Article(id=1317115089963037377, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.05.013, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954308261, onlineDateStr=2026-10-14, pubDate=1778342400000, pubDateStr=2026-05-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954308261, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954308261, creator=13701087609, updateTime=1791954308261, updator=13701087609, issue=Issue{id=1317115025307845060, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='5', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1778342400000', pubDateStr='2026-05-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954292847, creator='13701087609', updateTime=1791958713604, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133567340171275, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133567340171276, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115025307845060, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=65, endPage=67, ext={EN=ArticleExt(id=1317115090189529794, articleId=1317115089963037377, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Curative Effect Observation of Acupuncture Combined with Chaihu Shugan Powder (柴胡疏肝散) and Five-tone Therapy in Patients with Breast Hyperplasia of Liver Depression and Qi Stagnation Type, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective To observe the effect of acupuncture combined with Chaihu Shugan Powder (柴胡疏肝散) and five-tone therapy in the patients with breast hyperplasia of liver depression and Qi stagnation type.
Methods Eighty patients with hyperplasia of mammary glands of liver depression and Qi stagnation type diagnosed and treated in the hospital from April 2021 to December 2023 were selected as the research objects. They were randomly divided into two groups. Forty patients in the control group were treated with Chaihu Shugan Powder and five-tone therapy. Forty patients in the observation group were treated with acupuncture on the basis of the control group. The treatment cycle was 2 months. The clinical efficacy, breast mass indexes (mass texture, mass range, mass size), sex hormone index［estradiol (E2), progesterone (P), prolactin (PRL) ］and adverse reactions were compared between the two groups.
Results The markedly effective rate of the observation group was 85.00% (34/40), which was significantly higher than 65.00% (26/40) of the control group (P<0.05) . After treatment, the corresponding scores of tumor grade, tumor range and tumor size in the two groups were significantly decreased, and those in the observation group were lower than those in the control group［ (2.46±0.74) points, (3.11±0.89) points, (3.34±0.43) points vs (2.92±0.65) points, (6.07±1.58) points, (3.90±0.37) points］ (P<0.05) . After treatment, the levels of serum E2 and PRL decreased and the level of P increased in both groups. The levels of serum E2 and PRL in the observation group were lower than those in the control group, and the level of P was higher than that in the control group［ (64.82±6.31) pg/mL, (0.81±0.17) ng/mL, (16.78±2.49) ng/mL vs (69.53±7.06) pg/mL, (0.69±0.22) ng/mL, (19.05±3.14) ng/mL］ (P<0.05) . No serious adverse reactions occurred in the two groups.
Conclusion Acupuncture combined with Chaihu Shugan Powder and five-tone therapy has a significant effect on hyperplasia of mammary glands with liver depression and Qi stagnation. It can effectively improve the patients'ultrasound imaging and sex hormone indicators, and has a positive impact.
, authors=Lihong LIU, Bing YU, Weiwei ZHAO, Yunqian CHEN, Yingshun CUI, Beibei YANG, authorsList=Lihong LIU, Bing YU, Weiwei ZHAO, Yunqian CHEN, Yingshun CUI, Beibei YANG, authorCompany=null, correspAuthors=Beibei YANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115090659291843, articleId=1317115089963037377, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=针灸联合柴胡疏肝散及五音疗法治疗肝郁气滞型乳腺增生疗效观察, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的 研究针灸联合柴胡疏肝散及五音疗法治疗肝郁气滞型乳腺增生的效果。
方法 选取2021年4月—2023年12月医院诊治的肝郁气滞型乳腺增生患者80例作为研究对象，随机分为两组，对照组40例患者采用柴胡疏肝散及五音疗法治疗，观察组40例患者在对照组基础上增加针灸治疗，治疗周期2个月。比较两组患者临床疗效，乳腺肿块指标（肿块质地、肿块范围、肿块大小），性激素指标［雌二醇（estradiol，E2）、孕酮（progesterone，P）、泌乳素（prolactin，PRL）］及不良反应情况。
结果 观察组愈显率85.00%（34/40），显著高于对照组65.00%（26/40）（P<0.05），观察组总有效率97.50%（39/40），与对照组92.50%（37/40）相比差异无统计学意义（P>0.05）。治疗后两组患者肿块分级、肿块范围、肿块大小对应评分均显著降低，观察组低于对照组［（2.46±0.74）分、（3.11±0.89）分、（3.34±0.43）分vs（2.92±0.65）分、（6.07±1.58）分、（3.90±0.37）分］（P<0.05）。治疗后两组患者血清E2和PRL水平均下降、P水平上升，观察组血清E2和PRL水平低于对照组、P水平高于对照组［（64.82±6.31）pg/mL、（0.81±0.17）ng/mL、（16.78±2.49）ng/mL vs（69.53±7.06）pg/mL、（0.69±0.22）ng/mL、（19.05±3.14）ng/mL］（P<0.05）。两组患者无严重不良反应发生。
结论 针灸联合柴胡疏肝散及五音疗法对肝郁气滞型乳腺增生具有显著疗效，能够有效改善患者的超声影像学及性激素指标，具有积极影响。
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刘莉红（1987-），女，山东招远人，副主任医师，硕士，研究方向：超声医学。
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刘莉红（1987-），女，山东招远人，副主任医师，硕士，研究方向：超声医学。
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