Article(id=1319291593895555123, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.020, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473227237, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473227237, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473227237, creator=13701087609, updateTime=1792473227237, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=105, endPage=112, ext={EN=ArticleExt(id=1319291594130436148, articleId=1319291593895555123, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Dahuang (Rhei Radix et Rhizoma) and Its Active Ingredients in Treatment of Mental Diseases, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Mental illnesses are diseases that seriously affect the physical and mental health of human beings and their social functions. Traditional Chinese medicine has important advantages in preventing and treating mental illness. It can “prevent illness before it occurs”, effectively relieve many “indescribable” symptoms, and alleviate various side effects caused by Western medicine. Dahuang (Rhei Radix et Rhizoma) is a common traditional Chinese medicine, which is widely used in the treatment of mental diseases, such as schizophrenia, depression, insomnia, etc. Dahuang (Rhei Radix et Rhizoma)-related formulas, such as Chengqi Tang (承气汤), Dachaihu Tang (大柴胡汤) and Chaihu Jia Longgumuli Tang (柴胡加龙骨牡蛎汤), are commonly used by ancient physicians in the treatment of mental diseases. Modern pharmacological mechanisms show that the anthraquinone components in Dahuang (Rhei Radix et Rhizoma) are the core components of its function. It has been shown that Dahuang (Rhei Radix et Rhizoma) components help to improve inflammatory damage, neurodevelopmental damage, neurotransmitter disorders, intestinal flora disorders and sexual hormone disturbance in psychiatric disorders, and that Dahuang (Rhei Radix et Rhizoma) monomers such as rheum emodin have exerted a stable effect on improving the pathological damage of psychiatric disorders, and that research on Dahuang (Rhei Radix et Rhizoma) components and dosage forms is becoming more and more in-depth, which is expected to be more widely used in the treatment of mental illness in the future. The active ingredients, clinical studies and pharmacological mechanisms of Dahuang (Rhei Radix et Rhizoma) in the treatment of psychiatric disorders were systematically discussed with a view to providing references for the treatment and research of psychiatric disorders.

, authors=Sihan ZHAO¹, Aineng PENG², Yonghou ZHAO¹, Hao ZHANG², Jianbo CHAI¹, authorsList=Sihan ZHAO, Aineng PENG, Yonghou ZHAO, Hao ZHANG, Jianbo CHAI, authorCompany=null, correspAuthors=Hao ZHANG, Jianbo CHAI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291594700861493, articleId=1319291593895555123, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=大黄及其有效成分治疗精神疾病研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

精神疾病是严重影响人类身心健康和社会功能的一类疾病。中医药在防治精神疾病方面具有重要优势，可以“未病先防”，有效缓解许多“未可名状”的症状，缓解西药所致的各种不良反应。大黄是常见的传统中医药，在治疗精神疾病的治疗中应用颇广，在治疗精神分裂症、抑郁症、失眠症等病中均有应用。大黄相关的方剂如承气汤类方、柴胡加龙骨牡蛎汤、大柴胡汤是古代医家治疗精神疾病常用方。现代药理学机制表明，大黄中的蒽醌类成分是其发挥作用的核心成分，大黄成分有助于改善精神疾病的炎症损伤、神经发育损伤、神经递质紊乱、肠道菌群紊乱等情况，大黄单体如大黄素发挥出较为稳定的改善精神疾病病理损伤的作用。关于大黄成分及剂型的研究越来越深入，未来有望更广泛地应用于精神疾病的治疗。对大黄治疗精神疾病的有效成分、临床研究及药理机制进行系统论述，以期为精神疾病的治疗和研究提供参考。

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赵思涵（2000-），女，黑龙江哈尔滨人，医师，硕士，研究方向：神志病临床及基础。

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赵思涵（2000-），女，黑龙江哈尔滨人，医师，硕士，研究方向：神志病临床及基础。

