Article(id=1319291683414589651, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.027, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473248579, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473248579, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473248579, creator=13701087609, updateTime=1792473248579, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=148, endPage=153, ext={EN=ArticleExt(id=1319291683594944724, articleId=1319291683414589651, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Discussion on Intervention of Kaixin Powder (开心散) and Its Formula Components on Glucose and Lipid Metabolism, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Kaixin Powder (开心散) is simple in composition and has great efficacy, which is mainly used to treat emotional and cognitive disorders. Thoroughly analyzing the essence of the composition of Kaixin Powder is beneficial for the “inheritance” and “innovation” of classic traditional Chinese medicine formulas. In addition to being commonly used to treat Alzheimer's disease and depression, Kaixin Powder is also used to treat disorders of glucose and lipid metabolism, including coronary heart disease and angina pectoris. Kaixin Powder revolves around the basic pathogenesis of “spleen dampness and kidney dryness”, using a combination of sweet, bitter and spicy ingredients, which is in line with the basic theory of traditional Chinese medicine, as well as the core pathogenesis of disorders in glucose and lipid metabolism and related diseases such as “spleen dysfunction, kidney Qi deficiency, and phlegm dampness”. The research on the intervention of Kaixin Powder and its components in glucose and lipid metabolism disorders mainly focuses on intervening in the hypothalamic-pituitary-adrenal (HPA) axis, regulating gut microbiota, anti chronic inflammation and antioxidant stress. This article can provide reference and inspiration for Kaixin Powder and its components to intervene in glucose and lipid metabolism disorders and expand their clinical applications.

, authors=Zhiyan ZHONG, Xiaorui WANG, Lin LIU, Yusheng SHEN, Binbin ZHAO, Mingwang KONG, authorsList=Zhiyan ZHONG, Xiaorui WANG, Lin LIU, Yusheng SHEN, Binbin ZHAO, Mingwang KONG, authorCompany=null, correspAuthors=Mingwang KONG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291683951460565, articleId=1319291683414589651, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=开心散及其组方成分干预糖脂代谢研究, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

开心散组方药简力宏，主要用于治疗情志障碍类疾病，深入剖析开心散的组方要义有益于中医经典方剂的“继承”与“创新”。开心散除了常用于治疗阿尔茨海默病、抑郁症外，还用于治疗包括冠心病心绞痛在内的糖脂代谢紊乱疾病。开心散围绕“脾湿肾燥”的基本病机，以甘苦辛配伍，符合中医中药基础理论，也契合糖脂代谢紊乱及相关疾病“脾运失健、肾气亏虚、痰湿为患”的核心病机。开心散及其组方成分干预糖脂代谢紊乱的研究主要集中在干预下丘脑-垂体-肾上腺（hypothalamic-pituitary-adrenal，HPA）轴、调节肠道菌群、抗慢性炎症、抗氧化应激等方面。为开心散及其组方成分干预糖脂代谢紊乱并拓展其临床应用提供参考与启示。

, authors=钟志艳, 王晓瑞, 刘琳, 沈宇声, 赵宾宾, 孔明望, authorsList=钟志艳, 王晓瑞, 刘琳, 沈宇声, 赵宾宾, 孔明望, authorCompany=null, correspAuthors=孔明望, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=Bd3v678j9nboZweGIMmARQ==, magXml=SFVkNJUpF8Gl4boiwyjlEA==, pdfUrl=null, pdf=FhHAKK6rrWQA5V0OJeXKBw==, pdfFileSize=1796947, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=1ELO7pdNNq79EbV0Lgfr9w==, mapNumber=null, fund=null)}, authors=[Author(id=1319291684240867546, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291684320559324, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684240867546, language=EN, stringName=Zhiyan ZHONG, firstName=Zhiyan, middleName=null, lastName=ZHONG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291684387668189, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684240867546, language=CN, stringName=钟志艳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio={"content":"

钟志艳（1992-），女，广西玉林人，博士在读，研究方向：老年病的防治和中医基础理论。

"}, bioImg=null, bioContent=

钟志艳（1992-），女，广西玉林人，博士在读，研究方向：老年病的防治和中医基础理论。

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])]), Author(id=1319291684471554271, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291684551246049, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684471554271, language=EN, stringName=Xiaorui WANG, firstName=Xiaorui, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291684614160610, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684471554271, language=CN, stringName=王晓瑞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])]), Author(id=1319291684685463780, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291684773544166, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684685463780, language=EN, stringName=Lin