Article(id=1317115079095599963, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.05.030, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954305670, onlineDateStr=2026-10-14, pubDate=1778342400000, pubDateStr=2026-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954305670, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954305670, creator=13701087609, updateTime=1791954305670, updator=13701087609, issue=Issue{id=1317115025307845060, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1778342400000', pubDateStr='2026-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954292847, creator='13701087609', updateTime=1791958713604, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133567340171275, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133567340171276, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=159, endPage=163, ext={EN=ArticleExt(id=1317115079338869596, articleId=1317115079095599963, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Research Progress on Prevention of Osteoporosis by Duzhong (Cortex Eucommiae) and Its Active Ingredients, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=

The incidence of osteoporosis continues to climb under the dual influence of the rising proportion of the elderly population and the unregulated use of hormone drugs in China. As a traditional Chinese medicinal herb, Duzhong (Cortex Eucommiae) is well known for its ability to nourish liver and kidney, and strengthen the muscles and bones. Clinicians have widely used Duzhong (Cortex Eucommiae) in the treatment of osteoporosis, mainly due to its key active ingredients such as saponins, phenols and sterols. These components can effectively regulate the growth and differentiation of osteoblasts, influence the process of bone metabolism, optimise the internal environment of bones, and play a key role in the prevention and treatment of osteoporosis by influencing the Wnt/β-catenin signalling pathway, the MAPK signaling pathway, the cytokine signaling pathway related to bone metabolism, and the estrogen signaling pathway. In this paper, it provided an overview of the latest research progress of Duzhong (Cortex Eucommiae) and its active ingredients in the prevention and treatment of osteoporosis, aiming to provide new research directions for Chinese medicine in the prevention and treatment of this disease.

, authors=Liang PEI¹, Jirong ZHAO^{1, 2}, Licun ZHANG¹, Wenyuan FENG¹, Wen CHEN³, Wentong YANG¹, Weinong LI², authorsList=Liang PEI, Jirong ZHAO, Licun ZHANG, Wenyuan FENG, Wen CHEN, Wentong YANG, Weinong LI, authorCompany=null, correspAuthors=Jirong ZHAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115079686996829, articleId=1317115079095599963, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=杜仲及其有效成分防治骨质疏松的研究进展, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=

在我国的老年人口比例逐年升高和激素类药物不规范使用的双重影响下，骨质疏松症的发病率持续攀升。作为一味传统的中医药材，杜仲以其滋补肝肾、增强筋骨的功效而著称。临床医生在骨质疏松症的治疗中广泛运用杜仲，这主要得益于其含有的皂苷、酚类和甾酮等多种关键活性成分。这些成分能够有效调控骨细胞的生长与分化、影响骨代谢过程、优化骨骼内部环境，并通过影响Wnt/β-catenin信号途径、MAPK信号途径、与骨代谢相关的细胞因子信号途径以及雌激素信号途径等机制，发挥出防治骨质疏松的关键作用。对杜仲及其活性成分在骨质疏松症防治方面的最新研究进展进行概述，旨在为中医药在防治该病症方面提供新的研究方向。

, authors=裴亮¹, 赵继荣^{1, 2}, 张立存¹, 冯文渊¹, 陈文³, 杨文通¹, 李玮农², authorsList=裴亮, 赵继荣, 张立存, 冯文渊, 陈文, 杨文通, 李玮农, authorCompany=null, correspAuthors=赵继荣, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=hLF62XdAImGzcC3el+jUdg==, magXml=2lZ3XcY7StILxTOmGHQEFQ==, pdfUrl=null, pdf=E6JFtjODEaXEMS0cCTOpCw==, pdfFileSize=1695182, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=4yqiYi8GJhE4BIsJ0T+gZg==, mapNumber=null, fund=null)}, authors=[Author(id=1319630486264197507, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630486360666501, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, authorId=1319630486264197507, language=EN, stringName=Liang PEI, firstName=Liang, middleName=null, lastName=PEI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1. Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630486549410182, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, authorId=1319630486264197507, language=CN, stringName=裴亮, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1．甘肃中医药大学，甘肃 兰州 730000, bio={"content":"

裴亮（1997-），男，甘肃天水人，硕士在读，研究方向：中医药防治脊柱疾患的临床与基础。

