Article(id=1317133146039112406, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.01.035, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791958613165, onlineDateStr=2026-10-14, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791958613165, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791958613165, creator=13701087609, updateTime=1791958613165, updator=13701087609, issue=Issue{id=1317133098966433889, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='1', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791958601943, creator='13701087609', updateTime=1791958824557, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317134032719171723, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317134032719171724, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=175, endPage=186, ext={EN=ArticleExt(id=1317133146261410519, articleId=1317133146039112406, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Comparative Analysis of Serum Pharmacochemistry of Nyuzhenzi（Ligustri Lucidi Fructus）Before and After Wine Steaming Based on UPLC-Orbitrap Fusion Lumos Tribrid-MS, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective Based on ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry（UPLC-Orbitrap Fusion Lumos Tribrid-MS），the migration components in serum of rats after intragastric administration of water extract from Nyuzhenzi（Ligustri Lucidi Fructus，LLF）and wine steamed Nyuzhenzi（Ligustri Lucidi Fructus）（WLLF）were compared and analyzed.
Methods Male SD rats were randomly divided into blank group，LLF group（10.8 g·kg-1·d-1）and WLLF group（10.8 g·kg-1·d-1），with 6 rats in each group. The administration groups were given the water extract of LLF and WLLF，respectively，and the blank group was given the equal volume of purified water，once in the morning and once in the evening，for 5 consecutive days. One hour after the last administration，the blood was taken from the abdominal aorta to prepare the serum samples. AccucoreTM C18（100mm×2.1mm，2.6μm）chromatographic column was used. The mobile phase was acetonitrile（A）-0.1% formic acid water（B），with the gradient elution（0-5 min，95% B→85% B；5-10 min，85% B→73% B；10-24 min，73% B→15% B）. The flow rate was 0.2 mL·min-1. The injection volume was 5 μL. The positive and negative ion mode scanning was used，with the scanning range of m/z 120-1200. Compound Discoverer 3.3 software was used to analyze and identify the prototype components and metabolites of LLF and WLLF into blood according to mass spectrometry data and related literature. The multivariate statistical analysis method was used to compare the different components between the medicated serum of LLF and WLLF.
Results A total of 64 blood components were identified in the serum of rats given the water extract of LLF，including 40 prototype components and 24 metabolites. A total of 57 blood components were identified in the serum of rats given the water extract of WLLF including 35 prototype components and 22 metabolites. The prototype components mainly included phenylethanoid glycosides，iridoids，triterpenoids，flavonoids，etc. The metabolic pathways mainly included hydroxylation，methylation，glucuronidation，etc. According to the variable importance in projection（VIP）value>1，student's t test results were not significant（P<0.05），12 differential blood components such as specnuezhenide and ligustrosidic acid were screened，including 7 prototype components and 5 metabolites.
Conclusion The serum migration components of LLF changed significantly after wine steaming，which could provide a theoretical basis for elucidating the material basis of LLF and WLLF.
