Article(id=1322923750487892629, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2025.05.041, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793339200851, onlineDateStr=2026-10-30, pubDate=1746806400000, pubDateStr=2025-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793339200851, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793339200851, creator=13701087609, updateTime=1793339200851, updator=13701087609, issue=Issue{id=1322923490592043032, tenantId=1146029695717560320, journalId=1255847919539208197, year='2025', volume='43', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1746806400000', pubDateStr='2025-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793339138887, creator='13701087609', updateTime=1793340572227, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322929502539612595, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322929502539612596, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=222, endPage=225, ext={EN=ArticleExt(id=1322923750689219222, articleId=1322923750487892629, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effect of Anshen Buxin Liuwei Pills（安神补心六味丸）and Shugan Jieyu Capsules（舒肝解郁胶囊）on Prognosis of Post-Stroke Depression, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the clinical therapeutic effect of Mongolian medicine Anshen Buxin Liuwei Pills（安神补心六味丸）and Shugan Jieyu Capsules（舒肝解郁胶囊）on post-stroke depression.
Methods A total of 120 patients with post-ischemic stroke depression due to liver stasis and phlegm coagulation syndrome were selected and randomly divided into a control group and an observation group，with 60 cases in each group. On the basis of conventional treatment，the control group was treated with fluoxetine hydrochloride dispersible tablets while the observation group was treated with Anshen Buxin Liuwei Pills and Shugan Jieyu Capsules. The course of treatment for both groups was 8 weeks. The clinical treatment effects，traditional Chinese medicine（TCM）syndrome scores，Hamilton Depression Scale（HAMD）scores，Modified Edinburgh Scandinavian Survival Score（MESSS），serum levels of 5-hydroxytryptamine（5-HT），norepinephrine（NE），brain-derived neurotrophic factor（BDNF）and Brarthel index（BI）between the two groups before treatment and at the 4th and 8th week of treatment were compared.
Results The total effective rate of the observation group reached 93.33%（56/60）after treatment，which was significantly better than that（80.00%，48/60）of the control group（P<0.05）. The TCM syndrome scores of the patients in both groups showed a trend of significant reduction at the 4th and 8th week of treatment（P<0.05），and at the same time，it could be seen that the scores of the observation group were significantly lower than those of the control group（P<0.05）. The scores of HAMD and MESSSwere significantly lower than those before treatment（P<0.05），while the scores of the observation group were significantly lower than those of the control group（P<0.05）. In both groups，the serum levels of 5-HT，NE and BDNF were significantly higher than those before treatment at the 4th and 8th week of treatment（P<0.05），while the serum levels of 5-HT，NE and BDNF in the observation group were also higher than those in the control group（P<0.05）. BI indexes were higher than those before treatment at the 4th and 8th week of treatment in both groups（P<0.05），while BIindex in the observation group was significantly higher than that in the control group（P<0.05）.
Conclusion Mongolian medicine Anshen Buxin Liuwei Pills combined with Shugan Jieyu Capsules can significantly improve the clinical efficacy of patients with post-ischemic stroke depression due to liver stasis and phlegm coagulation syndrome，reduce the degree of depression，promote the recovery of neurological function and increase the serum levels of 5-HT，NE and BDNF，thereby improving the quality of life and improving prognosis.
