Article(id=1322923604471587350, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2025.05.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793339166037, onlineDateStr=2026-10-30, pubDate=1746806400000, pubDateStr=2025-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793339166037, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793339166037, creator=13701087609, updateTime=1793339166037, updator=13701087609, issue=Issue{id=1322923490592043032, tenantId=1146029695717560320, journalId=1255847919539208197, year='2025', volume='43', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1746806400000', pubDateStr='2025-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793339138887, creator='13701087609', updateTime=1793340572227, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322929502539612595, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322929502539612596, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1322923490592043032, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=61, endPage=65, ext={EN=ArticleExt(id=1322923604823908888, articleId=1322923604471587350, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Comparison of Specific Odors of Different Processed Jiucaizi(Semen Allii Tuberosi)by GC-IMS, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective

To compare and analyze the differences of the special odors of Jiucaizi(Semen Allii Tuberosi)under different processing methods,such as raw products,stir-fried products with wine,stir-fried products with salt,stir-fried products with vinegar,stir-fried products with nothing,stir-fried products with salt and wine,steamed products. And to establish a method for distinguishing different processed products of Jiucaizi(Semen Allii Tuberosi)from their odors to provide a reference for further study of chemical transformation of Jiucaizi(Semen Allii Tuberosi).

Methods

GC-IMStechnology was used to detect volatile organic compounds in different processed products of Jiucaizi(Semen Allii Tuberosi)through the instrument combined with VOCal and plug-in Reporter,Gallery Plot and Dynamic PCA analysis from different angles including differential analysis,fingerprint analysis,dynamic principal component analysis,similarity analysis and qualitative analysis of differential substances.

Result

The difference analysis of GC-IMSshowed that there were significant differences in the specific odor components of Jiucaizi(Semen Allii Tuberosi)under different processing methods. About 54 compounds had been identified. Among them,geraniol,1-hydroxy-2-propanone,1-pentanol,2-methylpropanol,diallyl sulfide,Methyl-3-but-3-en-1-ol,ehanol,propanoic acid,2-acetylfuran,5-dimethylfuran,ethyl acetate,diallyl disulfide M,2-pentylfuran,hexanoic acid M and ethyl hexanoate can be used as the characteristic volatiles of the special odors of raw products. Ethyl 2-hydroxypropanoate and beta-Ocimene can be used as the characteristic volatiles of the special odors of Jiucaizi(Semen Allii Tuberosi)processed with wine or salt and wine;pentanal can be used as the characteristic volatiles of the special odors of stir-fried products with vinegar;3-hydroxy-2-butanone,butyrolactone and linalool could be used as the characteristic volatiles of steamed Jiucaizi(Semen Allii Tuberosi),and octanol could be used as the characteristic volatiles of stir-fried products with nothing. The PCA results showed that the separation of the samples was good,and the similarity of the samples with the same excipients was greater.

Conclusion

There are obvious differences in the specific odor components of Jiucaizi(Semen Allii Tuberosi)processed by different methods. GC-IMStechnology can be used as a method to distinguish the specific odor of different processed products of Jiucaizi(Semen Allii Tuberosi). It also provides reference for further study on the processing and transformation of Jiucaizi(Semen Allii Tuberosi).

, authors=Peng ZHOU, Xiaohong GUO, Jie LI, Juan CHEN, Dijia ZHAO, Wenhui WU, authorsList=Peng ZHOU, Xiaohong GUO, Jie LI, Juan CHEN, Dijia ZHAO, Wenhui WU, authorCompany=null, correspAuthors=Wenhui WU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322923608082883109, articleId=1322923604471587350, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=韭菜子不同炮制品特异性气味的GC-IMS比较, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的

对比分析韭菜子生品、酒炙品、盐炙品、醋炙品、清炒品、盐酒共炙品以及蒸熟品等不同炮制方法下特异性气味的差异,建立一种可从气味上区分韭菜子不同炮制品的方法,并为进一步研究韭菜子的炮制化学转化提供参考。

方法

采用气相色谱—离子迁移质谱(Gas chromatography-ion migration mass spectrometry,GC-IMS)技术对韭菜子不同炮制品的挥发性有机物进行检测,并结合VOCal、Reporter、Gallery Plot、Dynamic PCA等软件对GC-IMS谱图进行差异分析、指纹分析、动态主成分分析、相似度分析以及差异物质的定性分析。

结果

GC-IMS图谱的差异分析显示不同炮制方法下的韭菜子特异性气味成分存在显著差异,明确定性的差异物有54种。其中,香叶醇(Geraniol)、乙酰甲醇(1-hydroxy-2-propanone)、正戊醇(1-pentanol)、2-甲基丙醇(2-Methylpropanol)、烯丙基硫醚(diallyl sulfide)、3-甲基-3-丁烯-1-醇(Methyl-3-but-3-en-1-ol)、乙醇(Ethanol)、丙酸(Propanoic acid)、2-乙酰呋喃(2-acetylfuran)、2,5-二甲基呋喃(2,5-Dimethylfuran)、乙酸乙酯(ethyl acetate)、二烯丙基二硫M(Diallyl disulfide M)、正戊基呋喃(2-Pentylfuran)、己酸M(Hexanoic acid M)、己酸乙酯(Ethyl hexanoate)可作为韭菜子生品的特异性气味的特征挥发物质;2-羟基丙酸乙酯(ethyl 2-hydroxypropanoate)和β-罗勒烯(beta-Ocimene)可作为酒炙或盐酒共炙等辅料为酒的韭菜子炮制品的特异性气味的特征挥发物质;戊醛(pentanal)可作为醋炙韭菜子的特异性气味的特征挥发物质;呋喃甲醇(Furfuryl alcohol)、3-羟基-2-丁酮(3-hydroxy-2-butanone)、丁内酯(Butyrolactone)和芳樟醇(Linalool)可作为蒸熟韭菜子的特异性气味的特征挥发物质;辛醇(Octanol)可作为清炒韭菜子的特异性气味的特征挥发物质。PCA结果显示各组样品分离度良好,且具有相同辅料的样品相似度更大。

结论

韭菜子经不同方法炮制后其特异性气味成分存在明显差异,GC-IMS技术可作为一种区别韭菜子不同炮制品特异性气味的方法,并为进一步研究韭菜子的炮制转化提供参考。

, authors=周芃, 郭小红, 李杰, 陈娟, 赵迪加, 吴文辉, authorsList=周芃, 郭小红, 李杰, 陈娟, 赵迪加, 吴文辉, authorCompany=null, correspAuthors=吴文辉, authorNote=

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

, correspAuthorsNote=
吴文辉(1986-),男,四川绵阳人,副主任中药师,博士,研究方向:中药炮制原理。E-mail:。
, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=zDk905u1/052wozIjelJ0Q==, magXml=RTi0rn1cvjn0xMeJWZvgSA==, pdfUrl=null, pdf=Qqb6JoxOqsJIqEhqh6Fghw==, pdfFileSize=4333380, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=ctNNh0qYqPy1x+rmkv/yjg==, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=Jm1EUQUw2q6fvEM9C3e5NQ==, mapNumber=null, fund=null)}, authors=[Author(id=1322923608389067306, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608451981868, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608389067306, language=EN, stringName=Peng ZHOU, firstName=Peng, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608523285037, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608389067306, language=CN, stringName=周芃, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio={"content":"

