中华中医药学刊

清热解瘀汤对甲状腺结节消融术后的临床应用

PDF下载

傅强 , 黄学阳 , 许锐 , 黄亚兰

中华中医药学刊 | 国家项目点击 2026,44(6): 191-194

收起

中华中医药学刊 |国家项目点击 2026 , 44 (6) : 191 -194

清热解瘀汤对甲状腺结节消融术后的临床应用

全屏

[Author(id=1319631210498863589, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319631210561778151, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210498863589, language=EN, stringName=Qiang FU, firstName=Qiang, middleName=null, lastName=FU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319631210628887016, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210498863589, language=CN, stringName=傅强, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=广东省中医院，广东广州 510006, bio={"content":"

傅强（1981-），男，广西桂林人，主治医生，硕士，研究方向：甲状腺疾病的中西医结合治疗及外科治疗。

"}, bioImg=null, bioContent=

傅强（1981-），男，广西桂林人，主治医生，硕士，研究方向：甲状腺疾病的中西医结合治疗及外科治疗。

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319631210410783201, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, xref=null, ext=[AuthorCompanyExt(id=1319631210419171810, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China), AuthorCompanyExt(id=1319631210427560419, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=广东省中医院，广东广州 510006)])]), Author(id=1319631210691801578, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319631210767299052, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210691801578, language=EN, stringName=Xueyang HUANG, firstName=Xueyang, middleName=null, lastName=HUANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319631210826019309, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210691801578, language=CN, stringName=黄学阳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=广东省中医院，广东广州 510006, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319631210410783201, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, xref=null, ext=[AuthorCompanyExt(id=1319631210419171810, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China), AuthorCompanyExt(id=1319631210427560419, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=广东省中医院，广东广州 510006)])]), Author(id=1319631210880545263, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319631210964431345, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210880545263, language=EN, stringName=Rui XU, firstName=Rui, middleName=null, lastName=XU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319631211039928818, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631210880545263, language=CN, stringName=许锐, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=广东省中医院，广东广州 510006, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319631210410783201, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, xref=null, ext=[AuthorCompanyExt(id=1319631210419171810, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China), AuthorCompanyExt(id=1319631210427560419, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=广东省中医院，广东广州 510006)])]), Author(id=1319631211111231988, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319631211182535158, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631211111231988, language=EN, stringName=Yalan HUANG, firstName=Yalan, middleName=null, lastName=HUANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319631211325141495, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, authorId=1319631211111231988, language=CN, stringName=黄亚兰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=广东省中医院，广东广州 510006, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319631210410783201, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, xref=null, ext=[AuthorCompanyExt(id=1319631210419171810, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China), AuthorCompanyExt(id=1319631210427560419, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115113174324070, companyId=1319631210410783201, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=广东省中医院，广东广州 510006)])])]

傅强, 黄学阳, 许锐, 黄亚兰

作者信息

广东省中医院，广东广州 510006

作者简介:

傅强（1981-），男，广西桂林人，主治医生，硕士，研究方向：甲状腺疾病的中西医结合治疗及外科治疗。

Clinical Application of Qingre Jieyu Decoction (清热解瘀汤) in Patients with Thyroid Nodules After Ablation

Qiang FU, Xueyang HUANG, Rui XU, Yalan HUANG

Affiliations

Guangdong Province Traditional Chinese Medical Hospital, Guangzhou 510006, Guangdong, China

出版时间: 2026-06-10 doi: 10.13193/j.issn.1673-7717.2026.06.035

文章导航

摘要

收起

目的

清热解瘀汤对甲状腺结节患者消融术后的治疗效果。

方法

纳入2021年6月—2023年6月广东省中医院甲状腺外科收治的100例行微波消融术治疗的甲状腺结节患者为研究对象，随机数字表法分为两组，对照组（50例）微波消融术后采用常规西药治疗，观察组（50例）微波消融术后采用清热解瘀汤治疗，对比两组治疗效果，症状评分、甲状腺结节最大径及体积变化、甲状腺功能指标等变化情况。

结果

治疗后观察组治疗总有效率为96.0%（48/50），远高于对照组（78.0%，39/50），且治疗后观察组疼痛、吞咽不适、肿胀热胀症状评分均低于对照组（P<0.05）。治疗后观察组结节最大径和结节体积小于对照组，且治疗后TSH、FT3、FT4水平优于对照组（P<0.05）。

结论

甲状腺结节患者微波消融术后应用清热解瘀汤治疗具有解热解毒，消痈散结的功效，能有效改善患者术后吞咽不适、肿胀、疼痛等症状，促进甲状腺结节体积缩小，改善甲状腺功能，促进术后尽快恢复。

关键词

甲状腺结节 / 清热解瘀汤 / 微波消融术 / 甲状腺功能 / 治疗效果

Abstract

收起

Objective

To investigate the therapeutic effect of Qingre Jieyu Decoction (清热解瘀汤) on the patients with thyroid nodules after ablation.

