Article(id=1317125445829636256, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.03.027, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791956777293, onlineDateStr=2026-10-14, pubDate=1773072000000, pubDateStr=2026-03-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791956777293, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791956777293, creator=13701087609, updateTime=1791956777293, updator=13701087609, issue=Issue{id=1317125400581485316, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='3', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1773072000000', pubDateStr='2026-03-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791956766504, creator='13701087609', updateTime=1791958763799, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133777898418844, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133777898418845, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=150, endPage=153, ext={EN=ArticleExt(id=1317125446022574241, articleId=1317125445829636256, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Dingchuan Decoction（定喘汤）on Children with Cough Variant Asthma（Wind-Heat Attacking Lung Syndrome）in Children with TCM Syndrome Scores, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective To study the effect of Dingchuan Decoction（定喘汤）on TCM syndrome score and airway function in children with cough variant asthma（wind-heat attacking lung syndrome）.
Methods A total of 120 children with cough variant asthma（wind-heat attacking lung syndrome）treated in the hospital from October 2023 to February 2024 were selected and divided into two groups according to the random number table method, with 60 cases in each group. The control group was treated with montelukast sodium, and the observation group was treated with Dingchuan Decoction on the basis of the control group. The course of treatment in both groups was 2 months. The efficacy, TCM syndrome scores, airway function parameters, inflammatory factors and adverse reactions were compared between the two groups.
Results The total effective rate of the observation group was 98.33%, which was significantly higher than 86.67% of the control group（P < 0.05）. After treatment, the scores of main TCM syndromes of asthma, cough and expectoration, chest tightness and irritability, red tongue and yellow moss in the two groups were significantly decreased, and the above scores in the observation group were significantly lower than those in the control group［（1.84 ± 0.33）points, （2.01 ± 0.75）points, （1.62 ± 0.28）points, （1.83 ± 0.26）points vs（2.40 ± 0.56）points, （2.42 ± 0.68）points, （2.05 ± 0.31）points, （2.04 ± 0.39）points］（P < 0.05）. After treatment. The percentage of forced expiratory volume in one second（FEV1%）, forced expiratory flow at 50% of FVC exhaled（FEF50）and forced expiratory flow at 50% of FVC exhaled（FEF75）were significantly increased. The above indexes in the observation group were significantly higher than those in the control group［（85.24 ± 7.91）%, （1.86 ± 0.46）L/s, （0.91 ± 0.20）L/s vs（82.30 ± 6.55）%, （1.69 ± 0.37）L/s, （0.82 ± 0.15）L/s］（P < 0.05）. After treatment, the levels of hypersensitive C-reactive protein（hs-CRP）, interleukin（IL）- 17 and IL-23 in the two groups were significantly decreased. The above indexes in the observation group were significantly lower than those in the control group［（7.08 ± 1.12）mg/L, （67.38 ± 7.89）ng/L, （21.36 ± 2.70）ng/L vs（10.31 ± 1.67）mg/L, （71.41 ± 6.59）ng/L, （26.08 ± 2.59）ng/L］（P < 0.05）. No serious adverse reactions occurred in both groups.
Conclusion Dingchuan Decoction has a significant effect on children with cough variant asthma（wind-heat attacking lung syndrome）. It can more effectively alleviate various TCM syndromes, reduce the airway inflammation and improve the airway function. It is safe and worthy of application.
, authors=Yun CHEN
1, Guopeng GAO
2, Lizhi QIU
3, Jin WANG
1, authorsList=Yun CHEN, Guopeng GAO, Lizhi QIU, Jin WANG, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317125446265843874, articleId=1317125445829636256, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=定喘汤对小儿咳嗽变异性哮喘（风热袭肺证）中医证候积分、气道功能的影响, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的 研究定喘汤对小儿咳嗽变异性哮喘（风热袭肺证）患儿中医证候积分、气道功能的影响。
方法 选取2023年10月—2024年2月医院治疗的小儿咳嗽变异性哮喘（风热袭肺证）患儿120例，根据随机数表法均分为两组，每组60例，对照组患儿采用孟鲁司特钠治疗，观察组患儿在对照组基础上增加定喘汤治疗，两组疗程均为2个月。比较两组患儿的疗效，中医证候积分、气道功能参数、炎症因子、不良反应发生情况。
结果 观察组总有效率98.33%，显著高于对照组的86.67%（P < 0.05）。治疗后，两组主要中医证候喘促气粗、咳嗽咯痰、胸闷烦躁、舌红苔黄积分均显著降低，并且观察组以上各项积分均显著低于对照组［（1.84 ± 0.33）分、（2.01 ± 0.75）分、（1.62 ± 0.28）分、（1.83 ± 0.26）分vs（2.40 ± 0.56）分、（2.42 ± 0.68）分、（2.05 ± 0.31）分、（2.04 ± 0.39）分］（P < 0.05）。治疗后，第一秒用力呼气量占预计值百分比（percentage of forced expiratory volume in one second，FEV1%）、用力呼出50%肺活量呼气流量（forced expiratory flow at 50% of FVC ex haled，FEF50）、用力呼出75%肺活量呼气流量（forced expiratory flow at 50% of FVC ex haled，FEF75）均显著升高，并且观察组以上各项指标显著高于对照组［（85.24 ± 7.91）%、（1.86 ± 0.46）L/s、（0.91 ± 0.20）L/s vs（82.30 ± 6.55）%、（1.69 ± 0.37）L/s、（0.82 ± 0.15）L/s］（P < 0.05）。治疗后，两组超敏C反应蛋白（hypersensitive C-reactive protein，hs-CRP）、白细胞介素（interleukin，IL）-17、IL-23均显著降低，并且观察组以上各项指标显著低于对照组［（7.08 ± 1.12）mg/L、（67.38 ± 7.89）ng/L、（21.36 ± 2.70）ng/L vs（10.31 ± 1.67）mg/L、（71.41 ± 6.59）ng/L、（26.08 ± 2.59）ng/L］（P < 0.05）。两组均无严重不良反应发生。
结论 定喘汤对小儿咳嗽变异性哮喘（风热袭肺证）患儿疗效显著，能够更有效地缓解各种中医证候，并降低气道炎症反应、改善气道功能，安全性良好，值得应用。
, authors=陈允
1, 高国鹏
2, 邱立志
3, 王锦
1, authorsList=陈允, 高国鹏, 邱立志, 王锦, authorCompany=null, correspAuthors=null, authorNote=
陈允（1988 -），女，河南南阳人，主治医师，硕士，研究方向；小儿呼吸、消化系统疾病。
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