Article(id=1319291308829687962, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.09.041, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473159272, onlineDateStr=2026-10-20, pubDate=1788969600000, pubDateStr=2026-09-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473159272, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473159272, creator=13701087609, updateTime=1792473159272, updator=13701087609, issue=Issue{id=1319291166823142311, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='9', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1788969600000', pubDateStr='2026-09-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792473125414, creator='13701087609', updateTime=1792473357559, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292140618896016, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292140618896017, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=224, endPage=227, ext={EN=ArticleExt(id=1319291309001654427, articleId=1319291308829687962, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Clinical Effect of Modified Huagnqi Jianzhong Decoction (黄芪建中汤加减) Combined with Acupuncture on Hp-positive Chronic Atrophic Gastritis, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the clinical effect of Modified Huagnqi Jianzhong Decoction (黄芪建中汤加减) combined with acupuncture on Helicobacter pylori (Hp)-positive chronic atrophic gastritis.
Methods A total of 60 patients with Hp-positive chronic atrophic gastritis admitted to the gastroenterology department of the hospital (admitted from January 2021 to January 2023) were divided into Western medicine treatment group and combined Chinese medicine group by random number table method, with 30 patients in each group. All patients in the Western medicine treatment group were treated with conventional western medicine therapy. The combined Chinese medicine was treated with Huangqi Jianzhong Decoction combined with acupuncture treatment on the basis of Western medicine treatment group. The Hp eradication rate and clinical therapeutic effect after treatment, as well as the changes of TCM syndrome scores such as continuous stomach pain, watery vomiting, warm hands and feet, fatigue and loose stool of the two groups before and after treatment, as well as the levels of inflammatory factors such as interleukin-1β (IL-1β) and interleukin-6 (IL-6), the level changes of serum somatostatin, gastrin and motilin, adverse reactions and disease recurrence rate 1 year after treatment were compared between the two groups.
Results The eradication rate of Hp in the combined Chinese medicine group (96.67%) was significantly higher than that in the western medicine group (76.67%) (P<0.05). The total effective rate of the combined Chinese medicine group (93.33%) was significantly higher than that of Western medicine group (73.33%) (P<0.05). Traditional Chinese medicine syndrome scores, inflammatory factor levels (IL-1β and IL-6), serum levels of somatostatin, gastrin and motilin were not significant before treatment in two groups (all P>0.05). After treatment, the scores of TCM symptoms such as continuous stomachache, watery vomiting, lukewarm hands and feet, fatigue and loose stool, as well as the levels of inflammatory factors (IL-1β and IL-6) were decreased in both groups, and the levels of serum somatostatin, gastrin and motilin were increased in both groups, and all indexes in the combined Chinese medicine group were better than those in the Western treatment group (P<0.05). The adverse reaction rate (3.33%) in the combined Chinese medicine group was lower than that in the western medicine treatment group (26.67%), and the recurrence rate one year after treatment (0.00%) was lower than that in the Western medicine treatment group (13.33%) (all P<0.05).
Conclusion Huagnqi Jianzhong Decoction combined with acupuncture has good clinical effect in the treatment of Hp-positive chronic atrophic gastritis, which can better relieve the symptoms, inhibit the inflammatory response of the body, improve the gastrointestinal function of the patients, with less adverse drug reactions and low disease recurrence rate one year after treatment, which is relatively safe and reliable.
, authors=Fan HE, Weiwei YU, Xiaojun ZHOU, Haixiao YE, authorsList=Fan HE, Weiwei YU, Xiaojun ZHOU, Haixiao YE, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291309278478492, articleId=1319291308829687962, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=黄芪建中汤加减联合针刺治疗Hp阳性慢性萎缩性胃炎临床效果观察, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探讨黄芪建中汤加减联合针刺治疗幽门螺杆菌（Hp）阳性慢性萎缩性胃炎临床效果。
方法 合计纳入医院消化内科收治的60例Hp阳性慢性萎缩性胃炎患者（2021年1月—2023年1月收治）以随机数字表法分成西医治疗组以及联合中医组，每组患者30例，西医治疗组患者均采取西医常规疗法治疗，联合中医组在西医治疗组治疗基础上联合黄芪建中汤加减联合针刺治疗，对比两组患者治疗后Hp根除率以及临床治疗效果、治疗前后两组患者胃痛绵绵、泛吐清水、手足不温、神疲乏力、大便多溏等中医证候积分变化以及白介素-1β（Interleukin-1 β，IL-1β）及白介素-6（interleukin 6，IL-6）等炎症因子水平变化、血清生长抑素及胃泌素、胃动素水平变化、不良反应情况及治疗后1年疾病复发率。
结果 联合中医组患者治疗后Hp根除率（96.67%）明显高于西医治疗组（76.67%），P<0.05；联合中医组临床治疗总有效率（93.33%）明显比西医治疗组总有效率（73.33%）更高，P<0.05；比较各组患者治疗前胃痛绵绵、泛吐清水、手足不温、神疲乏力、大便多溏等中医证候积分、炎症因子水平（IL-1β及IL-6）、血清生长抑素及胃泌素、胃动素水平，均P>0.05，各组治疗后胃痛绵绵、泛吐清水、手足不温、神疲乏力、大便多溏等中医证候积分、炎症因子水平（IL-1β及IL-6）等指标均下降，血清生长抑素及胃泌素、胃动素水平均提升，联合中医组治疗后各项指标均优于西医治疗组患者，均P<0.05；联合中医组不良反应率（3.33%）比西医治疗组（26.67%）更低，治疗后1年复发率（0.00%）比西医治疗组（13.33%）更低，均P<0.05。
结论 黄芪建中汤加减联合针刺治疗幽门螺杆菌（Hp）阳性慢性萎缩性胃炎临床效果良好，可较好改善患者病症及抑制机体炎症反应，改善患者胃肠功能，用药不良反应少，治疗后1年疾病复发率低，较为安全可靠。
, authors=何璠, 余维微, 周晓君, 叶海潇, authorsList=何璠, 余维微, 周晓君, 叶海潇, authorCompany=null, correspAuthors=null, authorNote=
何璠（1988-），女，江西九江人，副主任中医师，硕士，研究方向：中医脾胃病。
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