Article(id=1319291252399526455, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.09.023, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473145817, onlineDateStr=2026-10-20, pubDate=1788969600000, pubDateStr=2026-09-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473145817, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473145817, creator=13701087609, updateTime=1792473145817, updator=13701087609, issue=Issue{id=1319291166823142311, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='9', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1788969600000', pubDateStr='2026-09-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792473125414, creator='13701087609', updateTime=1792473357559, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292140618896016, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292140618896017, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=124, endPage=128, ext={EN=ArticleExt(id=1319291252592464440, articleId=1319291252399526455, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effects of Xuanfei Tongluo Pingchuan Decoction (宣肺通络平喘汤) Combined with Seretide on Clinical Symptoms and Blood IgE and EOS Counts in Treatment of Patients with Chest Tightness Variant Asthma, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the effects of Xuanfei Tongluo Pingchuan Decoction (宣肺通络平喘汤) combined with Seretide on clinical symptoms and blood immunoglobulin E (IgE) and eosinophil (EOS) counts in the patients with chest tightness variant asthma (CTVA).
Methods One hundred and fifty-two patients with CTVA who attended the respiratory department of the hospital from July 2022 to June 2024 were selected and randomly divided into the single-drug group (76 cases) and the combination group (76 cases). The single-drug group was given seretide inhalation treatment, and the combined group added Xuanfei Tongluo Pingchuan Decoction on the basis of the single-drug group. The efficacy, revised asthma control questionnaire (r-ACQ) score, clinical symptom scores, pulmonary function indexes, blood IgE and EOS counts and adverse reactions were observed in the two groups.
Results The total clinical effectiveness rate in the combination group was 94.74% (72/76), higher than that [82.89% (63/76)] in the single-drug group (χ2=5.365, P<0.05). After treatment, r-ACQ scores and clinical symptom scores such as chest tightness, shortness of breath, cough and sputum were reduced in both groups (P<0.05), and the scores of the combination group were lower than those of the single-drug group (P<0.05). The levels of percentage of estimated forced expiratory volume in the first second (FEV1%) and peak expiratory flow (PEF) were increased in both groups (P<0.05), and the levels of the combination group were higher than those of the single-drug group (P<0.05). IgE levels and EOS counts were reduced in both groups after treatment, and the results of the combination group were lower than those of the single-drug group (P<0.05). The incidence of adverse reactions of two groups had no statistical difference (P>0.05).
Conclusion The combination of Xuanfei Tongluo Pingchuan Decoction and seretide can significantly improve the clinical efficacy of the CTVA patients, improve the clinical symptoms and lung function and reduce the blood IgE and EOS counts, with a good safety profile.
, authors=Tong LIU
1, Wei XIA
2, Minqing LIU
1, Zongwei LIU
1, Ning LIU
1, Xiuyan SHI
1, authorsList=Tong LIU, Wei XIA, Minqing LIU, Zongwei LIU, Ning LIU, Xiuyan SHI, authorCompany=null, correspAuthors=Ning LIU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291252948980281, articleId=1319291252399526455, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=宣肺通络平喘汤联合舒利迭对胸闷变异性哮喘症状及血IgE、EOS计数影响, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的 探讨宣肺通络平喘汤联合舒利迭（沙美特罗替卡松）对胸闷变异性哮喘（chest tightness variant asthma，CTVA）患者临床症状及血免疫球蛋白E（Immunoglobulin E，IgE）、嗜酸性粒细胞（eosinophil count，EOS）计数的影响。
方法 选取2022年7月—2024年6月于医院呼吸科就诊的CTVA患者152例，随机分为单药组（76例）和联合组（76例）。单药组给予舒利迭吸入治疗，联合组在单药组基础上加用宣肺通络平喘汤。观察两组的疗效、修订版哮喘控制问卷（revised asthma control questionnaire，r-ACQ）评分、临床症状积分、肺功能指标、血IgE和EOS计数及不良反应。
结果 联合组患者的临床总有效率94.74%（72/76）高于单药组82.89%（63/76）（χ2=5.365，P<0.05）。治疗后，两组r-ACQ评分和临床症状积分均降低（P<0.05），且联合组低于单药组（P<0.05）。两组第一秒用力呼气容积预计值占百分比（percentage of estimated forced expiratory volume in the first second，FEV1%）及呼气流量峰值（peak expiratory flow，PEF）均提高（P<0.05），且联合组高于单药组（P<0.05）；两组治疗后IgE水平和EOS计数均降低，且联合组低于单药组（P<0.05）。两组不良反应发生率差异无统计学意义（P>0.05）。
结论 宣肺通络平喘汤联合舒利迭可显著提高CTVA患者临床疗效，改善临床症状和肺功能，降低血IgE和EOS计数，且安全性良好。
, authors=刘通
1, 夏伟
2, 刘敏青
1, 刘宗伟
1, 刘宁
1, 石岫岩
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刘通（1989-），男，江苏东海人，主治中医师，硕士，研究方向：呼吸系统疾病。
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