LIU, firstName=Lin, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291684849041639, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684685463780, language=CN, stringName=刘琳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])]), Author(id=1319291684928733417, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291685008425195, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684928733417, language=EN, stringName=Yusheng SHEN, firstName=Yusheng, middleName=null, lastName=SHEN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291685071339756, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291684928733417, language=CN, stringName=沈宇声, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])]), Author(id=1319291685146837230, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291685230723312, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291685146837230, language=EN, stringName=Binbin ZHAO, firstName=Binbin, middleName=null, lastName=ZHAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291685293637873, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291685146837230, language=CN, stringName=赵宾宾, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])]), Author(id=1319291685356552435, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=13349959661@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1319291685427855605, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291685356552435, language=EN, stringName=Mingwang KONG, firstName=Mingwang, middleName=null, lastName=KONG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291685503353078, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, authorId=1319291685356552435, language=CN, stringName=孔明望, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=湖北中医药大学基础医学院，湖北　武汉　430065, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])])], keywords=[Keyword(id=1319291685633376503, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=EN, orderNo=1, keyword=Kaixin Powder (开心散)), Keyword(id=1319291685713068280, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=EN, orderNo=2, keyword=glucose and lipid metabolism), Keyword(id=1319291685771788537, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=EN, orderNo=3, keyword=spleen dampness and kidney dryness), Keyword(id=1319291685843091706, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=EN, orderNo=4, keyword=insulin resistance), Keyword(id=1319291687478870267, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=EN, orderNo=5, keyword=essence of formula formation), Keyword(id=1319291687550173436, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=CN, orderNo=1, keyword=开心散), Keyword(id=1319291687617282301, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=CN, orderNo=2, keyword=糖脂代谢), Keyword(id=1319291687692779774, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=CN, orderNo=3, keyword=脾湿肾燥), Keyword(id=1319291687759888639, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=CN, orderNo=4, keyword=胰岛素抵抗), Keyword(id=1319291687835386112, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, language=CN, orderNo=5, keyword=组方要义)], refs=[Reference(id=1319291688099627267, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=易腾达, 李玉丽, 谭志强, 等. 经典名方开心散功能主治衍变与剂量的关联考证[J]. 中国实验方剂学杂志, 2021, 27(7): 24-33., articleTitle=null, refAbstract=null), Reference(id=1319291688166736132, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=FU H, XU Z, ZHANG X L, et al. Kaixinsan, a well-known Chinese herbal prescription, for Alzheimer's disease and depression: a preclinical systematic review[J]. Front Neurosci, 2020, 13: 1421., articleTitle=null, refAbstract=null), Reference(id=1319291688229650693, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=孙永康, 孙田烨, 李明远, 等. 开心散现代药理作用及作用机制研究[J]. 中国中医基础医学杂志, 2021, 27(4): 650-654., articleTitle=null, refAbstract=null), Reference(id=1319291688296759558, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=尚炳娴, 戴子琦, 吴倩文, 等. 经典名方开心散的处方与本草考证[J]. 西北药学杂志, 2022, 37(3): 12-19., articleTitle=null, refAbstract=null), Reference(id=1319291688363868423, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=AKYOL O, AKYOL S, CHOU M C, et al. Lipids and lipoproteins may play a role in the neuropathology of Alzheimer's disease[J]. Front Neurosci, 2023, 17: 1275932., articleTitle=null, refAbstract=null), Reference(id=1319291688430977288, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=CHOURPILIADIS C, ZENG Y, LOVIK A, et al. Metabolic profile and long-term risk of depression, anxiety, and stress-related disorders[J]. JAMA Netw Open, 2024, 7(4): e244525., articleTitle=null, refAbstract=null), Reference(id=1319291688514863369, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=易腾达, 李玉丽, 牛林强, 等. 