, authors=Limei LI, Qingmin LI, Jinglan DAI, Jinquan HE, authorsList=Limei LI, Qingmin LI, Jinglan DAI, Jinquan HE, authorCompany=null, correspAuthors=Jinquan HE, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322923751922344607, articleId=1322923750487892629, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=蒙药安神补心六味丸合舒肝解郁胶囊对脑卒中后抑郁的预后影响分析, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探究蒙药安神补心六味丸合舒肝解郁胶囊对脑卒中后抑郁的临床治疗效果。
方法 选取肝瘀痰凝证缺血性脑卒中后抑郁患者120例，并将其随机分为对照组及观察组，每组60例。两组患者在常规治疗的基础上，对照组给予盐酸氟西汀胶囊治疗，观察组则给予蒙药安神补心六味丸合舒肝解郁胶囊治疗，两组疗程均为8周，分别在治疗前、治疗第4周及治疗第8周对比两组患者临床治疗效果、中医证候评分、汉密尔顿抑郁量表（hamilton depression scale，HAMD）评分、改良爱丁堡-斯堪的纳维亚（modified Edinburgh-Scandinavian survival score，MESSS）评分、血清5-羟色胺（5-hydroxytryptamine，5-HT）、去甲肾上腺素（noradrenaline，NE）、脑源性神经营养因子（brain-derived neurotrophic facto，BDNF）及Brarthel指数（Brarthel index，BI）。
结果 治疗后观察组的总有效率达到93.33%（56/60），显著优于对照组的80.00%（48/60）（P<0.05）；两组患者在治疗第4周和第8周时，中医证候评分均较治疗前显著减少（P<0.05），同时可见观察组评分显著低于对照组（P<0.05）；两组患者在治疗第4周和第8周时，HAMD及MESSS评分均较治疗前显著降低（P<0.05），同时观察组评分均较对照组显著降低（P<0.05）。两组患者在治疗第4周和第8周时，血清5-HT、NE及BDNF水平均较治疗前显著升高（P<0.05），同时观察组血清5-HT、NE、BDNF水平也显著高于对照组（P<0.05）；两组患者治疗第4周和第8周时，BI指数均较治疗前显著升高（P<0.05），同时观察组BI指数也显著高于对照组（P<0.05）。
结论 蒙药安神补心六味丸合舒肝解郁胶囊能显著提高肝郁痰凝证缺血性脑卒中后抑郁患者的临床疗效，减轻患者抑郁程度，并且促进患者的神经功能恢复，提高血清5-HT、NE及BDNF水平，从而提升患者生存质量，改善预后。
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李丽梅（1983-），女，湖南郴州人，副主任医师，硕士，研究方向：精神病学。
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等. 内蒙古自治区7472例脑卒中发病流行病学特征分析［J］.
疾病监测，
2022，
37（4）：464-468., articleTitle=内蒙古自治区7472例脑卒中发病流行病学特征分析, refAbstract=null), Reference(id=1322923756326363852, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2020, volume=37, issue=5, pageStart=486, pageEnd=491, url=null, language=null, rfNumber=［2］, rfOrder=1, authorNames=安吉, 郭默宁, 谭鹏, journalName=环境与职业医学, refType=null, unstructuredReference=安吉，郭默宁，谭鹏，
等. 基于分布滞后非线性模型评估气温对北京市居民缺血性脑卒中入院人数的影响［J］.
环境与职业医学，
2020，
37（5）：486-491., articleTitle=基于分布滞后非线性模型评估气温对北京市居民缺血性脑卒中入院人数的影响, refAbstract=null), Reference(id=1322923756489941709, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=37, issue=12, pageStart=7249, pageEnd=7251, url=null, language=null, rfNumber=［3］, rfOrder=2, authorNames=李轶璠, 赵永辰, 张冬立, journalName=中华中医药杂志, refType=null, unstructuredReference=李轶璠，赵永辰，张冬立，
等. 从中医体质论卒中后抑郁的研究进展［J］.
中华中医药杂志，
2022，
37（12）：7249-7251., articleTitle=从中医体质论卒中后抑郁的研究进展, refAbstract=null), Reference(id=1322923756716434126, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2023, volume=41, issue=6, pageStart=221, pageEnd=224, url=null, language=null, rfNumber=［4］, rfOrder=3, authorNames=段红莉, 佟茜, 王雅娟, journalName=中华中医药学刊, refType=null, unstructuredReference=段红莉，佟茜，王雅娟，
等. 培元涤痰开郁方联合调督通脑针刺对痰瘀证缺血性卒中后抑郁的临床效果分析［J］.
中华中医药学刊，
2023，
41（6）：221-224., articleTitle=培元涤痰开郁方联合调督通脑针刺对痰瘀证缺血性卒中后抑郁的临床效果分析, refAbstract=null), Reference(id=1322923756859040463, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2023, volume=41, issue=6, pageStart=200, pageEnd=203, url=null, language=null, rfNumber=［5］, rfOrder=4, authorNames=谢先龙, 叶勇, 吴艳霞, journalName=中华中医药学刊, refType=null, unstructuredReference=谢先龙，叶勇，吴艳霞，
等. 安神合剂与黛力新合用对脑卒中后抑郁-焦虑共病神经功能缺损、负性心理及不良反应的影响［J］.
