Article(id=1319291621250810535, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.07.005, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1792473233758, onlineDateStr=2026-10-20, pubDate=1783612800000, pubDateStr=2026-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792473233758, onlineIssueDateStr=2026-10-20, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792473233758, creator=13701087609, updateTime=1792473233758, updator=13701087609, issue=Issue{id=1319291472856338924, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='7', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1783612800000', pubDateStr='2026-07-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792473198379, creator='13701087609', updateTime=1792473406504, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1319292345858773669, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1319292345858773670, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1319291472856338924, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=26, endPage=30, ext={EN=ArticleExt(id=1319291621439554216, articleId=1319291621250810535, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Exploration on Pathogenesis Evolution and Therapeutic Approaches of Chronic Refractory Cough Based on Theory of “Qi Deficiency Inducing Retention and Stagnation”, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

Chronic cough is the most common complaint in respiratory clinics and community outpatient departments. Chronic refractory cough is often treated repeatedly due to the persistence and recurrence of cough symptoms, which has become a difficult problem to be solved urgently in clinical practice. This article explored the pathogenesis evolution and therapeutic approaches of chronic refractory cough based on the theory of “Qi deficiency inducing retention and stagnation”. It holds that “Qi deficiency” is the internal basis for the onset of chronic refractory cough. According to the characteristics of the development of the pathogenesis stage, it can be divided into the beginning of the disease-deficiency of primary Qi and lung Yin, the gradual progression of the disease-deficiency of spleen Yang and failure of regulation, and the severe stage of the disease-deficiency of kidney essence and damage to the lung and spleen. The “retention and stagnation” of pathogenic factors such as phlegm-dampness, blood stasis and latent wind is the key pathological factor in the onset of chronic refractory cough. The retention of various pathogenic factors, ascending to the lung, causes upward rebellion of lung Qi, aggravating cough and leading to prolonged illness. The therapeutic approach should be based on the fundamental principles of tonifying deficiency and dredging stagnation, and commonly used treatment methods include nourishing lung Yin, warming spleen Yang, tonifying kidney essence, expelling latent wind, eliminating coagulation stasis, and resolving phlegm and dampness, with the aim of providing a reference for precise treatment of chronic refractory cough in clinical practice.

, authors=Linlin WANG1, Yongming LIU1, Lijian PANG1, Xiaodong LYU2, authorsList=Linlin WANG, Yongming LIU, Lijian PANG, Xiaodong LYU, authorCompany=null, correspAuthors=Xiaodong LYU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1319291621770904233, articleId=1319291621250810535, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=难治性慢性咳嗽“虚气留滞”病机演变与治疗思路探微, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

慢性咳嗽是呼吸专科与社区门诊中最常见的主诉。难治性慢性咳嗽往往因咳嗽症状迁延不愈反复就诊,现已成为临床迫切需要解决的棘手难题。基于“虚气留滞”理论对难治性慢性咳嗽的病机演变与治疗思路进行探讨,认为“虚气”为难治性慢性咳嗽发病内在基础,根据病机阶段发展特点可分为发病之始—主气不足、肺阴亏损,病进之渐—脾阳不振、斡旋失令,病重之势—肾元失充、肺脾受挫;痰湿、瘀血、伏风等邪气“留滞”为难治性慢性咳嗽发病的病理关键,诸邪留滞,上干于肺,肺气上逆,加重咳嗽并致迁延不愈。治疗思路当以补虚通滞为基本原则,常用养肺阴、温脾阳、培肾元、祛伏风、消凝瘀、化痰湿等治疗方法,以期为指导临床难治性慢性咳嗽精准治疗提供参考。

, authors=王琳琳1, 刘勇明1, 庞立健1, 吕晓东2, authorsList=王琳琳, 刘勇明, 庞立健, 吕晓东, authorCompany=null, correspAuthors=吕晓东, authorNote=

王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

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吕晓东(1966-),女,辽宁沈阳人,教授,博士研究生导师,博士,研究方向:中医药治疗肺系疾病基础和临床。E-mail:。
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王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

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王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

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难治性慢性咳嗽“虚气留滞”病机演变与治疗思路探微
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王琳琳 1 , 刘勇明 1 , 庞立健 1 , 吕晓东 2
中华中医药学刊 | 国家项目点击 2026,44(7): 26-30
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中华中医药学刊 |国家项目点击 2026 , 44 (7) : 26 -30
难治性慢性咳嗽“虚气留滞”病机演变与治疗思路探微
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王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

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王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

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王琳琳1, 刘勇明1, 庞立健1, 吕晓东2
作者信息
  • 1.辽宁中医药大学附属医院,辽宁 沈阳 110032
  • 2.辽宁中医药大学,辽宁 沈阳 110847
通讯作者:
吕晓东(1966-),女,辽宁沈阳人,教授,博士研究生导师,博士,研究方向:中医药治疗肺系疾病基础和临床。E-mail:。
作者简介:

