Article(id=1317125437436842796, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.03.025, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791956775291, onlineDateStr=2026-10-14, pubDate=1773072000000, pubDateStr=2026-03-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791956775291, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791956775291, creator=13701087609, updateTime=1791956775291, updator=13701087609, issue=Issue{id=1317125400581485316, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='3', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1773072000000', pubDateStr='2026-03-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791956766504, creator='13701087609', updateTime=1791958763799, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133777898418844, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133777898418845, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317125400581485316, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=134, endPage=143, ext={EN=ArticleExt(id=1317125437675918125, articleId=1317125437436842796, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress on Signaling Pathways Related to Prevention and Treatment of Cervical Cancer with Traditional Chinese Medicine, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

As one of the most common malignant tumors in the female reproductive system worldwide, cervical cancer poses a huge threat to women＇s health. The occurrence of cervical cancer is related to a variety of factors, including viral infection, unclean sexual life, poor hygiene habits, etc., among which persistent infection with high-risk human papilloma virus（HPV）is the primary risk factor for its pathogenesis. Traditional Chinese medicine（TCM）is playing an increasingly important role in the prevention and treatment of cervical cancer. Traditionally, TCM has been used to treat diseases by adjusting the overall balance of the human body and enhancing the body＇s resistance. Modern medical research has also shown that TCM can not only promote the apoptosis of cervical cancer cells, but also regulate the immune function of the patients and reduce the complications of Western medicine treatment. For example, TCM monomers are effective against cervical cancer by inhibiting the PI3K/AKT/mTOR signaling pathway. In addition, TCM has also shown unique advantages in postoperative rehabilitation of cervical cancer and improvement of quality of life, such as the research progress of TCM in the prevention and treatment of postoperative urinary retention and lymphedema of the lower limbs of cervical cancer. The purpose of this review was to systematically summarize the research progress of TCM in the prevention and treatment of cervical cancer, explore the impact of TCM on cervical cancer-related signaling pathways, and how to better apply TCM in clinical practice. The significance of the research was to provide more treatment options for cervical cancer patients, improve the treatment effect and the quality of life of the patients, and also provide direction for the future research. Through in-depth research on the mechanism of action of TCM, it can better understand the role of TCM in the prevention and treatment of cervical cancer, and provide more scientific basis for clinical practice.

, authors=Yuwei MA¹, Ying CAO², Wenping WANG³, authorsList=Yuwei MA, Ying CAO, Wenping WANG, authorCompany=null, correspAuthors=Wenping WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317125437931770670, articleId=1317125437436842796, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=中医药防治宫颈癌相关信号通路的研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

宫颈癌作为全球女性生殖系统中最常见的恶性肿瘤之一，对女性健康构成了巨大的威胁。宫颈癌的发生与多种因素有关，包括病毒感染、不洁性生活、不良卫生习惯等，其中高危型人乳头状瘤病毒（human papilloma virus，HPV）的持续感染是其发病的首要危险因素。中医药在宫颈癌的防治中扮演着越来越重要的角色。传统上，中医药通过调整人体的整体平衡，增强机体的抵抗力，从而达到治疗疾病的目的。现代医学研究也表明，中药不仅能促进宫颈癌细胞的凋亡，还能调节患者的免疫功能，减少西医治疗的并发症。例如，中药单体通过抑制磷脂酰肌醇-3激酶/蛋白激酶B/哺乳动物雷帕霉素靶蛋白（phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin，PI3K/AKT/mTOR）信号通路对宫颈癌有效。此外，中医药在宫颈癌术后康复和提高生活质量方面也显示出独特的优势，如中医药在防治宫颈癌术后尿潴留、下肢淋巴水肿等方面的研究进展。综述的目的在于系统总结中医药在宫颈癌防治中的研究进展，探讨中医药对宫颈癌相关信号通路的影响，以及如何在临床实践中更好地应用中医药。研究的意义在于为宫颈癌患者提供更多的治疗选择，改善治疗效果，提高患者生活质量，同时也为未来的研究提供方向。通过深入研究中医药的作用机制，可以更好地理解中医药在宫颈癌防治中的作用，为临床提供更多的科学依据。

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马雨薇（1996 -），女，辽宁沈阳人，博士在读，研究方向：中西医结合防治恶性肿瘤。

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马雨薇（1996 -），女，辽宁沈阳人，博士在读，研究方向：中西医结合防治恶性肿瘤。

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