中华中医药学刊，
2023，
41（6）：200-203., articleTitle=安神合剂与黛力新合用对脑卒中后抑郁-焦虑共病神经功能缺损、负性心理及不良反应的影响, refAbstract=null), Reference(id=1322923758561927888, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=19, issue=29, pageStart=94, pageEnd=96，100, url=null, language=null, rfNumber=［6］, rfOrder=5, authorNames=韩莉, journalName=中国医药导报, refType=null, unstructuredReference=韩莉. 高精度经颅直流电刺激联合盐酸氟西汀治疗脑卒中后抑郁伴睡眠障碍的效果［J］.
中国医药导报，
2022，
19（29）：94-96，100., articleTitle=高精度经颅直流电刺激联合盐酸氟西汀治疗脑卒中后抑郁伴睡眠障碍的效果, refAbstract=null), Reference(id=1322923758650008273, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=42, issue=18, pageStart=4617, pageEnd=4621, url=null, language=null, rfNumber=［7］, rfOrder=6, authorNames=黄海鹏, 于斌, 管其凡, journalName=中国老年学杂志, refType=null, unstructuredReference=黄海鹏，于斌，管其凡，
等. 针刺治疗脑卒中后抑郁的临床研究进展［J］.
中国老年学杂志，
2022，
42（18）：4617-4621., articleTitle=针刺治疗脑卒中后抑郁的临床研究进展, refAbstract=null), Reference(id=1322923758729700050, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2023, volume=41, issue=3, pageStart=190, pageEnd=193, url=null, language=null, rfNumber=［8］, rfOrder=7, authorNames=王保国, 肖伟, 王震, journalName=中华中医药学刊, refType=null, unstructuredReference=王保国，肖伟，王震，
等. “通督治郁”针法治疗脑卒中后抑郁对临床症状及血清5-HT、NE、DA的影响［J］.
中华中医药学刊，
2023，
41（3）：190-193., articleTitle=“通督治郁”针法治疗脑卒中后抑郁对临床症状及血清5-HT、NE、DA的影响, refAbstract=null), Reference(id=1322923758805197523, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=1996, volume=29, issue=6, pageStart=379, pageEnd=null, url=null, language=null, rfNumber=［9］, rfOrder=8, authorNames=中华神经科学会, journalName=中华神经科杂志, refType=null, unstructuredReference=中华神经科学会. 各类脑血管病诊断要点［J］.
中华神经科杂志，
1996，
29（6）：379., articleTitle=各类脑血管病诊断要点, refAbstract=null), Reference(id=1322923758863917780, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2012, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［10］, rfOrder=9, authorNames=吴勉华, 王新月, journalName=中医内科学, refType=null, unstructuredReference=吴勉华，王新月.
中医内科学［M］. 3版. 北京：中国中医药出版社，
2012., articleTitle=null, refAbstract=null), Reference(id=1322923758935220949, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2012, volume=null, issue=null, pageStart=31, pageEnd=32, url=null, language=null, rfNumber=［11］, rfOrder=10, authorNames=国家中医药管理局医政司, journalName=null, refType=null, unstructuredReference=国家中医药管理局医政司. 中医病证诊断疗效标准［S］. 北京：中国中医药出版社，
2012：31-32., articleTitle=null, refAbstract=null), Reference(id=1322923759027495638, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=50, issue=18, pageStart=3174, pageEnd=3177，3181, url=null, language=null, rfNumber=［12］, rfOrder=11, authorNames=刘宝燕, 赵晋, 郑冬, journalName=重庆医学, refType=null, unstructuredReference=刘宝燕，赵晋，郑冬. HAMD与SDS区分抑郁症严重程度的准确性研究［J］.