, authors=Haolin LIU
1, 2, Lishi ZHENG
1, 2, 3, Shuding SUN
1, 2, 3, Di ZHAO
1, 2, 3, Huanru LI
1, 2, Suxiang FENG
1, 2, 3, authorsList=Haolin LIU, Lishi ZHENG, Shuding SUN, Di ZHAO, Huanru LI, Suxiang FENG, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317133146605343448, articleId=1317133146039112406, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=基于UPLC-Orbitrap Fusion Lumos Tribrid-MS的女贞子酒蒸前后血清药物化学对比分析, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的 基于超高效液相色谱-四极杆-静电场轨道阱-线性离子阱质谱法（ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry，UPLC-Orbitrap Fusion Lumos Tribrid-MS）对大鼠灌胃女贞子、酒女贞子水提液后血清中的移行成分进行对比分析。
方法 雄性Sprague-Dawley（SD）大鼠随机分为空白组、女贞子组（10.8 g·kg-1·d-1）和酒女贞子组（10.8 g·kg-1·d-1），每组6只，给药组分别灌胃给予女贞子、酒女贞子水提液，空白组灌胃等体积纯净水，早晚各1次，连续5 d，末次给药1 h后腹主动脉取血，制备血清样品。采用AccucoreTM C18（100 mm×2.1 mm，2.6 μm）色谱柱，流动相为乙腈（A）-0.1%甲酸水（B），梯度洗脱（0～5 min，95% B→85%B；5～10 min，85%B→73%B；10～24 min，73%B→15%B），流速0.2 mL·min-1，进样量5μL，正、负离子模式扫描，扫描范围m/z 120～1200。采用Compound Discoverer 3.3软件，根据质谱数据和相关文献对女贞子、酒女贞子入血原型成分和代谢产物进行分析鉴定；采用多元统计分析方法对比女贞子、酒女贞子含药血清间的差异性成分。
结果 在给予女贞子水提液大鼠血清中共鉴定得到64个入血成分，包括40个原型成分和24个代谢产物；在给予酒女贞子水提液大鼠血清中共鉴定得到57个入血成分，包括35个原型成分和22个代谢产物。原型成分主要包括苯乙醇苷类、环烯醚萜类、三萜类、黄酮类等，代谢途径主要包括羟基化、甲基化、葡萄糖醛酸化等。根据变量重要性投影（variable importance in projection，VIP）值>1，t检验（Student's t test）结果P<0.05筛选出特女贞苷、女贞苷酸等12个差异性入血成分，其中7个原型成分、5个代谢产物。
结论 女贞子酒蒸后血清移行成分发生明显改变，可为阐明女贞子、酒女贞子药效物质基础提供理论依据。
, authors=刘昊霖
1, 2, 郑历史
1, 2, 3, 孙淑仃
1, 2, 3, 赵迪
1, 2, 3, 李焕茹
1, 2, 冯素香
1, 2, 3, authorsList=刘昊霖, 郑历史, 孙淑仃, 赵迪, 李焕茹, 冯素香, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=vxfOSrajEUCY+iVNczhGhg==, magXml=Re04gm42HKnXvN9e5mSOZQ==, pdfUrl=null, pdf=CLaC62s9qie1ULhOPf9oqg==, pdfFileSize=3596743, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=3B3tS3K6JzYZhL4INNJVYw==, mapNumber=null, fund=null)}, authors=[Author(id=1319724697688855035, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724697785324030, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724697688855035, language=EN, stringName=Haolin LIU, firstName=Haolin, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724697869210111, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724697688855035, language=CN, stringName=刘昊霖, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)])]), Author(id=1319724697957290497, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724698062148101, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724697957290497, language=EN, stringName=Lishi ZHENG, firstName=Lishi, middleName=null, lastName=ZHENG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724698192171526, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724697957290497, language=CN, stringName=郑历史, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)]), AuthorCompany(id=1319724697575608823, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=3., ext=[AuthorCompanyExt(id=1319724697588191736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724697600774649, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046)])]), Author(id=1319724698255086088, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724698351555084, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698255086088, language=EN, stringName=Shuding SUN, firstName=Shuding, middleName=null, lastName=SUN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724698414469645, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698255086088, language=CN, stringName=孙淑仃, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)]), AuthorCompany(id=1319724697575608823, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=3., ext=[AuthorCompanyExt(id=1319724697588191736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724697600774649, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046)])]), Author(id=1319724698515132943, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724698624184851, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698515132943, language=EN, stringName=Di ZHAO, firstName=Di, middleName=null, lastName=ZHAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724698703876628, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698515132943, language=CN, stringName=赵迪, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)]), AuthorCompany(id=1319724697575608823, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=3., ext=[AuthorCompanyExt(id=1319724697588191736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724697600774649, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046)])]), Author(id=1319724698779374102, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724698867454489, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698779374102, language=EN, stringName=Huanru LI, firstName=Huanru, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724698926174746, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698779374102, language=CN, stringName=李焕茹, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)])]), Author(id=1319724698997477916, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724699098141216, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698997477916, language=EN, stringName=Suxiang FENG, firstName=Suxiang, middleName=null, lastName=FENG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724699173638689, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, authorId=1319724698997477916, language=CN, stringName=冯素香, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, 3, address=