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

"}, bioImg=null, bioContent=

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923608602976815, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608674279985, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608602976815, language=EN, stringName=Xiaohong GUO, firstName=Xiaohong, middleName=null, lastName=GUO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608741388850, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608602976815, language=CN, stringName=郭小红, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923608842052148, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608913355318, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608842052148, language=EN, stringName=Jie LI, firstName=Jie, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608988852791, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608842052148, language=CN, stringName=李杰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609085321785, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923609198567995, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609085321785, language=EN, stringName=Juan CHEN, firstName=Juan, middleName=null, lastName=CHEN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609290842684, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609085321785, language=CN, stringName=陈娟, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609378923070, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923609487974976, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609378923070, language=EN, stringName=Dijia ZHAO, firstName=Dijia, middleName=null, lastName=ZHAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609622192705, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609378923070, language=CN, stringName=赵迪加, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609697690179, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=cqwuwenhui@126.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1322923609806742085, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609697690179, language=EN, stringName=Wenhui WU, firstName=Wenhui, middleName=null, lastName=WU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609890628166, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609697690179, language=CN, stringName=吴文辉, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])])], keywords=[Keyword(id=1322923609999680071, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=1, keyword=Jiucaizi(Semen Allii Tuberosi)), Keyword(id=1322923610079371849, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=2, keyword=processing), Keyword(id=1322923610150675018, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=3, keyword=HS-GC-IMS), Keyword(id=1322923610213589579, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=4, keyword=specific odorsJiucaizi(Semen Allii Tuberosi)), Keyword(id=1322923610284892748, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=5, keyword=processing), Keyword(id=1322923610347807309, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=6, keyword=HS-GC-IMS), Keyword(id=1322923610410721870, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, orderNo=7, keyword=specific odors), Keyword(id=1322923610494607951, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, orderNo=1, keyword=韭菜子), Keyword(id=1322923610603659856, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, orderNo=2, keyword=炮制), Keyword(id=1322923610674963025, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, orderNo=3, keyword=气相色谱—离子迁移质谱), Keyword(id=1322923610742071890, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, orderNo=4, keyword=特异性气味)], refs=[Reference(id=1322923614256898663, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2002, volume=null, issue=null, pageStart=532, pageEnd=533, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=高学敏, journalName=中药学, refType=null, unstructuredReference=高学敏. 中药学[M]. 北京:中国中医药出版社,2002:532-533, articleTitle=null, refAbstract=null), Reference(id=1322923614324007528, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2021, volume=null, issue=null, pageStart=238, pageEnd=239, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=钟凌云, journalName=中药炮制学, refType=null, unstructuredReference=钟凌云. 中药炮制学[M]. 5版. 北京:中国中医药出版社,2021:238-239., articleTitle=null, refAbstract=null), Reference(id=1322923614395310698, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2015, volume=38, issue=6, pageStart=1223, pageEnd=1224, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=王雯萱, 葛发欢, 张湘东, journalName=中药材, refType=null, unstructuredReference=王雯萱,葛发欢,张湘东. 韭菜子挥发油的GC-MS分析[J]. 中药材,2015,38(6):1223-1224., articleTitle=韭菜子挥发油的GC-MS分析, refAbstract=null), Reference(id=1322923614475002475, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=39, issue=11, pageStart=121, pageEnd=128, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=赵日虹, 刘习平, 周昭丽, journalName=中药药理与临床, refType=null, unstructuredReference=赵日虹,刘习平,周昭丽,等. 韭菜子化学成分、药理作用及质量标志物(Q-Marker)的预测分析[J]. 中药药理与临床,2023,39(11):121-128., articleTitle=韭菜子化学成分、药理作用及质量标志物(Q-Marker)的预测分析, refAbstract=null), Reference(id=1322923614542111340, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=10, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=ZHU H, ZHU D Z, SUN JM, journalName=Front Nutr, refType=null, unstructuredReference=ZHU H,ZHU D Z,SUN JM. Application of GC-IMScoupled with chemometric analysis for the classification and authentication of geographical indication agricultural products and food[J]. Front Nutr,2023,10:1247695., articleTitle=Application of GC-IMScoupled with chemometric analysis for the classification and authentication of geographical indication agricultural products and food, refAbstract=null), Reference(id=1322923614605025901, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=11, issue=3, pageStart=421, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=QIAO Y N, CHEN Q Q, BI J F, journalName=Foods, refType=null, unstructuredReference=QIAO Y N,CHEN Q Q,BI J F,et al. Investigation of the volatile profile of red jujube by using GC-IMS,multivariate data analysis,and descriptive sensory analysis[J]. Foods,2022,11(3):421., articleTitle=Investigation of the volatile profile of red jujube by using GC-IMS,multivariate data analysis,and descriptive sensory analysis, refAbstract=null), Reference(id=1322923614676329070, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=28, issue=13, pageStart=4883, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=DUAN H, ZHOU Y X, WANGD D, journalName=Molecules, refType=null, unstructuredReference=DUAN H,ZHOU Y X,WANGD D,et al. Differences in volatile organic compounds in Rhizoma gastrodiae(Tian Ma)of different origins determined by HS-GC-IMS[J]. Molecules,2023,28(13):4883., articleTitle=Differences in volatile organic compounds in Rhizoma gastrodiae(Tian Ma)of different origins determined by HS-GC-IMS, refAbstract=null), Reference(id=1322923614760215151, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=28, issue=18, pageStart=6705, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=DUAN H, ZHOU SQ, GUO J H, journalName=Molecules, refType=null, unstructuredReference=DUAN H,ZHOU SQ,GUO J H,et al. HS-GC-IMSanalysis of volatile organic compounds in different varieties and harvesting times of Rhizoma gastrodiae(Tian Ma)in Yunnan Province[J]. Molecules,2023,28(18):6705., articleTitle=HS-GC-IMSanalysis of volatile organic compounds in different varieties and harvesting times of Rhizoma gastrodiae(Tian Ma)in Yunnan Province, refAbstract=null), Reference(id=1322923614877655664, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=11, issue=17, pageStart=2662, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=YU X Y, CHEN X C, LI Y T, journalName=Foods, refType=null, unstructuredReference=YU X Y,CHEN X C,LI Y T,et al. Effect of drying methods on volatile compounds of Citrus reticulata ponkan and Chachi peels as characterized by GC-MS and GC-IMS[J]. Foods,2022,11(17):2662., articleTitle=Effect of drying methods on volatile compounds of Citrus reticulata ponkan and Chachi peels as characterized by GC-MS and GC-IMS, refAbstract=null), Reference(id=1322923614948958833, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2021, volume=27, issue=10, pageStart=85, pageEnd=92, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=冯靖雯, 郭小红, 张砚, journalName=中国实验方剂学杂志, refType=null, unstructuredReference=冯靖雯,郭小红,张砚,等. 不同花期闹羊花中挥发性成分的GC-IMS分析[J]. 中国实验方剂学杂志,2021,27(10):85-92., articleTitle=不同花期闹羊花中挥发性成分的GC-IMS分析, refAbstract=null), Reference(id=1322923615016067698, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=14, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=WANG M, LI X, DING H Y, journalName=Front Plant Sci, refType=null, unstructuredReference=WANG M,LI X,DING H Y,et al. Comparison of the volatile organic compounds in Citrus reticulata‘Chachi’peel with different drying methods using E-nose,GC-IMSand HS-SPME-GCMS[J]. Front Plant Sci,2023,14:1169321., articleTitle=Comparison of the volatile organic compounds in Citrus reticulata‘Chachi’peel with different drying methods using E-nose,GC-IMSand HS-SPME-GCMS, refAbstract=null), Reference(id=1322923615095759475, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=57, issue=16, pageStart=1329, pageEnd=1336, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=宋艺君, 郭涛, 高阳丽, journalName=中国药学杂志, refType=null, unstructuredReference=宋艺君,郭涛,高阳丽,等. GC-IMS法比较黄精不同炮制品特征气味物质差异[J]. 中国药学杂志,2022,57(16):1329-1336., articleTitle=GC-IMS法比较黄精不同炮制品特征气味物质差异, refAbstract=null), Reference(id=1322923615292891764, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=106, issue=2, pageStart=445, pageEnd=456, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=MA L K, LUO Y Y, CHEN B L, journalName=J AOACInt, refType=null, unstructuredReference=MA L K,LUO Y Y,CHEN B L,et al. Determination of characteristic volatile component fingerprint of Peucedanum praeruptorum dunn at different harvest periods based on HS-GC-IMS[J]. J AOACInt,2023,106(2):445-456., articleTitle=Determination of characteristic volatile component fingerprint of Peucedanum praeruptorum dunn at different harvest periods based on HS-GC-IMS, refAbstract=null), Reference(id=1322923616979001974, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2021, volume=35, issue=3, pageStart=47, pageEnd=50, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=吴文辉, 刘霞, 郭小红, journalName=现代中药研究与实践, refType=null, unstructuredReference=吴文辉,刘霞,郭小红,等. 加热炒制对韭菜子出膏率、粉碎率及6种核苷类物质含量动态影响的研究[J]. 