Article(id=1317115286105469428, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.04.046, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954355025, onlineDateStr=2026-10-14, pubDate=1775750400000, pubDateStr=2026-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954355025, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954355025, creator=13701087609, updateTime=1791954355025, updator=13701087609, issue=Issue{id=1317115107243573307, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='4', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1775750400000', pubDateStr='2026-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954312382, creator='13701087609', updateTime=1791958738709, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133672680116252, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133672680116253, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=235, endPage=238, ext={EN=ArticleExt(id=1317115286298407413, articleId=1317115286105469428, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Clinical Observation of Xinyue Capsule（心悦胶囊）Combined with Radial Artery Approach for Coronary Intervention in Treatment of Coronary Heart Disease, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the clinical effect of Xinyue Capsule（心悦胶囊）combined with radial artery approach in the treatment of coronary artery disease.
Methods In this study, 200 patients with coronary heart disease admitted from January 2022 to January 2024 were divided into two groups by random number table method, and were evenly divided into a single intervention group and a combined treatment group, with 100 cases in each group. The patients in the single intervention group received coronary intervention by radial artery approach. Those in the combined treatment group were treated with Xinyue Capsule combined with radial artery approach for coronary intervention. During the treatment process, 3 patients in the simple intervention group fell off（97 patients remained）, 4 patients in the combined treatment group fell off（96 patients remained）, and the data of patients in each group was compared, including the treatment effect, TCM syndrome effect, hemorheological indexes such as D-dimer and fibrinogen before and after treatment and left ventricular posterior wall thickness（LVPWT）, left ventricular ejection fractions（LVEF）, left ventricular end diastolic diameter（LVEF）, left ventricular end diastolic diameter, changes of cardiac function indexes such as left ventricular end diastolic diameter（LVEDD）, changes of serum N terminal proB type natriuretic peptide（NT-proBNP）, visualanalogue scale（VAS）and EuroQol five dimensions questionnaire（EQ-5D）.
Results The total effective rate of the combined treatment group was significantly higher than that of the simple intervention group（P<0.05）. After treatment, hemorheology indexes（D-dimer and fibrinogen, etc.）, cardiac function indexes（LVPWT, LVEF, LVEDD）, NT-proBNP level, VAS and EQ-5D scores of the patients in both groups were significantly improved. The theses indexes of the combined treatment group were all better than those of the simple intervention group（P<0.05）. The complication rate of the combined treatment group was lower than that of intervention group（P<0.05）.
Conclusion The clinical effect of Xinyue Capsule combined with radial artery approach in the treatment of coronary artery intervention was relatively significant. After treatment, the patients＇ cardiac function was improved, the pain was relieved, the quality of life was improved, and the complications were reduced. The treatment is safe and reliable.
, authors=Houling ZHU, Zetao MA, Shan HUANG, Yang YANG, authorsList=Houling ZHU, Zetao MA, Shan HUANG, Yang YANG, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115286587814390, articleId=1317115286105469428, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=心悦胶囊结合桡动脉入路行冠状动脉介入治疗冠心病临床效果观察, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探讨心悦胶囊结合桡动脉入路行冠状动脉介入治疗冠心病的临床效果。
方法 研究纳入200例冠心病患者（2022年1月—2024年1月收治）以随机数字表法进行分组研究，平均分为单纯介入组、结合治疗组，各100例。单纯介入组采取桡动脉入路行冠状动脉介入治疗，结合治疗组采取心悦胶囊结合桡动脉入路行冠状动脉介入治疗，治疗过程中单纯介入组患者脱落3例，结合治疗组患者脱落4例，单纯介入组剩余97例，结合治疗组剩余96例，对比各组患者数据情况：治疗效果、中医证候疗效、治疗前后患者的D-二聚体及纤维蛋白原等血液流变学指标变化及左心室后壁厚度（left ventricular posterior wall thickness，LVPWT）、左心室射血分数（left ventricular ejection fractions，LVEF）、左室舒张末期内径（left ventricular end diastolic diameter，LVEDD）等心功能指标变化、血清N末端B型脑钠尿肽前体（N terminal pro B type natriuretic peptide，NT-proBNP）变化、患者疼痛评分（visual analogue scale，VAS）及五洲五维健康量表（EuroQol five dimensions questionnaire，EQ-5D）变化、并发症情况。
结果 结合治疗组患者治疗效果及中医证候疗效总有效率均显著高于单纯介入组（P<0.05）；治疗后各组患者血液流变学指标（D-二聚体及纤维蛋白原等）、心功能指标（LVPWT、LVEF、LVEDD）、NT-proBNP水平、VAS评分以及EQ-5D评分等指标均显著改善，而结合治疗组治疗后的血液流变学指标（D-二聚体及纤维蛋白原等）、心功能指标（LVPWT、LVEF、LVEDD）、NT-proBNP水平、VAS评分以及EQ-5D评分等指标均优于单纯介入组（P<0.05）；结合治疗组患者治疗并发症率比单纯介入组更低（P<0.05）。
结论 心悦胶囊结合桡动脉入路行冠状动脉介入治疗冠心病的临床效果较为显著，患者治疗后心功能好转，疼痛缓解，生活质量改善，且并发症减少，治疗安全可靠。
, authors=朱厚玲, 马泽涛, 黄珊, 杨洋, authorsList=朱厚玲, 马泽涛, 黄珊, 杨洋, authorCompany=null, correspAuthors=null, authorNote=
朱厚玲（1989-），女，海南东方人，主治医师，学士，研究方向：心血管疾病。
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朱厚玲（1989-），女，海南东方人，主治医师，学士，研究方向：心血管疾病。
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