Article(id=1319291305696539295, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.09.043, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473158524, onlineDateStr=2026-10-20, pubDate=1788969600000, pubDateStr=2026-09-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473158524, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473158524, creator=13701087609, updateTime=1792473158524, updator=13701087609, issue=Issue{id=1319291166823142311, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='9', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1788969600000', pubDateStr='2026-09-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792473125414, creator='13701087609', updateTime=1792473357559, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292140618896016, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292140618896017, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=232, endPage=235, ext={EN=ArticleExt(id=1319291307432981152, articleId=1319291305696539295, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Clinical Effect and Safety Observation of Modified Qianjin Weijian Decoction (千金苇茎汤加减) Combined with Azithromycin in Treatment of Mycoplasma Pneumonia in Children with Phlegm-Heat Blocking Lung Syndrome, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the clinical effect and safety of Modified Qianjin Weijian Decoction (千金苇茎汤加减) combined with azithromycin in the treatment of mycoplasma pneumonia in children with phlegm-heat blocking lung syndrome.
Methods A total of 58 children with mycoplasma pneumonia with phlegm-heat blocking lung syndrome (admitted from August 2021 to February 2024) were included in the study. All the children received conventional treatment, and were divided into azithromycin single-drug group (29 cases) and azithromycin combined Chinese medicine group (29 cases) by random number table method. The therapeutic effect, adverse reactions, time for symptoms and signs to disappear, TCM syndrome scores before and after treatment and serum levels of procalcitonin (PCT), interleukin-6 (IL-6), C-reactive protein, forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC and other lung function indicators, and T lymphocyte subsets were compared between the two groups.
Results The total effective rate of the azithromycin combined Chinese medicine group was higher than that of azithromycin single-drug group (P<0.05). The adverse reaction rate of azithromycin singledrug group and azithromycin combined Chinese medicine group was lower (P>0.05). The disappearance time of symptoms and signs in the azithromycin combined Chinese medicine group was shorter than that in the single medicine group (P<0.05). The levels of TCM syndrome scores, inflammatory factors (PCT, IL-6, CRP), lung function indexes (FVC, FEV1, FEV1/FVC) and T lymphocyte subsets were compared between the two groups before treatment (P>0.05). After treatment, TCM syndrome scores, inflammatory factors (PCT, IL-6, CRP), lung function indexes (FVC, FEV1, FEV1/FVC) and T lymphocyte subsets of children in both groups were improved. The levels of TCM syndrome scores, inflammatory factors (PCT, IL-6, CRP), lung function indexes (FVC, FEV1, FEV1/FVC) and T lymphocyte subsets in the azithromycin combined Chinese medicine group after treatment were better than those in the monotherapy group (P<0.05).
Conclusion Modified Qianjin Weijian Decoction combined with azithromycin has good clinical effect on mycoplasma pneumonia in children with phlegm-heat blocking lung syndrome, and is safe and reliable.
, authors=Erzhao PANG, Leifeng HE, Yudan ZHANG, Jing JIANG, authorsList=Erzhao PANG, Leifeng HE, Yudan ZHANG, Jing JIANG, authorCompany=null, correspAuthors=Leifeng HE, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291307885965985, articleId=1319291305696539295, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=千金苇茎汤加减汤联合阿奇霉素治疗痰热闭肺证儿童支原体肺炎临床效果与安全性观察, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探讨千金苇茎汤加减汤联合阿奇霉素治疗痰热闭肺证儿童支原体肺炎临床效果与安全性。
方法 纳入58例痰热闭肺证儿童支原体肺炎（2021年8月—2024年2月收治）进行研究，患儿均接受常规治疗，采取随机数字表法将患儿分为采取阿奇霉素治疗的单药组（29例）以及采取千金苇茎汤加减汤联合阿奇霉素治疗的联合中药组（29例），比较两组儿童治疗效果、不良反应、症状及体征消失时间、治疗前后中医证候积分与血清降钙素原（Procalcitonin，PCT）、白细胞介素-6（Interleukin-6，IL-6）及C-反应蛋白（C-reactive protein，CRP）水平变化、用力肺活量（Forced Vital Capacity，FVC）、一秒用力呼气容积（Forced Expiratory Volume in the first second，FEV1）及FEV1/FVC等肺功能指标变化、T淋巴细胞亚群水平变化。
结果 联合中药组患者治疗总有效率高于单药组，P<0.05；单药组、联合中药组不良反应率均较低，P>0.05；联合中药组患者症状及体征消失时间均比单药组更短，P<0.05；治疗前两组儿童中医证候积分、炎症因子（PCT、IL-6、CRP）、肺功能指标（FVC、FEV1、FEV1/FVC）、T淋巴细胞亚群水平比较，P>0.05，治疗后两组儿童中医症候积分、炎症因子（PCT、IL-6、CRP）、肺功能指标（FVC、FEV1、FEV1/FVC）、T淋巴细胞亚群水平均改善，联合中药组儿童治疗后中医证候积分、炎症因子（PCT、IL-6、CRP）、肺功能指标（FVC、FEV1、FEV1/FVC）、T淋巴细胞亚群水平均优于单药组儿童，P<0.05。
结论 千金苇茎汤加减汤联合阿奇霉素治疗痰热闭肺证儿童支原体肺炎临床效果佳，安全可靠。
, authors=庞二召, 何雷锋, 张玉丹, 江静, authorsList=庞二召, 何雷锋, 张玉丹, 江静, authorCompany=null, correspAuthors=何雷锋, authorNote=
庞二召（1982-），男，河南平顶山人，副主任医师，硕士，研究方向：中医药防治儿童呼吸系统疾病。
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何雷锋（1983-），男，河南洛阳人，副主任中医师，硕士，研究方向：儿科呼吸系统疾病。
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庞二召（1982-），男，河南平顶山人，副主任医师，硕士，研究方向：中医药防治儿童呼吸系统疾病。
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庞二召（1982-），男，河南平顶山人，副主任医师，硕士，研究方向：中医药防治儿童呼吸系统疾病。
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