现代中药研究与实践,2021,35(3):47-50., articleTitle=加热炒制对韭菜子出膏率、粉碎率及6种核苷类物质含量动态影响的研究, refAbstract=null), Reference(id=1322923617088053879, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=419, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=WANG P P, KAN Q X, YANG L X, journalName=Food Chem, refType=null, unstructuredReference=WANG P P,KAN Q X,YANG L X,et al. Characterization of the key aroma compounds in soy sauce by gas chromatography-mass spectrometry-olfactometry,headspace-gas chromatography-ion mobility spectrometry,odor activity value,and aroma recombination and omission analysis[J]. Food Chem,2023,419:135995., articleTitle=Characterization of the key aroma compounds in soy sauce by gas chromatography-mass spectrometry-olfactometry,headspace-gas chromatography-ion mobility spectrometry,odor activity value,and aroma recombination and omission analysis, refAbstract=null), Reference(id=1322923617406820985, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=18, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=YU H Y, LIQW, GUOW, journalName=Food Chem X, refType=null, unstructuredReference=YU H Y,LIQW,GUOW,et al. Dynamic analysis of volatile metabolites and microbial community and their correlations during the fermentation process of traditional Huangjiu(Chinese rice wine)produced around Winter Solstice[J]. Food Chem X,2023,18:100620., articleTitle=Dynamic analysis of volatile metabolites and microbial community and their correlations during the fermentation process of traditional Huangjiu(Chinese rice wine)produced around Winter Solstice, refAbstract=null), Reference(id=1322923617515872890, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=171, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=SUN D D, LI W X, LUO L X, journalName=Food Res Int, refType=null, unstructuredReference=SUN D D,LI W X,LUO L X. Deciphering the brewing process of Cantonese-style rice vinegar:main flavors,key physicochemical factors,and important microorganisms[J]. Food Res Int,2023,171:113068., articleTitle=Deciphering the brewing process of Cantonese-style rice vinegar:main flavors,key physicochemical factors,and important microorganisms, refAbstract=null), Reference(id=1322923617864000123, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=13, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=MITRA S, DASR, EMRAN T B, journalName=Front Pharmacol, refType=null, unstructuredReference=MITRA S,DASR,EMRAN T B,et al. Diallyl disulfide:a bioactive garlic compound with anticancer potential[J]. Front Pharmacol,2022,13:943967., articleTitle=Diallyl disulfide:a bioactive garlic compound with anticancer potential, refAbstract=null), Reference(id=1322923617939497596, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=14, issue=5, pageStart=308, pageEnd=316, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=黎晶晶, 余天, 袁娟丽, journalName=食品安全质量检测学报, refType=null, unstructuredReference=黎晶晶,余天,袁娟丽,等. 大蒜素分解产物二烯丙基二硫对小鼠急性肝损伤的保护作用[J]. 食品安全质量检测学报,2023,14(5):308-316., articleTitle=大蒜素分解产物二烯丙基二硫对小鼠急性肝损伤的保护作用, refAbstract=null), Reference(id=1322923618233098877, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=刘诗旋, journalName=null, refType=null, unstructuredReference=刘诗旋. 二烯丙基二硫通过调控“肠-肝轴”和维持肝细胞脂肪代谢稳态减轻酒精性肝病[D]. 济南:山东大学,2023., articleTitle=二烯丙基二硫通过调控“肠-肝轴”和维持肝细胞脂肪代谢稳态减轻酒精性肝病, refAbstract=null), Reference(id=1322923618312790654, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=窦佳艺, journalName=null, refType=null, unstructuredReference=窦佳艺. 二烯丙基二硫介导FXR——YAP1信号交互改善肺纤维化的研究[D]. 延吉:延边大学,2022., articleTitle=二烯丙基二硫介导FXR——YAP1信号交互改善肺纤维化的研究, refAbstract=null), Reference(id=1322923618375705215, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2019, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=王琼, journalName=null, refType=null, unstructuredReference=王琼. 二烯丙基二硫对高脂血症大鼠的降血脂效果和机制研究[D]. 济南:山东大学,2019., articleTitle=二烯丙基二硫对高脂血症大鼠的降血脂效果和机制研究, refAbstract=null), Reference(id=1322923618639946368, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2021, volume=10, issue=11, pageStart=1844, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=HERRERA-CALDERON O, CHACALTANA-RAMOS L J, HUAYANCA-GUTIÉRREZ I C, journalName=Antioxidants, refType=null, unstructuredReference=HERRERA-CALDERON O,CHACALTANA-RAMOS L J,HUAYANCA-GUTIÉRREZ I C,et al. Chemical constituents,in vitro antioxidant activity and in silico study on NADPH oxidase of Allium sativum L. (garlic)essential oil[J]. Antioxidants,2021,10(11):1844., articleTitle=Chemical constituents,in vitro antioxidant activity and in silico study on NADPH oxidase of Allium sativum L. (garlic)essential oil, refAbstract=null), Reference(id=1322923618748998273, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2019, volume=32, issue=8, pageStart=1205, pageEnd=1210, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=WONGMANEEPRATIP W, JOM K N, VANGNAI K, journalName=Asian-Australas J Anim Sci, refType=null, unstructuredReference=WONGMANEEPRATIP W,JOM K N,VANGNAI K. Inhibitory effects of dietary antioxidants on the formation of carcinogenic polycyclic aromatic hydrocarbons in grilled pork[J]. Asian-Australas J Anim Sci,2019,32(8):1205-1210., articleTitle=Inhibitory effects of dietary antioxidants on the formation of carcinogenic polycyclic aromatic hydrocarbons in grilled pork, refAbstract=null), Reference(id=1322923619050988162, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2020, volume=2020, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=ZHANG H X, SHANG C, TIAN Z, journalName=Mediators Inflamm, refType=null, unstructuredReference=ZHANG H X,SHANG C,TIAN Z,et al. Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice[J]. Mediators Inflamm,2020,2020:8508906., articleTitle=Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice, refAbstract=null), Reference(id=1322923619155845763, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2019, volume=34, issue=1, pageStart=319, pageEnd=329, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=GAO W Q, WANGW, LIUG, journalName=Metab Brain Dis, refType=null, unstructuredReference=GAO W Q,WANGW,LIUG,et al. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome[J]. Metab Brain Dis,2019,34(1):319-329., articleTitle=Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome, refAbstract=null), Reference(id=1322923619483001476, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2022, volume=11, issue=11, pageStart=1631, pageEnd=null, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=WU X Y, FAUCONNIER M L, BI J F, journalName=Foods, refType=null, unstructuredReference=WU X Y,FAUCONNIER M L,BI J F. Characterization and discrimination of apples by flash GCE-nose:geographical regionsand botanical origins studies in China[J]. Foods,2022,11(11):1631., articleTitle=Characterization and discrimination of apples by flash GCE-nose:geographical regionsand botanical origins studies in China, refAbstract=null), Reference(id=1322923619566887557, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=14, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=SHEN M, XIE Q Y, ZHANG R Z, journalName=Front Pharmacol, refType=null, unstructuredReference=SHEN M,XIE Q Y,ZHANG R Z,et al. Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes[J]. Front Pharmacol,2023,14:1175021., articleTitle=Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes, refAbstract=null), Reference(id=1322923619898237574, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=62, issue=5, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=CHEN K Y, CHENG C J, CHEN Y J, journalName=Int J Antimicrob Agents, refType=null, unstructuredReference=CHEN K Y,CHENG C J,CHEN Y J,et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. Int J Antimicrob Agents,2023,62(5):106963., articleTitle=Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice, refAbstract=null), Reference(id=1322923621622096520, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, doi=null, pmid=null, pmcid=null, year=2023, volume=1271, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=AZORÍN C, LÓPEZ-JUAN A L, APARISI F, journalName=Anal Chim Acta, refType=null, unstructuredReference=AZORÍN C,LÓPEZ-JUAN A L,APARISI F,et al. Determination of hexanal and heptanal in saliva samples by an adapted magnetic headspace adsorptive microextraction for diagnosis of lung cancer[J]. Anal Chim Acta,2023,1271:341435., articleTitle=Determination of hexanal and heptanal in saliva samples by an adapted magnetic headspace adsorptive microextraction for diagnosis of lung cancer, refAbstract=null)], funds=[Fund(id=1322923613967491684, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, awardId=国中医药科技中药便函〔2022〕59号, language=CN, fundingSource=国家中医药管理局中药炮制技术传承基地建设项目(国中医药科技中药便函〔2022〕59号), fundOrder=null, country=null), Fund(id=1322923614034600549, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, awardId=CSTC2018JCYJAX0017, language=CN, fundingSource=重庆市自然科学基金项目(CSTC2018JCYJAX0017), fundOrder=null, country=null), Fund(id=1322923614097515110, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, awardId=渝中医〔2018〕43号, language=CN, fundingSource=重庆市卫健委“十三五”市级中医药重点学科项目(渝中医〔2018〕43号), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])], figs=[ArticleFig(id=1322923610872095315, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=rWFmsGfGyf5/6SuKGKvOxg==, figureFileBig=ctNNh0qYqPy1x+rmkv/yjg==, tableContent=null), ArticleFig(id=1322923612574982741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图1, caption=韭菜子不同炮制方法下样品气相色谱离子迁移谱谱图, figureFileSmall=rWFmsGfGyf5/6SuKGKvOxg==, figureFileBig=ctNNh0qYqPy1x+rmkv/yjg==, tableContent=null), ArticleFig(id=1322923612814058070, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=+0q7jPbur8XJpuVkz1660A==, figureFileBig=PM+7zFcmSHbEk0AGIUfyZQ==, tableContent=null), ArticleFig(id=1322923612897944151, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图2, caption=韭菜子不同炮制方法下样品气相色谱离子迁移谱差异图(以净制韭菜籽谱图为背景参照), figureFileSmall=+0q7jPbur8XJpuVkz1660A==, figureFileBig=PM+7zFcmSHbEk0AGIUfyZQ==, tableContent=null), ArticleFig(id=1322923612990218840, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=2eQet3FLbZymX91Sym+V6g==, figureFileBig=DVOeUcclbb7M1x17ljeVAw==, tableContent=null), ArticleFig(id=1322923613078299225, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图3, caption=不同炮制方法韭菜籽的PCA(主成分分析)图, figureFileSmall=2eQet3FLbZymX91Sym+V6g==, figureFileBig=DVOeUcclbb7M1x17ljeVAw==, tableContent=null), ArticleFig(id=1322923613153796698, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=vAHm0motdNB1BBdXTAWbnw==, figureFileBig=AcN4Wc+O9zNp2WYfJb2LYw==, tableContent=null), ArticleFig(id=1322923613216711259, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图4, caption=不同炮制方法韭菜籽的“最邻近”分析图, figureFileSmall=vAHm0motdNB1BBdXTAWbnw==, figureFileBig=AcN4Wc+O9zNp2WYfJb2LYw==, tableContent=null), ArticleFig(id=1322923613288014428, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=oWi5cPvpGnvWWpOqihUUow==, figureFileBig=mPgGrfhJGmcnceOMF3K7cQ==, tableContent=null), ArticleFig(id=1322923613371900509, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图5, caption=生品及6种炮制工艺韭菜子的挥发性物质的Gallery Plot图(指纹图谱), figureFileSmall=oWi5cPvpGnvWWpOqihUUow==, figureFileBig=mPgGrfhJGmcnceOMF3K7cQ==, tableContent=null), ArticleFig(id=1322923613439009374, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=jOMSjfOGpAxYaUbEWMPI0Q==, figureFileBig=owLeXCvem+twdBd4AEH6+Q==, tableContent=null), ArticleFig(id=1322923613514506847, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=图6, caption=韭菜子不同炮制方法特异性气味物质相对峰强度(面积), figureFileSmall=jOMSjfOGpAxYaUbEWMPI0Q==, figureFileBig=owLeXCvem+twdBd4AEH6+Q==, tableContent=null), ArticleFig(id=1322923613598392928, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
编号名称炮制方法
P1生品取原药材,除去杂质
P2酒炙取净韭菜子,用适量黄酒拌匀,闷润,待酒被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用黄酒10 kg
P3盐炙取净韭菜子,用盐水拌匀,待盐水被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用食盐2 kg
P4醋炙取净韭菜子,用适量米醋拌匀,闷润,待米醋被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用米醋20 kg
P5清炒取净韭菜子,置炒制容器内,用文火加热炒至有香气,取出,放凉
P6盐酒共炙取净韭菜子,用适量黄酒和盐水拌匀,闷润,待盐酒水被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用黄酒10 kg,食盐2 kg
P7蒸熟取净韭菜子,加适量清水拌匀,润透,置蒸制容器内,蒸熟,干燥
), ArticleFig(id=1322923613673890401, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=表1, caption=

