Article(id=1317115276127220110, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.04.044, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954352646, onlineDateStr=2026-10-14, pubDate=1775750400000, pubDateStr=2026-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954352646, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954352646, creator=13701087609, updateTime=1791954352646, updator=13701087609, issue=Issue{id=1317115107243573307, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='4', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1775750400000', pubDateStr='2026-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954312382, creator='13701087609', updateTime=1791958738709, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133672680116252, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133672680116253, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=227, endPage=230, ext={EN=ArticleExt(id=1317115276328546703, articleId=1317115276127220110, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Effect of Compound Danshen Dripping Pills（复方丹参滴丸）Combined with Edaravone and Dexborneol Concentrated Solution on Serum Amyloid in Patients with Acute Cerebral Infarction, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the effect of Compound Danshen Dripping Pills（复方丹参滴丸）combined with edaravone and dexborneol concentrated solution on serum amyloid in the patients with acute cerebral infarction.
Methods One hundred and fifty inpatients with acute cerebral infarction in the Neurology Department of Tangshan Gongren Hospital from January 2022 to January 2024 were selected and grouped according to different treatment methods. All participants were given butylphthalide treatment. Based on this, the control group（74 cases）was given edaravone and dexborneol concentrated solution, whereas the observation group（76 cases）added Compound Danshen Dripping Pills combined with edaravone and dexborneol concentrated solution. The treatment in both groups lasted for 10-14 d. Then the neurological function recovery, serum amyloid, glycated serum protein, retinol binding protein 4, hemorheological parameters, clinical efficacy and adverse reactions were compared between two groups.
Results The observation group reported a lower score on National Institutes of Health Stroke Scale and modified Rankin Scale, and a higher Barthel index compared to the control group（P<0.05）. The levels of serum amyloid, glycated serum protein and retinol binding protein 4 decreased in the observation group compared to those in the control group（P<0.05）. The high and low shear whole blood viscosities, plasma viscosity and hematocrit were all smaller in the observation group than those in the control group（P<0.05）. The observation group denoted a higher overall efficacy rate than the control group（P<0.05）, while no statistical difference was found in adverse reaction rate between two groups（P>0.05）.
Conclusion The application of Compound Danshen Dripping Pills combined with edaravone and dexborneol concentrated solution in patients with acute cerebral infarction can effectively promote the recovery of neurological function, reduce the levels of serum amyloid, glycated serum protein and retinol binding protein 4, and ameliorate the blood viscosity.
, authors=Miao WANG, Qian ZHANG, Yue LYU, Yadan LU, Ying GAO, Jian LI, authorsList=Miao WANG, Qian ZHANG, Yue LYU, Yadan LU, Ying GAO, Jian LI, authorCompany=null, correspAuthors=Yue LYU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115276588593552, articleId=1317115276127220110, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=复方丹参滴丸联合依达拉奉右莰醇对急性脑梗死血清淀粉样蛋白的影响, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 探究复方丹参滴丸联合依达拉奉右莰醇对急性脑梗死患者血清淀粉样蛋白的影响。
方法 选取2022年1月—2024年1月唐山市工人医院神经内科住院的150例急性脑梗死患者。根据治疗方法不同进行分组，两组均给予丁苯酞治疗，其中对照组74例给予依达拉奉右莰醇治疗，观察组76例在对照组基础上结合复方丹参滴丸治疗，均治疗10～14 d。观察并比较两组神经功能恢复情况、血清淀粉样蛋白、糖化血清蛋白、视黄醇结合蛋白4、血液流变学指标、临床疗效及不良反应。
结果 观察组美国国立卫生研究院卒中量表和改良Rankin量表（Modified rankin scale，MRS）均明显低于对照组，Barthel指数明显高于对照组（P<0.05）。观察组血清淀粉样蛋白、糖化血清蛋白、视黄醇结合蛋白4水平明显低于对照组（P<0.05）。观察组高切全血黏度、低切全血黏度、血浆黏度、血细胞比容明显低于对照组（P<0.05）。观察组总有效率明显高于对照组（P<0.05）。两组发生率比较，差异无统计学意义（P>0.05）。
结论 复方丹参滴丸与依达拉奉右莰醇联合治疗效果明显，能加快神经功能恢复，降低血清淀粉样蛋白、糖化血清蛋白及视黄醇结合蛋白4水平，改善血液黏滞性。
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王淼（1990-），女，河北唐山人，主管药师，学士，研究方向：药物的临床应用。
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王淼（1990-），女，河北唐山人，主管药师，学士，研究方向：药物的临床应用。
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