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裴亮（1997-），男，甘肃天水人，硕士在读，研究方向：中医药防治脊柱疾患的临床与基础。

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Trends in postmenopausal osteoporosis treatment in France during the period 2007-2016: a nationwide claims database analysis［J］. Bone, 2022, 154: 116255., articleTitle=null, refAbstract=null), Reference(id=1319630492048142774, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［2］, rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=SOBH MM, ABDALBARY M, ELNAGAR S, et al. Secondary osteoporosis and metabolic bone diseases［J］. J Clin Med, 2022, 11 (9) : 2382., articleTitle=null, refAbstract=null), Reference(id=1319630492106863031, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［3］, rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=ROUX C, BRIOT K. The crisis of inadequate treatment in osteoporosis［J］. Lancet Rheumatol, 2020, 2 (2) : e110-e119., articleTitle=null, refAbstract=null), Reference(id=1319630492203332024, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［4］, rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=CASTELO-BRANCO C. Management of osteoporosis. an overview［J］. Drugs Aging, 1998, 12 (Suppl 1) : 25-32., articleTitle=null, refAbstract=null), Reference(id=1319630492454990265, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［5］, rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=CLYNES MA, HARVEY N C, CURTIS E M, et al. The epidemiology of osteoporosis［J］. Br Med Bull, 2020, 133 (1) : 105-117., articleTitle=null, refAbstract=null), Reference(id=1319630492543070650, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［6］, rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=HENNEY A E, RILEY D R, O’CONNOR B, et al. Denosumab, for osteoporosis, reduces the incidence of type 2 diabetes, risk of foot ulceration and all-cause mortality in adults, compared with bisphosphonates: an analysis of real-world, cohort data, with a systematic review and meta-analysis［J］. Diabetes Obes Metab, 2024, 26 (9) : 3673-3683., articleTitle=null, refAbstract=null), Reference(id=1319630492836671931, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［7］, rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=ANAM A K, INSOGNA K. Update on osteoporosis screening and management［J］. Med Clin North Am, 2021, 105 (6) : 1117-1134., articleTitle=null, refAbstract=null), Reference(id=1319630492920558012, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［8］, rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=SONG S S, GUO Y Y, YANG Y H, et al. Advances in pathogenesis and therapeutic strategies for osteoporosis［J］. Pharmacol Ther, 2022, 237: 108168., articleTitle=null, refAbstract=null), Reference(id=1319630493000249789, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［9］, rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=BOLAMPERTI S, VILLA I, RUBINACCI A. Bone remodeling: an operational process ensuring survival and bone mechanical competence［J］. Bone Res, 2022, 10 (1) : 48., articleTitle=null, refAbstract=null), Reference(id=1319630493247713726, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［10］, rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=TANAKA Y, NAKAYAMADA S, OKADA Y. Osteoblasts and osteoclasts in bone remodeling and inflammation［J］. Curr Drug Targets Inflamm Allergy, 2005, 4 (3) : 325-328., articleTitle=null, refAbstract=null), Reference(id=1319630494933823935, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［11］, rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=TANAKA Y, ADAMS D H, HUBSCHER S, et al. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1 beta［J］. Nature, 1993, 361 (6407) : 79-82., articleTitle=null, refAbstract=null), Reference(id=1319630495042875840, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［12］, rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=林大栋．扶阳之祖：大宋窦材与《扁鹊心书》［M］．北京：中国中医药出版社，2021, articleTitle=null, refAbstract=null), Reference(id=1319630495151927745, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［13］, rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=梁伟乔，钟诚，李宇明．骨质疏松症的中医病因病机认识与治疗进展［J］.