韭菜籽样品与炮制信息

, figureFileSmall=null, figureFileBig=null, tableContent=
编号名称炮制方法
P1生品取原药材,除去杂质
P2酒炙取净韭菜子,用适量黄酒拌匀,闷润,待酒被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用黄酒10 kg
P3盐炙取净韭菜子,用盐水拌匀,待盐水被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用食盐2 kg
P4醋炙取净韭菜子,用适量米醋拌匀,闷润,待米醋被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用米醋20 kg
P5清炒取净韭菜子,置炒制容器内,用文火加热炒至有香气,取出,放凉
P6盐酒共炙取净韭菜子,用适量黄酒和盐水拌匀,闷润,待盐酒水被吸尽后,置炒制容器内,用文火炒干。韭菜子每100 kg用黄酒10 kg,食盐2 kg
P7蒸熟取净韭菜子,加适量清水拌匀,润透,置蒸制容器内,蒸熟,干燥
), ArticleFig(id=1322923613740999266, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=EN, label=null, caption=null, figureFileSmall=null, figureFileBig=null, tableContent=
序号化合物分子式相对分子质量保留指数保留时间迁移时间峰强度(面积)平均值(n=3)
生品酒炙盐炙醋炙清炒盐酒共蒸
1香叶醇C10H18O154.31 250.5704.8661.233 74259.02163.55185.12252.96154.91153.11190.02
21-羟基-2-丙酮C3H6O274.1701.0163.3141.043 03870.47327.17310.64272.47220.40271.21219.62
31-戊醇C5H12O88.1768.2191.3451.517 24525.15312.26212.91332.09243.81288.10241.29
42-甲基丙醇C4H10O74.1636.2143.8931.364 77902.82420.65109.29302.24111.35278.98233.29
5二烯丙基硫醚C6H10S114.2854.2236.0241.119 591 288.12542.79441.68319.26479.71393.73253.40
6甲基-3-丁烯-1-醇C5H10O86.1729.8175.3341.497 02563.23286.87129.23183.28177.85258.7197.92
7乙醇C2H6O46.1466.597.7231.046 163 727.031 241.111 475.221 725.201 466.20929.561 424.24
8丙酸C3H6O274.1703.0164.1581.265 45331.06149.10158.40156.92200.70129.34118.71
92-乙酰呋喃C6H6O2110.1908.0270.2081.111 37283.25120.17110.6373.29156.56109.0074.58
102,5-二甲基呋喃C6H8O96.1714.0168.7661.030 46327.66244.61262.65238.85321.32193.68138.62
11乙酸乙酯C4H8O288.1610.7136.9501.335 635 306.463 632.552 392.634 659.181 942.713 804.322 650.78
12二烯丙基二硫醚C6H10S2146.31 071.7452.4811.197 263 298.432 663.702 636.422 566.052 647.352 671.312 597.97
132-戊基呋喃C9H14O138.2994.7344.8871.253 19645.01446.58453.19441.20411.74522.74391.42
14己酸MC6H12O2116.2994.0344.2821.297 51305.52222.33237.68214.98196.80239.20293.01
15己酸乙酯C8H16O2144.21 002.2354.4001.342 76162.28114.7492.7366.47109.38126.3673.74
162-丙酮C3H6O58.1507.8108.9721.114 972 896.503 005.403 635.253 797.433 387.613 036.494 334.47
17乙酸戊酯C7H14O2130.2913.2274.7041.315 00156.47226.18219.36210.21195.27221.80208.03
18二烯丙基二硫醚C6H10S2146.31 073.0454.3011.637 634 951.716 346.137 692.376 905.254 634.186 465.936 298.83
19丁酸戊酯C9H18O2158.21 072.7453.9371.400 041 663.801 947.812 254.372022.071 497.891 968.691 861.56
20苯甲酸甲酯C8H8O2136.11 097.7489.2191.205 84521.12519.43571.13545.30440.69566.58562.33
21异丁香酚C10H12O2164.21 468.51 012.4111.288 54417.23918.601 350.931 219.21586.511 000.72955.24
22(E)-2-壬烯醛C9H16O140.21 142.8552.8651.405 1640.34227.44275.28232.12132.52245.44150.44
232-乙酰吡嗪C6H6N2O122.1980.2332.3681.537 4336.45437.47603.68439.38312.66507.37419.44
242-羟基-3-甲基-2-环戊烯-1-酮C6H8O2112.11 016.1374.1471.142 96114.97258.10320.88337.93160.20254.37278.34
25顺-3-己烯醇C6H12O100.2890.0255.4221.510 44211.29313.39399.52522.39319.65331.01560.45
262-戊酮C5H10O86.1691.5159.3801.371 0396.37211.97207.18184.40173.68234.90272.33
27己酸C6H12O2116.2994.6344.7711.644 16339.18581.10512.09546.89285.93466.51550.03
282-甲酰基-5-甲基噻吩C6H6OS126.21 141.3550.7871.170 18382.461 213.671 347.791957.12874.621 336.812 073.72
293-甲基丁醛C5H10O86.1651.9148.1631.409 261 052.001 815.261 429.572 274.361 273.841 482.121 964.19
303-辛酮C8H16O128.21 002.7355.1451.714 40133.04212.16178.87235.6897.55241.37264.17
31甲硫醇C4H10OS106.2984.2335.7951.469 9858.52484.22317.40447.39219.32314.78335.26
32丁醛C4H8O72.1608.5136.3651.289 28585.111 456.061 378.071 418.631 275.651 502.711 794.61
332-环己烯-1-酮C6H8O96.1920.9281.3261.111 59751.112 298.581 889.292 057.962 617.152 020.701 572.48
34苯甲醛C7H6O106.1959.0314.1091.147 04223.23311.99228.07319.17257.07212.13245.55
35α-水芹烯C10H16136.2980.5332.6951.214 69118.43307.83382.45336.20319.80327.65337.34
36二甲基三硫醚C2H6S3126.3964.8319.1491.304 3426.24110.43178.62123.83142.41170.67138.71
372-庚酮C7H14O114.2888.9254.8331.633 87348.50875.71947.65889.90761.381 191.17983.09
382-丁酮C4H8O72.1588.6130.9271.242 761 108.352 262.712 142.132 053.942 117.932 279.343 704.50
39二甲基二硫醚C2H6S294.2746.2182.1991.141 7432.6657.88132.0492.96127.15122.12138.70
40(E)-2-辛烯醛C8H14O126.21 056.2430.6491.332 4590.50362.62286.65237.09303.91269.52164.53
41己醛C6H12O100.2794.1203.4141.561 83173.50377.01378.6466.12444.45358.2673.62
422-羟基丙酸乙酯C5H10O3118.1811.3212.7681.537 58276.361 463.04221.30123.83109.161 539.9844.17
43β-罗勒烯C10H16136.21039.0406.4081.245 9965.77395.70136.49221.40175.00211.50144.77
44顺式玫瑰醚C10H18O154.31108.0503.7951.372 1446.91255.72129.62210.4879.58111.54116.41
45戊醛C5H10O86.1701.8163.6821.422 4675.0791.98137.15175.34129.00119.37134.41
463-羟基-2-丁酮C4H8O288.1716.2169.6501.330 5981.23320.62244.66447.05139.38383.121 143.66
472,3-丁二醇C4H10O290.1791.3201.9131.369 88314.49406.55286.053 016.51303.06298.083 102.77
48糠醇C5H6O298.1880.8250.4201.364 91132.18105.89147.63377.69183.26118.62445.60
49丁内酯C4H6O286.1903.5266.3351.301 379.2672.91106.50133.4686.4694.45166.67
50芳樟醇C10H18O154.31 089.3477.3081.218 59176.76232.33260.37182.87186.73262.54468.88
512-丙醇C3H8O60.1516.0111.1991.090 25582.81867.411 598.30934.641 732.671 208.11860.59
52乙酸C2H4O260.1584.3129.7831.153 50292.23722.88923.98735.29991.04782.35466.66
53醋酸丙酯C5H10O2102.1715.1169.1881.159 75546.291 302.071 721.701 032.921 813.571 501.131 096.40
54辛醇C8H18O130.21 055.7429.9911.458 55162.65221.67225.30203.31418.75251.20235.55
), ArticleFig(id=1322923613845856867, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, language=CN, label=表2, caption=

