Article(id=1317115240316256304, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.04.049, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954344108, onlineDateStr=2026-10-14, pubDate=1775750400000, pubDateStr=2026-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954344108, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954344108, creator=13701087609, updateTime=1791954344108, updator=13701087609, issue=Issue{id=1317115107243573307, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='4', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1775750400000', pubDateStr='2026-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954312382, creator='13701087609', updateTime=1791958738709, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133672680116252, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133672680116253, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=248, endPage=254, ext={EN=ArticleExt(id=1317115240538554417, articleId=1317115240316256304, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Lignans from Dangshen（Codonopsis pilosula）and Study of Their Anti-hypoxic Activities, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=

To study the structure of lignans from Dangshen（Codonopsis pilosula）and their anti-hypoxic activities. The ethanol extracts of Dangshen（Codonopsis pilosula）were separated and purified by D-101 column, silica gel column, ODS column and preparation HPLC. The structures were identified by physicochemical properties and various spectroscopic data. Highly differentiated PC12 cells with neuro-like properties were used to establish a chemical hypoxia model by CoCl₂ to screen the anti-hypoxic activity of the isolated compounds. The compound with the best anti-hypoxia activity was chosen for further investigation for the effects on lactate dehydrogenase（LDH）, reactive oxygen species（ROS）and mitochondrial membrane potential（MMP）under different concentrations. Ten compounds were classified as schisandrin A（1）, Gomisin N（2）, schisandrol A（3）, angylogyl gomisin Q（4）, angylogyl gomisin H（5）, benzoylgomisin Q（6）, gomisin A（7）, honokiol（8）, magnolol（9）and Codonopiloneolignanin A（10）. Compounds 1, 3-7 and 10 could increase the viability of hypoxic PC12 cells. The protection rates of compounds 1, 3, 4 and 6 were more than 20% at 10 μmol/L. Compound 3（schisandrol A）could reduce the leakage of LDH in PC12 cells of hypoxia induced by CoCl₂, reduce the production of ROS and slow down the decline of mitochondrial membranepotential caused by hypoxia. Ten lignans were isolated from Dangshen（Codonopsis pilosula）. Compounds 1-7 were dibenzo（a, c）cyclooctene lignans, compounds 8-9 were biphenyl lignans, compound 10 was new lignans with unique bridge ring carbon ring skeleton. Compounds 1-9 were isolated from the genus of Codonopsis for the first time. Compounds 1, 3-7 and 10 had a protective effect on neuronal cell damage caused by hypoxia. The protection rate of compounds 1, 3, 4 and 6 were more than 20% at 10 μmol/L. Compound 3（schisandrol A）might exert its protective activity by inhibiting the production of ROS in hypoxic cells and slowing down the degree of MMP depolarization caused by hypoxia.

, authors=Meng YAN¹, Yingjing WANG¹, Jiankuan LI¹, Jiangtao ZHOU¹, Xiaomin LI², Zhuoyang CHENG¹, Jianping GAO¹, authorsList=Meng YAN, Yingjing WANG, Jiankuan LI, Jiangtao ZHOU, Xiaomin LI, Zhuoyang CHENG, Jianping GAO, authorCompany=null, correspAuthors=Zhuoyang CHENG, Jianping GAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115240941207602, articleId=1317115240316256304, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=党参中木脂素类化学成分及其抗缺氧活性研究, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=

研究党参中木脂素类化学成分的结构及其抗缺氧活性。对党参醇提物通过系统溶剂萃取、D-101大孔吸附树脂、硅胶和ODS柱色谱，结合制备型高效液相色谱等进行单体化合物的分离纯化，利用化合物理化性质和多种波谱学方法进行结构鉴定。通过CoCl₂建立PC12细胞缺氧模型进行化合物抗缺氧活性体外筛选。检测高活性单体化合物在不同浓度条件下对缺氧细胞的乳酸脱氢酶（Lactate dehydrogenase，LDH）、活性氧（Reactive oxygen species，ROS）、线粒体膜电位（Mitochondrial membrane potential，MMP）的影响。最终从党参中分离纯化得到10个木脂素类化合物，分别为五味子醇甲（1），Gomisin N（2），五味子酯甲（3），当归酰基戈米辛Q（4），当归酰基戈米辛H（5），苯甲酰戈米辛Q（6），五味子醇乙（7），和厚朴酚（8），厚朴酚（9），Codonopiloneolignanin A（10），其中化合物1、3～7、10能增加缺氧PC12细胞的活力，化合物1、3、4和6在10 μmol/L浓度条件下保护率达到20%。化合物3（五味子酯甲）能够减少CoCl₂缺氧诱导的PC12细胞中LDH的泄漏量，增强细胞活力，减少缺氧细胞中ROS的生成、减缓缺氧导致的线粒体膜电位下降。从党参中分离得到10个木脂素类化合物中，1～7为联苯环辛烯型木脂素，8～9为联苯类木脂素，10是具有独特桥环碳环骨架的新木脂素化合物，其中1～9为首次从党参属中分离获得。化合物1、3～7、10对缺氧导致的神经细胞损伤有保护作用。化合物1、3、4和6在10 μmol/L浓度条件下保护率达到20%。化合物3（五味子酯甲）可能通过抑制缺氧细胞中ROS的生成、减缓缺氧导致的MMP去极化程度保护缺氧PC12细胞。