中国骨质疏松杂志，2020，26（1）：135-139., articleTitle=null, refAbstract=null), Reference(id=1319630495344865730, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［14］, rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=梁威，林艳明，周敬凯，等．2020年版《中华人民共和国药典》（一部）皮类中药和叶类中药的来源信息及显微鉴定规律［J］．亚太传统医药，2024，20（9）：28-32., articleTitle=null, refAbstract=null), Reference(id=1319630495453917635, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［15］, rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=刘聪，郭非非，肖军平，等．杜仲不同部位化学成分及药理作用研究进展［J］.中国中药杂志，2020，45（3）：497-512., articleTitle=null, refAbstract=null), Reference(id=1319630495541998020, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［16］, rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHAO X, WANG Y J, NIE Z Y, et al. Eucommia ulmoides leaf extract alters gut microbiota composition, enhances short-chain fatty acids production, and ameliorates osteoporosis in the senescence-accelerated mouse P6 (SAMP6) model［J］. Food Sci Nutr, 2020, 8 (9) : 4897-4906., articleTitle=null, refAbstract=null), Reference(id=1319630495625884101, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［17］, rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=杜丹凤，丁艳霞，李钦．杜仲叶颗粒抗骨质疏松作用及其机制［J］．河南大学学报（医学版），2023，42（3）：177-181., articleTitle=null, refAbstract=null), Reference(id=1319630495692992966, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［18］, rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=罗兰兰，张宇静，任明诗，等．杜仲汤对去卵巢大鼠骨质疏松症的影响及机制研究［J］.中药新药与临床药理，2024，35（4）：461-468., articleTitle=null, refAbstract=null), Reference(id=1319630495835599303, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［19］, rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=张风帅，王广亮，符朝程，等．张氏杜仲补骨汤治疗肝肾亏虚型原发性骨质疏松症临床观察［J］．辽宁中医药大学学报，2023，25（11）：37-40., articleTitle=null, refAbstract=null), Reference(id=1319630495915291080, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［20］, rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=史凡凡．杜仲腰痛丸含药血清对MC3T3-E1细胞增殖、分化的影响［D］．兰州：甘肃中医药大学，2023., articleTitle=null, refAbstract=null), Reference(id=1319630495994982857, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［21］, rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=朱换平，赵继荣，石敏，等．杜仲腰痛丸治疗老年骨质疏松性腰背痛患者的临床观察［J］.中药药理与临床，2021，37（6）：153-156., articleTitle=null, refAbstract=null), Reference(id=1319630496066286026, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［22］, rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=李晶，王波，王斌．全杜仲胶囊联合阿仑膦酸钠治疗老年骨质疏松症的临床研究［J］．现代药物与临床，2024，39（7）：1829-1833., articleTitle=null, refAbstract=null), Reference(id=1319630496133394891, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［23］, rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=张敏，梁凤妮，孙延文，等．杜仲化学成分、药理作用和临床应用研究进展［J］.中草药，2023，54（14）：4740-4761., articleTitle=null, refAbstract=null), Reference(id=1319630496204698060, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［24］, rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=曾梅，王朝晖，王志辉，等．基于HPLC指纹图谱及网络药理学的杜仲质量标志物预测分析［J］．天然产物研究与开发，2023，35（8）：1283-1296., articleTitle=null, refAbstract=null), Reference(id=1319630496276001229, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［25］, rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=BIAN D H, WU Y, SONG G D, et al. The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review［J］. Stem Cell Res Ther, 2022, 13 (1) : 24., articleTitle=null, refAbstract=null), Reference(id=1319630496338915790, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［26］, rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=KAWABATA T, OTSUKA T, FUJITA K, et al. (-) -Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts via attenuation of p38 MAPK activity［J］. Int J Mol Med, 2018, 42 (6) : 3149-3156., articleTitle=null, refAbstract=null), Reference(id=1319630496401830351, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［27］, rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=SINGH A K, SINGLA R K, PANDEY A K. Chlorogenic acid: a dietary phenolic acid with promising pharmacotherapeutic potential［J］. Curr Med Chem, 2023, 30 (34) : 3905-3926., articleTitle=null, refAbstract=null), Reference(id=1319630496477327824, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［28］, rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=SONG J Y, ZHANG Y F, ZHU Y F, et