韭菜籽及其炮制品挥发性有机物定性分析结果

, figureFileSmall=null, figureFileBig=null, tableContent=
序号化合物分子式相对分子质量保留指数保留时间迁移时间峰强度(面积)平均值(n=3)
生品酒炙盐炙醋炙清炒盐酒共蒸
1香叶醇C10H18O154.31 250.5704.8661.233 74259.02163.55185.12252.96154.91153.11190.02
21-羟基-2-丙酮C3H6O274.1701.0163.3141.043 03870.47327.17310.64272.47220.40271.21219.62
31-戊醇C5H12O88.1768.2191.3451.517 24525.15312.26212.91332.09243.81288.10241.29
42-甲基丙醇C4H10O74.1636.2143.8931.364 77902.82420.65109.29302.24111.35278.98233.29
5二烯丙基硫醚C6H10S114.2854.2236.0241.119 591 288.12542.79441.68319.26479.71393.73253.40
6甲基-3-丁烯-1-醇C5H10O86.1729.8175.3341.497 02563.23286.87129.23183.28177.85258.7197.92
7乙醇C2H6O46.1466.597.7231.046 163 727.031 241.111 475.221 725.201 466.20929.561 424.24
8丙酸C3H6O274.1703.0164.1581.265 45331.06149.10158.40156.92200.70129.34118.71
92-乙酰呋喃C6H6O2110.1908.0270.2081.111 37283.25120.17110.6373.29156.56109.0074.58
102,5-二甲基呋喃C6H8O96.1714.0168.7661.030 46327.66244.61262.65238.85321.32193.68138.62
11乙酸乙酯C4H8O288.1610.7136.9501.335 635 306.463 632.552 392.634 659.181 942.713 804.322 650.78
12二烯丙基二硫醚C6H10S2146.31 071.7452.4811.197 263 298.432 663.702 636.422 566.052 647.352 671.312 597.97
132-戊基呋喃C9H14O138.2994.7344.8871.253 19645.01446.58453.19441.20411.74522.74391.42
14己酸MC6H12O2116.2994.0344.2821.297 51305.52222.33237.68214.98196.80239.20293.01
15己酸乙酯C8H16O2144.21 002.2354.4001.342 76162.28114.7492.7366.47109.38126.3673.74
162-丙酮C3H6O58.1507.8108.9721.114 972 896.503 005.403 635.253 797.433 387.613 036.494 334.47
17乙酸戊酯C7H14O2130.2913.2274.7041.315 00156.47226.18219.36210.21195.27221.80208.03
18二烯丙基二硫醚C6H10S2146.31 073.0454.3011.637 634 951.716 346.137 692.376 905.254 634.186 465.936 298.83
19丁酸戊酯C9H18O2158.21 072.7453.9371.400 041 663.801 947.812 254.372022.071 497.891 968.691 861.56
20苯甲酸甲酯C8H8O2136.11 097.7489.2191.205 84521.12519.43571.13545.30440.69566.58562.33
21异丁香酚C10H12O2164.21 468.51 012.4111.288 54417.23918.601 350.931 219.21586.511 000.72955.24
22(E)-2-壬烯醛C9H16O140.21 142.8552.8651.405 1640.34227.44275.28232.12132.52245.44150.44
232-乙酰吡嗪C6H6N2O122.1980.2332.3681.537 4336.45437.47603.68439.38312.66507.37419.44
242-羟基-3-甲基-2-环戊烯-1-酮C6H8O2112.11 016.1374.1471.142 96114.97258.10320.88337.93160.20254.37278.34
25顺-3-己烯醇C6H12O100.2890.0255.4221.510 44211.29313.39399.52522.39319.65331.01560.45
262-戊酮C5H10O86.1691.5159.3801.371 0396.37211.97207.18184.40173.68234.90272.33
27己酸C6H12O2116.2994.6344.7711.644 16339.18581.10512.09546.89285.93466.51550.03
282-甲酰基-5-甲基噻吩C6H6OS126.21 141.3550.7871.170 18382.461 213.671 347.791957.12874.621 336.812 073.72
293-甲基丁醛C5H10O86.1651.9148.1631.409 261 052.001 815.261 429.572 274.361 273.841 482.121 964.19
303-辛酮C8H16O128.21 002.7355.1451.714 40133.04212.16178.87235.6897.55241.37264.17
31甲硫醇C4H10OS106.2984.2335.7951.469 9858.52484.22317.40447.39219.32314.78335.26
32丁醛C4H8O72.1608.5136.3651.289 28585.111 456.061 378.071 418.631 275.651 502.711 794.61
332-环己烯-1-酮C6H8O96.1920.9281.3261.111 59751.112 298.581 889.292 057.962 617.152 020.701 572.48
34苯甲醛C7H6O106.1959.0314.1091.147 04223.23311.99228.07319.17257.07212.13245.55
35α-水芹烯C10H16136.2980.5332.6951.214 69118.43307.83382.45336.20319.80327.65337.34
36二甲基三硫醚C2H6S3126.3964.8319.1491.304 3426.24110.43178.62123.83142.41170.67138.71
372-庚酮C7H14O114.2888.9254.8331.633 87348.50875.71947.65889.90761.381 191.17983.09
382-丁酮C4H8O72.1588.6130.9271.242 761 108.352 262.712 142.132 053.942 117.932 279.343 704.50
39二甲基二硫醚C2H6S294.2746.2182.1991.141 7432.6657.88132.0492.96127.15122.12138.70
40(E)-2-辛烯醛C8H14O126.21 056.2430.6491.332 4590.50362.62286.65237.09303.91269.52164.53
41己醛C6H12O100.2794.1203.4141.561 83173.50377.01378.6466.12444.45358.2673.62
422-羟基丙酸乙酯C5H10O3118.1811.3212.7681.537 58276.361 463.04221.30123.83109.161 539.9844.17
43β-罗勒烯C10H16136.21039.0406.4081.245 9965.77395.70136.49221.40175.00211.50144.77
44顺式玫瑰醚C10H18O154.31108.0503.7951.372 1446.91255.72129.62210.4879.58111.54116.41
45戊醛C5H10O86.1701.8163.6821.422 4675.0791.98137.15175.34129.00119.37134.41
463-羟基-2-丁酮C4H8O288.1716.2169.6501.330 5981.23320.62244.66447.05139.38383.121 143.66
472,3-丁二醇C4H10O290.1791.3201.9131.369 88314.49406.55286.053 016.51303.06298.083 102.77
48糠醇C5H6O298.1880.8250.4201.364 91132.18105.89147.63377.69183.26118.62445.60
49丁内酯C4H6O286.1903.5266.3351.301 379.2672.91106.50133.4686.4694.45166.67
50芳樟醇C10H18O154.31 089.3477.3081.218 59176.76232.33260.37182.87186.73262.54468.88
512-丙醇C3H8O60.1516.0111.1991.090 25582.81867.411 598.30934.641 732.671 208.11860.59
52乙酸C2H4O260.1584.3129.7831.153 50292.23722.88923.98735.29991.04782.35466.66
53醋酸丙酯C5H10O2102.1715.1169.1881.159 75546.291 302.071 721.701 032.921 813.571 501.131 096.40
54辛醇C8H18O130.21 055.7429.9911.458 55162.65221.67225.30203.31418.75251.20235.55
)], attaches=null, journal=Journal(id=1255846881855815682, delFlag=0, nameCn=中华中医药学刊, nameEn=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1673-7717, eissn=null, cn=21-1546/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=v4T+dd+NLAnioIpGAbkcEQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Archives of Traditional Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1777346829146, updatedTime=1788949222391, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=v4T+dd+NLAnioIpGAbkcEQ==, picEn=RAy5vuC40hwJB+Y0pEARug==, jcr=null, cjcr=null, exts=[JournalExt(id=1304510846391050374, language=CN, name=中华中医药学刊, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222419, updatedTime=1788949222419, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304510846449770631, language=EN, name=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222433, updatedTime=1788949222433, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1255847919539208197, websiteList=[Website(id=1255847989868900719, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN, language=CN, createTime=1777347093312, createBy=18614031015, updateTime=1777347427646, updateBy=18614031015, name=中华中医药学刊-中文, tplId=1146099689490845704, title=中华中医药学刊, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849512594170105, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=articleTextType, value=kx, createTime=1777347456358, updateTime=1777347456358, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512564809974, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=banner, value=null, createTime=1777347456352, updateTime=1777347456352, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512631918844, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=grayFlag, value=0, createTime=1777347456367, updateTime=1777347456367, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512552227061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347456348, updateTime=1777347456348, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512657084670, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=minRunFlag, value=0, createTime=1777347456373, updateTime=1777347456373, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512589975800, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic, createTime=1777347456357, updateTime=1777347456357, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512648696061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=silenceFlag, value=0, createTime=1777347456371, updateTime=1777347456371, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512581587191, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1777347456355, updateTime=1777347456355, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512619335930, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeColor, value=null, createTime=1777347456364, updateTime=1777347456364, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512627724539, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeStyle, value=null, createTime=1777347456366, updateTime=1777347456366, creator=18614031015, updator=18614031015)]), Website(id=1255847989944398211, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN, language=EN, createTime=1777347093330, createBy=18614031015, updateTime=1777347417860, updateBy=18614031015, name=中华中医药学刊-英文, tplId=1146101810881728533, title=Chinese Archives of Traditional Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849538993119491, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=articleTextType, value=kx, createTime=1777347462652, updateTime=1777347462652, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538972147968, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=banner, value=null, createTime=1777347462647, updateTime=1777347462647, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539047645446, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=grayFlag, value=0, createTime=1777347462665, updateTime=1777347462665, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538930204927, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347462637, updateTime=1777347462637, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539064422664, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=minRunFlag, value=0, createTime=1777347462669, updateTime=1777347462669, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538988925186, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic, createTime=1777347462651, updateTime=1777347462651, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539060228359, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=silenceFlag, value=0, createTime=1777347462668, updateTime=1777347462668, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538980536577, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1777347462649, updateTime=1777347462649, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539001508100, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeColor, value=null, createTime=1777347462654, updateTime=1777347462654, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539039256837, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeStyle, value=null, createTime=1777347462663, updateTime=1777347462663, creator=18614031015, updator=18614031015)])], journalTitle=中华中医药学刊, weixinUrl=null, journalUrl=https://castjournals.cast.org.cn/zhzyyxk, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Archives of Traditional Chinese Medicine, journalPhotoCn=v4T+dd+NLAnioIpGAbkcEQ==, journalPhotoEn=RAy5vuC40hwJB+Y0pEARug==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2025.05.014, detailUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2025.05.014, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/PDF/10.13193/j.issn.1673-7717.2025.05.014, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/PDF/10.13193/j.issn.1673-7717.2025.05.014, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=1, orderTime=1746806400000, fullTextJson=null, articleText=null, reference=null)
收藏切换
韭菜子不同炮制品特异性气味的GC-IMS比较
收藏切换
PDF下载
周芃 , 郭小红 , 李杰 , 陈娟 , 赵迪加 , 吴文辉
中华中医药学刊 | 国家项目点击 2025,43(5): 61-65
收起
收藏切换
中华中医药学刊 |国家项目点击 2025 , 43 (5) : 61 -65
韭菜子不同炮制品特异性气味的GC-IMS比较
全屏
[Author(id=1322923608389067306, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608451981868, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608389067306, language=EN, stringName=Peng ZHOU, firstName=Peng, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608523285037, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608389067306, language=CN, stringName=周芃, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio={"content":"

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

"}, bioImg=null, bioContent=

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923608602976815, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608674279985, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608602976815, language=EN, stringName=Xiaohong GUO, firstName=Xiaohong, middleName=null, lastName=GUO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608741388850, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608602976815, language=CN, stringName=郭小红, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923608842052148, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923608913355318, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608842052148, language=EN, stringName=Jie LI, firstName=Jie, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923608988852791, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923608842052148, language=CN, stringName=李杰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609085321785, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923609198567995, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609085321785, language=EN, stringName=Juan CHEN, firstName=Juan, middleName=null, lastName=CHEN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609290842684, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609085321785, language=CN, stringName=陈娟, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609378923070, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322923609487974976, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609378923070, language=EN, stringName=Dijia ZHAO, firstName=Dijia, middleName=null, lastName=ZHAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609622192705, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609378923070, language=CN, stringName=赵迪加, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])]), Author(id=1322923609697690179, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=cqwuwenhui@126.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1322923609806742085, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609697690179, language=EN, stringName=Wenhui WU, firstName=Wenhui, middleName=null, lastName=WU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322923609890628166, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, authorId=1322923609697690179, language=CN, stringName=吴文辉, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=重庆市中医院,重庆 400021, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322923608305181222, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, xref=null, ext=[AuthorCompanyExt(id=1322923608313569831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China), AuthorCompanyExt(id=1322923608321958440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1322923604471587350, companyId=1322923608305181222, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=重庆市中医院,重庆 400021)])])]
周芃, 郭小红, 李杰, 陈娟, 赵迪加, 吴文辉
作者信息
  • 重庆市中医院,重庆 400021
通讯作者:
吴文辉(1986-),男,四川绵阳人,副主任中药师,博士,研究方向:中药炮制原理。E-mail:。
作者简介:

周芃(1985-),男,重庆人,主管药师,学士,研究方向:药剂学。

Comparison of Specific Odors of Different Processed Jiucaizi(Semen Allii Tuberosi)by GC-IMS
Peng ZHOU, Xiaohong GUO, Jie LI, Juan CHEN, Dijia ZHAO, Wenhui WU
Affiliations
  • Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China
出版时间: 2025-05-10 doi: 10.13193/j.issn.1673-7717.2025.05.014
文章导航
收藏切换
目的

对比分析韭菜子生品、酒炙品、盐炙品、醋炙品、清炒品、盐酒共炙品以及蒸熟品等不同炮制方法下特异性气味的差异,建立一种可从气味上区分韭菜子不同炮制品的方法,并为进一步研究韭菜子的炮制化学转化提供参考。

方法

采用气相色谱—离子迁移质谱(Gas chromatography-ion migration mass spectrometry,GC-IMS)技术对韭菜子不同炮制品的挥发性有机物进行检测,并结合VOCal、Reporter、Gallery Plot、Dynamic PCA等软件对GC-IMS谱图进行差异分析、指纹分析、动态主成分分析、相似度分析以及差异物质的定性分析。

结果

GC-IMS图谱的差异分析显示不同炮制方法下的韭菜子特异性气味成分存在显著差异,明确定性的差异物有54种。其中,香叶醇(Geraniol)、乙酰甲醇(1-hydroxy-2-propanone)、正戊醇(1-pentanol)、2-甲基丙醇(2-Methylpropanol)、烯丙基硫醚(diallyl sulfide)、3-甲基-3-丁烯-1-醇(Methyl-3-but-3-en-1-ol)、乙醇(Ethanol)、丙酸(Propanoic acid)、2-乙酰呋喃(2-acetylfuran)、2,5-二甲基呋喃(2,5-Dimethylfuran)、乙酸乙酯(ethyl acetate)、二烯丙基二硫M(Diallyl disulfide M)、正戊基呋喃(2-Pentylfuran)、己酸M(Hexanoic acid M)、己酸乙酯(Ethyl hexanoate)可作为韭菜子生品的特异性气味的特征挥发物质;2-羟基丙酸乙酯(ethyl 2-hydroxypropanoate)和β-罗勒烯(beta-Ocimene)可作为酒炙或盐酒共炙等辅料为酒的韭菜子炮制品的特异性气味的特征挥发物质;戊醛(pentanal)可作为醋炙韭菜子的特异性气味的特征挥发物质;呋喃甲醇(Furfuryl alcohol)、3-羟基-2-丁酮(3-hydroxy-2-butanone)、丁内酯(Butyrolactone)和芳樟醇(Linalool)可作为蒸熟韭菜子的特异性气味的特征挥发物质;辛醇(Octanol)可作为清炒韭菜子的特异性气味的特征挥发物质。PCA结果显示各组样品分离度良好,且具有相同辅料的样品相似度更大。

结论

韭菜子经不同方法炮制后其特异性气味成分存在明显差异,GC-IMS技术可作为一种区别韭菜子不同炮制品特异性气味的方法,并为进一步研究韭菜子的炮制转化提供参考。

韭菜子  /  炮制  /  气相色谱—离子迁移质谱  /  特异性气味
Objective

To compare and analyze the differences of the special odors of Jiucaizi(Semen Allii Tuberosi)under different processing methods,such as raw products,stir-fried products with wine,stir-fried products with salt,stir-fried products with vinegar,stir-fried products with nothing,stir-fried products with salt and wine,steamed products. And to establish a method for distinguishing different processed products of Jiucaizi(Semen Allii Tuberosi)from their odors to provide a reference for further study of chemical transformation of Jiucaizi(Semen Allii Tuberosi).

Methods

GC-IMStechnology was used to detect volatile organic compounds in different processed products of Jiucaizi(Semen Allii Tuberosi)through the instrument combined with VOCal and plug-in Reporter,Gallery Plot and Dynamic PCA analysis from different angles including differential analysis,fingerprint analysis,dynamic principal component analysis,similarity analysis and qualitative analysis of differential substances.

Result

The difference analysis of GC-IMSshowed that there were significant differences in the specific odor components of Jiucaizi(Semen Allii Tuberosi)under different processing methods. About 54 compounds had been identified. Among them,geraniol,1-hydroxy-2-propanone,1-pentanol,2-methylpropanol,diallyl sulfide,Methyl-3-but-3-en-1-ol,ehanol,propanoic acid,2-acetylfuran,5-dimethylfuran,ethyl acetate,diallyl disulfide M,2-pentylfuran,hexanoic acid M and ethyl hexanoate can be used as the characteristic volatiles of the special odors of raw products. Ethyl 2-hydroxypropanoate and beta-Ocimene can be used as the characteristic volatiles of the special odors of Jiucaizi(Semen Allii Tuberosi)processed with wine or salt and wine;pentanal can be used as the characteristic volatiles of the special odors of stir-fried products with vinegar;3-hydroxy-2-butanone,butyrolactone and linalool could be used as the characteristic volatiles of steamed Jiucaizi(Semen Allii Tuberosi),and octanol could be used as the characteristic volatiles of stir-fried products with nothing. The PCA results showed that the separation of the samples was good,and the similarity of the samples with the same excipients was greater.

Conclusion

There are obvious differences in the specific odor components of Jiucaizi(Semen Allii Tuberosi)processed by different methods. GC-IMStechnology can be used as a method to distinguish the specific odor of different processed products of Jiucaizi(Semen Allii Tuberosi). It also provides reference for further study on the processing and transformation of Jiucaizi(Semen Allii Tuberosi).