Methods

A hundred patients with thyroid nodules undergoing radiofrequency ablation treated in Guangdong Province Traditional Chinese Medical Hospital from June 2021 to June 2023 were included as the study objects, and were divided into two groups by the random number table method. Fifty patients in the control group were treated with conventional western medicine after radiofrequency ablation, and those in the observation group were treated with Qingre Jieyu Decoction after radiofrequency ablation. The therapeutic effects, symptom scores, maximum diameters and volumes of thyroid nodule, thyroid function indexes and so on of the two groups were compared.

Results

After treatment, the total effective rate of the observation group was 96.0%, which was much higher than that of the control group (78.0%), and the scores of pain, swallowing discomfort, swelling and thermal swelling in the observation group were lower than those in the control group (P<0.05). After treatment, the nodule maximum diameter and nodule volume in the observation group were smaller than those in the control group, and the levels of serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) after treatment were better than those in the control group (P<0.05).

Conclusion

The application of Qingre Jieyu Decoction after radiofrequency ablation for the patients with thyroid nodules can relieve heat and toxin, eliminate abscess and desiccation, effectively improve swallowing discomfort, swelling, pain and other symptoms of the patients after surgery, promote the reduction of thyroid nodules, improve the thyroid function and promote postoperative recovery as soon as possible.

Key words

thyroid nodules / Qingre Jieyu Decoction (清热解瘀汤) / radiofrequency / thyroid function / therapeutic effect

引用本文

傅强, 黄学阳, 许锐, 黄亚兰. 清热解瘀汤对甲状腺结节消融术后的临床应用. 中华中医药学刊, 2026 , 44 (6) : 191 -194 . DOI: 10.13193/j.issn.1673-7717.2026.06.035

Qiang FU, Xueyang HUANG, Rui XU, Yalan HUANG. Clinical Application of Qingre Jieyu Decoction (清热解瘀汤) in Patients with Thyroid Nodules After Ablation[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (6) : 191 -194 . DOI: 10.13193/j.issn.1673-7717.2026.06.035

基金

收起

吴阶平医学基金会项目(2022KT1010)

参考文献

收起

文献

收起

参考文献引证文献

排序方式：

［1］

汪晓露，赵勇，左新河，等．左新河运用中医药治疗甲状腺结节热消融术后经验［J］．现代中西医结合杂志，2022，31（20）：2841-2844.

［2］

刘德森，王钢，陈静，等．助微消瘿方在良性甲状腺结节微波消融术后的应用［J］．中国中医药科技，2023，30（4）：726-728.

［3］

中华医学会内分泌学分会，中华医学会外科学分会甲状腺及代谢外科学组，中国抗癌协会头颈肿瘤专业委员会，等．甲状腺结节和分化型甲状腺癌诊治指南（第二版）［J］．国际内分泌代谢杂志，2023，43（2）：149-194.

［4］

周仲瑛．中医内科学［M］．北京：中国中医药出版社，2004.

［5］

阙慈嫺，姜欣，陈瑞鸥，等．从“火毒”辨治甲状腺结节热消融术后声音嘶哑［J］．中医杂志，2023，64（2）：193-197.

［6］

CAI W J，LIU S S，YU X L，et al. Is partial ablation appropriate for benign thyroid nodules a retrospective study with long-term follow-up after microwave ablation［J］. Int J Hyperthermia，2021，38（1）：923-930.

［7］

YAN L，ZHANG M B，XIE F，et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules in patients with previous thyroid lobectomy［J］. BMC Med Imaging，2021，21（1）：47.

［8］

LANG B H，WU A L H. High intensity focused ultrasound（HIFU）ablation of benign thyroid nodules-a systematic review［J］. J Ther Ultrasound，2017，5：11.

［9］

张亚静．疏肝消瘿方治疗甲状腺结节微波消融术后临床观察［D］．天津：天津中医药大学，2017.

［10］

CERIT M N，YÜCEL C，CERIT E T，et al. Comparison of the efficiency of radiofrequency and microwave ablation methods in the treatment of benign thyroid nodules［J］. Acad Radiol，2023，30（10）：2172-2180.

