Article(id=1319291205008077569, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.09.015, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473134518, onlineDateStr=2026-10-20, pubDate=1788969600000, pubDateStr=2026-09-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473134518, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473134518, creator=13701087609, updateTime=1792473134518, updator=13701087609, issue=Issue{id=1319291166823142311, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='9', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1788969600000', pubDateStr='2026-09-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792473125414, creator='13701087609', updateTime=1792473357559, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292140618896016, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292140618896017, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=81, endPage=85, ext={EN=ArticleExt(id=1319291207482716930, articleId=1319291205008077569, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress on Mechanism of Sanqi (Panax notoginseng) Saponins in Treatment of Osteoporosis, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Osteoporosis (OP) is a systemic metabolic bone disease that causes bone loss over time and increases the risk of fracture, severely affecting patients' quality of life. However, there is still a lack of effective and safe targeted drugs. In recent years, some natural compounds have been favored by scholars due to their significant advantages of fewer adverse effects, obvious therapeutic effects and low economic costs. Sanqi (Panax notoginseng) saponins, an active ingredient of Sanqi (Panax notoginseng), a traditional medicinal plant, was found to be able to regulating various related signaling pathways such as mitogen-activated protein kinase (MAPK), Wnt/β-catenin, transforming growth factor β1 (TGF-β1)/Smads and RhoA/ROCK, Sanqi (Panax notoginseng) saponins can also control OP progression by regulating angiogenesis and lipid metabolism, promoting bone formation and inhibiting bone loss, and it is expected to be a potential therapeutic strategy for OP. Based on this, the authors briefly described the basic features of Sanqi (Panax notoginseng) saponins, and at the same time, the above mechanisms were specifically sorted out and elaborated, with a view to providing ideas and strategies for further research and treatment of Sanqi (Panax notoginseng) total saponins in the treatment of OP.

, authors=Peng WANG¹, Longcan LI², Fayan WEN², Xingwen XIE³, Yanjun ZHANG¹, authorsList=Peng WANG, Longcan LI, Fayan WEN, Xingwen XIE, Yanjun ZHANG, authorCompany=null, correspAuthors=Yanjun ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291207864398595, articleId=1319291205008077569, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=三七总皂苷治疗骨质疏松症的机制研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

骨质疏松症（Osteoporosis，OP）是一种全身性代谢性骨骼疾病，随着时间推移会导致骨质流失并增加骨折的风险，严重影响患者的生活质量。然而目前仍缺乏有效且安全的靶向药物。近年来，一些天然化合物因其不良反应少、治疗效果明显且经济成本低的显著优势而广受学者们的青睐。三七总皂苷是传统药用植物三七的一种活性成分，通过回顾国内外的已有成果，发现三七总皂苷能够通过调控丝裂原活化蛋白激酶（MAPK）、Wnt/β-catenin、转化生长因子β-1（TGF-β1）/Smads以及RhoA/ROCK等多种相关信号通路，还能通过调节血管生成和脂肪代谢，促进骨形成，抑制骨流失，控制OP进展，有望成为OP的潜在治疗策略。基于此，对三七总皂苷的基本特征进行简述，同时将上述机制进行具体梳理和阐述，以期为三七总皂苷治疗OP的进一步研究治疗提供思路和策略。

, authors=王鹏¹, 李茏灿², 温发延², 谢兴文³, 张彦军¹, authorsList=王鹏, 李茏灿, 温发延, 谢兴文, 张彦军, authorCompany=null, correspAuthors=张彦军, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=uzphmXfscljR1vGc77OWqw==, magXml=6a2HbSVgzOFD6NIlj99IDA==, pdfUrl=null, pdf=gei+TOAVCrNSrqSS1g1gNw==, pdfFileSize=1630746, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=lMWNv6JUmu0uC7Bx6uKa6w==, mapNumber=null, fund=null)}, authors=[Author(id=1319291208338354958, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291205008077569, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291208409658128, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291205008077569, authorId=1319291208338354958, language=EN, stringName=Peng WANG, firstName=Peng, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291208472572689, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291205008077569, authorId=1319291208338354958, language=CN, stringName=王鹏, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.甘肃省中医院，甘肃　兰州　730050, bio={"content":"

王鹏（1986-），男，山西阳泉人，主治医师，研究方向：骨伤科疾病的中西医结合诊疗。

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王鹏（1986-），男，山西阳泉人，主治医师，研究方向：骨伤科疾病的中西医结合诊疗。

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