Jiucaizi(Semen Allii Tuberosi)  /  processing  /  HS-GC-IMS  /  specific odorsJiucaizi(Semen Allii Tuberosi)  /  processing  /  HS-GC-IMS  /  specific odors
周芃, 郭小红, 李杰, 陈娟, 赵迪加, 吴文辉. 韭菜子不同炮制品特异性气味的GC-IMS比较. 中华中医药学刊, 2025 , 43 (5) : 61 -65 . DOI: 10.13193/j.issn.1673-7717.2025.05.014
Peng ZHOU, Xiaohong GUO, Jie LI, Juan CHEN, Dijia ZHAO, Wenhui WU. Comparison of Specific Odors of Different Processed Jiucaizi(Semen Allii Tuberosi)by GC-IMS[J]. Chinese Archives of Traditional Chinese Medicine, 2025 , 43 (5) : 61 -65 . DOI: 10.13193/j.issn.1673-7717.2025.05.014
韭菜子是我国原产蔬菜韭菜Allium tuberosum Rottl.exSpreng.的干燥成熟种子,其味辛、甘,性温,归肝经、肾经,具有温补肝肾、壮阳固精的功能[1]。一直以来,韭菜子都被誉为中国古代民间“四大壮阳药”之一,为增强其临床疗效,历代医家有盐炙、酒浸、熬、酒浸曝干微炒、炒、醋煮炒香、汤浸、枣酒制、酒浸炒、焙、酒煮、蒸熟炒用和醋炒等多种炮制方法的应用,认为:炒后性温气香,温胃止呕,对胃寒呕吐具有一定疗效;酒炙能增强韭菜子温肾助阳作用;盐炙引药入肾经等[2]。
韭菜子及其所属的葱属植物均有一股强烈的辛辣性气味。现代研究证明:韭菜子含有大量挥发油,且大多为二硫、三硫化物、醛类、醇类以及酮类化合物,是其主要的药效物质之一,也是其辛辣性气味来源[3]。有学者发现,诸如韭菜子类的葱属植物挥发油会因产地、部位、生长周期、提取方法、分析方法的不同,呈现明显的差异[4]。而炮制方法的不同是否对韭菜子挥发油或辛辣气味有影响尚待系统研究。
气相-离子迁移谱技术(Gas chromatography-ion migration mass spectrometry,GC-IMS)是衡量挥发性有机气体的快速可靠分析手段,较电子鼻,气相色谱法(Gas chromatography,GC)嗅闻分析,气相色谱-质谱联用仪(Gas chromatography-Mass spectrometer,GC-MS)等中药领域常用挥发性成分检测技术更加快速、更加灵敏[5]。目前,该技术正在中药基原[6]、产地[7]、种植周期[8]及炮制加工[9]等领域中广泛应用。因此,本文采用该项技术对不同炮制条件下韭菜子特异性气味成分差异进行系统分析,为进一步研究韭菜子的炮制化学转化提供参考。
FlavourSpec®气相色谱-离子迁移谱联用仪(山东海能科学仪器有限公司);电热鼓风干燥箱(上海一恒科学仪器有限公司);New Classic MF MS205DU万分之一电子天平(瑞士梅特勒-托利多公司),SL-100型小型高速万能粉碎机(浙江省永康市松青五金厂)。
韭菜子购于重庆桐君阁股份有限公司(批号:20200706),经重庆市中医研究院制剂研究所杨敏主任中药师鉴定为百合科植物韭菜Allium tuberosum Rottl.的种子,韭菜子不同炮制样品按照《中华人民共和国药典》2020年版“四部”0213炮制通则炮制。详细信息见表1。
气相色谱条件[10-11]:E1漂移气体积流量0~30 min,150 mL/min;E2气相载气体积流量0~2 min,2 mL/min;2~20 min,2~100 mL/min;20~30 min,100 mL/min。
离子迁移谱条件[12-13]:色谱柱为FS-SE-54-CB-1(15 m×0.53 mm,1μm),分析时间30 min,柱温60℃,载气/漂移气N2,IMS温度45℃。自动顶空进样单元:孵化温度80℃,孵化时间20 min,进样体积500μL,进样针温度85℃,孵化转速500 r/min。
精密称取1 g韭菜籽粉末(过5号筛),直接置于20 mL顶空进样瓶中,80℃孵育20 min后按“2.1”项方法进行测定,每个样品平行3次。
使用仪器自带的分析软件VOCal及其内置的NIST数据库和IMS数据库对特征气味物质进行定性分析;运用Reporter插件直接对比样品之间的谱图差异,并且采用Gallery Plot插件进行指纹图谱对比,直观且定量地比较不同样品之间的挥发性物质差异;采用Dynamic PCA进行主成分分析(PCA)。
使用Reporter插件生成不同炮制方法下韭菜子挥发性化合物的GC-IMS二维俯视图,可直观对比韭菜子不同炮制方法下样品的挥发性物质差异。蓝色为背景,离子迁移时间为横坐标,气相色谱的保留时间为纵坐标。横坐标1.0处红色竖线为RIP峰,其1.0处红色竖线为经归一化处理后的反应离子峰(RIP峰),RIP峰两侧的每1个点代表1种挥发性有机物,颜色示意有机物浓度,白色表示浓度较低,红色表示浓度较高,颜色越深表示浓度越大。可看出,韭菜子经不同方法炮制后挥发性有机物发生了变化。结果见插页ⅩⅧ图1。
为更加明显比较不同样品图谱的差异,进一步采用差异对比模式,选取净制品谱图为参比,其他谱图依次对参比进行扣除,与参比浓度一样则扣减为白色背景,高于参比浓度则为红色且红色越深则超出越多,低于参比浓度则为蓝色且低得越多蓝色越深。可看出,不同炮制方法下韭菜子挥发性有机物含量存在明显差异,特别是酒炙、盐炙、醋炙、盐酒共炙、蒸熟较净制挥发性有机物增加明显。结果见插页ⅩⅧ图2。
为进一步确定不同炮制方法韭菜子样品是否有交集。将GC-IMS所测不同方法炮制韭菜子样品数据导入Dynamic PCA插件进行动态主成分和最邻近分析。可见,不同炮制方法下韭菜子各样品分类良好,说明存在差异,且各炮制方法对韭菜子的影响不同。结果见插页ⅩⅨ图3、插页ⅩⅨ图4。
为更加全面分析不同炮制样品间挥发性有机物的组分差异,采用Galleryplot插件提取GC-IMS谱图中全部待分析峰形成指纹图谱,图中每一行代表一个样品中选取的全部信号峰,每一列代表同一挥发性有机物在不同样品中的信号峰,每个样品平行测定3次。同理,红色越深则代表该物质浓度越高,反之则浓度越低。从韭菜籽及其炮制品中共分析检测出100种具有差异的特异性气味成分,通过软件内置的NIST 2014和IMS数据库鉴定出了54个化合物。结果见插页ⅩⅩ图5。
通过指纹图谱可以看出,不同炮制方法韭菜子样品挥发性物质既有共同区域,也有各自的特征峰区域:(1)生品韭菜子样品(P1)的挥发性物质种类特征区域与其他样品相差十分明显,主要体现在A框所示物质香叶醇、乙酰甲醇、正戊醇、2-甲基丙醇、丙烯基硫醚、3-甲基-3-丁烯-1-醇、乙醇、丙酸、2-乙酰呋喃、2,5二甲基呋喃、乙酸乙酯ethyl acetate、二烯丙基二硫M、正戊基呋喃、己酸M、己酸乙酯以及未知化合物2、23、1、16、18、26、21、3和10的浓度远高于各炮制样品;B框所示物质丁醛、(E)-2-辛烯醛、苯甲醛、2-丁酮、2-庚酮、2-环己烯-1-酮、二甲基三硫醚、二甲基二硫醚、α-水芹烯以及未知化合物28、9、37的浓度远低于各炮制样品,可作为韭菜子生品特征性挥发物质。(2)清炒韭菜子样品(P5)与其他炮制样品区别主要体现在C框所示物质乙酸戊酯、二烯丙基二硫醚D、丁酸戊酯、苯甲酸甲酯、异丁香酚、(E)-2-壬烯醛、2-乙酰基吡嗪、2-羟基-3-甲基-2-环戊烯-1-酮、顺-3-己烯醇、2-戊酮、己酸D、2-甲酰基-5-甲基噻吩、3-甲基丁醛、3-辛酮、甲硫醇以及未知化合物39、25、24、41、36、40、42、17、8、27、15、29、31、43、4、19的浓度远低于其余5种韭菜种子炮制样品,几乎与生品韭菜子相似;D框所示物质辛醇远高于其余所有炮制品,可作为韭菜子清炒品特征性挥发物质。(3)韭菜子酒炙样品(P2)与盐酒共炙样品(P6)具有共同的显著高于其他炮制品和生品的特征峰区域,主要体现在E框所示物质2-羟基丙酸乙酯和β-罗勒烯以及未知化合物12、14,其中β-罗勒烯又以酒炙品浓度最高,可分别作为韭菜子酒炙品和盐酒共炙品特征性挥发物质。(4)韭菜子蒸熟样品(P7)与其他炮制品的区别特征峰区域主要体现在F框所示物质糠醇、3-羟基-2-丁酮、丁内酯和芳樟醇,可作为韭菜子蒸熟品特征性挥发物质。(5)韭菜子醋炙样品与其他炮制品的区别特征峰区域主要体现在G框所示物质戊醛以及未知化合物11、44、45、46,可作为韭菜子醋炙品特征性挥发物质。(6)韭菜子盐炙样品(P3)与清炒样品(P5)在2-丙醇、乙酸、乙酸丙酯以及未知化合物13上表现出与清炒相似的浓度增加,且远高于其他炮制品,但在C框所示物质上又表现出与除清炒样品(P5)和生品(P1)外其他炮制品相似的转化作用,具体变化规律尚待进一步深入研究。
为直观且定量地比较不同样品之间的挥发性有机物差异,继续采用Galleryplot插件对指纹图谱中各物质进行定量分析,通过数据库比对,共识别差异化合物54种。结果见表2、插页ⅩⅪ图6。
由表2、插页ⅩⅪ图6可知,韭菜子从生品到炮制品,各化合物峰强度(面积)均有不同程度的增加或减少,说明其相应的物质含量亦在不同程度地增加或减少,增加或减少的量与峰强度(面积)成正比。其中,香叶醇、乙酰甲醇、正戊醇l、2-甲基丙醇、烯丙基硫醚、3-甲基-3-丁烯-1-醇、乙醇、丙酸、2-乙酰呋喃、2,5-二甲基呋喃、乙酸乙酯、二烯丙基二硫M、正戊基呋喃、己酸M和己酸乙酯等物质峰强度经炮制后集体减少,减少百分比在范围2.34% ~87.67%不等。其余化合物,除二烯丙基二硫醚D、丁酸戊酯、苯甲酸甲酯、己酸D、3-辛酮、苯甲醛、己醛、2-羟基丙酸乙酯、2,3-丁二醇l和糠醇等10种化合物在各炮制品中增减不同外,均呈增加趋势,增加范围在3.46%~1 699.89%不等。化合物二烯丙基二硫醚D、丁酸戊酯、苯甲酸甲酯、己酸D和3-辛酮仅在清炒品中呈略微减少趋势(6.41% ~26.68%),其余炮制品均是增加,可考虑作为GC-IMS鉴别分析的韭菜子清炒特征性挥发物质;苯甲醛仅在盐酒共炙中呈减少趋势,其余炮制品均是增加,可考虑作为GC-IMS鉴别分析的韭菜子盐酒共炙特征性挥发物质;2-羟基丙酸乙酯和糠醇则表现出相反的增减趋势,前者仅在酒炙和盐酒共炙品中表现出增加趋势,其余炮制品均是减少,后者在二者中则表现出减少,其余炮制品均是增加,可考虑作为GCIMS鉴别分析的韭菜子酒炙或盐酒共炙特征性挥发物质。
韭菜籽的外壳是非常坚硬的硬质纤维,加热炒制可使其种壳破裂,一方面可增加有效物质的溶出度,另一方面也可使质地酥脆而便于粉碎[14]。本实验中韭菜子生品经过炒制或蒸熟以后,有多达60%以上的有机挥发物种类峰强度(面积)和总峰强度(面积)均大幅度增加,故韭菜子古法炒用是具有一定科学道理的,也符合“逢子必炒”的中药炮制理论。其次传统中药炮制理论认为“盐味咸,咸入肾,盐炙引药入肾经,增强补肾助阳作用”“酒味辛、甘,性大热,热者益热,增强温阳祛寒作用”“醋味酸,酸入肝,引药入肝经,增强理气止痛作用”。韭菜子加入辅料盐、酒、醋炮制以后,均能在清炒的基础上进一步增加挥发性有机物的检出,此可能与盐、酒、醋的化学性质有关:一是可能使韭菜子所含挥发性有机物从与钾、钙等金属离子结合成的盐里游离出来,从而增加峰强度(面积)[15];二是可能酒[16]和醋[17]中本身含有一定量的挥发性有机物的混入,此二者均尚需进一步研究探索。
主要差异物质Diallyl disulfide,中文名为二烯丙基二硫(大蒜素),是一种淡黄色液体,有强烈的大蒜气味,具有抗癌[18]、护肝[19-20]、抗肺纤维化[21]、降血脂[22]、抗氧化[23-24]和抗炎[25-26]等多种作用,对许多类型的肿瘤细胞表现出抗肿瘤活性,包括肺癌、胃肠道及相关癌症(食道癌、胃癌、结直肠癌)、肝细胞癌细胞系等,具体表现为可显著降低四氯化碳肝损伤小鼠肝脏指数,降低天门冬氨酸氨基转移酶(Aspartate aminotransferase,AST)、碱性磷酸酶(Alkaline phosphatase,ALP)活力,提高超氧化物歧化酶(Superoxide dismutase,SOD)活力,减少肝脏组织损伤面积、细胞坏死、炎细胞浸润等;激活乙醇/乙醛脱氢酶的活性、抑制肝脏氧化应激、调控肠-肝轴和抑制肝脏NOD样受体热蛋白结构域相关蛋白3(Nod-like receptor heat Protein Domain Associated Protein 3,NLRP3)炎性小体激活,拮抗酒精诱导的小鼠肝脏炎症,并通过核因子E2相关因子2(Nuclear factor E2 related factor 2,Nrf2)依赖的方式减轻酒精诱导的肝脏脂肪蓄积;介导法尼醇X受体(Farnesoidx receptor,FXR)-Yes相关蛋白1(Yes-associated protein 1,YAP1)信号交互改善肺纤维化;降低血清中总胆固醇(Total cholesterol,TC)、甘油三酯(Triglyceride,TG)和低密度脂蛋白胆固醇(Low density lipoprotein cholesterol,LDL-C)水平,激活Kelch样环氧氯丙烷相关蛋白1(Kelch-like epichlorohydrin associated protein 1,Keap1)/Nrf2通路,并上调下游蛋白相关蛋白NAD(P)H脱氢酶醌1[NAD(P)H dehydrogenase quinone1,NQO1]、谷氨酸半胱氨酸合成酶(Glutamate-cysteine synthetase,γ-GCSc)、超氧化物歧化酶1(Superoxide dismutase 1,SOD-1)表达水平以改善肝脏氧化应激水平,减轻脂质过氧化,下调类固醇调节元件结合蛋白1c(Steroid regulatory element-binding protein 1c,SREBP1c)的表达,抑制肝脏TG及相关脂质的合成,上调肝脏细胞过氧化物酶体增殖物激活受体α(peroxisome proliferator-activated receptorα,PPARα)蛋白表达,加快TG分解及脂肪酸的氧化代谢等。此外,Pentyl butanoate、3-Octanone、Benzaldehyde和Hexanal亦均是具有气味的活性有机化合物。其中,Pentyl butanoate中文名为丁酸戊酯,是一种具有气味活性的有机化合物,已被确定为香蕉、杏和苹果中的主要风味成分之一[27];3-Octanone,中文名3-辛酮,是薰衣草型香精的调和香料,具有改善糖尿病患者冠心病风险等作用[28];Benzaldehyde,中文名苯甲醛,天然来源是苦杏仁苷,一种常见的芳香族化合物,GB2076-2011规定的允许使用的食品用合成香料,具有保护广州管圆线虫感染致小鼠脑损伤等作用[29];Hexanal,中文名正己醛,是一种主要的挥发性醛,可作为肺癌诊断的潜在生物标志物等[30]。上述物质均与韭菜子炮制后气味改变有关,亦需系统深入研究。
