Article(id=1319291338886070666, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.09.017, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473166437, onlineDateStr=2026-10-20, pubDate=1788969600000, pubDateStr=2026-09-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473166437, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473166437, creator=13701087609, updateTime=1792473166437, updator=13701087609, issue=Issue{id=1319291166823142311, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='9', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1788969600000', pubDateStr='2026-09-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1792473125414, creator='13701087609', updateTime=1792473357559, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292140618896016, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292140618896017, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291166823142311, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=97, endPage=104, ext={EN=ArticleExt(id=1319291339083202955, articleId=1319291338886070666, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Study on Mechanism of Chuanxiong (Chuanxiong Rhizoma) on Nervous System Diseases, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

As a traditional medicinal material in China, Chuanxiong (Chuanxiong Rhizoma) has a long history of medicinal use. It can promote blood circulation, promote Qi, dispel wind, relieve pain, etc. It is a traditional Chinese medicine of promoting blood circulation and removing blood stasis. The pathogenesis of neurological diseases is complex and the symptoms are lingering, which seriously affects the health and quality of life of the patients. Modern pharmacological research has found that Chuanxiong (Chuanxiong Rhizoma) and its active ingredients, volatile oil and alkaloids, have the pharmacological effects of enhancing vascular endothelial function, improving coronary blood flow, lowering blood pressures, antioxidant free radicals, anti-inflammation, anti-platelet aggregation, anti-thrombosis, anti-cerebral ischemia, protecting nerve and other aspects. The inhibition of neuronal apoptosis, antioxidant, inhibition of nerve cell inflammation, protection of neurons and other effects have a good prevention and treatment effect on central nervous system diseases. This paper summarized the researches on the treatment of migraine, ischemic stroke, Alzheimer's disease and epilepsy in order to provide a scientific basis for the clinical application and basic research of Chuanxiong (Chuanxiong Rhizoma) in nervous system diseases.

, authors=Shaobo YAN¹, Xia LIU¹, Yongli WANG¹, Yan DU¹, Ye LU², Lin PEI², authorsList=Shaobo YAN, Xia LIU, Yongli WANG, Yan DU, Ye LU, Lin PEI, authorCompany=null, correspAuthors=Lin PEI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291339448107404, articleId=1319291338886070666, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=川芎对神经系统疾病的作用机制研究, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

川芎作为我国传统药材，药用历史悠久，其可活血、行气、祛风、止痛等，是中医常用的活血化瘀中药材。神经系统疾病的发病机制复杂，症状缠绵，严重影响患者的健康和生活质量。现代药理研究发现川芎及其有效成分挥发油、生物碱等具有改善血管内皮功能、降血压，抗氧自由基、抗炎，抗脑缺血、保护神经等多方面的药理作用，多靶点药理作用，其中抑制神经元凋亡、抗氧化、抑制神经细胞炎症、保护神经元等作用对中枢神经系统疾病具有良好的防治功效。通过阐述川芎对缺血性卒中（ischemic stroke，IS）、偏头痛（Migraine）、阿尔茨海默病（Alzheimer's disease，AD）、癫痫（Epilepsy）治疗的研究进行总结，以期为川芎在中枢神经系统疾病的临床应用和基础研究提供科学依据。

, authors=严少博¹, 刘霞¹, 王永利¹, 杜燕¹, 芦晔², 裴林², authorsList=严少博, 刘霞, 王永利, 杜燕, 芦晔, 裴林, authorCompany=null, correspAuthors=裴林, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=LP+sKEqCAHBA+1fZv3Afiw==, magXml=DmCVZ7uIMxaTfxOjw43uKQ==, pdfUrl=null, pdf=qHhX7Bp2oO0Z6L4tE/QEtA==, pdfFileSize=1747623, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=CQZ0738TxrhUYxZOyz1pXw==, mapNumber=null, fund=null)}, authors=[Author(id=1319291339913675156, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291338886070666, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291340001755542, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291338886070666, authorId=1319291339913675156, language=EN, stringName=Shaobo YAN, firstName=Shaobo, middleName=null, lastName=YAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.Zhangjiakou Institute of Traditional Chinese Medicine, Zhangjiakou 075000, Hebei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291340060475799, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291338886070666, authorId=1319291339913675156, language=CN, stringName=严少博, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.张家口市中医院，河北　张家口　075000, bio={"content":"

严少博（1992-），男，河北石家庄人，主治中医师，硕士，研究方向：中医药防治脑病。

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严少博（1992-），男，河北石家庄人，主治中医师，硕士，研究方向：中医药防治脑病。

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