中华中医药学刊

黄芩及其相关经典方剂治疗溃疡性结肠炎的研究进展

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陈綬林 ¹ , 张援 ² , 杨卓 ²

中华中医药学刊 | 国家项目点击 2026,44(8): 181-187

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中华中医药学刊 |国家项目点击 2026 , 44 (8) : 181 -187

黄芩及其相关经典方剂治疗溃疡性结肠炎的研究进展

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陈綬林¹, 张援², 杨卓²

作者信息

^1.辽宁中医药大学北部战区总医院研究生培养基地，辽宁　沈阳　110016

^2.北部战区总医院，辽宁　沈阳　110016

通讯作者:

杨卓（1975-），男，辽宁沈阳人，主任医师，硕士研究生导师，博士，研究方向：消化内科。E-mail：yangzhuocy@163.com。

作者简介:

陈綬林（2001-），女，河北邢台人，硕士在读，研究方向：中西医结合防治消化系统疾病。

Research Progress on Treatment of Ulcerative Colitis with Huangqin (Scutellaria Radix) and Its Related Classical Chinese Herbal Formula

Xulin CHEN¹, Yuan ZHANG², Zhuo YANG²

Affiliations

^1.Liaoning University of Traditional Chinese Medicine Postgraduate Training Base of General Hospital of Northern Theater Command, Shenyang 110016, Liaoning, China

^2.General Hospital of Northern Theater Command, Shenyang 110016, Liaoning, China

出版时间: 2026-08-10 doi: 10.13193/j.issn.1673-7717.2026.08.037

文章导航

摘要

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溃疡性结肠炎是一种以腹痛、黏液脓血便及里急后重为主要临床表现的肠道慢性非特异性炎症性疾病。该病发病机制复杂，尚未明确。西医治疗主要控制症状，缺乏特效药。中医在治疗溃疡性结肠炎上具有独特优势。黄芩为临床上治疗溃疡性结肠炎的常用中药之一，具有清热燥湿、泻火解毒、止血安胎的功效。目前研究发现黄芩及包含黄芩的经典方剂治疗效果显著。因此，就黄芩主要活性成分与相关方剂通过调控肠道菌群、修复肠道黏膜、调节免疫、抗炎抗氧化等相关机制进行阐述，期待能为溃疡性结肠炎的用药及后续研究提供思路与参考。

关键词

溃疡性结肠炎 / 黄芩 / 作用机制

Abstract

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Ulcerative colitis is a chronic non-specific inflammatory disease of the intestinal tract with abdominal pain, mucopurulent bloody stools, acute and severe symptoms as the main clinical manifestations. The pathogenesis of the disease is complex and has not been clarified. Western medicine treatment mainly controls the symptoms and lacks specific drugs. Traditional Chinese medicine has unique advantages in the treatment of ulcerative colitis. Huangqin (Scutellaria Radix) is one of the commonly used traditional Chinese medicines for the treatment of ulcerative colitis, which has the effects of clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding and tranquilizing the fetus. Current research has found that Huangqin (Scutellaria Radix) with classical Chinese medicine formulas have significant therapeutic effects. Therefore, this article described the mechanisms of Huangqin (Scutellaria Radix)-related traditional Chinese medicinal formulas by regulating intestinal flora, repairing intestinal mucosa, regulating immunity and anti-inflammatory and antioxidant effects, in the hope of providing ideas and references for the use of medication in ulcerative colitis and subsequent research.

Key words

ulcerative colitis / Huangqin (Scutellaria Radix) / mechanism of action

引用本文

陈綬林, 张援, 杨卓. 黄芩及其相关经典方剂治疗溃疡性结肠炎的研究进展. 中华中医药学刊, 2026 , 44 (8) : 181 -187 . DOI: 10.13193/j.issn.1673-7717.2026.08.037

Xulin CHEN, Yuan ZHANG, Zhuo YANG. Research Progress on Treatment of Ulcerative Colitis with Huangqin (Scutellaria Radix) and Its Related Classical Chinese Herbal Formula[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (8) : 181 -187 . DOI: 10.13193/j.issn.1673-7717.2026.08.037

基金

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国家自然科学基金青年科学基金项目(81802465)

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2026年第44卷第8期

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doi: 10.13193/j.issn.1673-7717.2026.08.037

首发时间：2026-10-20
出版时间：2026-08-10

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国家自然科学基金青年科学基金项目(81802465)

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^1.辽宁中医药大学北部战区总医院研究生培养基地，辽宁　沈阳　110016

^2.北部战区总医院，辽宁　沈阳　110016

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杨卓（1975-），男，辽宁沈阳人，主任医师，硕士研究生导师，博士，研究方向：消化内科。E-mail：yangzhuocy@163.com。

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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