重庆医学，
2021，
50（18）：3174-3177，3181., articleTitle=HAMD与SDS区分抑郁症严重程度的准确性研究, refAbstract=null), Reference(id=1322923759119770327, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=25, issue=3, pageStart=23, pageEnd=27, url=null, language=null, rfNumber=［13］, rfOrder=12, authorNames=张烨, 庄雪明, 虞大为, journalName=实用临床医药杂志, refType=null, unstructuredReference=张烨，庄雪明，虞大为，
等. 高迁移率族蛋白B1联合改良爱丁堡-斯堪的纳维亚评分评估急性脑梗死静脉溶栓患者预后的价值［J］.
实用临床医药杂志，
2021，
25（3）：23-27., articleTitle=高迁移率族蛋白B1联合改良爱丁堡-斯堪的纳维亚评分评估急性脑梗死静脉溶栓患者预后的价值, refAbstract=null), Reference(id=1322923759191073496, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=38, issue=12, pageStart=1517, pageEnd=1521, url=null, language=null, rfNumber=［14］, rfOrder=13, authorNames=张雪婷, 韩新源, 王暄齐, journalName=实用医学杂志, refType=null, unstructuredReference=张雪婷，韩新源，王暄齐，
等. 曲克芦丁联合高频电疗法对缺血性脑卒中患者血清中miR-137及miR-155表达的影响［J］.
实用医学杂志，
2022，
38（12）：1517-1521., articleTitle=曲克芦丁联合高频电疗法对缺血性脑卒中患者血清中miR-137及miR-155表达的影响, refAbstract=null), Reference(id=1322923759262376665, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=13, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［15］, rfOrder=14, authorNames=ZHANG M, BAI X, journalName=Front Pharmacol, refType=null, unstructuredReference=ZHANG M，BAI X. Shugan Jieyu capsule in post-stroke depression treatment：from molecules to systems［J］.
Front Pharmacol，
2022，
13：821270., articleTitle=Shugan Jieyu capsule in post-stroke depression treatment：from molecules to systems, refAbstract=null), Reference(id=1322923759337874138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=42, issue=11, pageStart=1216, pageEnd=1220, url=null, language=null, rfNumber=［16］, rfOrder=15, authorNames=尹正录, 葛晟, 黄灵慧, journalName=中国针灸, refType=null, unstructuredReference=尹正录，葛晟，黄灵慧，
等. 针刺联合重复经颅磁刺激治疗脑卒中后抑郁：随机对照试验［J］.
中国针灸，
2022，
42（11）：1216-1220., articleTitle=针刺联合重复经颅磁刺激治疗脑卒中后抑郁：随机对照试验, refAbstract=null), Reference(id=1322923759434343131, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=38, issue=8, pageStart=1246, pageEnd=1251, url=null, language=null, rfNumber=［17］, rfOrder=16, authorNames=喻斌, 阮鸣, 许立, journalName=中国药理学通报, refType=null, unstructuredReference=喻斌，阮鸣，许立，
等. 川芎注射液通过cAMP-CREB-BDNF通路改善卒中后抑郁大鼠神经功能［J］.
中国药理学通报，
2022，
38（8）：1246-1251., articleTitle=川芎注射液通过cAMP-CREB-BDNF通路改善卒中后抑郁大鼠神经功能, refAbstract=null), Reference(id=1322923759539200732, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=269, issue=3, pageStart=1236, pageEnd=1249, url=null, language=null, rfNumber=［18］, rfOrder=17, authorNames=GUOJL, WANG JJ, SUN W, journalName=J Neurol, refType=null, unstructuredReference=GUOJL，WANG JJ，SUN W，
et al. The advances of post-stroke depression：2021 update［J］.
J Neurol，
2022，
269（3）：1236-1249., articleTitle=The advances of post-stroke depression：2021 update, refAbstract=null), Reference(id=1322923759627281117, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=37, issue=6, pageStart=860, pageEnd=863, url=null, language=null, rfNumber=［19］, rfOrder=18, authorNames=赵紫岐, 马睿, 屈云, journalName=中国康复医学杂志, refType=null, unstructuredReference=赵紫岐，马睿，屈云. 基于临床实践的卒中后抑郁评估现状分析［J］.