1.河南中医药大学，河南郑州 450046
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)]), AuthorCompany(id=1319724697575608823, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=3., ext=[AuthorCompanyExt(id=1319724697588191736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724697600774649, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046)])])], keywords=[Keyword(id=1319724699328827938, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=EN, orderNo=1, keyword=Nyuzhenzi（Ligustri Lucidi Fructus）), Keyword(id=1319724699395936803, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=EN, orderNo=2, keyword=processing), Keyword(id=1319724699475628580, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=EN, orderNo=3, keyword=serum pharmacochemistry), Keyword(id=1319724699538543141, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=EN, orderNo=4, keyword=UPLC-Orbitrap Fusion Lumos Tribrid-MS), Keyword(id=1319724699618234918, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=EN, orderNo=5, keyword=multivariate statistical analysis), Keyword(id=1319724699693732391, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=CN, orderNo=1, keyword=女贞子), Keyword(id=1319724699760841256, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=CN, orderNo=2, keyword=炮制), Keyword(id=1319724699827950121, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=CN, orderNo=3, keyword=血清药物化学), Keyword(id=1319724699890864682, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=CN, orderNo=4, keyword=UPLC-Orbitrap Fusion Lumos Tribrid-MS), Keyword(id=1319724699962167851, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, language=CN, orderNo=5, keyword=多元统计分析)], refs=[Reference(id=1319724700054442540, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［1］, rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=李焕茹，冯志毅，赵迪，等.基于多元统计分析的酒制前后女贞子成分差异分析［J］.天然产物研究与开发，2022，34（1）：102-113., articleTitle=null, refAbstract=null), Reference(id=1319724700113162797, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［2］, rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=徐浩然，程国良，黄志伟，等.女贞药用价值及其相关上市药品的研究进展［J］.中草药，2023，54（5）：1663-1671., articleTitle=null, refAbstract=null), Reference(id=1319724700197048878, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［3］, rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=刘美红，邹峥嵘.女贞子化学成分、药理作用及药动学研究进展［J］.热带亚热带植物学报，2022，30（3）：446-460., articleTitle=null, refAbstract=null), Reference(id=1319724700268352047, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［4］, rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=杜鹏飞，盛韵脂，王君涛，等.女贞子活性成分代谢特征及药理作用研究进展［J］.化学试剂，2024，46（9）：117-125., articleTitle=null, refAbstract=null), Reference(id=1319724700331266608, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［5］, rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=肖建鹏.基于网络药理学和PK-PD结合模型阐释酒女贞子抗骨质疏松增效机理［D］.镇江：江苏大学，2022., articleTitle=null, refAbstract=null), Reference(id=1319724700394181169, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［6］, rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=阿曼古丽·阿不都克热木，马丽.中药治疗糖尿病肾病的研究进展［J］.新疆中医药，2020，38（6）：77-80., articleTitle=null, refAbstract=null), Reference(id=1319724702063514162, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［7］, rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=刘仁慧，郭忻.淫羊藿女贞子配伍对哮喘大鼠模型Th1/Th2调节作用的研究［J］.中华中医药学刊，2009，27（11）：2288-2291., articleTitle=null, refAbstract=null), Reference(id=1319724702139011635, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［8］, rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=曹瑞，邓翀，马露露.响应面法优化酒蒸女贞子饮片炮制工艺［J］.中医药导报，2019，25（19）：66-70., articleTitle=null, refAbstract=null), Reference(id=1319724702214509108, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［9］, rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=薛青苹，张丽君，郭志俊，等.不同蒸、炖工艺的酒女贞子外观性状和主成分比较［J］.中南农业科技，2024，45（2）：46-50., articleTitle=null, refAbstract=null), Reference(id=1319724702285812277, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［10］, rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=魏玉，石延榜，王彬，等.基于层次分析法和多指标正交试验优选黑豆汁蒸女贞子炮制工艺［J］.时珍国医国药，2024，35（5）：1160-1163., articleTitle=null, refAbstract=null), Reference(id=1319724702378086966, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［11］, rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=徐文娟，董海鹏，韩婷，等.