Article(id=1319291680239498006, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.040, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473247822, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473247822, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473247822, creator=13701087609, updateTime=1792473247822, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=226, endPage=229, ext={EN=ArticleExt(id=1319291680461796119, articleId=1319291680239498006, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Clinical Observation of Changge Buyang Huanwu Decoction (菖葛补阳还五汤) Combined with Edaravone Dextrocamphorol in Treatment of Acute Cerebral Infarction, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To observe the clinical effect of Changge Buyang Huanwu Decoction (菖葛补阳还五汤) combined with edaravone dexcamphorol in the treatment of acute cerebral infarction.
Methods A total of 102 cases of acute cerebral infarction admitted from February 2022 to June 2024 were divided into western medicine group and combined decoction group by random number table method, with 51 cases in each group. The patients in the western medicine group were treated with edaravone dexcamphorol, while those in the combined decoction group were treated with Changge Buyang Huanwu Decoction combined with edaravone dexcamphorol, and the therapeutic effect of the two groups was evaluated. The self-care function of the patients was evaluated by Barthel index and the total score of TCM symptoms, the levels of interleukin-8 (IL-8), interleukin-10 (interleukin-10), hypersensitive C-reactive protein (hs-CRP) and other serum inflammatory factors, the changes of oxidative stress indexes such as superoxide dismutase (SOD) and malondialdehyde (MDA), the resistance index (RI), the changes in cerebral blood flow indexes such as cerebral blood volume (CBV), time to peak blood flow (TTP), homocystine (Hcy) and neuron-specific enolase (NSE) of the patients in both groups before and after treatment and the adverse reactions were compared.
Results Compared with that of the western medicine group (80.39%, 41/51), the index of the combined decoction group (96.08%, 49/51) was higher (P<0.05). Barthel index, total TCM symptom scores, the levels of IL-8, IL-10, hs-CRP, SOD and MDA, the values of RI, CBV, TTP, Hcy, NSE and other indexes were not significant between the two groups before treatment (P>0.05). After treatment, the levels of these indexes were improved in both groups and the results in the combined decoction group were all better than those in the western medicine group (P<0.05). There were fewer adverse reactions in the western medicine group and combined decoction group (P>0.05).
Conclusion The combination of Changge Buyang Huanwu Decoction and edaravone dextrocamphorol exhibits the favorable clinical outcomes in the management of acute cerebral infarction. It effectively facilitates the rehabilitation, demonstrating safety and reliability, and thus merits the consideration for application.
, authors=Caina XU, Shanshan JU, Modan XIN, Lizhen CHI, Qi YU, Moju XU, Shasha LU, Yinling GUO, authorsList=Caina XU, Shanshan JU, Modan XIN, Lizhen CHI, Qi YU, Moju XU, Shasha LU, Yinling GUO, authorCompany=null, correspAuthors=Yinling GUO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291680801534744, articleId=1319291680239498006, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=菖葛补阳还五汤联合依达拉奉右莰醇治疗急性脑梗死临床效果观察, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 观察菖葛补阳还五汤联合依达拉奉右莰醇治疗急性脑梗死临床效果。
方法 研究纳入102例急性脑梗死患者（2022年2月—2024年6月收治），采取随机数字表法分为联合汤剂组及西药组，每组51例。西药组患者采取依达拉奉右莰醇治疗，联合汤剂组患者采取菖葛补阳还五汤联合依达拉奉右莰醇治疗，评估两组治疗效果，采取巴塞尔指数（Barthel index，Barthel）评估患者自理功能，并比较治疗前后两组患者中医证候总积分变化、白细胞介素-10（Interleukin-10，IL-10）、白细胞介素-8（Interleukin-8，IL-8）、超敏C反应蛋白（hs-CRP）等血清炎症因子指标变化、超氧化物歧化酶（Superoxide dismutase，SOD）及丙二醛（Malondialdehyde，MDA）等氧化应激指标变化、颅脑血流阻力指数（resistance index，RI）、脑血容量（cerebral blood volume，CBV）、血流峰值时间（time to peak，TTP）等脑血流量指标变化、同型半胱氨酸（Homocystine，Hcy）及神经元特异性烯醇化酶（neuron-specific enolase，NSE）指标变化、不良反应。
结果 较西药组治疗总有效率（80.39%，41/51），联合汤剂组患者指标（96.08%，49/51）更高（P<0.05）；治疗前两组患者Barthel指数、中医证候总积分、IL-8、IL-10、hs-CRP、SOD及MDA、RI、CBV、TTP、Hcy、NSE等指标比较，差异无统计学意义（P>0.05）；治疗后两组患者Barthel指数、中医证候总积分、IL-8、IL-10、hs-CRP、SOD及MDA、RI、CBV、TTP、Hcy、NSE等指标均改善，联合汤剂组治疗后Barthel指数、中医证候总积分、IL-8、IL-10、hs-CRP、SOD及MDA、RI、CBV、TTP、Hcy、NSE等指标均优于西药组（P<0.05）；西药组及联合汤剂组患者不良反应均较少（P>0.05）。
结论 菖葛补阳还五汤联合依达拉奉右莰醇治疗急性脑梗死临床效果良好，可较好促进患者康复，治疗安全可靠，值得应用。
, authors=徐彩娜, 俱闪闪, 辛末丹, 池立珍, 于奇, 许墨菊, 卢莎莎, 郭银玲, authorsList=徐彩娜, 俱闪闪, 辛末丹, 池立珍, 于奇, 许墨菊, 卢莎莎, 郭银玲, authorCompany=null, correspAuthors=郭银玲, authorNote=
徐彩娜（1984-），女，河北文安人，副主任医师，硕士，研究方向：脑血管病。
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徐彩娜（1984-），女，河北文安人，副主任医师，硕士，研究方向：脑血管病。
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