经典名方开心散及类方的古代文献考证[J]. 中国实验方剂学杂志, 2021, 27(5): 8-15., articleTitle=null, refAbstract=null), Reference(id=1319291688590360842, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=张林, 曾凤. 《千金要方》开心散剂量的文献考证[J]. 北京中医药大学学报, 2020, 43(8): 641-644., articleTitle=null, refAbstract=null), Reference(id=1319291688657469707, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=殷俊梅, 王偲, 丁侃, 等. 经典名方开心散及其类方中医文献研究概述[J]. 中国医药导刊, 2023, 25(4): 416-419., articleTitle=null, refAbstract=null), Reference(id=1319291688737161484, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=殷俊梅, 王偲, 丁侃, 等. 古代经典名方开心散及其类方组方理论探析[J]. 中国医药导报, 2023, 20(33): 134-137., articleTitle=null, refAbstract=null), Reference(id=1319291688812658957, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=何贵平, 包祖晓, 陈宝君, 等. 开心散及其类方方证特征分析[J]. 中华中医药学刊, 2012, 30(3): 583-584., articleTitle=null, refAbstract=null), Reference(id=1319291688879767822, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=刘彦廷, 蔡忠明, 陈应柱. 《千金要方》“开心散”对血管性痴呆患者血浆ICAM-1影响研究[J]. 中医药临床杂志, 2015, 27(10): 1423-1425., articleTitle=null, refAbstract=null), Reference(id=1319291688942682383, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=包祖晓, 赵国平, 孙伟, 等. 开心散治疗轻、中度抑郁症临床观察[J]. 中华中医药学刊, 2011, 29(5): 987-988., articleTitle=null, refAbstract=null), Reference(id=1319291689005596944, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=YAO C, NIU L C, FU Y, et al. Cognition, motor symptoms, and glycolipid metabolism in Parkinson's disease with depressive symptoms[J]. J Neural Transm, 2022, 129(5-6): 563-573., articleTitle=null, refAbstract=null), Reference(id=1319291689064317201, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=YOON J H, SEO Y, JO Y S, et al. Brain lipidomics: From functional landscape to clinical significance[J]. Sci Adv, 2022, 8(37): eadc9317., articleTitle=null, refAbstract=null), Reference(id=1319291689139814674, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=LENG L G, YUAN Z Q, PAN R Y, et al. Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance[J]. Nat Metab, 2022, 4(10): 1287-1305., articleTitle=null, refAbstract=null), Reference(id=1319291689202729235, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHENG F F, YAN L, YANG Z C, et al. HbA(1c), diabetes and cognitive decline: the English Longitudinal Study of Ageing[J]. Diabetologia, 2018, 61(4): 839-848., articleTitle=null, refAbstract=null), Reference(id=1319291689295003924, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHANG J L, ZHENG X H, ZHAO Z Y. A systematic review and meta-analysis on the efficacy outcomes of selective serotonin reuptake inhibitors in depression in Alzheimer's disease[J]. BMC Neurol, 2023, 23(1): 210., articleTitle=null, refAbstract=null), Reference(id=1319291689383084309, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=郭庆军, 黄炜, 陈晓健, 等. 代谢综合征抑郁症共病机制研究进展[J]. 中国公共卫生, 2021, 37(1): 185-188., articleTitle=null, refAbstract=null), Reference(id=1319291689445998870, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=杨文山, 王一晨, 王元博, 等. 脑内脂质代谢在抑郁症发生发展中作用的研究进展[J]. 大连医科大学学报, 2022, 44(3): 239-243., articleTitle=null, refAbstract=null), Reference(id=1319291689513107735, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=李敏谦, 林育, 项磊, 等. 瘅浊与糖脂代谢病[J]. 世界中医药, 2019, 14(3): 652-655., articleTitle=null, refAbstract=null), Reference(id=1319291689584410904, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=晏樱豪, 张栎婧, 战丽彬. 基于“脾-肠”相关防治糖脂代谢性疾病[J]. 中华中医药学刊, 2024, 42(6): 91-94., articleTitle=null, refAbstract=null), Reference(id=1319291689651519769, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=沈桂祥. 浅谈脾胰同源[J]. 中医杂志, 2009, 50(12): 1141-1142., articleTitle=null, refAbstract=null), Reference(id=1319291689722822938, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=胡慧君, 刘莉, 隋艳波, 等. 浅析代谢综合征与中医“痰湿”理论的关系[J]. 中医药学报, 2020, 48(6): 30-32., articleTitle=null, refAbstract=null), Reference(id=1319291689794126107, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=钟敏, 唐小茗, 张新霞. 基于“阳化气, 阴成形”理论的糖脂代谢病中医药治疗探讨[J]. 亚太传统医药, 2021, 17(3): 204-206., articleTitle=null, refAbstract=null), Reference(id=1319291689852846364, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=王云龙, 黄健. 开心散治疗冠心病心绞痛痰浊瘀阻证46例效果分析[J]. 中西医结合心血管病电子杂志, 2017, 5(1): 86., articleTitle=null, refAbstract=null), Reference(id=1319291689919955229, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=龙运红, 李玲, 赵凌霄, 等. 