Article(id=1317125541858234933, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125500041015883, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.02.009, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791956800188, onlineDateStr=2026-10-14, pubDate=1770652800000, pubDateStr=2026-02-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791956800188, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791956800188, creator=13701087609, updateTime=1791956800188, updator=13701087609, issue=Issue{id=1317125500041015883, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='2', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1770652800000', pubDateStr='2026-02-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791956790217, creator='13701087609', updateTime=1791958795145, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133909368877755, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125500041015883, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133909373072060, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125500041015883, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=46, endPage=57, ext={EN=ArticleExt(id=1317125542172807734, articleId=1317125541858234933, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress of Chemical Composition and Pharmacological Effects of Daqingye（Isatidis Folium）and Its Quality Marker Prediction Analysis, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Daqingye（Isatidis Folium）is the dried leaves of Songlan（Isatis indigotica Fort）. Its chemical composition mainly includes alkaloids，organic acids，flavonoids，lignans，etc.，with antiviral，anti-endotoxin，anti-inflammatory，antibacterial，antioxidant，anti-tumor，immune regulation and other effects. Based on the research progress of chemical components and pharmacological effects of Daqingye（Isatidis Folium），the quality markers of Daqingye（Isatidis Folium）were predicted and analyzed from the aspects of transmission and traceability，plant genetics，chemical component specificity，effectiveness and measurability. It is predicted that indirubin，indigo，tryptanthrin，4（3H）- quinazolinone，1，2，2＇-tri-O-E-sinapoyl-β-gentiobiose，1，2，6＇-tri-O-E-sinapoylgentiobiose，isovitexin，isoscoparin and lariciresinol can be used as the candidate compounds of the quality markers of Daqingye（Isatidis Folium），which can provided a reference for improving the quality evaluation system of Daqingye（Isatidis Folium）.

, authors=Liguo YANG^{1, 2}, Xiwen SHEN^{1, 2}, Wenlong BAO^{1, 2}, authorsList=Liguo YANG, Xiwen SHEN, Wenlong BAO, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317125543942804024, articleId=1317125541858234933, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=大青叶化学成分和药理作用研究进展及其质量标志物预测分析, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

大青叶为十字花科植物菘蓝Isatis indigotica Fort.的干燥叶，其化学成分主要包括生物碱、有机酸、黄酮、木脂素等，具有抗病毒、抗内毒素、抗炎、抗菌、抗氧化、抗肿瘤、免疫调节等作用。基于大青叶化学成分和药理作用的研究进展，从质量传递与溯源、植物亲缘学与成分特有性、成分有效性、成分可测性等方面对大青叶的质量标志物进行了预测分析，初步预测靛玉红、靛蓝、色胺酮、4（3H）-喹唑酮、1，2，2＇-tri-O-E-sinapoyl-β-gentiobiose、1，2，6＇-tri-O-E-sinapoylgentiobiose、异牡荆素、异金雀花素、落叶松脂素等成分可作为大青叶质量标志物的候选化合物，为完善大青叶质量评价体系提供了参考。

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