  • 国家中医药管理局中药炮制技术传承基地建设项目(国中医药科技中药便函〔2022〕59号)
  • 重庆市自然科学基金项目(CSTC2018JCYJAX0017)
  • 重庆市卫健委“十三五”市级中医药重点学科项目(渝中医〔2018〕43号)
参考文献 引证文献
排序方式:
[1]
高学敏. 中药学[M]. 北京:中国中医药出版社,2002:532-533
[2]
钟凌云. 中药炮制学[M]. 5版. 北京:中国中医药出版社,2021:238-239.
[3]
王雯萱,葛发欢,张湘东. 韭菜子挥发油的GC-MS分析[J]. 中药材,2015,38(6):1223-1224.
[4]
赵日虹,刘习平,周昭丽,等. 韭菜子化学成分、药理作用及质量标志物(Q-Marker)的预测分析[J]. 中药药理与临床,2023,39(11):121-128.
[5]
ZHU H,ZHU D Z,SUN JM. Application of GC-IMScoupled with chemometric analysis for the classification and authentication of geographical indication agricultural products and food[J]. Front Nutr,2023,10:1247695.
[6]
QIAO Y N,CHEN Q Q,BI J F,et al. Investigation of the volatile profile of red jujube by using GC-IMS,multivariate data analysis,and descriptive sensory analysis[J]. Foods,2022,11(3):421.
[7]
DUAN H,ZHOU Y X,WANGD D,et al. Differences in volatile organic compounds in Rhizoma gastrodiae(Tian Ma)of different origins determined by HS-GC-IMS[J]. Molecules,2023,28(13):4883.
[8]
DUAN H,ZHOU SQ,GUO J H,et al. HS-GC-IMSanalysis of volatile organic compounds in different varieties and harvesting times of Rhizoma gastrodiae(Tian Ma)in Yunnan Province[J]. Molecules,2023,28(18):6705.
[9]
YU X Y,CHEN X C,LI Y T,et al. Effect of drying methods on volatile compounds of Citrus reticulata ponkan and Chachi peels as characterized by GC-MS and GC-IMS[J]. Foods,2022,11(17):2662.
[10]
冯靖雯,郭小红,张砚,等. 不同花期闹羊花中挥发性成分的GC-IMS分析[J]. 中国实验方剂学杂志,2021,27(10):85-92.
[11]
WANG M,LI X,DING H Y,et al. Comparison of the volatile organic compounds in Citrus reticulata‘Chachi’peel with different drying methods using E-nose,GC-IMSand HS-SPME-GCMS[J]. Front Plant Sci,2023,14:1169321.
[12]
宋艺君,郭涛,高阳丽,等. GC-IMS法比较黄精不同炮制品特征气味物质差异[J]. 中国药学杂志,2022,57(16):1329-1336.
[13]
MA L K,LUO Y Y,CHEN B L,et al. Determination of characteristic volatile component fingerprint of Peucedanum praeruptorum dunn at different harvest periods based on HS-GC-IMS[J]. J AOACInt,2023,106(2):445-456.
[14]
吴文辉,刘霞,郭小红,等. 加热炒制对韭菜子出膏率、粉碎率及6种核苷类物质含量动态影响的研究[J]. 现代中药研究与实践,2021,35(3):47-50.
[15]
WANG P P,KAN Q X,YANG L X,et al. Characterization of the key aroma compounds in soy sauce by gas chromatography-mass spectrometry-olfactometry,headspace-gas chromatography-ion mobility spectrometry,odor activity value,and aroma recombination and omission analysis[J]. Food Chem,2023,419:135995.
[16]
YU H Y,LIQW,GUOW,et al. Dynamic analysis of volatile metabolites and microbial community and their correlations during the fermentation process of traditional Huangjiu(Chinese rice wine)produced around Winter Solstice[J]. Food Chem X,2023,18:100620.
[17]
SUN D D,LI W X,LUO L X. Deciphering the brewing process of Cantonese-style rice vinegar:main flavors,key physicochemical factors,and important microorganisms[J]. Food Res Int,2023,171:113068.
[18]
MITRA S,DASR,EMRAN T B,et al. Diallyl disulfide:a bioactive garlic compound with anticancer potential[J]. Front Pharmacol,2022,13:943967.
[19]
黎晶晶,余天,袁娟丽,等. 大蒜素分解产物二烯丙基二硫对小鼠急性肝损伤的保护作用[J]. 食品安全质量检测学报,2023,14(5):308-316.
[20]
刘诗旋. 二烯丙基二硫通过调控“肠-肝轴”和维持肝细胞脂肪代谢稳态减轻酒精性肝病[D]. 济南:山东大学,2023.
[21]
窦佳艺. 二烯丙基二硫介导FXR——YAP1信号交互改善肺纤维化的研究[D]. 延吉:延边大学,2022.
[22]
王琼. 二烯丙基二硫对高脂血症大鼠的降血脂效果和机制研究[D]. 济南:山东大学,2019.
[23]
HERRERA-CALDERON O,CHACALTANA-RAMOS L J,HUAYANCA-GUTIÉRREZ I C,et al. Chemical constituents,in vitro antioxidant activity and in silico study on NADPH oxidase of Allium sativum L. (garlic)essential oil[J]. Antioxidants,2021,10(11):1844.
[24]
WONGMANEEPRATIP W,JOM K N,VANGNAI K. Inhibitory effects of dietary antioxidants on the formation of carcinogenic polycyclic aromatic hydrocarbons in grilled pork[J]. Asian-Australas J Anim Sci,2019,32(8):1205-1210.
[25]
ZHANG H X,SHANG C,TIAN Z,et al. Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice[J]. Mediators Inflamm,2020,2020:8508906.
[26]
GAO W Q,WANGW,LIUG,et al. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome[J]. Metab Brain Dis,2019,34(1):319-329.
[27]
WU X Y,FAUCONNIER M L,BI J F. Characterization and discrimination of apples by flash GCE-nose:geographical regionsand botanical origins studies in China[J]. Foods,2022,11(11):1631.
[28]
SHEN M,XIE Q Y,ZHANG R Z,et al. Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes[J]. Front Pharmacol,2023,14:1175021.
[29]
CHEN K Y,CHENG C J,CHEN Y J,et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. Int J Antimicrob Agents,2023,62(5):106963.
[30]
AZORÍN C,LÓPEZ-JUAN A L,APARISI F,et al. Determination of hexanal and heptanal in saliva samples by an adapted magnetic headspace adsorptive microextraction for diagnosis of lung cancer[J]. Anal Chim Acta,2023,1271:341435.
2025年第43卷第5期
PDF下载
13
4
引用本文
BibTeX
文章信息
doi: 10.13193/j.issn.1673-7717.2025.05.014
  • 首发时间:2026-10-30
  • 出版时间:2025-05-10
补充材料
相关文章
文章信息
作者
出版历史
基金
国家中医药管理局中药炮制技术传承基地建设项目(国中医药科技中药便函〔2022〕59号)
重庆市自然科学基金项目(CSTC2018JCYJAX0017)
重庆市卫健委“十三五”市级中医药重点学科项目(渝中医〔2018〕43号)
作者信息
    重庆市中医院,重庆 400021

通讯作者:

吴文辉(1986-),男,四川绵阳人,副主任中药师,博士,研究方向:中药炮制原理。E-mail:。
参考文献
分享链接
https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2025.05.014
分享至
全文二维码

扫描看全文

引用本文
BibTeX
本文的引用情况
2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