基于脾散精藏神理论的开心散治疗糖尿病认知障碍的临床疗效观察[J]. 中医药学报, 2023, 51(2): 62-67., articleTitle=null, refAbstract=null), Reference(id=1319291689995452702, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=朱筱莲, 王小平. 开心散治疗冠心病合并抑郁症临床观察[J]. 医药前沿, 2012, 2(16): 132-133., articleTitle=null, refAbstract=null), Reference(id=1319291690058367263, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=null, journalName=null, refType=null, unstructuredReference=王太吉. 开心散治疗慢性心力衰竭合并抑郁症(心脾两虚证)的临床疗效观察[D]. 沈阳: 辽宁中医药大学, 2017., articleTitle=null, refAbstract=null), Reference(id=1319291690121281824, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=null, journalName=null, refType=null, unstructuredReference=张锦, 王登, 周珺, 等. 开心散、当归芍药散和圣约翰草对高脂加慢性应激大鼠行为学的影响及调节机制[J]. 中华中医药杂志, 2016, 31(10): 4230-4235., articleTitle=null, refAbstract=null), Reference(id=1319291690205167905, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[31], rfOrder=30, authorNames=null, journalName=null, refType=null, unstructuredReference=王登, 周珺, 张锦, 等. 开心散和当归芍药散对高脂饲料喂养的慢性应激大鼠糖脂代谢的影响及HPA轴相关机制[J]. 中药材, 2015, 38(9): 1919-1924., articleTitle=null, refAbstract=null), Reference(id=1319291690276471074, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[32], rfOrder=31, authorNames=null, journalName=null, refType=null, unstructuredReference=朱谋, 巩晓晨, 刘冬阳, 等. 人参皂苷Rb1对改善2型糖尿病大鼠糖脂代谢紊乱的作用[J]. 食品工业科技, 2022, 43(3): 367-373., articleTitle=null, refAbstract=null), Reference(id=1319291690343579939, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[33], rfOrder=32, authorNames=null, journalName=null, refType=null, unstructuredReference=LIU Q, ZHANG F G, ZHANG W S, et al. Ginsenoside Rg1 inhibits glucagon-induced hepatic gluconeogenesis through Akt-FoxO1 interaction[J]. Theranostics, 2017, 7(16): 4001-4012., articleTitle=null, refAbstract=null), Reference(id=1319291691962581284, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[34], rfOrder=33, authorNames=null, journalName=null, refType=null, unstructuredReference=高满军, 赵宝清, 莫启贵, 等. 茯苓的化学成分及其调节糖脂代谢的研究进展[J]. 湖北科技学院学报(医学版), 2023, 37(3): 272-276., articleTitle=null, refAbstract=null), Reference(id=1319291692046467365, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[35], rfOrder=34, authorNames=null, journalName=null, refType=null, unstructuredReference=张陶珍, 荣巍巍, 李清, 等. 远志的研究进展[J]. 中草药, 2016, 47(13): 2381-2389., articleTitle=null, refAbstract=null), Reference(id=1319291692105187622, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[36], rfOrder=35, authorNames=null, journalName=null, refType=null, unstructuredReference=石坚宏, 姬丽婷, 骆启晗, 等. 石菖蒲化学成分、药理作用及质量标志物预测分析研究进展[J]. 中成药, 2021, 43(5): 1286-1290., articleTitle=null, refAbstract=null), Reference(id=1319291692163907879, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[37], rfOrder=36, authorNames=null, journalName=null, refType=null, unstructuredReference=杨俊, 王健宇, 陈茏, 等. 肠道菌群对糖脂代谢影响的研究进展[J]. 微生物学通报, 2019, 46(5): 1146-1154., articleTitle=null, refAbstract=null), Reference(id=1319291692226822440, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[38], rfOrder=37, authorNames=null, journalName=null, refType=null, unstructuredReference=任巧盈, 王香懿, 李曜存, 等. 肠道菌群对代谢综合征影响的研究进展[J]. 山东医药, 2019, 59(14): 112-114., articleTitle=null, refAbstract=null), Reference(id=1319291692293931305, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[39], rfOrder=38, authorNames=null, journalName=null, refType=null, unstructuredReference=万蒙, 杨杨, 张同存. 肠道菌群影响糖代谢的因素及机制进展[J]. 中国实用内科杂志, 2020, 40(10): 865-869, 873., articleTitle=null, refAbstract=null), Reference(id=1319291692369428778, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[40], rfOrder=39, authorNames=null, journalName=null, refType=null, unstructuredReference=CAO C, LIU M Q, QU S C, et al. Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation-stress system[J]. J Ethnopharmacol, 2020, 261: 113055., articleTitle=null, refAbstract=null), Reference(id=1319291692444926251, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[41], rfOrder=40, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHU L, YE C, HU B F, et al. Regulation of gut microbiota and intestinal metabolites by Poria Cocos oligosaccharides improves glycolipid metabolism disturbance in high-fat diet-fed mice[J]. J Nutr Biochem, 2022, 107: 109019., articleTitle=null, refAbstract=null), Reference(id=1319291692503646508, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[42], rfOrder=41, authorNames=null, journalName=null, refType=null, unstructuredReference=SUN