中国康复医学杂志，
2022，
37（6）：860-863., articleTitle=基于临床实践的卒中后抑郁评估现状分析, refAbstract=null), Reference(id=1322923759698584286, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=40, issue=6, pageStart=124, pageEnd=128, url=null, language=null, rfNumber=［20］, rfOrder=19, authorNames=卞伟煜, 韩俊萍, 单永琳, journalName=四川中医, refType=null, unstructuredReference=卞伟煜，韩俊萍，单永琳，
等. 加味补阳还五汤联合经颅磁刺激治疗卒中后抑郁临床疗效及安全性分析［J］.
四川中医，
2022，
40（6）：124-128., articleTitle=加味补阳还五汤联合经颅磁刺激治疗卒中后抑郁临床疗效及安全性分析, refAbstract=null), Reference(id=1322923759769887455, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=168, issue=null, pageStart=74, pageEnd=88, url=null, language=null, rfNumber=［21］, rfOrder=20, authorNames=SARKAR A, SARMAH D, DATTA A, journalName=Brain Res Bull, refType=null, unstructuredReference=SARKAR A，SARMAH D，DATTA A，
et al. Post-stroke depression：chaos to exposition［J］.
Brain Res Bull，
2021，
168：74-88., articleTitle=Post-stroke depression：chaos to exposition, refAbstract=null), Reference(id=1322923759866356448, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=24, issue=S2, pageStart=49, pageEnd=52, url=null, language=null, rfNumber=［22］, rfOrder=21, authorNames=牛玉莲, 吴海威, journalName=中国全科医学, refType=null, unstructuredReference=牛玉莲，吴海威. 低频重复经颅磁刺激联合治疗卒中后抑郁患者疗效研究［J］.
中国全科医学，
2021，
24（S2）：49-52., articleTitle=低频重复经颅磁刺激联合治疗卒中后抑郁患者疗效研究, refAbstract=null), Reference(id=1322923759954436833, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=39, issue=12, pageStart=169, pageEnd=172, url=null, language=null, rfNumber=［23］, rfOrder=22, authorNames=卢婧, 梁春光, 侯艳玲, journalName=四川中医, refType=null, unstructuredReference=卢婧，梁春光，侯艳玲. 加味温胆汤联合帕罗西汀治疗脑卒中后抑郁伴焦虑共病的临床疗效及安全性研究［J］.
四川中医，
2021，
39（12）：169-172., articleTitle=加味温胆汤联合帕罗西汀治疗脑卒中后抑郁伴焦虑共病的临床疗效及安全性研究, refAbstract=null), Reference(id=1322923760013157090, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=24, issue=6, pageStart=76, pageEnd=79, url=null, language=null, rfNumber=［24］, rfOrder=23, authorNames=利永聪, 李建娴, 梁明坤, journalName=辽宁中医药大学学报, refType=null, unstructuredReference=利永聪，李建娴，梁明坤，
等. 柴胡疏肝散治疗卒中后抑郁肝气郁结证临床研究［J］.
辽宁中医药大学学报，
2022，
24（6）：76-79., articleTitle=柴胡疏肝散治疗卒中后抑郁肝气郁结证临床研究, refAbstract=null), Reference(id=1322923760080265955, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=39, issue=11, pageStart=202, pageEnd=205, url=null, language=null, rfNumber=［25］, rfOrder=24, authorNames=赵涵, 程一升, 张辉, journalName=中华中医药学刊, refType=null, unstructuredReference=赵涵，程一升，张辉. 醒脑解郁汤治疗卒中后抑郁的疗效及对血清NE、5-HT水平影响［J］.
中华中医药学刊，
2021，
39（11）：202-205., articleTitle=醒脑解郁汤治疗卒中后抑郁的疗效及对血清NE、5-HT水平影响, refAbstract=null), Reference(id=1322923760159957732, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=23, issue=23, pageStart=15114, pageEnd=null, url=null, language=null, rfNumber=［26］, rfOrder=25, authorNames=FRANK D, GRUENBAUM B F, ZLOTNIK A, journalName=Int J Mol Sci, refType=null, unstructuredReference=FRANK D，GRUENBAUM B F，ZLOTNIK A，
et al. Pathophysiology and current drug treatments for post-stroke depression：a review［J］.
