Article(id=1317125460333548496, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.03.031, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791956780750, onlineDateStr=2026-10-14, pubDate=1773072000000, pubDateStr=2026-03-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791956780750, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791956780750, creator=13701087609, updateTime=1791956780750, updator=13701087609, issue=Issue{id=1317125400581485316, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='3', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1773072000000', pubDateStr='2026-03-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791956766504, creator='13701087609', updateTime=1791958763799, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133777898418844, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133777898418845, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=169, endPage=174, ext={EN=ArticleExt(id=1317125460941722577, articleId=1317125460333548496, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress on Chemical Composition and Anti-Tumor Mechanism of Baizhu（Atractylodis Macrocephalae Rhizoma）, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

As the rhizome of the plant of Compositaceae, the traditional Chinese medicine Baizhu（Atractylodis Macrocephalae Rhizoma）has the effects of strengthening spleen and replenishing Qi, eliminating dampness and diuresis, anti-perspirant and miscarriage prevention. Its chemical active components mainly include lactones, polysaccharides, volatile oils, flavonoids, glycosides, etc. Modern pharmacological research shows that Baizhu（Atractylodis Macrocephalae Rhizoma）has the effects of regulating gastrointestinal tract, protecting cardiovascular and nervous system, protecting liver, anti-tumor, anti-inflammatory, anti-bacterial, anti-oxidant and regulating immunity and can be used for the treatment and prevention of gastrointestinal tract, nervous system, liver, tumor and other diseases. In this review, the anti-tumor mechanism of the main chemical components of Baizhu（Atractylodis Macrocephalae Rhizoma）was summarized. It can exert anti-tumor effects by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, inhibiting tumor cell migration and invasion, blocking tumor cell cycle, inhibiting tumor neovascularization and regulating tumor microenvironment. The aim of this review was to provide important reference basis for the anti-tumor application of Baizhu（Atractylodis Macrocephalae Rhizoma）and its main chemical components.

, authors=Yumei ZHANG¹, Jingyi WANG¹, Siyuan CUI¹, Kui LIU¹, Wei ZHENG¹, Zhenzhen WANG¹, Jiyuan DING², authorsList=Yumei ZHANG, Jingyi WANG, Siyuan CUI, Kui LIU, Wei ZHENG, Zhenzhen WANG, Jiyuan DING, authorCompany=null, correspAuthors=Jingyi WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317125461184992210, articleId=1317125460333548496, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=白术有效成分及抗肿瘤机制研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

中药白术为菊科植物白术Atractylodes macrocephala Rhizoma的根茎，具有健脾益气、燥湿利水、止汗、安胎之效，其有效成分主要包括内酯类、多糖类、挥发油类、黄酮类、苷类等。现代药理学研究显示，白术具有调节胃肠道、保护心血管和神经系统、保肝、抗肿瘤、抗炎、抗菌、抗氧化、调节免疫等功效，可用于胃肠道、神经系统、肝脏、免疫系统、肿瘤等多种疾病的治疗与预防。将白术有效成分的抗肿瘤机制研究进行归纳，其可通过抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡、抑制肿瘤细胞迁移和侵袭、阻滞肿瘤细胞周期、抑制肿瘤新生血管生成和调节肿瘤微环境等多种途径发挥抗肿瘤作用。旨在为白术及其有效成分的抗肿瘤应用提供重要参考依据。

, authors=张玉梅¹, 王敬毅¹, 崔思远¹, 刘奎¹, 郑伟¹, 王振振¹, 丁继元², authorsList=张玉梅, 王敬毅, 崔思远, 刘奎, 郑伟, 王振振, 丁继元, authorCompany=null, correspAuthors=王敬毅, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=ZnI7JSNv5jqErof5QkQ5mQ==, magXml=1w9F8FPLieU/+ws1NuscGw==, pdfUrl=null, pdf=fvYr/WzB5xOPIbycU/1FIA==, pdfFileSize=1745374, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=RfjEVsrReMqYJqXk6ml6Zg==, mapNumber=null, fund=null)}, authors=[Author(id=1319724709365793464, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317125460333548496, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319724711072875196, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317125460333548496, authorId=1319724709365793464, language=EN, stringName=Yumei ZHANG, firstName=Yumei, middleName=null, lastName=ZHANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, Shandong, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319724711160955581, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317125460333548496, authorId=1319724709365793464, language=CN, stringName=张玉梅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山东中医药大学附属医院，山东 济南 250000, bio={"content":"

张玉梅（1987 -），女，山东济南人，主管技师，博士，研究方向：肿瘤诊疗临床与基础。

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张玉梅（1987 -），女，山东济南人，主管技师，博士，研究方向：肿瘤诊疗临床与基础。

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