S S, WANG K, MA K, et al. An insoluble polysaccharide from the sclerotium of Poria Cocos improves hyperglycemia, hyperlipidemia and hepatic steatosis in ob/ob mice via modulation of gut microbiota[J]. Chin J Nat Med, 2019, 17(1): 3-14., articleTitle=null, refAbstract=null), Reference(id=1319291692562366765, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[43], rfOrder=42, authorNames=null, journalName=null, refType=null, unstructuredReference=SHI Y Y, CHEN J B, QU D, et al. Ginsenoside Rg (5) activates the LKB1/AMPK/mTOR signaling pathway and modifies the gut microbiota to alleviate nonalcoholic fatty liver disease induced by a high-fat diet[J]. Nutrients, 2024, 16(6): 842., articleTitle=null, refAbstract=null), Reference(id=1319291692625281326, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[44], rfOrder=43, authorNames=null, journalName=null, refType=null, unstructuredReference=CHEN Q J, JIA T R, WU X, et al. Polygalae radix oligosaccharide esters may relieve depressive-like behavior in rats with chronic unpredictable mild stress via modulation of gut microbiota[J]. Int J Mol Sci, 2023, 24(18): 13877., articleTitle=null, refAbstract=null), Reference(id=1319291692696584495, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[45], rfOrder=44, authorNames=null, journalName=null, refType=null, unstructuredReference=姚庆, 王浩安, 高文婷, 等. 脂肪细胞分泌的炎症因子及相关信号通路介导的肥胖和胰岛素抵抗[J]. 大连医科大学学报, 2022, 44(4): 341-345., articleTitle=null, refAbstract=null), Reference(id=1319291692772081968, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[46], rfOrder=45, authorNames=null, journalName=null, refType=null, unstructuredReference=LU X L, KONG X H, WU H, et al. UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders[J]. Cell Metab, 2023, 35(8): 1390-1405., articleTitle=null, refAbstract=null), Reference(id=1319291692834996529, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[47], rfOrder=46, authorNames=null, journalName=null, refType=null, unstructuredReference=李炎, 刘鹏飞, 刘学伟, 等. 开心散改善小鼠肥胖相关认知障碍的机制研究[J]. 中国中医基础医学杂志, 2024, 30(1): 46-52., articleTitle=null, refAbstract=null), Reference(id=1319291692914688307, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[48], rfOrder=47, authorNames=null, journalName=null, refType=null, unstructuredReference=NASERI K, SAADATI S, SADEGHI A, et al. The efficacy of ginseng (panax) on human prediabetes and type 2 diabetes mellitus: a systematic review and meta-analysis[J]. Nutrients, 2022, 14(12): 2401., articleTitle=null, refAbstract=null), Reference(id=1319291692990185780, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[49], rfOrder=48, authorNames=null, journalName=null, refType=null, unstructuredReference=LEE H C, CHENG W Y, HUANG BETG, et al. Anti-inflammatory and hypoglycemic efficacy of Poria Cocos and Dioscorea opposita in prediabetes mellitusrats[J]. RSCAdv, 2014, 4(98): 55649-55657., articleTitle=null, refAbstract=null), Reference(id=1319291693048906037, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[50], rfOrder=49, authorNames=null, journalName=null, refType=null, unstructuredReference=SUN S S, WANG K, SUN L, et al. Therapeutic manipulation of gut microbiota by polysaccharides of Wolfiporia Cocos reveals the contribution of the gut fungi-induced PGE (2) to alcoholic hepatic steatosis[J]. Gut Microbes, 2020, 12(1): 1830693., articleTitle=null, refAbstract=null), Reference(id=1319291693111820598, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[51], rfOrder=50, authorNames=null, journalName=null, refType=null, unstructuredReference=王梓宇, 张智慧, 吴鹏, 等. 基于肠道菌群和短链脂肪酸代谢探讨甘草制远志降低肠道炎症的作用机制[J]. 中草药, 2023, 54(14): 4556-4563., articleTitle=null, refAbstract=null), Reference(id=1319291693178929463, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[52], rfOrder=51, authorNames=null, journalName=null, refType=null, unstructuredReference=周高超, 王华, 王祎丹, 等. 开心散对D-半乳糖致衰老小鼠非酶糖基化和自由基的抑制作用研究[J]. 时珍国医国药, 2008, 19(6): 1400-1401., articleTitle=null, refAbstract=null), Reference(id=1319291693254426936, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[53], rfOrder=52, authorNames=null, journalName=null, refType=null, unstructuredReference=张天艺. 开心散对抑郁症合并心肌缺血模型大鼠的保护作用研究[D]. 