, authors=闫萌¹, 王盈静¹, 李建宽¹, 周江韬¹, 李晓敏², 程卓阳¹, 高建平¹, authorsList=闫萌, 王盈静, 李建宽, 周江韬, 李晓敏, 程卓阳, 高建平, authorCompany=null, correspAuthors=程卓阳, 高建平, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=V9NzsZjDag7zsssyaStqwA==, magXml=VS9XM1/qJgOO6rTSLM26zw==, pdfUrl=null, pdf=kaFQ8cAuHZZmEsU7luFxTQ==, pdfFileSize=4147884, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=ONBxujPieNNOWizeXzhxvA==, mapNumber=null, fund=null)}, authors=[Author(id=1319630659396686586, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630659480572668, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659396686586, language=EN, stringName=Meng YAN, firstName=Meng, middleName=null, lastName=YAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630659560264445, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659396686586, language=CN, stringName=闫萌, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio={"content":"

闫萌（1998-），女，甘肃酒泉人，硕士在读，研究方向：天然药物化学。

"}, bioImg=null, bioContent=

闫萌（1998-），女，甘肃酒泉人，硕士在读，研究方向：天然药物化学。

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])]), Author(id=1319630659631567615, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630659702870785, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659631567615, language=EN, stringName=Yingjing WANG, firstName=Yingjing, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630659790951170, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659631567615, language=CN, stringName=王盈静, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])]), Author(id=1319630659866448644, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630659946140422, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659866448644, language=EN, stringName=Jiankuan LI, firstName=Jiankuan, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630660021637895, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630659866448644, language=CN, stringName=李建宽, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])]), Author(id=1319630660105523977, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630660206187275, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660105523977, language=EN, stringName=Jiangtao ZHOU, firstName=Jiangtao, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630660298461964, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660105523977, language=CN, stringName=周江韬, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])]), Author(id=1319630660365570830, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1319630660449456912, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660365570830, language=EN, stringName=Xiaomin LI, firstName=Xiaomin, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2.Pingshun County Agricultural and Rural Bureau, Pingshun 047400, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630660524954385, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660365570830, language=CN, stringName=李晓敏, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=², address=^2.平顺县农业农村局，山西 平顺 047400, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659296023286, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=2., ext=[AuthorCompanyExt(id=1319630659308606199, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659296023286, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Pingshun County Agricultural and Rural Bureau, Pingshun 047400, Shanxi, China), AuthorCompanyExt(id=1319630659316994808, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659296023286, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.平顺县农业农村局，山西 平顺 047400)])]), Author(id=1319630660608840467, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=chengzy0328@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1319630660696920853, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660608840467, language=EN, stringName=Zhuoyang CHENG, firstName=Zhuoyang, middleName=null, lastName=CHENG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630660755641110, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660608840467, language=CN, stringName=程卓阳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])]), Author(id=1319630660818555672, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=jpgao123@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1319630660894053146, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660818555672, language=EN, stringName=Jianping GAO, firstName=Jianping, middleName=null, lastName=GAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1319630660956967707, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, authorId=1319630660818555672, language=CN, stringName=高建平, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=¹, address=^1.