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Incidence, prevalence, and global burden of schizophrenia-data, with critical appraisal, from the Global Burden of Disease (GBD)2019[J]. Mol Psychiatry, 2023, 28(12): 5319-5327., articleTitle=null, refAbstract=null), Reference(id=1319291599234904167, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=WORLD HEALTH ORGANIZATION. Constitution of the World Health Organization[EB/OL]. [2016-06-22]. http://apps.who.int/gb/bd/PDF/bd47/EN/constitution-en.pdf1., articleTitle=null, refAbstract=null), Reference(id=1319291599314595944, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=KENDLER K S, EAVES L J. Psychiatric Genetics, Review of Psychiatry[M]. Arlington, VA: American Psychiatric Publishing, Inc, 2005., articleTitle=null, refAbstract=null), Reference(id=1319291599381704809, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=KENDLER K S. Twin studies of psychiatric illness: an update[J]. Arch Gen Psychiatry, 2001, 58(11): 1005-1014., articleTitle=null, refAbstract=null), Reference(id=1319291599461396586, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=KENDLER K S, PRESCOTT C A, MYERS J, et al. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women[J]. Arch Gen Psychiatry, 2003, 60(9): 929-937., articleTitle=null, refAbstract=null), Reference(id=1319291599532699755, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=SMOLLER J W, ANDREASSEN O A, EDENBERG H J, et al. Psychiatric genetics and the structure of psychopathology[J]. Mol Psychiatry, 2019, 24(3): 409-420., articleTitle=null, refAbstract=null), Reference(id=1319291599604002924, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=GOH C, AGIUS M. The stress-vulnerability model how does stress impact on mental illness at the level of the brain and what are the consequences?[J]. Psychiatr Danub, 2010, 22(2): 198-202., articleTitle=null, refAbstract=null), Reference(id=1319291599671111789, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=SCHÄFER J Ö, NAUMANN E, HOLMES E A, et al. Emotion regulation strategies in depressive and anxiety symptoms in youth: a meta-analytic review[J]. J Youth Adolesc, 2017, 46(2): 261-276., articleTitle=null, refAbstract=null), Reference(id=1319291599738220654, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=SABELLA D. Antidepressant medications[J]. Am J Nurs, 2018, 118(9): 52-59., articleTitle=null, refAbstract=null), Reference(id=1319291599801135215, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=RYBAKOWSKI J K. Lithium-past, present, future[J]. Int J Psychiatry Clin Pract, 2020, 24(4): 330-340., articleTitle=null, refAbstract=null), Reference(id=1319291599868244080, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=BALON R, STARCEVIC V. Role of benzodiazepines in anxiety disorders[J]. Adv Exp Med Biol, 2020, 1191: 367-388., articleTitle=null, refAbstract=null), Reference(id=1319291599943741553, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=HUANG X F, YANG J, YANG S J, et al. Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms[J]. Oncotarget, 2017, 8(60): 102705-102720., articleTitle=null, refAbstract=null), Reference(id=1319291600006656114, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=YANG X R, DAI L X, YAN F Y, et al. The phytochemistry and pharmacology of three Rheum species: a comprehensive review with future perspectives[J]. Phytomedicine, 2024, 131: 155772., articleTitle=null, refAbstract=null), Reference(id=1319291600090542195, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=MITRA S, ANJUM J, MUNI M, et al. Exploring the journey of emodin as a potential neuroprotective agent: Novel therapeutic insights with molecular mechanism of action[J]. Biomedecine Pharmacother, 2022, 149: 112877., articleTitle=null, refAbstract=null), Reference(id=1319291600178622580, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=沈娜. 干燥对掌叶大黄活性物质组分变化及其保肝活性的影响[D]. 兰州: 甘肃农业大学, 2023., articleTitle=null, refAbstract=null), Reference(id=1319291600245731445, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=张桥, 陈艳琰, 乐世俊, 等. 大黄及其不同炮制品中16种化学成分的含量变化研究[J]. 中华中医药杂志, 2022, 37(2): 1036-1040., articleTitle=null, refAbstract=null), Reference(id=1319291600312840310, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHAO D, FENG S X, ZHANG H J, et al. Pharmacokinetics, tissue distribution and excretion of five rhubarb anthraquinones in rats after oral administration of effective fraction of anthraquinones from Rheum officinale[J]. Xenobiotica, 2021, 51(8): 916-925., articleTitle=null, refAbstract=null), Reference(id=1319291600375754871, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=王玉, 杨雪, 夏鹏飞, 等. 大黄化学成分、药理作用研究进展及质量标志物的预测分析[J]. 