北京: 北京中医药大学, 2018., articleTitle=null, refAbstract=null), Reference(id=1319291693313147193, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[54], rfOrder=53, authorNames=null, journalName=null, refType=null, unstructuredReference=SHI H, ZHAO J M, LI Y W, et al. Ginsenosides Rg1 regulate lipid metabolism and temperature adaptation in Caenorhabditis elegans[J]. J Ginseng Res, 2023, 47(4): 524-533., articleTitle=null, refAbstract=null), Reference(id=1319291693380256058, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[55], rfOrder=54, authorNames=null, journalName=null, refType=null, unstructuredReference=JIN W, LI C R, YANG S H, et al. Hypolipidemic effect and molecular mechanism of ginsenosides: a review based on oxidative stress[J]. Front Pharmacol, 2023, 14: 1166898., articleTitle=null, refAbstract=null), Reference(id=1319291693447364923, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[56], rfOrder=55, authorNames=null, journalName=null, refType=null, unstructuredReference=李乔, 张博. 茯苓多糖对2型糖尿病大鼠丝裂原激活的蛋白激酶通路及胰岛素抵抗的影响[J]. 安徽医药, 2022, 26(12): 2379-2382., articleTitle=null, refAbstract=null), Reference(id=1319291693535445308, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[57], rfOrder=56, authorNames=null, journalName=null, refType=null, unstructuredReference=韩思婕, 潘翔, 朱芊芊, 等. 茯苓多糖调节2型糖尿病模型大鼠肝脏糖异生的机制研究[J]. 中国药房, 2022, 33(13): 1581-1587., articleTitle=null, refAbstract=null), Reference(id=1319291693594165565, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[58], rfOrder=57, authorNames=null, journalName=null, refType=null, unstructuredReference=KIM J H, SIM H A, JUNG D Y, et al. Poria cocus wolf extract ameliorates hepatic steatosis through regulation of lipid metabolism, inhibition of ER stress, and activation of autophagy via AMPK activation[J]. Int J Mol Sci, 2019, 20(19): 4801., articleTitle=null, refAbstract=null), Reference(id=1319291693665468734, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[59], rfOrder=58, authorNames=null, journalName=null, refType=null, unstructuredReference=李光植, 黄瑛, 王琳. 远志对D-半乳糖致衰小鼠红细胞中超氧化物歧化酶、肝组织谷胱甘肽过氧化物酶活性影响的实验研究[J]. 黑龙江医药科学, 2000, 23(1): 4-5., articleTitle=null, refAbstract=null), Reference(id=1319291693732577599, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[60], rfOrder=59, authorNames=null, journalName=null, refType=null, unstructuredReference=OU H C, CHOU F P, LIN T M, et al. Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells[J]. Food Chem Toxicol, 2006, 44(9): 1485-1495., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319291687944438017, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, awardId=2023YFC3503102, language=CN, fundingSource=国家重点研发计划“中医药现代化”重点专项(2023YFC3503102), fundOrder=null, country=null), Fund(id=1319291688007352578, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, awardId=2026AFC0831, language=CN, fundingSource=湖北省自然科学基金中医药创新发展联合基金项目(2026AFC0831), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1319291684152787158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, xref=null, ext=[AuthorCompanyExt(id=1319291684161175767, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China), AuthorCompanyExt(id=1319291684169564376, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291683414589651, companyId=1319291684152787158, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=湖北中医药大学基础医学院，湖北　武汉　430065)])], figs=null, attaches=null, journal=Journal(id=1255846881855815682, delFlag=0, nameCn=中华中医药学刊, nameEn=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1673-7717, eissn=null, cn=21-1546/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=v4T+dd+NLAnioIpGAbkcEQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Archives of Traditional Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1777346829146, updatedTime=1788949222391, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=v4T+dd+NLAnioIpGAbkcEQ==, picEn=RAy5vuC40hwJB+Y0pEARug==, jcr=null, cjcr=null, exts=[JournalExt(id=1304510846391050374, language=CN, name=中华中医药学刊, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222419, updatedTime=1788949222419, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304510846449770631, language=EN, name=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222433, updatedTime=1788949222433, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1255847919539208197, websiteList=[Website(id=1255847989868900719, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN, language=CN, createTime=1777347093312, createBy=18614031015, updateTime=1777347427646, updateBy=18614031015, name=中华中医药学刊-中文, tplId=1146099689490845704, title=中华中医药学刊, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849512594170105, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=articleTextType, value=kx, createTime=1777347456358, updateTime=1777347456358, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