Article(id=1319291735189078726, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.029, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473260924, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473260924, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473260924, creator=13701087609, updateTime=1792473260924, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=160, endPage=169, ext={EN=ArticleExt(id=1319291735398793927, articleId=1319291735189078726, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress on Chemical Composition, Pharmacological Action and Clinical Application of Wuwei Xiaodu Drink (五味消毒饮) and Predictive Analysis of Quality Markers, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Wuwei Xiaodu Drink (五味消毒饮) is a heat-clearing agent that has the effects of clearing heat, detoxifying and dissipating sores. It is commonly used in clinical practice to treat various diseases such as acne, acute mastitis, cellulitis, acute urinary tract infections, cholecystitis, pneumonia and so on. Based on the summary of the research progress on the chemical composition, pharmacological effects and clinical applications of Wuwei Xiaodu Drink, the quality markers (Q-Markers) of Wuwei Xiaodu Drink was predicted and analyzed according to the “five principles” of traditional Chinese medicine Q-Markers. The results showed that chlorogenic acid, esculetin, chicoric acid, caffeic acid, linarin, quercetin, 6,7-dihydroxycoumarin, kaempferide, griffonilide, lithospermoside and berberine hydrochloride were used to predict and analyze its Q-Markers, providing reference for the research on the quality control of Wuwei Xiaodu Drink and related preparations.

, authors=Na LI, Nan NAN, Yaohui XIE, Chengyi LI, Linghua ZHANG, Xiaocheng WEI, authorsList=Na LI, Nan NAN, Yaohui XIE, Chengyi LI, Linghua ZHANG, Xiaocheng WEI, authorCompany=null, correspAuthors=Chengyi LI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291737303007944, articleId=1319291735189078726, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=经典名方五味消毒饮化学成分、药理作用、临床应用研究进展及质量标志物（Q-Marker）预测分析, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

五味消毒饮为清热剂，有清热解毒、消散疔疮等功效，临床上多用于治疗痤疮、急性乳腺炎、蜂窝组织炎、急性泌尿系感染、胆囊炎、肺炎等多种疾病。在对五味消毒饮化学成分、药理作用和临床应用的研究进展进行概括归纳总结的基础上，依据中药质量标志物（quality marker，Q-Marker）“五原则”对其Q-Marker进行预测分析，结果显示绿原酸、木犀草苷、菊苣酸、咖啡酸、蒙花苷、槲皮素、秦皮乙素、山柰素、格列风内酯、紫草氰苷、小檗碱等可作为五味消毒饮的Q-Marker，为五味消毒饮及其相关制剂的质量控制等研究提供参考。

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李娜（2000-），女，甘肃陇西人，硕士在读，研究方向：中药鉴定与品质评价。

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李娜（2000-），女，甘肃陇西人，硕士在读，研究方向：中药鉴定与品质评价。

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