PDF
Full
Outline
To investigate epidemiological trends in pulmonary nodule detection, characterize the distribution patterns of nodule size, morphology, anatomical location, and multiplicity, analyze gender- and age-related correlations, and propose Traditional Chinese Medicine (TCM)-based intervention strategies.
A retrospective cohort analysis was conducted using low-dose computed tomography (LDCT) data from 5 426 individuals undergoing routine health screenings at Liaocheng Hospital of Traditional Chinese Medicine from January to December 2024, identifying 4 076 patients with pulmonary nodules. Statistical analyses, including chi-square tests and Fisher's exact tests, were performed using SPSS 23.0.
Pulmonary nodule detection rates demonstrated a progressive increase in recent years, peaking in 2022, followed by stabilization in 2024. Nodule characteristics revealed a predominance of solid nodules (70.6%), micro-nodules (< 10 mm, 73.3%), and multiple nodules (84.3%). Anatomically, the right upper lobe exhibited the highest nodule prevalence (20.8%). Gender-specific analysis identified significant disparities: females displayed a higher proportion of multiple nodules (P < 0.05) and ground-glass opacity (GGO) nodules (33.7% vs. 23.0% in males), whereas males exhibited a greater prevalence of solid nodules (75.5% vs. 64.7%). Age-stratified comparisons indicated markedly higher detection rates in middle-aged and elderly cohorts (≥40 years) versus younger groups (P <0.05), with larger nodules (≥10 mm) more frequent in older populations (3.0% vs. 0.8%). Notably, part-solid nodules constituted the predominant subtype among larger lesions (27.3%). TCM Constitution distribution showed that the top four biased constitutions were phlegm dampness constitution (19.9%), qi stagnation constitution (15.0%), Qi deficiency constitution (12.0%), and blood stasis constitution (10.0%).
Gender and age significantly influence pulmonary nodule characteristics, with part-solid morphology being disproportionately associated with larger nodules, underscoring the necessity for enhanced malignancy risk stratification in such cases. The centralized distribution of TCM Constitution further confirms the core pathogenesis of qi stagnation and phlegm coagulation. This study establishes foundational epidemiological data for pulmonary nodule management in asymptomatic populations and integrates TCM theoretical frameworks into clinical strategies. However, longitudinal follow-up and comprehensive adjustment for confounders are required to validate these findings and optimize therapeutic approaches.
PDF
3
0
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
