Article(id=1319291760614949792, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.012, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473266986, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473266986, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473266986, creator=13701087609, updateTime=1792473266986, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=61, endPage=64, ext={EN=ArticleExt(id=1319291760824664993, articleId=1319291760614949792, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Study on Mechanism of Gegen Qinlian Decoction (葛根芩连汤)“Treating Skin from Intestine” in Intervention of Atopic Dermatitis Based on Gut Microbiome, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Atopic dermatitis (AD) is a common, recurrent immunoinflammatory disease in dermatology characterized by eczematous rash and intense itching. The theory of the “gut-skin axis” suggests a close physiological and pathological relationship between the skin and the gut microbiome. The disorder of the gut bacterial and its metabolic products have been directly and indirectly linked to AD, making the regulation of the gut microbiome a new means of clinical intervention for AD. The traditional Chinese medicine (TCM) theory of “a skin disease indicating an intestinal disease” has already demonstrated the physiological and pathological connection between the intestines and the skin. Subsequently, some scholars have proposed that “skin and intestine affect each other”, advocating the treatment of skin diseases from the perspective of the intestine, namely the AD treatment approach of “treating skin from intestine”. Gegen Qinlian Decoction (葛根芩连汤), a classic formula from the Treatise on Cold Pathogenic Diseases, has proven effect in the clinical treatment of AD and a clear modern pharmacological regulatory effect on the gut microbiome. The treatment of AD with Gegen Qinlian Decoction not only follows the principles of TCM classic formulas, but also expands its application based on objective evidence from modern medicine. This article mainly discussed the feasibility of treating AD with Gegen Qinlian Decoction by regulating the gut microbiome, focusing on the principle of “treating skin from intestine”.

, authors=Liancheng GUAN¹, Fan YANG¹, Yujia CHEN¹, Zexin ZHAO¹, Hongxia LI¹, Deping LUO¹, Ping PANG¹, Yunzhi CHEN², authorsList=Liancheng GUAN, Fan YANG, Yujia CHEN, Zexin ZHAO, Hongxia LI, Deping LUO, Ping PANG, Yunzhi CHEN, authorCompany=null, correspAuthors=Yunzhi CHEN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291761223123874, articleId=1319291760614949792, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=基于肠道微生态探讨葛根芩连汤“从肠治皮”干预特应性皮炎的机制, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

特应性皮炎（atopic dermatitis，AD）是皮肤科常见的以湿疹样皮疹和剧烈瘙痒为主要特征的反复性免疫炎性疾病。“肠-皮轴”理论提出皮肤与肠道微生态在生理和病理方面存在密切联系，肠道菌群及其代谢产物紊乱与AD存在直接和间接联系，调控肠道微生态是临床干预AD的新手段。中医学“皮病则肠病”等经典理论早已表明肠腑与皮部的功能存在生理病理联系，继而有学者提出“皮肠同病”，提倡从肠论治皮肤病，即“皮病治肠”的AD治疗思路。葛根芩连汤是《伤寒论》经典方，临床治疗AD疗效确切，且对肠道微生态存在明确的现代药理调控作用。葛根芩连汤治疗AD既符合中医经典方证理论原则，又是基于现代医学客观证据的拓展运用。主要围绕“从肠治皮”探讨葛根芩连汤通过调节肠道微生态治疗AD的可行性。

, authors=管连城¹, 杨凡¹, 陈雨佳¹, 赵泽鑫¹, 李红霞¹, 罗德苹¹, 庞平¹, 陈云志², authorsList=管连城, 杨凡, 陈雨佳, 赵泽鑫, 李红霞, 罗德苹, 庞平, 陈云志, authorCompany=null, correspAuthors=陈云志, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=vL54JnjLzIooIDx/mVIJCg==, magXml=5iJ6VFeFVg0Mp8P2qAk+bQ==, pdfUrl=null, pdf=H12ucFIC/nlWqYcHAI5uYA==, pdfFileSize=1770464, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=gLnVRFvizeHGUO/m4+4Wrg==, mapNumber=null, fund=null)}, authors=[Author(id=1319291761613194154, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291760614949792, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319291761697080236, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291760614949792, authorId=1319291761613194154, language=EN, stringName=Liancheng GUAN, firstName=Liancheng, middleName=null, lastName=GUAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang 550002, Guizhou, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319291761768383405, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1319291760614949792, authorId=1319291761613194154, language=CN, stringName=管连城, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.贵州中医药大学第二附属医院，贵州　贵阳　550002, bio={"content":"

管连城（1990-），男，浙江台州人，主治医师，博士，研究方向：中西医结合基础与临床。

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管连城（1990-），男，浙江台州人，主治医师，博士，研究方向：中西医结合基础与临床。

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