中草药, 2019, 50(19): 4821-4837., articleTitle=null, refAbstract=null), Reference(id=1319291600451252344, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=张开弦, 姚秋阳, 吴发明, 等. 大黄属药用植物化学成分及药理作用研究进展[J]. 中国新药杂志, 2022, 31(6): 555-566., articleTitle=null, refAbstract=null), Reference(id=1319291600539332729, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=赵凤仙, 麦蓝尹, 谢臻, 等. 中药蒽醌类成分的药理作用及其机制研究进展[J]. 壮瑶药研究, 2023(1): 152-154, 313., articleTitle=null, refAbstract=null), Reference(id=1319291600606441594, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=谢蓉, 张民权, 李莹, 等. 大黄素药理作用及新剂型研究进展[J]. 中华中医药学刊, 2023, 41(12): 120-125., articleTitle=null, refAbstract=null), Reference(id=1319291600690327675, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=原凤蕉. 芦荟大黄素衍生物的合成及其抗肿瘤活性的研究[D]. 沈阳: 沈阳化工大学, 2021., articleTitle=null, refAbstract=null), Reference(id=1319291600770019452, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=刘昱航. 双醋瑞因治疗骨关节炎疗效和安全性的Meta分析[D]. 右江: 右江民族医学院, 2023., articleTitle=null, refAbstract=null), Reference(id=1319291602309329021, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=汪祺, 杨建波, 王莹, 等. 大黄素甲醚大鼠体内毒代动力学研究[J]. 中国药学杂志, 2022, 57(19): 1666-1672., articleTitle=null, refAbstract=null), Reference(id=1319291602384826494, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=王脉. Pluronic-大黄酚胶束制备工艺及药物代谢动力学研究[D]. 张家口: 河北北方学院, 2022., articleTitle=null, refAbstract=null), Reference(id=1319291602464518271, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=SU S Y, WU J S, GAO Y, et al. The pharmacological properties of chrysophanol, the recent advances[J]. Biomedecine Pharmacother, 2020, 125: 110002., articleTitle=null, refAbstract=null), Reference(id=1319291602527432832, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=李冀. 番泻苷A通腑泄下的作用及机制研究[D]. 西安: 中国人民解放军空军军医大学, 2019., articleTitle=null, refAbstract=null), Reference(id=1319291602598736001, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=null, journalName=null, refType=null, unstructuredReference=LE J M, JI H L, ZHOU X X, et al. Pharmacology, toxicology, and metabolism of sennoside A, A medicinal plant-derived natural compound[J]. Front Pharmacol, 2021, 12: 714586., articleTitle=null, refAbstract=null), Reference(id=1319291602678427778, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=null, journalName=null, refType=null, unstructuredReference=HWANG I Y, JEONG C S. Gastroprotective activities of sennoside A and sennoside B via the up-regulation of prostaglandin E2 and the inhibition of H(+)/K(+)-ATPase[J]. Biomol Ther (Seoul), 2015, 23(5): 458-464., articleTitle=null, refAbstract=null), Reference(id=1319291602758119555, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[31], rfOrder=30, authorNames=null, journalName=null, refType=null, unstructuredReference=WU H Y, FENG F, JIANG X N, et al. Pharmacokinetic and metabolic profiling studies of sennoside B by UPLC-MS/MS and UPLC-Q-TOF-MS[J]. J Pharm Biomed Anal, 2020, 179: 112938., articleTitle=null, refAbstract=null), Reference(id=1319291602829422724, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[32], rfOrder=31, authorNames=null, journalName=null, refType=null, unstructuredReference=SAHIN H, ERBA爦O. Beneficial effects of sennoside B on pentyle-netetrazole-induced seizures in rats[J]. Hum Exp Toxicol, 2023, 42: 9603271231168764., articleTitle=null, refAbstract=null), Reference(id=1319291602900725893, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[33], rfOrder=32, authorNames=null, journalName=null, refType=null, unstructuredReference=QIN Y, WANG J B, KONG W J, et al. The diarrhoeogenic and antidiarrhoeal bidirectional effects of rhubarb and its potential mechanism[J]. J Ethnopharmacol, 2011, 133(3): 1096-1102., articleTitle=null, refAbstract=null), Reference(id=1319291602963640454, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[34], rfOrder=33, authorNames=null, journalName=null, refType=null, unstructuredReference=LIU C F, ZHENG Y F, XU W, et al. Rhubarb tannins extract inhibits the expression of aquaporins 2 and 3 in magnesium sulphate-induced diarrhoea model[J]. Biomed Res Int, 2014, 2014: 