［11］

刘颖洁，王小平，张宇，等．消瘿方凝胶治疗消融术后甲状腺结节疗效研究［J］．陕西中医，2019，40（9）：1241-1243.

［12］

刘桂梅，崔立平，孟秀峰，等．某高校教职工健康体检彩色多普勒超声诊断的主要疾病和筛查后经临床确诊的癌症结果与年龄关系分析［J］．影像研究与医学应用，2022，6（19）：179-181，184.

［13］

冯慧静，姜德友，田野，等．疏肝化痰消瘿汤治疗甲状腺结节的临床疗效及对中医证候积分变化的影响［J］．中药材，2022，45（3）：737-739.

［14］

孟然，薛志忠，鲁雪林，等．蒲公英的功效成分与药理作用研究进展［J］．江苏农业科学，2021，49（9）：36-43.

［15］

熊乐文，金莹，王彦予，等．金银花酚酸类化学成分、药理活性及体内代谢研究进展［J］．中成药，2022，44（3）：864-871.

［16］

李雅群，杨勇，王旭，等．金银花石油醚部位抗肺纤维化药效作用及其成分分析［J］．中药新药与临床药理，2021，32（9）：1268-1275.

［17］

陈晶晶，张文风，魏岩．黄芩防治疫病本草文献、药理学及临床研究概况［J］．长春中医药大学学报，2023，39（4）：371-374.

［18］

杨颖，田景振，陈智．炮制对黄芩药理作用与化学成分影响研究进展［J］．中华中医药学刊，2020，38（10）：230-235.

［19］

李茎，郑鹏，黎攀，等．广陈皮药理作用与临床应用研究进展［J］．吉林中医药，2022，42（9）：1092-1095.

［20］

张石凯，曹永兵．赤芍的药理作用研究进展［J］．药学实践杂志，2021，39（2）：97-101.

［21］

冯慧敏，李玥，罗旭东，等．当归化学成分和药理作用研究进展及质量标志物的预测分析［J］．中华中医药学刊，2022，40（4）：159-166.

［22］

陈金鹏，张克霞，刘毅，等．地黄化学成分和药理作用的研究进展［J］．中草药，2021，52（6）：1772-1784.

［23］

王小兰，段鹏飞，杨梦，等．生地黄多糖对环磷酰胺诱导的免疫抑制小鼠的免疫调节作用研究［J］．上海中医药大学学报，2021，35（1）：55-60，92.

［24］

张泽朝，叶学劲，朱闽，等．基于网络药理学探讨金钱草-土茯苓治疗慢性前列腺炎的作用机制［J］．中华中医药学刊，2021，39（4）：40-44.

［25］

李力恒，陈丽萍，胡晓阳，等．柴胡的化学成分及药理作用研究进展［J］．中医药学报，2023，51（2）：109-112.

［26］

王波，王丽，刘晓峰，等．中药甘草成分和药理作用及其现代临床应用的研究进展［J］．中国医药，2022，17（2）：316-320.

［27］

张矫雷．探究MSCT在肺部单发磨玻璃结节良恶性鉴别中的应用价值［J］．影像研究与医学应用，2023，7（10）：177-179.

［28］

许海兵，沈孝翠，吉玉刚．肺部磨玻璃样结节的影像学表现与其良恶性的相关性［J］．实用放射学杂志，2017，33（7）：1006-1009.

［29］

闫晓英．中药外敷联合汤药内服治疗桥本氏甲状腺炎合并结节（痰瘀互结证）的临床观察［J］．内蒙古中医药，2023，42（5）：95-96.

［30］

马淑芳．消瘿散结方治疗良性单纯性甲状腺结节阴虚痰火瘀结证的临床研究［D］．北京：北京中医药大学，2019.

［31］

冯建军，张学力，董惠洁，等．夏菇消瘿散治疗良性单纯性甲状腺结节临床观察［J］．光明中医，2019，34（2）：260-262.

［32］

袁艳倩．甲状腺结节的中医证候学研究［D］．北京：北京中医药大学，2017.

2026年第44卷第6期

PDF下载

引用本文

BibTeX

文章信息

doi: 10.13193/j.issn.1673-7717.2026.06.035

首发时间：2026-10-14
出版时间：2026-06-10

补充材料

相关文章

文章信息

作者

出版历史

基金

吴阶平医学基金会项目(2022KT1010)

作者信息

广东省中医院，广东广州 510006

参考文献

分享链接

https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2026.06.035

分享至

全文二维码

扫描看全文

引用本文

BibTeX

本文的引用情况

2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

关闭全屏

BibTeX
EndNote
RefWorks
TxT