Article(id=1319291429239771239, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291312826863771, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.08.047, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473187980, onlineDateStr=2026-10-20, pubDate=1786291200000, pubDateStr=2026-08-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473187980, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473187980, creator=13701087609, updateTime=1792473187980, updator=13701087609, issue=Issue{id=1319291312826863771, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='8', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1786291200000', pubDateStr='2026-08-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473160225, creator='13701087609', updateTime=1792473382588, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292245547799195, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291312826863771, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292245652656796, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291312826863771, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=229, endPage=232, ext={EN=ArticleExt(id=1319291429470457960, articleId=1319291429239771239, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Efficacy of Xiaoqinglong Decoction (小青龙汤) Combined with Inhalation Salmeterol Ticasone in Treatment of Children with Cold Asthma Complicated with Allergic Rhinitis and Its Influence on TCM Syndrome, FeNO and Lung Function, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the efficacy of Xiaoqinglong Decoction (小青龙汤) combined with inhalation salmeteroticasone in the treatment of children with cold asthma combined with allergic rhinitis and the effects on TCM syndromes, fractional exhaled nitric oxide (FeNO) and lung function.
Methods A total of 61 children with cold asthma combined with allergic rhinitis in the hospital from June 2022 to September 2023 were prospectively selected and divided into two groups according to random number table method, 30 patients in the control group were given conventional salmeterol ticasone treatment, and 31 patients in the observation group were given Xiaoqinglong Decoction combined with salmeterol ticasone treatment for 3 months. The therapeutic effects of the two groups were compared. The total nasal symptom scores (TNSS), childhood asthma control test (C-ACT), FeNO and TCM syndrome scores were compared between the two groups before and after treatment. The values of forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF) at the predicted value percentage were compared between the two groups. The adverse reactions in both groups were observed.
Results The observation group demonstrated a significantly higher total progress rate compared to the control group after treatment. Additionally, the TCM syndrome scores for nasal congestion, sneezing, wheezing and cough were lower in the observation group than those in the control group (P<0.05). After treatment, both groups experienced a decrease in TNSS scores and an increase in C-ACT levels. The observation group had a lower TNSS score and a higher C-ACT level than the control group. Furthermore, the observation group exhibited higher values for FVC, FEV1, FEV1/FVC and PEF, and a lower FeNO level compared to the control group (P<0.05). The overall incidence rate was lower in the observation group than that in the control group (P<0.05).
Conclusion Xiaoqinglong Decoction combined with inhalation salmeterol ticasone has a significant effect on the treatment of cold asthma combined with allergic rhinitis, improving lung function, reducing inflammation and reducing adverse reactions.
, authors=Xiaojuan XU, Shujun CAI, Mingrong CHAI, Zhichao XIE, authorsList=Xiaojuan XU, Shujun CAI, Mingrong CHAI, Zhichao XIE, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291429806002281, articleId=1319291429239771239, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=小青龙汤联合吸入沙美特罗替卡松治疗儿童寒性哮喘合并变应性鼻炎的疗效及对中医证候、FeNO、肺功能的影响, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探究小青龙汤联合吸入沙美特罗替卡松治疗儿童寒性哮喘合并变应性鼻炎的疗效及对中医证候、呼出气一氧化氮（fractional exhaled nitric oxide，FeNO）、肺功能的影响。
方法 前瞻性选取2022年6月—2023年9月收治的寒性哮喘合并变应性鼻炎患儿61例，按照随机数字表法分为两组，对照组30例给予常规沙美特罗替卡松治疗，观察组31例给予小青龙汤联合沙美特罗替卡松，治疗3个月，比较两组治疗效果；比较两组治疗前后鼻炎症状评分（total nasal symptom score，TNSS）、儿童哮喘控制测试评分（childhood asthma control test，C-ACT）、FeNO、中医证候积分变化；比较两组肺活量强制值（forced vital capacity，FVC）、一秒用力呼气容积（forced expiratory volume in one second，FEV1）、预测值百分比下的最大呼气流速（peak expiratory flow，PEF）；观察两组不良反应。
结果 治疗后，观察组总进步率显著高于对照组，观察组鼻塞、喷嚏、喘息、咳嗽中医证候积分均低于对照组（P<0.05）。治疗后，两组TNSS评分均降低，C-ACT均升高，且观察组TNSS评分低于对照组，C-ACT高于对照组，观察组FVC、FEV1、FEV1/FVC、PEF均高于对照组，FeNO低于对照组（P<0.05）。观察组总发生率低于对照组（P<0.05）。
结论 小青龙汤联合吸入沙美特罗替卡松治疗寒性哮喘合并变应性鼻炎的疗效显著，改善肺功能，减轻炎症反应，减少不良反应。
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徐小娟（1983-），女，广东东莞人，主治医师，硕士，研究方向：小儿内科。
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