619465., articleTitle=null, refAbstract=null), Reference(id=1319291603026555015, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[35], rfOrder=34, authorNames=null, journalName=null, refType=null, unstructuredReference=DAI C M, WANG J B, KONG W J, et al. Investigation of anti-microbial activity of catechin on Escherichia coli growth by microcalorimetry[J]. Environ Toxicol Pharmacol, 2010, 30(3): 284-288., articleTitle=null, refAbstract=null), Reference(id=1319291603085275272, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[36], rfOrder=35, authorNames=null, journalName=null, refType=null, unstructuredReference=BERNATONIENE J, KOPUSTINSKIENE D M. The role of catechins in cellular responses to oxidative stress[J]. Molecules, 2018, 23(4): 965., articleTitle=null, refAbstract=null), Reference(id=1319291603156578441, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[37], rfOrder=36, authorNames=null, journalName=null, refType=null, unstructuredReference=WIANOWSKA D, OLSZOWY-TOMCZYK M. A concise profile of Gallic acid-from its natural sources through biological properties and chemical methods of determination[J]. Molecules, 2023, 28(3): 1186., articleTitle=null, refAbstract=null), Reference(id=1319291603219493002, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[38], rfOrder=37, authorNames=null, journalName=null, refType=null, unstructuredReference=段展辉, 刘桂荣. 从量效关系探讨张志远运用大黄经验[J]. 中医杂志, 2022, 63(13): 1219-1222., articleTitle=null, refAbstract=null), Reference(id=1319291603286601867, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[39], rfOrder=38, authorNames=null, journalName=null, refType=null, unstructuredReference=王美珍, 孙玲, 郭文, 等. 大黄治疗狂症58例[C]//中国中西医结合学会第七届精神疾病学术讨论会论文汇编. 南昌: 2002., articleTitle=null, refAbstract=null), Reference(id=1319291603345322124, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[40], rfOrder=39, authorNames=null, journalName=null, refType=null, unstructuredReference=杨永和, 刘冬梅, 徐进. 大黄合并无抽搐电休克治疗精神分裂症的疗效与安全性分析[J]. 中国实验方剂学杂志, 2013, 19(24): 335-337., articleTitle=null, refAbstract=null), Reference(id=1319291603399848077, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[41], rfOrder=40, authorNames=null, journalName=null, refType=null, unstructuredReference=张海滨, 田金洲. 复方大黄胶囊对老年人多发梗塞性痴呆认知障碍的影响[J]. 中国医药学报, 2002(6): 353-356., articleTitle=null, refAbstract=null), Reference(id=1319291603462762638, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[42], rfOrder=41, authorNames=null, journalName=null, refType=null, unstructuredReference=TIAN J, DU H, YANG H, et al. A clinical study on compound da huang (radix et Rhizoma rhei) preparations for improvement of senile persons' memory ability[J]. J Tradit Chin Med. 1997, 17(3): 168-173., articleTitle=null, refAbstract=null), Reference(id=1319291603525677199, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[43], rfOrder=42, authorNames=null, journalName=null, refType=null, unstructuredReference=董自安. “大黄饮”的临床运用[J]. 江西中医药, 1995(3): 34., articleTitle=null, refAbstract=null), Reference(id=1319291603596980368, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[44], rfOrder=43, authorNames=null, journalName=null, refType=null, unstructuredReference=CHIAO Y W, LIVNEH H, GUO H R, et al. Use of Chinese herbal medicines is related to a reduction in depression risk among patients with insomnia: a matched cohort study[J]. Front Neurol, 2020, 11: 583485., articleTitle=null, refAbstract=null), Reference(id=1319291603659894929, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[45], rfOrder=44, authorNames=null, journalName=null, refType=null, unstructuredReference=刘朴霖, 阎兆君, 刘建民, 等. 张志远运用大黄治疗神志病经验[J]. 中医杂志, 2022, 63(8): 710-713., articleTitle=null, refAbstract=null), Reference(id=1319291603731198098, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[46], rfOrder=45, authorNames=null, journalName=null, refType=null, unstructuredReference=丁德正. 三承气汤在精神疾病临床的运用[J]. 中华中医药杂志, 2008(2): 134-137., articleTitle=null, refAbstract=null), Reference(id=1319291603819278483, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[47], rfOrder=46, authorNames=null, journalName=null, refType=null, unstructuredReference=丁德正. 