PDF
Full
Outline
To explore and analyze the application effect of Banxia Xiexin Decoction on patients with locally advanced gastric cancer during postoperative SOX regimen chemotherapy, and to analyze its influence on immunity and nutritional status of patients.
A total of 118 patients with locally advanced gastric cancer who visited department of gastrointestinal surgery of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from May 2021 to May 2024 were included. They were randomly divided into the conventional group and the combined group using a random number table (simple random grouping method), with 59 cases in each group. The patients in the conventional group received SOX regimen chemotherapy after surgery, whereas the patients in the combined group were added with Banxia Xiexin Decoction. The changes of tumor factors, immune factors, gastrointestinal function and nutritional indicators were observed in the two groups after treatment.
After treatment, the levels of carcinoembryonic antigen, vascular endothelial growth factor, matrix metalloproteinase-9 and other tumor factors in the combined group were lower than those in the conventional group (P < 0.05). The levels of diamine oxidase and fecal calprotectin in the combined group were lower while the level of motilin was higher compared to the conventional group (P <0.05). The neutrophil-to-lymphocyte ratio and interleukin-6 in the combined group were lower compared with those in the conventional group while the proportion of CD8 + T was higher (P <0.05). The levels of albumin, prealbumin and transferrin and body mass in the combined group were higher than those in the conventional group (P <0.05). In terms of treatment safety, the incidence rates of adverse chemotherapy reactions were lower in the combined group compared to the conventional group (P <0.05).
Banxia Xiexin Decoction can reduce the levels of tumor factors, promote the improvements of gastrointestinal function, immunity and nutritional status, and play a role in reducing toxicity and increasing efficiency in patients with locally advanced gastric cancer receiving SOX regimen chemotherapy after surgery.
PDF
36
10
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