Int J Mol Sci，
2022，
23（23）：15114., articleTitle=Pathophysiology and current drug treatments for post-stroke depression：a review, refAbstract=null), Reference(id=1322923760235455205, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=25, issue=12, pageStart=1481, pageEnd=1486, url=null, language=null, rfNumber=［27］, rfOrder=26, authorNames=朱宁, 段燕燕, 王娜, journalName=中国全科医学, refType=null, unstructuredReference=朱宁，段燕燕，王娜，
等. 理情行为疗法对卒中后抑郁患者睡眠及情绪的影响研究［J］.
中国全科医学，
2022，
25（12）：1481-1486., articleTitle=理情行为疗法对卒中后抑郁患者睡眠及情绪的影响研究, refAbstract=null), Reference(id=1322923760306758374, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=37, issue=16, pageStart=2058, pageEnd=2064, url=null, language=null, rfNumber=［28］, rfOrder=27, authorNames=李世明, 冯为, 崔凤伟, journalName=实用医学杂志, refType=null, unstructuredReference=李世明，冯为，崔凤伟，
等. 中国脑卒中后抑郁患病率meta分析［J］.
实用医学杂志，
2021，
37（16）：2058-2064., articleTitle=中国脑卒中后抑郁患病率meta分析, refAbstract=null), Reference(id=1322923760369672935, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=44, issue=7, pageStart=659, pageEnd=667, url=null, language=null, rfNumber=［29］, rfOrder=28, authorNames=张绍华, 王玉龙, 章春霞, journalName=北京中医药大学学报, refType=null, unstructuredReference=张绍华，王玉龙，章春霞，
等. 互动式头针对脑卒中后认知功能及抑郁、焦虑状态的临床研究［J］.
北京中医药大学学报，
2021，
44（7）：659-667., articleTitle=互动式头针对脑卒中后认知功能及抑郁、焦虑状态的临床研究, refAbstract=null), Reference(id=1322923760440976104, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=23, issue=6, pageStart=647, pageEnd=650, url=null, language=null, rfNumber=［30］, rfOrder=29, authorNames=王秀云, 李云, 朱含笑, journalName=中华老年心脑血管病杂志, refType=null, unstructuredReference=王秀云，李云，朱含笑，
等. 甘草苷对脑卒中后抑郁大鼠额前皮质脑源性神经营养因子及Bax和Bcl-2蛋白表达的影响［J］.
中华老年心脑血管病杂志，
2021，
23（6）：647-650., articleTitle=甘草苷对脑卒中后抑郁大鼠额前皮质脑源性神经营养因子及Bax和Bcl-2蛋白表达的影响, refAbstract=null), Reference(id=1322923760520667881, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=27, issue=4, pageStart=548, pageEnd=549，565, url=null, language=null, rfNumber=［31］, rfOrder=30, authorNames=王辉, 谢有良, 翟立武, journalName=中国中医基础医学杂志, refType=null, unstructuredReference=王辉，谢有良，翟立武，
等. 脑卒中后抑郁的情志病机探讨［J］.
中国中医基础医学杂志，
2021，
27（4）：548-549，565., articleTitle=脑卒中后抑郁的情志病机探讨, refAbstract=null), Reference(id=1322923760583582442, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=19, issue=1, pageStart=23, pageEnd=null, url=null, language=null, rfNumber=［32］, rfOrder=31, authorNames=FANG Y Q, DINGX, ZHANGY H, journalName=J Neuroinflammation, refType=null, unstructuredReference=FANG Y Q，DINGX，ZHANGY H，
et al. Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT
2B R/β-arrestin2 pathway［J］.
J Neuroinflammation，
2022，
19（1）：23., articleTitle=Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT
2B R/β-arrestin2 pathway, refAbstract=null), Reference(id=1322923760659079915, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2020, volume=38, issue=12, pageStart=84, pageEnd=86, url=null, language=null, rfNumber=［33］, rfOrder=32, authorNames=王波, 王天磊, 谭春凤, journalName=中华中医药学刊, refType=null, unstructuredReference=王波，王天磊，谭春凤，
等. 醒神启闭针刺法对脑卒中后抑郁的疗效及5-HT、NGF、IL-23的影响［J］.