山西医科大学药学院，山西 晋中 030600, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)])])], keywords=[Keyword(id=1319630661103768348, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=EN, orderNo=1, keyword=Dangshen（Codonopsis pilosula）), Keyword(id=1319630661175071517, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=EN, orderNo=2, keyword=chemical components), Keyword(id=1319630661233791774, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=EN, orderNo=3, keyword=dibenzo（a，c）cyclooctene lignans), Keyword(id=1319630661326066463, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=EN, orderNo=4, keyword=hypoxia), Keyword(id=1319630661384786720, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=EN, orderNo=5, keyword=mitochondrial membrane potential), Keyword(id=1319630661435118369, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=CN, orderNo=1, keyword=党参), Keyword(id=1319630661502227234, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=CN, orderNo=2, keyword=化学成分), Keyword(id=1319630661552558883, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=CN, orderNo=3, keyword=联苯环辛烯型木脂素), Keyword(id=1319630661623862052, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=CN, orderNo=4, keyword=缺氧), Keyword(id=1319630661695165221, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, language=CN, orderNo=5, keyword=线粒体膜电位)], refs=[Reference(id=1319630661997155112, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=王维刚，阳志强，李晓琳，等.抗缺氧中药研究进展[J].天然产物研究与开发，2022，34（2）：344-357., articleTitle=null, refAbstract=null), Reference(id=1319630662060069673, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=COBB A B, LEVETT D Z H, MITCHELL K, et al. Physiological responses during ascent to high altitude and the incidence of acute mountain sickness[J]. Physiol Rep, 2021, 9（7）: e14809., articleTitle=null, refAbstract=null), Reference(id=1319630662135567146, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=LIU J C, GE Z, JIANG X, et al. A comprehensive review of natural products with anti-hypoxic activity[J]. Chin J Nat Med, 2023, 21（7）: 499-515., articleTitle=null, refAbstract=null), Reference(id=1319630662202676011, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=HE J Y, MA N, ZHU S, et al. The genus Codonopsis（Campanulaceae）: a review of phytochemistry, bioactivity and quality control[J]. J Nat Med, 2015, 69（1）: 1-21., articleTitle=null, refAbstract=null), Reference(id=1319630662273979180, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=国家药典委员会.中华人民共和国药典：一部[S].北京：中国医药科技出版社，2020：281., articleTitle=null, refAbstract=null), Reference(id=1319630662349476653, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=GAO S M, LIU J S, WANG M, et al. Traditional uses, phytochemistry, pharmacology and toxicology of Codonopsis: a review[J]. J Ethnopharmacol, 2018, 219: 50-70., articleTitle=null, refAbstract=null), Reference(id=1319630662429168430, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=ZHOU J T, WANG J J, LI D Y, et al. An inulin-type fructan CP-A from Codonopsis pilosula alleviates TNBS-induced ulcerative colitis based on serum-untargeted metabolomics[J]. Am J Physiol Gastrointest Liver Physiol, 2024, 326（3）: 216-227., articleTitle=null, refAbstract=null), Reference(id=1319630662508860207, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=LI J K, WANG T, ZHU Z C, et al. Structure features and anti-gastric ulcer effects of inulin-type fructan CP-A from the roots of Codonopsis pilosula（franch.）nannf[J]. Molecules, 2017, 22（12）: 2258., articleTitle=null, refAbstract=null), Reference(id=1319630662588551984, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=王妍.党参多糖CPC的结构解析及其免疫活性研究[D].晋中：山西医科大学，2022., articleTitle=null, refAbstract=null), Reference(id=1319630662659855153, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=null, journalName=null, refType=null, unstructuredReference=张俊卿.潞党参脂溶性化学成分及其抗炎活性研究[D].晋中：山西医科大学，2020., articleTitle=null, refAbstract=null), Reference(id=1319630662726964018, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=null, journalName=null, refType=null, unstructuredReference=谭文波，肖本见.富硒板党耐缺氧作用的实验研究[J].山东医药，2012，52（39）：58-59., articleTitle=null, refAbstract=null), Reference(id=1319630662802461491, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=null, journalName=null, refType=null, unstructuredReference=刘燎原.党参保健酒对小鼠抗疲劳及耐缺氧的作用研究[D].西安：陕西中医药大学，2015., articleTitle=null, refAbstract=null), Reference(id=1319630662890541876, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=null, journalName=null, refType=null, unstructuredReference=粟群芳，周紫婧.党参超微饮片对小鼠抗疲劳和耐缺氧作用的研究[J].中医药导报，2010，16（8）：95-96., articleTitle=null, refAbstract=null), Reference(id=1319630662957650741, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=null, journalName=null, refType=null, unstructuredReference=张东祥，张延坤，谢印芝.复方党参胶囊防治急性高原病的效果观察[J].解放军预防医学杂志，2005，23（4）：271-272., articleTitle=null, refAbstract=null), Reference(id=1319630663016370998, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=null, journalName=null, refType=null, unstructuredReference=王伟光，肖忠海，虞立霞，等.复方党参对低氧暴露小鼠认知功能的改善作用[J].解放军预防医学杂志，2016，34（3）：317-319，322., articleTitle=null, refAbstract=null), Reference(id=1319630663091868471, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=null, journalName=null, refType=null, unstructuredReference=刘飞，邹赢锌，焦勇，等.