桃核承气汤在精神疾病中的应用[J]. 河南中医, 2008(3): 21-22., articleTitle=null, refAbstract=null), Reference(id=1319291603898970260, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[48], rfOrder=47, authorNames=null, journalName=null, refType=null, unstructuredReference=赵霞, 闫少校. 柴胡加龙骨牡蛎汤在精神疾病中的应用[J]. 北京中医药, 2019, 38(12): 1183-1185., articleTitle=null, refAbstract=null), Reference(id=1319291603974467733, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[49], rfOrder=48, authorNames=null, journalName=null, refType=null, unstructuredReference=丁德正. 大柴胡汤治疗精神疾病验案举隅[J]. 河南中医, 2017, 37(9): 1518-1519., articleTitle=null, refAbstract=null), Reference(id=1319291604033187990, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[50], rfOrder=49, authorNames=null, journalName=null, refType=null, unstructuredReference=沈禹泽, 严辞, 郜彬, 等. 氧化应激因子水平与精神分裂症患者认知功能的相关性[J]. 中国医药导报, 2021, 18(20): 100-103., articleTitle=null, refAbstract=null), Reference(id=1319291604100296855, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[51], rfOrder=50, authorNames=null, journalName=null, refType=null, unstructuredReference=李蕾, 郑海霞, 戴欧阳, 等. 阿尔茨海默症发生机制及脂质代谢在其中的作用[J]. 湖南师范大学学报(医学版), 2023, 20(3): 1-9., articleTitle=null, refAbstract=null), Reference(id=1319291604175794328, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[52], rfOrder=51, authorNames=null, journalName=null, refType=null, unstructuredReference=赵文艳, 胡营营, 周玉亮, 等. 慢性低度炎症与焦虑、抑郁状态的相关性分析[J]. 联勤军事医学, 2023, 37(10): 866-870., articleTitle=null, refAbstract=null), Reference(id=1319291604238708889, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[53], rfOrder=52, authorNames=null, journalName=null, refType=null, unstructuredReference=牛静. 难治性抑郁症患者血浆非酶类抗氧化物和甲状腺激素及认知水平分析[D]. 青岛: 青岛大学, 2021., articleTitle=null, refAbstract=null), Reference(id=1319291604301623450, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[54], rfOrder=53, authorNames=null, journalName=null, refType=null, unstructuredReference=马成芳. 大黄水提物小鼠体内毒性及抗氧化功效研究[D]. 兰州: 兰州大学, 2023., articleTitle=null, refAbstract=null), Reference(id=1319291604372926619, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[55], rfOrder=54, authorNames=null, journalName=null, refType=null, unstructuredReference=张广发, 蔡颖莹, 林龙, 等. 基于PI3K/AKT/mTOR信号通路探讨大黄煎剂对轻微型肝性脑病大鼠脑组织炎症损伤的保护机制[J]. 临床肝胆病杂志, 2024, 40(2): 312-318., articleTitle=null, refAbstract=null), Reference(id=1319291604440035484, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[56], rfOrder=55, authorNames=null, journalName=null, refType=null, unstructuredReference=YANG W T, KE C Y, WU W T, et al. Antimicrobial and anti-inflammatory potential of Angelica dahurica and Rheum officinale extract accelerates wound healing in Staphylococcus aureus-infected wounds[J]. Sci Rep, 2020, 10(1): 5596., articleTitle=null, refAbstract=null), Reference(id=1319291604502950045, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[57], rfOrder=56, authorNames=null, journalName=null, refType=null, unstructuredReference=LIUDVYTSKA O, BANDYSZEWSKA M, SKIRECKI T, et al. Anti-inflammatory and antioxidant actions of extracts from Rheum rhaponticum and Rheum rhabarbarum in human blood plasma and cells in vitro[J]. Biomed Pharmacother, 2023, 165: 115111., articleTitle=null, refAbstract=null), Reference(id=1319291604565864606, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[58], rfOrder=57, authorNames=null, journalName=null, refType=null, unstructuredReference=黄丽英, 林新华, 陈伟, 等. 芦荟大黄素、芦荟素清除氧自由基作用的研究[J]. 中国医院药学杂志, 2006(1): 12-14., articleTitle=null, refAbstract=null), Reference(id=1319291604641362079, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[59], rfOrder=58, authorNames=null, journalName=null, refType=null, unstructuredReference=WANG L C, LIU S T, XU J Q, et al. Emodin inhibits aggregation of amyloid-β peptide 1-42 and improves cognitive deficits in Alzheimer's disease transgenic mice[J]. J Neurochem, 2021, 157(6): 1992-2007., articleTitle=null, refAbstract=null), Reference(id=1319291604712665248, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[60], rfOrder=59, authorNames=null, journalName=null, refType=null, unstructuredReference=蔡友德, 何前松, 胡斐然, 等. 