Based on the theory of" Kidney Governing Reproduction", the clinical efficacy of Yushen Zhuyun Formula in treating ovulation dysfunction infertility was discussed.

A total of 102 patients with ovulatory infertility admitted to Nanyang Second General Hospital from January 2022 to January 2024 were selected and randomly divided into a control group (conventional western medicine treatment) and a study group (conventional western medicine + treatment of Yushen Zhuyun Formula) with 51 cases in each group. Record and compare the clinical curative effect of TCM syndrome integral, the two groups, ultrasonic index, sex hormone [serum luteinizing hormone (LH), estradiol (E₂), follicle-stimulating hormone (FSH)] level and incidence of adverse reactions.

After treatment, two groups of TCM syndrome integral are lower than before the treatment, and the team was lower (P <0.05). After treatment, clinical treatment group total effective rate was 92.16%, 76.47% higher than the control group (P <0.05). After treatment, the number of dominant follicles was more in both groups than before treatment, and more in the study group (P <0. 05). Two groups of dominant follicle diameter and the thickness of endometrium is higher than before the treatment, and the group is higher (P < 0.05). After treatment, two groups of LH, FSH level was reduced, the E₂ levels are higher, and larger variations in team (P < 0.05). During the treatment period, the incidence of adverse reactions in the study group was 5.82%, which was lower than that in the control group 15. 69% (P > 0.05). The natural pregnancy rate in the study group was 41.18%, which was higher than the 21.57% in the control group (P < 0.05).

The Yushen Zhuyun Formula, based on the theory of "Kidney Governing Reproduction", has significant effect on ovulation dysfunction infertility patients, can effectively promote follicle and endometrial development, regulate the recovery of sex hormone levels, with a low incidence of adverse reactions.