Decoction has significant efficacy in patients with acute exacerbation of COPD (Phlegm-heat obstructing lung syndrome), can effectively improve the clinical symptoms and pulmonary function indices, reduce the level of inflammatory factors, and it has a high degree of safety.

Sangbaipi Decoction  /  Chronic obstructive pulmonary disease  /  Acute exacerbation  /  Phlegm-heat obstructing lung syndrome  /  Pulmonary function
Haiyue ZHONG, Ning ZHANG, Jingshuai FENG, Dayong XIN. Effects of Modified Sangbaipi Decoction on Therapeutic Efficacy and Pulmonary Function in Patients with Acute Exacerbation of COPD (Phlegm-Heat Obstructing Lung Syndrome)[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (5) : 73 -76 . DOI: 10.19664/j.cnki.1002-2392.260100
Year 2026 volume 54 Issue 5
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doi: 10.19664/j.cnki.1002-2392.260100
  • Receive Date:2025-05-13
  • Online Date:2026-09-17
  • Published:2026-05-20
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  • Received:2025-05-13
  • Revised:2026-01-14
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    Department of Respiratory, Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing 101300, China
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表12种不同金属材料的力学参数

Family
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Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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