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To explore the clinical efficacy of Tiaogan Xifeng (Liver-Regulating and Wind-Extinguishing) Acupuncture Therapy combined with conventional western medicine to treat children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome).
88 children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome) who were treated in Kaifeng Hospital of Traditional Chinese Medicine from September 2022 to January 2025 were selected for the study, and they were randomly divided into two groups, and the each group had 44 cases. The western medicine group received conventional western medicine therapy treatment, while the combination group received Tiaogan Xifeng Acupuncture Therapy on the basis of western medicine group. The traditional Chinese medicine syndrome scores, severity of symptoms [Yale global tic severity scale (YGTSS)], and neurotransmitter levels [Norepinephrine (NE), γ-aminobutyric acid (GABA), dopamine (DA)] of children before and after treatment were compared in two groups, and the clinical efficacy and adverse drug reactions in two groups of children were compared.
After treatment, the traditional Chinese medicine syndrome score, YGTSS score and the levels of NE and DA in two groups decreased (P < 0. 05), and those in the combination group were lower (P < 0.05). After treatment, the level of GABA in two groups increased (P <0.05), and that in combination group was higher (P < 0.05). The total effective rate of treatment in the combination group was higher than that in the western medicine group (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions among in two groups (P > 0.05).
The Tiaogan Xifeng Acupuncture Therapy combined with conventional western medicine to treat children with tourette's syndrome (spleen deficiency and liver hyperactivity syndrome) has good clinical efficacy, and the patient's condition and neurotransmitter levels have significantly improved, and the risk of adverse reactions in children is low.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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