王琳琳(1982-),女,辽宁盘锦人,主任医师,硕士研究生导师,硕士,研究方向:中医药治疗肺系疾病基础和临床。

Exploration on Pathogenesis Evolution and Therapeutic Approaches of Chronic Refractory Cough Based on Theory of “Qi Deficiency Inducing Retention and Stagnation”
Linlin WANG1, Yongming LIU1, Lijian PANG1, Xiaodong LYU2
Affiliations
  • 1.Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, Liaoning, China
  • 2.Liaoning University of Traditional Chinese Medicine, Shenyang 110847, Liaoning, China
出版时间: 2026-07-10 doi: 10.13193/j.issn.1673-7717.2026.07.005
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慢性咳嗽是呼吸专科与社区门诊中最常见的主诉。难治性慢性咳嗽往往因咳嗽症状迁延不愈反复就诊,现已成为临床迫切需要解决的棘手难题。基于“虚气留滞”理论对难治性慢性咳嗽的病机演变与治疗思路进行探讨,认为“虚气”为难治性慢性咳嗽发病内在基础,根据病机阶段发展特点可分为发病之始—主气不足、肺阴亏损,病进之渐—脾阳不振、斡旋失令,病重之势—肾元失充、肺脾受挫;痰湿、瘀血、伏风等邪气“留滞”为难治性慢性咳嗽发病的病理关键,诸邪留滞,上干于肺,肺气上逆,加重咳嗽并致迁延不愈。治疗思路当以补虚通滞为基本原则,常用养肺阴、温脾阳、培肾元、祛伏风、消凝瘀、化痰湿等治疗方法,以期为指导临床难治性慢性咳嗽精准治疗提供参考。

难治性慢性咳嗽  /  虚气留滞  /  病机演变  /  补虚通滞  /  治疗思路

Chronic cough is the most common complaint in respiratory clinics and community outpatient departments. Chronic refractory cough is often treated repeatedly due to the persistence and recurrence of cough symptoms, which has become a difficult problem to be solved urgently in clinical practice. This article explored the pathogenesis evolution and therapeutic approaches of chronic refractory cough based on the theory of “Qi deficiency inducing retention and stagnation”. It holds that “Qi deficiency” is the internal basis for the onset of chronic refractory cough. According to the characteristics of the development of the pathogenesis stage, it can be divided into the beginning of the disease-deficiency of primary Qi and lung Yin, the gradual progression of the disease-deficiency of spleen Yang and failure of regulation, and the severe stage of the disease-deficiency of kidney essence and damage to the lung and spleen. The “retention and stagnation” of pathogenic factors such as phlegm-dampness, blood stasis and latent wind is the key pathological factor in the onset of chronic refractory cough. The retention of various pathogenic factors, ascending to the lung, causes upward rebellion of lung Qi, aggravating cough and leading to prolonged illness. The therapeutic approach should be based on the fundamental principles of tonifying deficiency and dredging stagnation, and commonly used treatment methods include nourishing lung Yin, warming spleen Yang, tonifying kidney essence, expelling latent wind, eliminating coagulation stasis, and resolving phlegm and dampness, with the aim of providing a reference for precise treatment of chronic refractory cough in clinical practice.

chronic refractory cough  /  deficiency Qi inducing retention and stagnation  /  pathogenesis evolution  /  tonifying deficiency and dredging stagnation  /  therapeutic approach
王琳琳, 刘勇明, 庞立健, 吕晓东. 难治性慢性咳嗽“虚气留滞”病机演变与治疗思路探微. 中华中医药学刊, 2026 , 44 (7) : 26 -30 . DOI: 10.13193/j.issn.1673-7717.2026.07.005
Linlin WANG, Yongming LIU, Lijian PANG, Xiaodong LYU. Exploration on Pathogenesis Evolution and Therapeutic Approaches of Chronic Refractory Cough Based on Theory of “Qi Deficiency Inducing Retention and Stagnation”[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (7) : 26 -30 . DOI: 10.13193/j.issn.1673-7717.2026.07.005
  • 国家中医药管理局高水平中医药重点学科建设项目(国中医药人教函〔2023〕85号)
  • 国家中医药管理局第七批全国老中医药专家学术经验继承项目(国中医药人教函〔2022〕76号)
  • 辽宁省中医药传承创新团队项目(LNZYYCXTD-CCCX-001)
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doi: 10.13193/j.issn.1673-7717.2026.07.005
  • 首发时间:2026-10-20
  • 出版时间:2026-07-10
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基金
国家中医药管理局高水平中医药重点学科建设项目(国中医药人教函〔2023〕85号)
国家中医药管理局第七批全国老中医药专家学术经验继承项目(国中医药人教函〔2022〕76号)
辽宁省中医药传承创新团队项目(LNZYYCXTD-CCCX-001)
作者信息
    1.辽宁中医药大学附属医院,辽宁 沈阳 110032
    2.辽宁中医药大学,辽宁 沈阳 110847

通讯作者:

吕晓东(1966-),女,辽宁沈阳人,教授,博士研究生导师,博士,研究方向:中医药治疗肺系疾病基础和临床。E-mail:。
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https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2026.07.005
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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