党参多糖对脑缺血再灌注损伤大鼠血清S100-β及NSE水平的影响[J].实验动物科学，2023，40（5）：53-59., articleTitle=null, refAbstract=null), Reference(id=1319630663171560248, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=null, journalName=null, refType=null, unstructuredReference=张壮，韦颖，刘楠，等.党参皂苷L1对抗缺氧缺糖再给氧诱导大鼠星形胶质细胞损伤的作用[J].中国临床康复，2006，10（27）：28-31., articleTitle=null, refAbstract=null), Reference(id=1319630663242863417, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=null, journalName=null, refType=null, unstructuredReference=KHAKSHOUR E, BAHREYNI-TOOSSI MT, ANVARI K, et al. Evaluation of the effects of simulated hypoxia by CoCl₂ on radioresistance and change of hypoxia-inducible factors in human glioblastoma U87 tumor cell line[J]. Mutat Res, 2024, 828: 111848., articleTitle=null, refAbstract=null), Reference(id=1319630663318360890, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=null, journalName=null, refType=null, unstructuredReference=PIAO L Z, LEE Y G, SHIN J C. Dibenzocyclooctene lignan compounds isolated from the fruits of Schisandra chinensis Baill[J]. Nat prod sci, 2005, （11）: 248-252., articleTitle=null, refAbstract=null), Reference(id=1319630663389664059, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=null, journalName=null, refType=null, unstructuredReference=TAN R, LI L N, FANG Q C. The stereostructure of wuweizisu B[J]. Planta Med, 1986, 52（1）: 49-51., articleTitle=null, refAbstract=null), Reference(id=1319630663469355836, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=null, journalName=null, refType=null, unstructuredReference=CHOI S K, LEE Y G, WANG R B, et al. Dibenzocyclooctadiene lignans from the fruits of Schisandra chinensis and their cytotoxicity on human cancer cell lines[J]. Appl Biol Chem, 2020, 63（1）: 39., articleTitle=null, refAbstract=null), Reference(id=1319630663553241917, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=null, journalName=null, refType=null, unstructuredReference=邸同莲，刘小清，吴楠，等.五味子中1个新的联苯环辛烯类木脂素[J].中草药，2023，54（12）：3759-3770., articleTitle=null, refAbstract=null), Reference(id=1319630663632933694, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=null, journalName=null, refType=null, unstructuredReference=IKEYA Y, MITSUHASHI H, SASAKI H, et al. Studies on the metabolism of gomisin A（TJN-101）.Ⅱ. Structure determination of biliary and urinary metabolites in rat[J]. Chem Pharm Bull（Tokyo）, 1990, 38（1）: 136-141., articleTitle=null, refAbstract=null), Reference(id=1319630663729402687, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=null, journalName=null, refType=null, unstructuredReference=邓世明，程永现，周俊，等.长缘厚朴中的新苯醌及新木脂素类化合物[J].云南植物研究，2001（1）：121-125., articleTitle=null, refAbstract=null), Reference(id=1319630663800705856, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=null, journalName=null, refType=null, unstructuredReference=JIANG Y P, GUO Q L, LIU Y F, et al. Codonopiloneolignanin A, a polycyclic neolignan with a new carbon skeleton from the roots of Codonopsis pilosula[J]. Chin Chem Lett, 2016, 27（1）: 55-58., articleTitle=null, refAbstract=null), Reference(id=1319630663867814721, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=null, journalName=null, refType=null, unstructuredReference=谢琦，程雪梅，胡芳弟，等.党参化学成分、药理作用及质量控制研究进展[J].上海中医药杂志，2020，54（8）：94-104., articleTitle=null, refAbstract=null), Reference(id=1319630663939117890, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=null, journalName=null, refType=null, unstructuredReference=孙政华，邵晶，郭玫.党参化学成分及药理作用研究进展[J].安徽农业科学，2015，43（33）：174-176., articleTitle=null, refAbstract=null), Reference(id=1319630664014615363, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=null, journalName=null, refType=null, unstructuredReference=苏维，王欣悦，付港，等.南五味子属植物的化学成分、药理作用及临床应用研究进展[J].中国中药杂志，2024，49（1）：26-38., articleTitle=null, refAbstract=null), Reference(id=1319630664094307140, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=null, journalName=null, refType=null, unstructuredReference=刘媛媛，黄仕其，李玉泽，等.五味子属植物木脂素类化学成分及其药理作用研究进展[J].中草药，2022，53（6）：1903-1918., articleTitle=null, refAbstract=null), Reference(id=1319630664161416005, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=null, journalName=null, refType=null, unstructuredReference=余凌虹，刘耕陶.五味子联苯环辛烯类木脂素成分的结构与药理活性关系和药物创新[J].化学进展，2009，21（1）：66-76., articleTitle=null, refAbstract=null), Reference(id=1319630664224330566, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[31], rfOrder=30, authorNames=null, journalName=null, refType=null, unstructuredReference=PRASHER P, FATIMA R, SHARMA M, et al. Honokiol and its analogues as anticancer compounds: current mechanistic insights and structure-activity relationship [J]. Chem Biol Interact, 2023, 386: 110747., articleTitle=null, refAbstract=null), Reference(id=1319630664278856519, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[32], rfOrder=31, authorNames=null, journalName=null, refType=null, unstructuredReference=LI X F, ZHANG J H, LIU G A, et al. High altitude hypoxia and oxidative stress: The new hope brought by free radical scavengers[J]. Life Sci, 2024, 336: 122319., articleTitle=null, refAbstract=null), Reference(id=1319630664345965384, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[33], rfOrder=32, authorNames=null, journalName=null, refType=null, unstructuredReference=TAZE C, DRAKOULI S, SAMIOTAKI M, et al. Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling[J]. Redox Biol, 2022, 58: 102545., articleTitle=null, refAbstract=null), Reference(id=1319630664417268553, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[34], rfOrder=33, authorNames=null, journalName=null, refType=null, unstructuredReference=蔡循，陈国强，陈竺，等.线粒体跨膜电位与细胞凋亡[J].生物化学与生物物理进展，2001，28（1）：4., articleTitle=null, refAbstract=null), Reference(id=1319630664484377418, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[35], rfOrder=34, authorNames=null, journalName=null, refType=null, unstructuredReference=LIU Y, LIU X B, WANG H, et al. Agrimonolide inhibits cancer progression and induces ferroptosis and apoptosis by targeting SCD1 in ovarian cancer cells[J]. Phytomedicine, 2022, 101: 154102., articleTitle=null, refAbstract=null), Reference(id=1319630664543097675, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[36], rfOrder=35, authorNames=null, journalName=null, refType=null, unstructuredReference=刘晓婷，王延让，张明.线粒体介导细胞凋亡的研究进展[J].环境与健康杂志，2013，30（2）：182-185., articleTitle=null, refAbstract=null)], funds=[Fund(id=1319630661846160166, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, awardId=202203021212380, language=CN, fundingSource=山西省科技厅青年科学研究项目(202203021212380), fundOrder=null, country=null), Fund(id=1319630661913269031, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, awardId=YDZX2023027, language=CN, fundingSource=山东省科技厅技术创新引导计划项目(YDZX2023027), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1319630659199554291, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=1., ext=[AuthorCompanyExt(id=1319630659207942900, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.School of Pharmacy of Shanxi Medical University, Jinzhong 030600, Shanxi, China), AuthorCompanyExt(id=1319630659220525813, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659199554291, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^1.山西医科大学药学院，山西 晋中 030600)]), AuthorCompany(id=1319630659296023286, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, xref=2., ext=[AuthorCompanyExt(id=1319630659308606199, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659296023286, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.Pingshun County Agricultural and Rural Bureau, Pingshun 047400, Shanxi, China), AuthorCompanyExt(id=1319630659316994808, tenantId=1146029695717560320, journalId=1255847919539208197, articleId=1317115240316256304, companyId=1319630659296023286, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=^2.平顺县农业农村局，山西 平顺 047400)])], figs=null, attaches=null, journal=Journal(id=1255846881855815682, delFlag=0, nameCn=中华中医药学刊, nameEn=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, issn=1673-7717, eissn=null, cn=21-1546/R, coden=null, periodic=0, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=v4T+dd+NLAnioIpGAbkcEQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Archives of Traditional Chinese Medicine, journalRemark=null, publicationField=null, createdTime=1777346829146, updatedTime=1788949222391, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=v4T+dd+NLAnioIpGAbkcEQ==, picEn=RAy5vuC40hwJB+Y0pEARug==, jcr=null, cjcr=null, exts=[JournalExt(id=1304510846391050374, language=CN, name=中华中医药学刊, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222419, updatedTime=1788949222419, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304510846449770631, language=EN, name=Chinese Archives of Traditional Chinese Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949222433, updatedTime=1788949222433, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=1, submissionEditorUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=3, submissionReviewUrl=https://zyhs.cbpt.cnki.net/index.aspx?t=2, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1255847919539208197, websiteList=[Website(id=1255847989868900719, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN, language=CN, createTime=1777347093312, createBy=18614031015, updateTime=1777347427646, updateBy=18614031015, name=中华中医药学刊-中文, tplId=1146099689490845704, title=中华中医药学刊, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849512594170105, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=articleTextType, value=kx, createTime=1777347456358, updateTime=1777347456358, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512564809974, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=banner, value=null, createTime=1777347456352, updateTime=1777347456352, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512631918844, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=grayFlag, value=0, createTime=1777347456367, updateTime=1777347456367, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512552227061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347456348, updateTime=1777347456348, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512657084670, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=minRunFlag, value=0, createTime=1777347456373, updateTime=1777347456373, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512589975800, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/file/pic, createTime=1777347456357, updateTime=1777347456357, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512648696061, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=silenceFlag, value=0, createTime=1777347456371, updateTime=1777347456371, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512581587191, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1777347456355, updateTime=1777347456355, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512619335930, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeColor, value=null, createTime=1777347456364, updateTime=1777347456364, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849512627724539, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989868900719, code=themeStyle, value=null, createTime=1777347456366, updateTime=1777347456366, creator=18614031015, updator=18614031015)]), Website(id=1255847989944398211, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1255847919539208197, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN, language=EN, createTime=1777347093330, createBy=18614031015, updateTime=1777347417860, updateBy=18614031015, name=中华中医药学刊-英文, tplId=1146101810881728533, title=Chinese Archives of Traditional Chinese Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1255849538993119491, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=articleTextType, value=kx, createTime=1777347462652, updateTime=1777347462652, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538972147968, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=banner, value=null, createTime=1777347462647, updateTime=1777347462647, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539047645446, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=grayFlag, value=0, createTime=1777347462665, updateTime=1777347462665, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538930204927, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=logo, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic?fileId=uitCA2DBwhJaQSiSV07uhw==, createTime=1777347462637, updateTime=1777347462637, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539064422664, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=minRunFlag, value=0, createTime=1777347462669, updateTime=1777347462669, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538988925186, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/file/pic, createTime=1777347462651, updateTime=1777347462651, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539060228359, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=silenceFlag, value=0, createTime=1777347462668, updateTime=1777347462668, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849538980536577, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1777347462649, updateTime=1777347462649, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539001508100, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeColor, value=null, createTime=1777347462654, updateTime=1777347462654, creator=18614031015, updator=18614031015), WebsiteProps(id=1255849539039256837, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1255847989944398211, code=themeStyle, value=null, createTime=1777347462663, updateTime=1777347462663, creator=18614031015, updator=18614031015)])], journalTitle=中华中医药学刊, weixinUrl=null, journalUrl=https://castjournals.cast.org.cn/zhzyyxk, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Archives of Traditional Chinese Medicine, journalPhotoCn=v4T+dd+NLAnioIpGAbkcEQ==, journalPhotoEn=RAy5vuC40hwJB+Y0pEARug==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/10.13193/j.issn.1673-7717.2026.04.049, detailUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/10.13193/j.issn.1673-7717.2026.04.049, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zhzyyxk/CN/PDF/10.13193/j.issn.1673-7717.2026.04.049, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zhzyyxk/EN/PDF/10.13193/j.issn.1673-7717.2026.04.049, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1775750400000, fullTextJson=null, articleText=null, reference=null)