Article(id=1317115164911063324, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.06.043, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954326130, onlineDateStr=2026-10-14, pubDate=1781020800000, pubDateStr=2026-06-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954326130, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954326130, creator=13701087609, updateTime=1791954326130, updator=13701087609, issue=Issue{id=1317114999827452826, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='6', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1781020800000', pubDateStr='2026-06-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954286772, creator='13701087609', updateTime=1791958677365, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133415753831385, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133415753831386, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317114999827452826, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=227, endPage=230, ext={EN=ArticleExt(id=1317115165112389917, articleId=1317115164911063324, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effect of Shugan Huayu Jieyu Decoction (疏肝化瘀解郁汤) Combined with Acupuncture on Post-Stroke Depression and Its Influence on Patients'Physical and Mental Health, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the effect of Shugan Huayu Jieyu Decoction (疏肝化瘀解郁汤) combined with acupuncture on post-stroke depression and its influence on patients'physical and mental health.
Methods A total of 119 patients with post-stroke depression admitted to the hospital from December 2020 to November 2023 were divided into groups by random number table method, and the patients were divided into western medicine group (59 cases) and traditional Chinese medicine group (60 cases). The patients in the western medicine group were treated with fluoxetine hydrochloride, and those in the traditional Chinese medicine group were treated with Shugan Huayu Jieyu Decoction combined with acupuncture therapy. The clinical efficacy and adverse reactions, traditional Chinese medicine symptom scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.) before and after treatment, Hamilton depression scale (HAMD) score and National Institute of Health stroke scale (NIHSS) score, the levels of norepinephrine (NE) and 5-hydroxytryptophan (5-HT), Pittsburgh sleep quality index (PSQI) and activities of daily living (ADL) scores of two groups were compared.
Results The total effective rate of traditional Chinese medicine group was 96.67%, which was higher than that of western medicine group (86.44%) (P<0.05). The adverse reaction rates of traditional Chinese medicine group and western medicine group were 3.33% and 3.39%, respectively, which were more tolerable by patients (P>0.05). Before treatment, traditional Chinese medicine syndrome scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.), HAMD score, NIHSS score, the levels of NE and 5-HT, PSQI score and ADL score were not significant in two groups (P>0.05). After treatment, traditional Chinese medicine syndrome scores (depression, loss of interest, irritability, slow thinking, insomnia, fatigue, etc.), HAMD scores, NIHSS scores, the levels of NE and 5-HT, PSQI scores and ADL scores were improved in two groups. After treatment, these indexes in traditional Chinese medicine group were all better than those in western medicine group (P<0.05).
Conclusion The combination of Shugan Huayu Jieyu Decoction and acupuncture in the treatment of post-stroke depression is significant, safe and reliable.
, authors=Jingjing LIU, Yuan ZHOU, Xiaojian ZHANG, Chunbo HAO, Ling LYU, Yanpeng ZHOU, Yingchang WANG, Huaibin MU, Xuelei JIAO, authorsList=Jingjing LIU, Yuan ZHOU, Xiaojian ZHANG, Chunbo HAO, Ling LYU, Yanpeng ZHOU, Yingchang WANG, Huaibin MU, Xuelei JIAO, authorCompany=null, correspAuthors=Xuelei JIAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115165636677918, articleId=1317115164911063324, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=疏肝化瘀解郁汤结合针刺治疗卒中后抑郁效果及对患者身心健康影响, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探讨疏肝化瘀解郁汤结合针刺治疗卒中后抑郁效果及对患者身心健康影响。
方法 纳入医院2020年12月—2023年11月收治的119例卒中后抑郁患者以随机数字表法进行分组，将患者分为西药组（59例）、中医组（60例），给予西药组患者盐酸氟西汀药物治疗，给予中医组患者疏肝化瘀解郁汤与针刺疗法结合治疗。数据比较：临床疗效及不良反应、治疗前后中医症候积分（神情抑郁、兴趣索然、心情烦躁、思维迟缓、失眠、神疲乏力等）变化及汉密尔顿抑郁量表（Hamilton Depression Scale，HAMD）与美国国立卫生院卒中量表（National Institute of Health stroke scale，NIHSS）评分变化、去甲肾上腺素（Norepinephrine，NE）与5-羟色胺（5-hydroxytryptophan，5-HT）水平变化、匹兹堡睡眠质量指数（Pittsburgh sleep quality index，PSQI）与日常生活活动能力量表（Activities of Daily Living，ADL）分值变化。
结果 中医组的总有效率为96.67%（51/59），比西药组患者总有效率（86.44%）更高，P<0.05；中医组患者与西药组不良反应率分别为3.33%、3.39%，均较多，患者可耐受，P>0.05；各组患者治疗前中医症候积分（神情抑郁、兴趣索然、心情烦躁、思维迟缓、失眠、神疲乏力等）、HAMD评分、NIHSS评分、NE及5-HT水平、PSQI与ADL评分相比，P>0.05；各组患者治疗后的中医症候积分（神情抑郁、兴趣索然、心情烦躁、思维迟缓、失眠、神疲乏力等）、HAMD评分、NIHSS评分、NE及5-HT水平、PSQI评分及ADL评分等指标均改善，中医组患者治疗后中医症候积分（神情抑郁、兴趣索然、心情烦躁、思维迟缓、失眠、神疲乏力等）、HAMD评分、NIHSS评分、NE及5-HT水平、PSQI评分及ADL评分等指标均优于西药组，P<0.05。
结论 疏肝化瘀解郁汤与针刺结合治疗卒中后抑郁效果显著，安全可靠。
, authors=刘晶晶, 周媛, 张小健, 郝春波, 吕玲, 周艳朋, 王迎昌, 穆怀斌, 焦雪蕾, authorsList=刘晶晶, 周媛, 张小健, 郝春波, 吕玲, 周艳朋, 王迎昌, 穆怀斌, 焦雪蕾, authorCompany=null, correspAuthors=焦雪蕾, authorNote=
刘晶晶（1980-），女，北京顺义人，副主任医师，硕士，研究方向：中医脑病。
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