中华中医药学刊，
2020，
38（12）：84-86., articleTitle=醒神启闭针刺法对脑卒中后抑郁的疗效及5-HT、NGF、IL-23的影响, refAbstract=null), Reference(id=1322923760726188780, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2022, volume=45, issue=9, pageStart=878, pageEnd=881, url=null, language=null, rfNumber=［34］, rfOrder=33, authorNames=徐向青, 曲淼, journalName=北京中医药大学学报, refType=null, unstructuredReference=徐向青，曲淼. “因郁致病”与“因病致郁”理论溯源及临证思考［J］.
北京中医药大学学报，
2022，
45（9）：878-881., articleTitle=“因郁致病”与“因病致郁”理论溯源及临证思考, refAbstract=null), Reference(id=1322923760810074861, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2023, volume=39, issue=3, pageStart=569, pageEnd=579, url=null, language=null, rfNumber=［35］, rfOrder=34, authorNames=黄雨佳, 黄先菊, 张曌, journalName=中国药理学通报, refType=null, unstructuredReference=黄雨佳，黄先菊，张曌，
等. 蒙药安神补心六味丸抗抑郁作用网络药理学机制研究［J］.
中国药理学通报，
2023，
39（3）：569-579., articleTitle=蒙药安神补心六味丸抗抑郁作用网络药理学机制研究, refAbstract=null), Reference(id=1322923760877183726, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, doi=null, pmid=null, pmcid=null, year=2021, volume=48, issue=4, pageStart=122, pageEnd=126, url=null, language=null, rfNumber=［36］, rfOrder=35, authorNames=李润霞, 张峥, 刘艳清, journalName=辽宁中医杂志, refType=null, unstructuredReference=李润霞，张峥，刘艳清. 疏肝解郁胶囊联合个性化愉悦元素积极刺激干预对脑卒中后抑郁患者5-HT、NE、DA的影响［J］.
辽宁中医杂志，
2021，
48（4）：122-126., articleTitle=疏肝解郁胶囊联合个性化愉悦元素积极刺激干预对脑卒中后抑郁患者5-HT、NE、DA的影响, refAbstract=null)], funds=[Fund(id=1322923755982430922, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, awardId=21C0711, language=CN, fundingSource=湖南省教育厅一般项目(21C0711), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1322923752144642720, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, xref=null, ext=[AuthorCompanyExt(id=1322923752157225633, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, companyId=1322923752144642720, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chenzhou First People＇s Hospital，Chenzhou 423000，Hunan，China), AuthorCompanyExt(id=1322923752165614242, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, companyId=1322923752144642720, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=郴州市第一人民医院，湖南 郴州 423000)])], figs=[ArticleFig(id=1322923754698973888, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 治愈 | 显效 | 有效 | 无效 | 总有效 |
|---|
| 对照组 | 60 | 15（25.00） | 16（26.67） | 17（28.33） | 12（20.00） | 48（80.00） |
| 观察组 | 60 | 24（40.00） | 22（36.67） | 10（16.67） | 4（6.67） | 56（93.33） |
| t值 | | | | | | 4.615 4 |
| P值 | | | | | | 0.031 7 |
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两组肝郁痰凝证缺血性脑卒中后抑郁患者临床疗效比较
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| 组别 | 例数 | 治愈 | 显效 | 有效 | 无效 | 总有效 |
|---|
| 对照组 | 60 | 15（25.00） | 16（26.67） | 17（28.33） | 12（20.00） | 48（80.00） |
| 观察组 | 60 | 24（40.00） | 22（36.67） | 10（16.67） | 4（6.67） | 56（93.33） |
| t值 | | | | | | 4.615 4 |
| P值 | | | | | | 0.031 7 |
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| 组别 | 例数 | 治疗前 | 治疗4周 | 治疗8周 |
|---|
| 对照组 | 60 | 25.23±4.41 | 19.33±2.17a | 15.06±1.95a |
