Full
Outline
Dysregulation of the mitochondrial quality control（MQC）system is a key factor in the development of post-arrest myocardial dysfunction（PAMD）.Traditional Chinese medicine can target the regulation of the mitochondrial quality control system through mechanisms such as mitochondrial biogenesis，mitochondrial dynamics，mitochondrial energy metabolism，calcium overload，mitochondrial oxidative stress，and mitochondrial autophagy and apoptosis，thereby preventing and treating post-arrest myocardial dysfunction.The treatment is notable for its efficacy and advantages of multi-component，multi-target，and multi-level action.Targeting MQC to restore cellular homeostasis has become an important research direction for the prevention and treatment of PAMD.However，the following issues still exist in this field:In the MQC system，apart from the main pathways，other regulatory mechanisms remain unclear and require further investigation；research on TCMinterventions in MQC is still in its early stages，with the drug targets and mechanisms not yet fully understood，necessitating further analysis of their multi-component and multi-target regulatory mechanisms using techniques such as bioinformatics and molecular docking；most existing studies are based on animal or cell experiments，and future efforts should focus on strengthening clinical translational research to promote the translation of basic research findings into clinical treatment strategies，providing a more solid theoretical basis and practical support for TCMprevention and treatment of PAMD.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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