al. Structural characterization and anti-osteoporosis effects of polysaccharide purified from Eucommia ulmoides Oliver cortex based on its modulation on bone metabolism［J］. Carbohydr Polym, 2023, 306: 120601., articleTitle=null, refAbstract=null), Reference(id=1319630496561213905, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［29］, rfOrder=28, authorNames=null, journalName=null, refType=null, unstructuredReference=XIAO J C, ZHANG G Y, CHEN B H, et al. Quercetin protects against iron overload-induced osteoporosis through activating the Nrf2/HO-1 pathway［J］. Life Sci, 2023, 322: 121326., articleTitle=null, refAbstract=null), Reference(id=1319630496653488594, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［30］, rfOrder=29, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHOU Y H, XIE Q. Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway［J］. J Orthop Surg Res, 2021, 16 (1) : 660., articleTitle=null, refAbstract=null), Reference(id=1319630496737374675, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［31］, rfOrder=30, authorNames=null, journalName=null, refType=null, unstructuredReference=XIAO Y H, WEI R, YUAN Z, et al. Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis［J］. Am J Transl Res, 2019, 11 (10) : 6680-6690., articleTitle=null, refAbstract=null), Reference(id=1319630496838037972, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［32］, rfOrder=31, authorNames=null, journalName=null, refType=null, unstructuredReference=XIAO Y S, ZHANG S S, YE Y J, et al. Geniposide suppressed OX-LDL-induced osteoblast apoptosis by regulating the NRF2/NF-κB signaling pathway［J］. J Orthop Surg Res, 2023, 18 (1) : 641., articleTitle=null, refAbstract=null), Reference(id=1319630496921924053, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［33］, rfOrder=32, authorNames=null, journalName=null, refType=null, unstructuredReference=赵晶．杜仲叶提取物山柰酚对卵巢去势大鼠骨生成的影响及其与mTOR信号通路的关系研究［D］．南昌：南昌大学，2019., articleTitle=null, refAbstract=null), Reference(id=1319630496997421526, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［34］, rfOrder=33, authorNames=null, journalName=null, refType=null, unstructuredReference=贺自克，王上增．杜仲水提物上调Nur77表达促进骨髓间充质干细胞增殖和成骨分化［J］.中国组织工程研究，2023，27（15）：2371-2378., articleTitle=null, refAbstract=null), Reference(id=1319630497077113303, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［35］, rfOrder=34, authorNames=null, journalName=null, refType=null, unstructuredReference=WANG T, FAN L M, FENG S, et al. Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis［J］. Sci Rep, 2022, 12 (1) : 7430., articleTitle=null, refAbstract=null), Reference(id=1319630497152610776, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［36］, rfOrder=35, authorNames=null, journalName=null, refType=null, unstructuredReference=FILIPOWSKA J, TOMASZEWSKI K A, NIEDŹWIEDZKIŁ, et al. The role of vasculature in bone development, regeneration and proper systemic functioning［J］. Angiogenesis, 2017, 20 (3) : 291-302., articleTitle=null, refAbstract=null), Reference(id=1319630497215525337, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［37］, rfOrder=36, authorNames=null, journalName=null, refType=null, unstructuredReference=SIMUNOVIC F, FINKENZELLER G. Vascularization strategies in bone tissue engineering［J］. Cells, 2021, 10 (7) : 1749., articleTitle=null, refAbstract=null), Reference(id=1319630497286828506, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［38］, rfOrder=37, authorNames=null, journalName=null, refType=null, unstructuredReference=ABDURAHMAN A, LI X L, LI J, et al. Loading-driven PI3K/Akt signaling and erythropoiesis enhanced angiogenesis and osteogenesis in a postmenopausal osteoporosis mouse model［J］. Bone, 2022, 157: 116346., articleTitle=null, refAbstract=null), Reference(id=1319630497345548763, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［39］, rfOrder=38, authorNames=null, journalName=null, refType=null, unstructuredReference=FU R, LV W C, XU Y, et al. Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis［J］. Nat Commun, 2020, 11 (1) : 460., articleTitle=null, refAbstract=null), Reference(id=1319630497462989276, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［40］, rfOrder=39, authorNames=null, journalName=null, refType=null, unstructuredReference=LI Z Y, LIU C, LIU X L, et al. Aucubin impeded preosteoclast fusion and enhanced CD31^hi EMCN^hi vessel angiogenesis in ovariectomized mice［J］. Stem Cells Int, 2022, 2022: 5226771., articleTitle=null, refAbstract=null), Reference(id=1319630497534292445, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［41］, rfOrder=40, authorNames=null, journalName=null, refType=null, unstructuredReference=COLLINS F L, RIOS-ARCE N D, SCHEPPER J D, et al. The potential of probiotics as a therapy for osteoporosis［J］. Microbiol Spectr, 2017, 5 (4) : 4-5, 20., articleTitle=null, refAbstract=null), Reference(id=1319630497597207006, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［42］, rfOrder=41, authorNames=null, journalName=null, refType=null, unstructuredReference=COLLINS F L, STONE MD, TURTON J, et al. Oestrogen-deficiency induces bone loss by modulating CD14⁺ monocyte and CD4⁺ T cell DR3 expression and serum TL1 A levels［J］. BMC Musculoskelet Disord, 2019, 20 (1) : 326., articleTitle=null, refAbstract=null), Reference(id=1319630499266539999, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［43］, rfOrder=42, authorNames=null, journalName=null, refType=null, unstructuredReference=田硕，白明，苗明三．杜仲叶总黄酮对围绝经期大鼠模型的影响［J］.中华中医药杂志，2018，33（12）：5386-5391., articleTitle=null, refAbstract=null), Reference(id=1319630499333648864, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［44］, rfOrder=43, authorNames=null, journalName=null, refType=null, unstructuredReference=范宗林，黄健，刘思雪，等．基于CiteSpace的杜仲防治骨质疏松症研究可视化分析［J］．山东中医药大学学报，2024，48（4）：440-445., articleTitle=null, refAbstract=null), Reference(id=1319630499413340641, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［45］, rfOrder=44, authorNames=null, journalName=null, refType=null, unstructuredReference=PROCACCINI C, ROCCA C L, CARBONE F, et al. Leptin as immune mediator: Interaction between neuroendocrine and immune system［J］. Dev Comp Immunol, 2017, 66: 120-129., articleTitle=null, refAbstract=null), Reference(id=1319630499484643810, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［46］, rfOrder=45, authorNames=null, journalName=null, refType=null, unstructuredReference=DECKX N, LEE W P, BERNEMAN Z N, et al. Neuroendocrine immunoregulation in multiple sclerosis［J］. Clin Dev Immunol, 2013, 2013: 705232., articleTitle=null, refAbstract=null), Reference(id=1319630499568529891, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［47］, rfOrder=46, authorNames=null, journalName=null, refType=null, unstructuredReference=CAPLAN A, FETT N, ROSENBACH M, et al. Prevention and management of glucocorticoid-induced side effects: a comprehensive review: Gastrointestinal and endocrinologic side effects［J］. J Am Acad Dermatol, 2017, 76 (1) : 11-16., articleTitle=null, refAbstract=null), Reference(id=1319630499631444452, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［48］, rfOrder=47, authorNames=null, journalName=null, refType=null, unstructuredReference=DEN UYL D, BULTINK I E M, LEMS W F. Advances in glucocorticoid-induced osteoporosis［J］. Curr Rheumatol Rep, 2011, 13 (3) : 233-240., articleTitle=null, refAbstract=null), Reference(id=1319630499698553317, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［49］, rfOrder=48, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHANG R, LIU Z G, LI C, et al. Du-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in rats［J］. Bone, 2009, 45 (3) : 553-559., articleTitle=null, refAbstract=null), Reference(id=1319630499795022310, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［50］, rfOrder=49, authorNames=null, journalName=null, refType=null, unstructuredReference=WANG C Y, TANG L, HE J W, et al. Ethnobotany, phytochemistry and pharmacological properties of Eucommia ulmoides: a review［J］. Am J Chin Med, 2019, 47 (2) : 259-300., articleTitle=null, refAbstract=null), Reference(id=1319630499870519783, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115079095599963, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=［51］, rfOrder=50, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHAO Y, TAN D C, PENG B, et al. Neuroendocrine-immune regulatory network of Eucommia ulmoides oliver［J］. 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