大黄酸对脑缺血大鼠脑组织中AQP4和小胶质细胞介导炎症反应的影响[J]. 中国实验方剂学杂志, 2021, 27(2): 60-65., articleTitle=null, refAbstract=null), Reference(id=1319291604792357025, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[61], rfOrder=60, authorNames=null, journalName=null, refType=null, unstructuredReference=蔡依琳, 朱乐玫, 陈彬, 等. CUMS抑郁小鼠模型海马氧化损伤的研究及大黄酚的保护作用[J]. 生物化工, 2023, 9(4): 31-34., articleTitle=null, refAbstract=null), Reference(id=1319291604872048802, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[62], rfOrder=61, authorNames=null, journalName=null, refType=null, unstructuredReference=吕昌迎, 边俊莉, 李伟. 基于NGF/TrkA通路探究大黄素对缺氧复氧诱导的PC12细胞凋亡及氧化损伤的影响[J]. 中国免疫学杂志, 2025, 41(3): 566-570., articleTitle=null, refAbstract=null), Reference(id=1319291604951740579, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[63], rfOrder=62, authorNames=null, journalName=null, refType=null, unstructuredReference=杨静涵, 景永帅, 张丹参. 大黄酚对脑缺血再灌注损伤的神经保护作用及机制[J]. 中国药理学与毒理学杂志, 2023, 37(7): 500-501., articleTitle=null, refAbstract=null), Reference(id=1319291605035626660, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[64], rfOrder=63, authorNames=null, journalName=null, refType=null, unstructuredReference=YAN N, WANG S, GAO H T, et al. Neuroprotective effect of Aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice[J]. Food Funct, 2023, 14(11): 5205-5216., articleTitle=null, refAbstract=null), Reference(id=1319291605111124133, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[65], rfOrder=64, authorNames=null, journalName=null, refType=null, unstructuredReference=雷鑫, 叶树, 王国权, 等. 芦荟大黄素对阿尔茨海默病大鼠PI3K/AKT/mTOR通路介导自噬的影响[J]. 安徽中医药大学学报, 2022, 41(3): 71-78., articleTitle=null, refAbstract=null), Reference(id=1319291605182427302, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[66], rfOrder=65, authorNames=null, journalName=null, refType=null, unstructuredReference=张笑颜, 王谢, 王杰, 等. 大黄酚调控AMPK/mTOR自噬信号通路改善Wilson病铜负荷大鼠认知功能[J]. 中国中西医结合杂志, 2023, 43(5): 578-584., articleTitle=null, refAbstract=null), Reference(id=1319291605249536167, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[67], rfOrder=66, authorNames=null, journalName=null, refType=null, unstructuredReference=马青艳, 董莹莹, 文炳龙, 等. 急性期精神分裂症患者血清神经递质与细胞因子水平的相关性[J]. 山西医科大学学报, 2023, 54(12): 1647-1652., articleTitle=null, refAbstract=null), Reference(id=1319291606914674856, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[68], rfOrder=67, authorNames=null, journalName=null, refType=null, unstructuredReference=颜瑞. 抑郁症患者血清谷氨酸、γ-氨基丁酸的水平及其临床意义[J]. 国际精神病学杂志, 2022, 49(4): 609-611., articleTitle=null, refAbstract=null), Reference(id=1319291607015338153, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[69], rfOrder=68, authorNames=null, journalName=null, refType=null, unstructuredReference=孙志国, 杨巍, 冯萍萍, 等. 广泛性焦虑症患者血清神经递质及凝血相关指标的变化分析[J]. 中国实用神经疾病杂志, 2016, 19(16): 36-37., articleTitle=null, refAbstract=null), Reference(id=1319291607090835627, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[70], rfOrder=69, authorNames=null, journalName=null, refType=null, unstructuredReference=刘振, 周宁, 刘通, 等. 大黄水提物对正常大鼠干预机制的代谢组学研究[J]. 中成药, 2023, 45(4): 1331-1338., articleTitle=null, refAbstract=null), Reference(id=1319291607342493868, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[71], rfOrder=70, authorNames=null, journalName=null, refType=null, unstructuredReference=GU J W, HASUO H, TAKEYA M, et al. Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro[J]. Neuropharmacology, 2005, 49(1): 103-111., articleTitle=null, refAbstract=null), Reference(id=1319291607405408429, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[72], rfOrder=71, authorNames=null, journalName=null, refType=null, unstructuredReference=XU N G, XIAO Z J, ZOU T, et al. Ameliorative effects of physcion 8-O-β-glucopyranoside isolated from Polygonum cuspidatum on learning and memory in dementia rats induced by Aβ1-40[J]. Pharm Biol, 2015, 53(11): 1632-1638., articleTitle=null, refAbstract=null), Reference(id=1319291607472517294, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[73], rfOrder=72, authorNames=null, journalName=null, refType=null, unstructuredReference=周红伟, 张惠实, 朱宏飞, 等. 