蒸制工艺对酒女贞子外观性状和主要成分的影响［J］.中国现代中药，2021，23（8）：1437-1443., articleTitle=null, refAbstract=null), Reference(id=1319724702461973047, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［12］, rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=李焕茹，朱泓锦，冯志毅，等.女贞子及不同炮制品指纹图谱对比研究［J］.中药材，2022，45（7）：1601-1605., articleTitle=null, refAbstract=null), Reference(id=1319724702554247736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［13］, rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=张建伟，刘伟，沈沁，等.基于UPLC-Q-Orbitrap-MS的鹿角方化学成分及组织分布分析［J］.中国实验方剂学杂志，2024，30（8）：148-156., articleTitle=null, refAbstract=null), Reference(id=1319724702625550905, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［14］, rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=张瀚水，龚本义，南敏伦，等.UPLC-Q Exactive Plus-MS分析高粱壳化学成分及黄嘌呤氧化酶体外抑制活性筛选［J］.应用化学，2023，40（11）：1587-1594., articleTitle=null, refAbstract=null), Reference(id=1319724702696854074, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［15］, rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=曹辉，周霖，孙志，等.基于UHPLC-Q-Orbitrap HRMS结合整合网络药理学的藤黄健骨胶囊化学成分识别及作用机制初步研究［J］.中草药，2020，51（9）：2408-2417., articleTitle=null, refAbstract=null), Reference(id=1319724702763962939, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［16］, rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=史静超，裴科，张维钲，等.基于UPLC-QE-Orbitrap-MS法的芪蛭降糖胶囊血清药物化学研究［J］.中成药，2023，45（7）：2414-2419., articleTitle=null, refAbstract=null), Reference(id=1319724702860431932, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［17］, rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=HAN X，WANG S，YANG X X，et al. Analysis of plasma migration components in
Patrinia villosa（Thunb.）Juss. effective parts by UPLC-Q-TOF-MS［J］. Biomed Chromatogr，2020，34（1）：e4701., articleTitle=null, refAbstract=null), Reference(id=1319724702927540797, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［18］, rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=庄梓鸣，李钦青，蔡梅超，等.基于TGF-β1/Smads通路探讨女贞子酒蒸前后治疗糖尿病肾纤维化的作用机制［J］.时珍国医国药，2024，35（6）：1394-1398., articleTitle=null, refAbstract=null), Reference(id=1319724703003038270, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［19］, rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=蒋云秀，曹马怡洁，吴杰，等.基于HPLC指纹图谱结合多元统计分析九制女贞子炮制过程中成分变化［J］.中华中医药学刊，2024，42（7）：250-254，285-286., articleTitle=null, refAbstract=null), Reference(id=1319724703065952831, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［20］, rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=陈烨，刘彤彤，吴怡，等.特女贞苷对MC3T3-E1细胞氧化损伤的保护作用及相关通路研究［J］.中兽医医药杂志，2023，42（2）：1-5., articleTitle=null, refAbstract=null), Reference(id=1319724703149838912, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［21］, rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=姜晓旭，孙慕涵，张渤旭，等.特女贞苷对脂多糖诱导的巨噬细胞促炎反应的抑制作用及机制［J］.癌变·畸变·突变，2023，35（4）：245-252., articleTitle=null, refAbstract=null), Reference(id=1319724703229530689, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［22］, rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=CAO K，XU J，ZOU X，et al. Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice［J］. Free Radic Biol Med，2014，67：396-407., articleTitle=null, refAbstract=null), Reference(id=1319724703317611074, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［23］, rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=CETRULLO S，D’ADAMO S，GUIDOTTI S，et al. Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and-independent mechanisms［J］. Biochim Biophys Acta，2016，1860（6）：1181-1191., articleTitle=null, refAbstract=null), Reference(id=1319724703414080067, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［24］, rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=罗成，陈明智，李艳.羟基酪醇的药理作用研究进展［J］.中国药学杂志，2019，54（20）：1642-1646., articleTitle=null, refAbstract=null), Reference(id=1319724703476994628, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［25］, rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=CAO S S，WASTNEY M E，LACHCIK P J，et al. Both oleanolic acid and a mixture of oleanolic and ursolic acids mimic the effects of fructus ligustri lucidi on bone properties and circulating 1，25-dihydroxycholecalciferol in ovariectomized rats［J］. J Nutr，2018，148（12）：1895-1902., articleTitle=null, refAbstract=null), Reference(id=1319724703544103493, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［26］, rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=李德成，刘庆燕.女贞子化学成分和药理作用的研究进展［J］.当代医药论丛，2019，17（14）：33-34., articleTitle=null, refAbstract=null), Reference(id=1319724703627989574, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［27］, rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=周剑宁，欧阳明安.药用女贞属植物化学成分的研究进展［J］.天然产物研究与开发，2003（1）：77-86., articleTitle=null, refAbstract=null), Reference(id=1319724703707681351, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［28］, rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=刘亭亭，王萌.