Article(id=1317115255596109873, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.05.036, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954347752, onlineDateStr=2026-10-14, pubDate=1778342400000, pubDateStr=2026-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954347752, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954347752, creator=13701087609, updateTime=1791954347752, updator=13701087609, issue=Issue{id=1317115025307845060, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1778342400000', pubDateStr='2026-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954292847, creator='13701087609', updateTime=1791958713604, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133567340171275, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133567340171276, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=193, endPage=203, ext={EN=ArticleExt(id=1317115255793242162, articleId=1317115255596109873, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress of Chemical Composition, Pharmacological Effects and Clinical Application of Dayuan Decoction (达原饮) and Prediction of Its Quality Markers, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Dayuan Decoction (达原饮), a classic prescription, comes from The Theory ofEpidemic Fever written by WU Youke, a famous doctor in the Ming Dynasty. It is a representative prescription for treating epidemic diseases, which has the effects of opening onto the pleurodiaphragmatic interspace and repelling filth and transforming turbidity. It is widely used in modern clinic to treat viral infectious diseases, acute liver and lung injury, fever, insomnia and pediatric diseases. The chemical composition, pharmacological action and clinical application of Dayuan Decoction in recent years were summarized and the quality marker (Q-Marker) of this formula was predicted and analyzed according to the concept of Q-Marker. The results showed that arecoline, quercetin, magnolol, honokiol, epicatechin, protocatechuic acid, mangiferin, timosaponin AⅢ, paeoniflorin, albiflorin, benzoylpaeoniflorin, baicalin, baicalein, liquiritin, glycyrrhizicacid, glycyrrhetinic acid and isoliquiritigenin can be used as the Q-Markers, which could provide a reference for the quality control system and the development of Dayuan Decoction.

, authors=Jing ZHANG^{1, 2}, Jianping ZHANG², Dongying ZHAO², Nengting HUANG^{2, 3}, Yanying LI³, Xinyu ZANG^{2, 3}, Jing HU^{1, 2, 3}, authorsList=Jing ZHANG, Jianping ZHANG, Dongying ZHAO, Nengting HUANG, Yanying LI, Xinyu ZANG, Jing HU, authorCompany=null, correspAuthors=Xinyu ZANG, Jing HU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115256170729523, articleId=1317115255596109873, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=经典名方达原饮化学成分、药理作用、临床应用的研究进展及其质量标志物预测分析, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

经典名方达原饮出自明代著名医家吴又可所著的《温疫论》，是治疗疫病的代表方剂，具有开达膜原、辟秽化浊的功效，现代临床多用于治疗病毒传染性疾病、急性肝肺损伤、发热、失眠及儿科疾病等，应用广泛。在对近年来达原饮的化学成分、药理作用及临床应用进行归纳总结的基础上，依照质量标志物（quality marker，Q-Marker）“五原则”进行预测分析，结果提示槟榔碱、槲皮素、厚朴酚、和厚朴酚、表儿茶素、原儿茶酸、芒果苷、知母皂苷AIII、芍药苷、芍药内酯苷、苯甲酰芍药苷、黄芩苷、黄芩素、甘草苷、甘草酸、甘草次酸、异甘草素可作为达原饮的质量标志物，为其质量控制体系的建立及后续制剂的开发提供参考。

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张静（2001-），女，甘肃天水人，硕士在读，研究方向：中药学。

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张静（2001-），女，甘肃天水人，硕士在读，研究方向：中药学。

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