大黄素对大鼠抑郁症行为学变化和脑内单胺类神经递质的影响[J]. 华中科技大学学报(医学版), 2017, 46(2): 150-154., articleTitle=null, refAbstract=null), Reference(id=1319291607766118575, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[74], rfOrder=73, authorNames=null, journalName=null, refType=null, unstructuredReference=童妍, 金钊, 赵焕瑛. 大黄素甲醚对慢性轻度不可预见应激大鼠海马单胺类神经递质的影响[J]. 中药药理与临床, 2015, 31(1): 54-57., articleTitle=null, refAbstract=null), Reference(id=1319291607829033136, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[75], rfOrder=74, authorNames=null, journalName=null, refType=null, unstructuredReference=聂银利, 段学清, 陈瑞, 等. 大黄对大鼠肠道菌群的影响[J]. 实用中医药杂志, 2021, 37(4): 529-535., articleTitle=null, refAbstract=null), Reference(id=1319291607887753393, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[76], rfOrder=75, authorNames=null, journalName=null, refType=null, unstructuredReference=高羽, 殷姗, 庞玥, 等. 大黄对大鼠体内肠道菌群-宿主共代谢作用的影响[J]. 上海交通大学学报(医学版), 2023, 43(8): 997-1007., articleTitle=null, refAbstract=null), Reference(id=1319291607959056562, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[77], rfOrder=76, authorNames=null, journalName=null, refType=null, unstructuredReference=GAO C C, LI G W, WANG T T, et al. Rhubarb extract relieves constipation by stimulating mucus production in the colon and altering the intestinal flora[J]. Biomedecine Pharmacother, 2021, 138: 111479., articleTitle=null, refAbstract=null), Reference(id=1319291608164577459, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[78], rfOrder=77, authorNames=null, journalName=null, refType=null, unstructuredReference=仲宗亮, 张盼盼, 金国泰, 等. 生大黄、清半夏、常山对大鼠脑-肠轴β-EP的影响及与升降浮沉的相关性[J]. 山东中医药大学学报, 2014, 38(2): 159-160, 167., articleTitle=null, refAbstract=null), Reference(id=1319291608231686324, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[79], rfOrder=78, authorNames=null, journalName=null, refType=null, unstructuredReference=GAO D M, ZHAO H Z, YIN Z H, et al. Rheum tanguticum alleviates cognitive impairment in APP/PS1 mice by regulating drug-responsive bacteria and their corresponding microbial metabolites[J]. Front Pharmacol, 2021, 12: 766120., articleTitle=null, refAbstract=null), Reference(id=1319291608294600885, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[80], rfOrder=79, authorNames=null, journalName=null, refType=null, unstructuredReference=LI Q Y, GUO Y, YU X H, et al. Protective mechanism of rhubarb anthraquinone glycosides in rats with cerebral ischaemia-reperfusion injury: interactions between medicine and intestinal flora[J]. Chin Med, 2020, 15: 60., articleTitle=null, refAbstract=null), Reference(id=1319291608353321142, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[81], rfOrder=80, authorNames=null, journalName=null, refType=null, unstructuredReference=GUO Y, LI Q Y, YU X H, et al. Rhubarb anthraquinone glycosides protect against cerebral ischemia-reperfusion injury in rats by regulating brain-gut neurotransmitters[J]. Biomed Chromatogr, 2021, 35(5): 50-58., articleTitle=null, refAbstract=null), Reference(id=1319291608420430007, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[82], rfOrder=81, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHANG T, YANG C, CHU J, et al. Emodin prevented depression in chronic unpredicted mild stress-exposed rats by targeting miR-139-5p/5-lipoxygenase[J]. Front Cell Dev Biol, 2021, 9: 696619., articleTitle=null, refAbstract=null), Reference(id=1319291608479150264, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[83], rfOrder=82, authorNames=null, journalName=null, refType=null, unstructuredReference=YANG Y P, JIANG Z J, ZHUGE D. Emodin attenuates lipopolysaccharide-induced injury via down-regulation of miR-223 in H9c2 cells[J]. Int Heart J, 2019, 60(2): 436-443., articleTitle=null, refAbstract=null), Reference(id=1319291608546259129, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[84], rfOrder=83, authorNames=null, journalName=null, refType=null, unstructuredReference=KASZKIN-BETTAG M, VENTSKOVSKIY B M, KRAVCHENKO