女贞子化学成分与药理作用研究进展［J］.中国实验方剂学杂志，2014，20（14）：228-234., articleTitle=null, refAbstract=null), Reference(id=1319724703770595912, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［29］, rfOrder=28, authorNames=null, journalName=null, refType=null, unstructuredReference=袁毅，沈丽新，潘燕.女贞子对2型糖尿病大鼠胰岛β细胞的作用及机制［J］.中华中医药学刊，2019，37（1）：206-208，264., articleTitle=null, refAbstract=null), Reference(id=1319724703829316169, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［30］, rfOrder=29, authorNames=null, journalName=null, refType=null, unstructuredReference=黄永湘，李强，李宝林，等.红景天苷激活PI3K/AKT通路改善绝经后骨质疏松症实验研究［J］.中国骨质疏松杂志，2021，27（8）：1135-1139，1146., articleTitle=null, refAbstract=null), Reference(id=1319724703909007946, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［31］, rfOrder=30, authorNames=null, journalName=null, refType=null, unstructuredReference=张申尧，董克芳，王凡.红景天苷抵抗骨细胞凋亡的作用和对绝经后骨质疏松患者的影响［J］.中国临床药理学杂志，2020，36（22）：3624-3629., articleTitle=null, refAbstract=null), Reference(id=1319724703976116811, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［32］, rfOrder=31, authorNames=null, journalName=null, refType=null, unstructuredReference=何丹丹，赵白秀，汪华君，等.女贞子中主要活性成分红景天苷和特女贞苷的逆转铁过载促进骨形成相互作用研究［J］.中国骨质疏松杂志，2024，30（1）：70-74，92., articleTitle=null, refAbstract=null), Reference(id=1319724704039031372, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［33］, rfOrder=32, authorNames=null, journalName=null, refType=null, unstructuredReference=刘佳.女贞子免疫增强活性成分分离鉴定及作用机制研究［D］.杨凌：西北农林科技大学，2021., articleTitle=null, refAbstract=null), Reference(id=1319724704118723149, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［34］, rfOrder=33, authorNames=null, journalName=null, refType=null, unstructuredReference=李胜.羟基酪醇的分离纯化、药效学及其绝对生物利用度研究［D］.天津：天津中医药大学，2023., articleTitle=null, refAbstract=null), Reference(id=1319724704185832014, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［35］, rfOrder=34, authorNames=null, journalName=null, refType=null, unstructuredReference=郭卫平，鲁绪，褚泽军，等.橄榄苦苷提取工艺及生物活性研究进展［J］.食品与机械，2023，39（10）：233-240., articleTitle=null, refAbstract=null)], funds=null, companyList=[AuthorCompany(id=1319724695805612529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=1., ext=[AuthorCompanyExt(id=1319724695814001138, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695826584051, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695805612529, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1.河南中医药大学，河南郑州 450046)]), AuthorCompany(id=1319724695910470132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=2., ext=[AuthorCompanyExt(id=1319724695918858741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases co-constructed by Henan Province & Education Ministry of P. R., Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724695927247350, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724695910470132, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2.呼吸疾病中医药防治省部共建协同创新中心，河南郑州 450046)]), AuthorCompany(id=1319724697575608823, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, xref=3., ext=[AuthorCompanyExt(id=1319724697588191736, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.Henan Engineering Research Center of Modern Chinese Medicine Research, Development and Application, Zhengzhou 450046, Henan, China), AuthorCompanyExt(id=1319724697600774649, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317133146039112406, companyId=1319724697575608823, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3.河南省现代中药研发与应用工程研究中心，河南郑州 450046)])], figs=null, attaches=null, journal=Journal(id=1255846881855815682, delFlag=0, nameCn=中华中医药学刊, nameEn=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1673-7717, eissn=null, cn=21-1546/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=v4T+dd+NLAnioIpGAbkcEQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Archives of Traditional Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1777346829146, updatedTime=1788949222391, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=v4T+dd+NLAnioIpGAbkcEQ==, picEn=RAy5vuC40hwJB+Y0pEARug==, jcr=null, cjcr=null, exts=[JournalExt(id=1304510846391050374, language=CN, name=中华中医药学刊, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222419, updatedTime=1788949222419, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304510846449770631, language=EN, name=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222433, updatedTime=1788949222433, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1255847919539208197, websiteList=[Website(id=1255847989868900719, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN, language=CN, createTime=1777347093312, createBy=18614031015, updateTime=1777347427646, updateBy=18614031015, name=中华中医药学刊-中文, tplId=1146099689490845704, title=中华中医药学