中华中医药学刊

类器官技术在中医药领域应用前景的系统回顾与展望

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陈浩 ¹^,² , 刘玉红 ¹ , 钟凌云 ¹ , 卢兴美 ¹ , 王万春 ² , 孙伟 ¹ , 刘绍姜 ¹ , 李蕊 ¹ , 周丽 ³ , 翁剑锋 ²

中华中医药学刊 | 国家项目点击 2026,44(5): 44-48

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中华中医药学刊 |国家项目点击 2026 , 44 (5) : 44 -48

类器官技术在中医药领域应用前景的系统回顾与展望

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陈浩¹^,², 刘玉红¹, 钟凌云¹, 卢兴美¹, 王万春², 孙伟¹, 刘绍姜¹, 李蕊¹, 周丽³, 翁剑锋²

作者信息

^1．江西中医药大学药学院，江西南昌 330004

^2．江西中医药大学附属医院，江西南昌 330006

^3．江西中医药大学计算机学院，江西南昌 330004

通讯作者:

翁剑锋（1978-），男，江西南昌人，副主任药师，学士，研究方向：医院药学。E-mail：8872254@qq.com。

作者简介:

陈浩（1982-），男，江西南昌人，副教授、副主任药师，硕士研究生导师，博士，研究方向：中医药方证结合及中药炮制学。

System Reviews and Outlook for Organoid Technology in the Field of Traditional Chinese Medicine

Hao CHEN¹^,², Yuhong LIU¹, Lingyun ZHONG¹, Xingmei LU¹, Wanchun WANG², Wei SUN¹, Shaojiang LIU¹, Rui LI¹, Li ZHOU³, Jianfeng WENG²

Affiliations

^1. School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, Jiangxi, China

^2. The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang 330006, Jiangxi, China

^3. School of Computer, Jiangxi University of Chinese Medicine, Nanchang 330004, Jiangxi, China

出版时间: 2026-05-10 doi: 10.13193/j.issn.1673-7717.2026.05.008

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摘要

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人类3D类器官技术作为一项重大的技术突破，通过揭示组织或器官的生长状态、结构、功能和特征弥合了发育生物学和精准医学方面长期存在的差距，在重建能够真正模拟人体肝脏的体外实验模型中发挥着重要作用。当前，类器官技术正处于快速发展的时期，其组织、器官的结构与功能仿真程度也在逐步提升，随着类器官系统概括体内器官结构和人造组织器官的水平越来越高，其应用领域也越来越广泛。其中类器官系统和芯片技术的结合开辟了类器官工程的新领域，有望解决现有类器官系统面临的挑战，并扩大其生物医学的应用领域。同时在中医药的质量控制、药效学评价、复方配伍等应用方面，类器官技术也将发挥出极其重要的作用。

关键词

类器官技术 / 中医药应用 / 芯片技术

Abstract

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As a major technological breakthrough, human 3D organoid technology, through revealing the growth status, structure, function and characteristics of tissue or organs, bridges the long-standing gap between developmental biology and precision medicine. It plays an important role in reconstructing in vitro experimental models capable of truly simulating the human liver. At present, organoid technology is in a period of rapid development, and its structure and functional simulation of their organizations and organs are gradually increasing. With the increasing level of summarizing the internal organ structure and artificial tissue organs in organoid systems, its application fields are also becoming more and more extensive. The combination of organoid systems and chip technology has opened up a new field of organoid engineering, which is expected to solve the challenges faced by existing organoid systems and expand their biomedical applications. At the same time, in terms of the quality control, efficacy evaluation and composite compatibility in traditional Chinese medicine, the technology will also play an extremely important role.

Key words

organoid technology / traditional Chinese medicine application / chip technology

引用本文

陈浩, 刘玉红, 钟凌云, 卢兴美, 王万春, 孙伟, 刘绍姜, 李蕊, 周丽, 翁剑锋. 类器官技术在中医药领域应用前景的系统回顾与展望. 中华中医药学刊, 2026 , 44 (5) : 44 -48 . DOI: 10.13193/j.issn.1673-7717.2026.05.008

Hao CHEN, Yuhong LIU, Lingyun ZHONG, Xingmei LU, Wanchun WANG, Wei SUN, Shaojiang LIU, Rui LI, Li ZHOU, Jianfeng WENG. System Reviews and Outlook for Organoid Technology in the Field of Traditional Chinese Medicine[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (5) : 44 -48 . DOI: 10.13193/j.issn.1673-7717.2026.05.008

基金

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国家自然科学基金项目(82360966)
国家中医药管理局全国老药工传承工作室项目(2023QGZDSYS001)
江西省中医药科技计划重点项目(2023Z009)
江西省教育厅科学技术研究项目(GJJ2200959)

参考文献

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参考文献引证文献

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2026年第44卷第5期

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文章信息

doi: 10.13193/j.issn.1673-7717.2026.05.008

首发时间：2026-10-14
出版时间：2026-05-10

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出版历史

基金

国家自然科学基金项目(82360966)

国家中医药管理局全国老药工传承工作室项目(2023QGZDSYS001)

江西省中医药科技计划重点项目(2023Z009)

江西省教育厅科学技术研究项目(GJJ2200959)

作者信息

^1．江西中医药大学药学院，江西南昌 330004

^2．江西中医药大学附属医院，江西南昌 330006

^3．江西中医药大学计算机学院，江西南昌 330004

通讯作者:

翁剑锋（1978-），男，江西南昌人，副主任药师，学士，研究方向：医院药学。E-mail：8872254@qq.com。

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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