| 观察组 | 60 | 25.30±4.25 | 14.02±1.27ab | 9.12±1.51ab |
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两组肝郁痰凝证缺血性脑卒中后抑郁患者中医证候评分比较（
±s）
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| 组别 | 例数 | 治疗前 | 治疗4周 | 治疗8周 |
|---|
| 对照组 | 60 | 25.23±4.41 | 19.33±2.17a | 15.06±1.95a |
| 观察组 | 60 | 25.30±4.25 | 14.02±1.27ab | 9.12±1.51ab |
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| 组别 | 例数 | 时间 | HAMD | MESSS |
|---|
| 对照组 | 60 | 治疗前 | 28.53±3.40 | 26.61±5.02 |
| | 治疗4周 | 17.42±2.89a | 18.73±5.23a |
| | 治疗8周 | 13.51±1.66a | 14.21±3.21a |
| 观察组 | 60 | 治疗前 | 28.49±3.38 | 26.57±5.16 |
| | 治疗4周 | 14.34±2.21ab | 15.21±4.24a |
| | 治疗8周 | 6.53±1.20ab | 9.03±2.52ab |
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两组肝郁痰凝证缺血性脑卒中后抑郁患者HAMD及MESSS评分对比（
±s）
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| 组别 | 例数 | 时间 | HAMD | MESSS |
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| 对照组 | 60 | 治疗前 | 28.53±3.40 | 26.61±5.02 |
| | 治疗4周 | 17.42±2.89a | 18.73±5.23a |
| | 治疗8周 | 13.51±1.66a | 14.21±3.21a |
| 观察组 | 60 | 治疗前 | 28.49±3.38 | 26.57±5.16 |
| | 治疗4周 | 14.34±2.21ab | 15.21±4.24a |
| | 治疗8周 | 6.53±1.20ab | 9.03±2.52ab |
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| 组别 | 例数 | 时间 | 5-HT/（ng/mL） | NE/（ng/mL） | BDNF/（mg/L） |
|---|
| 对照组 | 60 | 治疗前 | 75.34±8.23 | 4.33±0.35 | 8.02±1.42 |
| | 治疗4周 | 96.13±8.95a | 7.17±0.35a | 11.59±2.27a |
| | 治疗8周 | 139.55±10.90a | 10.22±0.64a | 16.88±2.88a |
| 观察组 | 60 | 治疗前 | 76.02±8.18 | 4.20±0.22 | 8.07±1.23 |
| | 治疗4周 | 123.93±9.33a | 10.74±0.24a | 15.64±2.86a |
| | 治疗8周 | 161.12±11.08ab | 15.85±0.65ab | 20.23±2.07ab |
), ArticleFig(id=1322923755571389127, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, language=CN, label=表4, caption=
两组肝郁痰凝证缺血性脑卒中后抑郁患者血清5-HT、NE及BDNF水平对比（
±s）
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| 组别 | 例数 | 时间 | 5-HT/（ng/mL） | NE/（ng/mL） | BDNF/（mg/L） |
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| 对照组 | 60 | 治疗前 | 75.34±8.23 | 4.33±0.35 | 8.02±1.42 |
| | 治疗4周 | 96.13±8.95a | 7.17±0.35a | 11.59±2.27a |
| | 治疗8周 | 139.55±10.90a | 10.22±0.64a | 16.88±2.88a |
| 观察组 | 60 | 治疗前 | 76.02±8.18 | 4.20±0.22 | 8.07±1.23 |
| | 治疗4周 | 123.93±9.33a | 10.74±0.24a | 15.64±2.86a |
| | 治疗8周 | 161.12±11.08ab | 15.85±0.65ab | 20.23±2.07ab |
), ArticleFig(id=1322923755684635336, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923750487892629, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
| 组别 | 例数 | 治疗前 | 治疗4周 | 治疗8周 |
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| 对照组 | 60 | 22.45±2.32 | 28.05±3.65a | 57.24±5.12a |
| 观察组 | 60 | 22.49±2.29 | 39.11±4.66a | 72.44±5.20ab |
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两组肝郁痰凝证缺血性脑卒中后抑郁患者BI指数对比（
±s）
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| 组别 | 例数 | 治疗前 | 治疗4周 | 治疗8周 |
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| 观察组 | 60 | 22.49±2.29 | 39.11±4.66a | 72.44±5.20ab |
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