512564809974, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=banner, value=null, createTime=1777347456352, updateTime=1777347456352, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512631918844, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=grayFlag, value=0, createTime=1777347456367, updateTime=1777347456367, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512552227061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347456348, updateTime=1777347456348, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512657084670, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=minRunFlag, value=0, createTime=1777347456373, updateTime=1777347456373, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512589975800, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic, createTime=1777347456357, updateTime=1777347456357, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512648696061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=silenceFlag, value=0, createTime=1777347456371, updateTime=1777347456371, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512581587191, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1777347456355, updateTime=1777347456355, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512619335930, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeColor, value=null, createTime=1777347456364, updateTime=1777347456364, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512627724539, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeStyle, value=null, createTime=1777347456366, updateTime=1777347456366, creator=18614031015, updator=18614031015)]), Website(id=1255847989944398211, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN, language=EN, createTime=1777347093330, createBy=18614031015, updateTime=1777347417860, updateBy=18614031015, name=中华中医药学刊-英文, tplId=1146101810881728533, title=Chinese Archives of Traditional Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849538993119491, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=articleTextType, value=kx, createTime=1777347462652, updateTime=1777347462652, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538972147968, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=banner, value=null, createTime=1777347462647, updateTime=1777347462647, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539047645446, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=grayFlag, value=0, createTime=1777347462665, updateTime=1777347462665, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538930204927, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347462637, updateTime=1777347462637, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539064422664, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=minRunFlag, value=0, createTime=1777347462669, updateTime=1777347462669, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538988925186, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic, createTime=1777347462651, updateTime=1777347462651, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539060228359, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=silenceFlag, value=0, createTime=1777347462668, updateTime=1777347462668, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538980536577, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1777347462649, updateTime=1777347462649, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539001508100, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeColor, value=null, createTime=1777347462654, updateTime=1777347462654, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539039256837, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeStyle, value=null, createTime=1777347462663, updateTime=1777347462663, creator=18614031015, updator=18614031015)])], journalTitle=中华中医药学刊, weixinUrl=null, journalUrl=https://castjournals.cast.org.cn/zhzyyxk, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Archives of Traditional Chinese Medicine, journalPhotoCn=v4T+dd+NLAnioIpGAbkcEQ==, journalPhotoEn=RAy5vuC40hwJB+Y0pEARug==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2026.07.027, detailUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2026.07.027, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/PDF/10.13193/j.issn.1673-7717.2026.07.027, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/PDF/10.13193/j.issn.1673-7717.2026.07.027, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1783612800000, fullTextJson=null, articleText=null, reference=null)