刊, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849512594170105, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=articleTextType, value=kx, createTime=1777347456358, updateTime=1777347456358, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512564809974, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=banner, value=null, createTime=1777347456352, updateTime=1777347456352, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512631918844, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=grayFlag, value=0, createTime=1777347456367, updateTime=1777347456367, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512552227061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347456348, updateTime=1777347456348, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512657084670, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=minRunFlag, value=0, createTime=1777347456373, updateTime=1777347456373, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512589975800, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic, createTime=1777347456357, updateTime=1777347456357, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512648696061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=silenceFlag, value=0, createTime=1777347456371, updateTime=1777347456371, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512581587191, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1777347456355, updateTime=1777347456355, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512619335930, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeColor, value=null, createTime=1777347456364, updateTime=1777347456364, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512627724539, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeStyle, value=null, createTime=1777347456366, updateTime=1777347456366, creator=18614031015, updator=18614031015)]), Website(id=1255847989944398211, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN, language=EN, createTime=1777347093330, createBy=18614031015, updateTime=1777347417860, updateBy=18614031015, name=中华中医药学刊-英文, tplId=1146101810881728533, title=Chinese Archives of Traditional Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849538993119491, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=articleTextType, value=kx, createTime=1777347462652, updateTime=1777347462652, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538972147968, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=banner, value=null, createTime=1777347462647, updateTime=1777347462647, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539047645446, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=grayFlag, value=0, createTime=1777347462665, updateTime=1777347462665, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538930204927, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347462637, updateTime=1777347462637, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539064422664, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=minRunFlag, value=0, createTime=1777347462669, updateTime=1777347462669, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538988925186, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic, createTime=1777347462651, updateTime=1777347462651, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539060228359, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=silenceFlag, value=0, createTime=1777347462668, updateTime=1777347462668, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538980536577, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1777347462649, updateTime=1777347462649, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539001508100, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeColor, value=null, createTime=1777347462654, updateTime=1777347462654, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539039256837, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeStyle, value=null, createTime=1777347462663, updateTime=1777347462663, creator=18614031015, updator=18614031015)])], journalTitle=中华中医药学刊, weixinUrl=null, journalUrl=https://castjournals.cast.org.cn/zhzyyxk, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Archives of Traditional Chinese Medicine, journalPhotoCn=v4T+dd+NLAnioIpGAbkcEQ==, journalPhotoEn=RAy5vuC40hwJB+Y0pEARug==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2026.01.035, detailUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2026.01.035, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/PDF/10.13193/j.issn.1673-7717.2026.01.035, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/PDF/10.13193/j.issn.1673-7717.2026.01.035, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1767974400000, fullTextJson=null, articleText=null, reference=null)
PDF下载
全屏
67
12
关闭全屏
北京市海淀区学院南路86号
010-62662699（运营及技术支持）
qkjq@cast.org.cn
