Article(id=1317115040096964908, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.06.011, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954296372, onlineDateStr=2026-10-14, pubDate=1781020800000, pubDateStr=2026-06-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954296372, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954296372, creator=13701087609, updateTime=1791954296372, updator=13701087609, issue=Issue{id=1317114999827452826, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='6', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1781020800000', pubDateStr='2026-06-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954286772, creator='13701087609', updateTime=1791958677365, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133415753831385, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133415753831386, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=66, endPage=73, ext={EN=ArticleExt(id=1317115040407343405, articleId=1317115040096964908, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Study of Chemical Composition, Pharmacological Effects and Prediction of Quality Markers (Q-Marker) of Yinchen Wuling Powder (茵陈五苓散), columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Yinchen Wuling Powder (茵陈五苓散, YWP) has the efficacy of clearing heat, detoxicating and inducing dampness, strengthening spleen and stomach, and resolving turbidity. Modern studies have shown that this formula has the hepatoprotective, choleretic, cardiovascular protection and anti-inflammatory effects. It is commonly used in the treatment of jaundice, metabolic diseases and cardiovascular diseases in clinical practice. In this paper, it systematically summarized and sorted out the chemical composition and pharmacological effects of YWP, and carried out the prediction analysis of its quality markers (Q-Markers) according to the concept of Q-Markers based on the five principles, and the results showed that chlorogenic acid, artemisinin lactone, chromogenic ketone, swertiamarin bitter glycoside, 3, 5-O-dicaffeoylquinic acid, 4, 5-O-di caffeoylquinic acid, atractylenolide Ⅰ, atractylenolide Ⅱ, atractylenolide Ⅲ, atractylenolide, craniospermone, cinnamic acid, cinnamaldehyde, porinic acid, tuliptic acid, dehydrotuliptic acid, 2, 3-acetylzelenol B, 2, 3-acetylzelenol C, zeylenol B and ergosterol could be used as the Q-Markers of YWP, which would be used as a reference for the subsequent studies of the quality control of YWP and its related formulations.

, authors=Linjing SHE, Yilong HU, Meng'en YANG, Zhengwang ZHU, Mingsan MIAO, Pingsheng ZHU, authorsList=Linjing SHE, Yilong HU, Meng'en YANG, Zhengwang ZHU, Mingsan MIAO, Pingsheng ZHU, authorCompany=null, correspAuthors=Pingsheng ZHU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115040944214318, articleId=1317115040096964908, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=茵陈五苓散化学成分、药理作用研究及质量标志物（Q-Marker）预测, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

茵陈五苓散具有清热解毒利湿、健脾和胃化浊的功效。现代研究表明该方具有保肝利胆、保护心血管、抗炎等作用，临床上常用于治疗黄疸、代谢疾病、心血管疾病等。通过对茵陈五苓散的化学成分、药理作用进行系统总结与梳理，依照质量标志物（quality marker，Q-Marker）理念，根据五原则对其Q-Marker进行预测分析，结果显示绿原酸、滨蒿内酯、色原酮、獐芽菜苦苷、3，5-O-二咖啡酰奎宁酸、4，5-O-二咖啡酰奎宁酸、白术内酯Ⅰ、白术内酯Ⅱ、白术内酯Ⅲ、苍术酮、肉桂酸、桂皮醛、茯苓酸、土莫酸、去氢土莫酸、2，3-乙酰泽泻醇B、2，3-乙酰泽泻醇C、泽泻醇B、麦角甾醇可作为茵陈五苓散的Q-Marker，为茵陈五苓散及其相关制剂的质量控制等后续研究提供参考。

, authors=佘琳静, 胡毅龙, 杨蒙恩, 朱正望, 苗明三, 朱平生, authorsList=佘琳静, 胡毅龙, 杨蒙恩, 朱正望, 苗明三, 朱平生, authorCompany=null, correspAuthors=朱平生, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=1l7iiGkAKtfz/v3S121VWw==, magXml=tJTwEhmZGtFxwqdAbTNigA==, pdfUrl=null, pdf=KdghHUpTmcttL7XPC0wENw==, pdfFileSize=2743895, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=ms1BGVEEUrXkbhwsu8jmWg==, mapNumber=null, fund=null)}, authors=[Author(id=1319631183776956732, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115040096964908, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319631183852454206, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115040096964908, authorId=1319631183776956732, language=EN, stringName=Linjing SHE, firstName=Linjing, middleName=null, lastName=SHE, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Henan University of Chinese Medicine, Zhengzhou 450000, Henna, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319631183919563071, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115040096964908, authorId=1319631183776956732, language=CN, stringName=佘琳静, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=河南中医药大学，河南 郑州 450000, bio={"content":"

佘琳静（1997-），女，河南长垣人，博士在读，研究方向：中医药防治肝胆疾病。

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佘琳静（1997-），女，河南长垣人，博士在读，研究方向：中医药防治肝胆疾病。

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