A, et al. The special extract ERr 731 of the roots of Rheum rhaponticum decreases anxiety and improves health state and general well-being in perimenopausal women[J]. Menopause, 2007, 14(2): 270-283., articleTitle=null, refAbstract=null), Reference(id=1319291608613367994, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[85], rfOrder=84, authorNames=null, journalName=null, refType=null, unstructuredReference=DUBEY V P, SUREJA V P, KHENI D B. Efficacy evaluation of standardized Rheum rhaponticum root extract (ERr 731^®) on symptoms of menopause: a systematic review and meta-analysis study[J]. J Biomed Res, 2024, 38(3): 278-286., articleTitle=null, refAbstract=null), Reference(id=1319291608680476859, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[86], rfOrder=85, authorNames=null, journalName=null, refType=null, unstructuredReference=KIM I G, KANG S C, KIM K C, et al. Screening of estrogenic and antiestrogenic activities from medicinal plants[J]. Environ Toxicol Pharmacol, 2008, 25(1): 75-82., articleTitle=null, refAbstract=null), Reference(id=1319291608755974332, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[87], rfOrder=86, authorNames=null, journalName=null, refType=null, unstructuredReference=PARK S, KIM Y N, KWAK H J, et al. Estrogenic activity of constituents from the rhizomes of Rheum undulatum Linné[J]. Bioorg Med Chem Lett, 2018, 28(4): 552-557., articleTitle=null, refAbstract=null), Reference(id=1319291608823083197, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[88], rfOrder=87, authorNames=null, journalName=null, refType=null, unstructuredReference=方迎艳. 青年去势大鼠脑损伤的蛋白组基础及大黄素的脑保护机制[D]. 武汉: 华中科技大学, 2018., articleTitle=null, refAbstract=null), Reference(id=1319291608890192062, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[89], rfOrder=88, authorNames=null, journalName=null, refType=null, unstructuredReference=USUI T, IKEDA Y, TAGAMI T, et al. The phytochemical lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors[J]. J Endocrinol 2002, 175(2): 289-296., articleTitle=null, refAbstract=null), Reference(id=1319291608948912319, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[90], rfOrder=89, authorNames=null, journalName=null, refType=null, unstructuredReference=孙春晓, 黄嘉慧, 谯丽, 等. 大黄对MCAO模型大鼠的神经保护作用[J]. 中国药理学通报, 2021, 37(4): 584-589., articleTitle=null, refAbstract=null), Reference(id=1319291609020215488, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[91], rfOrder=90, authorNames=null, journalName=null, refType=null, unstructuredReference=MIZUNO M, KAWAMURA H, TAKEI N, et al. The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia[J]. J Neural Transm, 2008, 115(3): 521-530., articleTitle=null, refAbstract=null), Reference(id=1319291609091518657, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[92], rfOrder=91, authorNames=null, journalName=null, refType=null, unstructuredReference=律东, 林举达, 李明颖, 等. 79例精神分裂症患者血液内毒素分析[J]. 齐齐哈尔医学院学报, 2016, 37(24): 3000-3002., articleTitle=null, refAbstract=null), Reference(id=1319291609167016130, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[93], rfOrder=92, authorNames=null, journalName=null, refType=null, unstructuredReference=林萍, 金伟峰, 刘遵健, 等. 二胺氧化酶、D-乳酸和内毒素在抑郁障碍中的临床研究[J]. 国际检验医学杂志, 2019, 40(11): 1330-1332, 1336., articleTitle=null, refAbstract=null), Reference(id=1319291609234124995, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[94], rfOrder=93, authorNames=null, journalName=null, refType=null, unstructuredReference=杨桂林, 刘承统, 曾海生, 等. 生大黄与清蒸大黄的大承气汤对血清内毒素、NO和TNF-α含量变化的影响[J]. 湖北农业科学, 2021, 60(1): 96-99, 146., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319291598609952863, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, awardId=82374438, language=CN, fundingSource=国家自然科学基金项目(82374438), fundOrder=null, country=null), Fund(id=1319291598681256032, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291593895555123, awardId=国中医药人教函〔2022〕75号, language=CN, fundingSource=国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人教函〔2022〕75号), fundOrder=null, country=null), 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