Article(id=1317115342418203443, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.04.039, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791954368452, onlineDateStr=2026-10-14, pubDate=1775750400000, pubDateStr=2026-04-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791954368452, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791954368452, creator=13701087609, updateTime=1791954368452, updator=13701087609, issue=Issue{id=1317115107243573307, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='4', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1775750400000', pubDateStr='2026-04-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791954312382, creator='13701087609', updateTime=1791958738709, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317133672680116252, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317133672680116253, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317115107243573307, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=201, endPage=207, ext={EN=ArticleExt(id=1317115342598558516, articleId=1317115342418203443, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Variation of Sugars and Cyclic Enol Ether Terpene Glycosides Based on Different Forms of Fresh Xiandihuang（Radix et Rhizoma Dioscorea）, columnId=1256183365644968140, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Platform of Provincial Project, runingTitle=null, highlight=null, articleAbstract=
Objective To analyze the quality of different forms of Dihuang（Radix et Rhizoma Dioscorea）（juice decoction, fresh dried decoction, decoction）, to determine the contents of ingredients and establish the fingerprint map of different forms of Dihuang（Radix et Rhizoma Dioscorea）, so as to provide a basis for the clinical application of different forms.
Methods High Performance Liquid Chromatography（HPLC）measured the contents of three glycosides and five glycosides of Dihuang（Radix et Rhizoma Dioscorea）and established the HPLC fingerprint of different treatment forms.
Results The content order of three kinds of cyclic terpenoid components was fresh dried Dihuang（Radix et Rhizoma Dioscorea）decoction > Dihuang（Radix et Rhizoma Dioscorea） juice decoction > Dihuang（Radix et Rhizoma Dioscorea）decoction；the content order of 5 kinds of sugar was Dihuang（Radix et Rhizoma Dioscorea）juice decoction > fresh dried Dihuang（Radix et Rhizoma Dioscorea）decoction > Dihuang（Radix et Rhizoma Dioscorea）decoction. Twelve common peaks were calibrated in the fingerprint spectrum of different processing forms of Dihuang（Radix et Rhizoma Dioscorea）. Through the control comparison, six total peaks were identified, which were peach leaf coridin, reflavin D, reflavin A, motherthidin and hair flower glycoside. The similarity results showed that the similarity of different treatment forms of 30 batches ranged from 0.835 to 0.994, indicating a good similarity of the established fingerprint. Principal component analysis（PCA）and orthogonal least squares discriminant analysis（OPLS-DA）analysis showed differences in the quality of different treatment forms, and the main landmark components that differentiated different treatment forms were peaks 1, 2, 11, 12, 3（catalpol）, 10 and 5.
Conclusion In this study, the contents of different forms of Dihuang（Radix et Rhizoma Dioscorea）（decoction, fresh dried decoction and decoction）were determined, and the fingerprint of different forms of Dihuang（Radix et Rhizoma Dioscorea）was established, which provided the research basis and theoretical basis for the primary processing of fresh Dihuang（Radix et Rhizoma Dioscorea）and the clinical use of the juice.
, authors=Zhiyi FENG
1, 2, Wei ZHANG
3, Yunfa LI
1, 2, Haohan DUAN
1, 2, Yingying LI
1, 2, Caixia XIE
1, 2, Juan ZHANG
1, 2, Jingwei LEI
1, 2, authorsList=Zhiyi FENG, Wei ZHANG, Yunfa LI, Haohan DUAN, Yingying LI, Caixia XIE, Juan ZHANG, Jingwei LEI, authorCompany=null, correspAuthors=Juan ZHANG, Jingwei LEI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317115342841828149, articleId=1317115342418203443, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=基于鲜地黄不同入药形式探究糖类和环烯醚萜苷类成分含量变化, columnId=1256183369033965799, journalTitle=中华中医药学刊, columnName=省级项目平台, runingTitle=null, highlight=null, articleAbstract=
目的 对地黄不同入药形式（地黄汁煎液、鲜干地黄汤剂、生地黄汤剂）进行质量分析研究，测定成分含量并建立了地黄不同处理形式的指纹图谱，为地黄不同入药形式的临床应用提供依据。
方法 使用HPLC法测量地黄不同处理形式的3种环烯醚萜苷及5种糖类成分的含量并比较其含量差异，建立不同处理形式的HPLC指纹图谱。
结果 地黄样品中3种环烯醚萜苷类成分含量顺序为鲜干地黄汤剂>地黄汁煎液>生地黄汤剂，5种糖类成分含量总值顺序为地黄汁煎液>鲜干地黄汤剂>生地黄汤剂，地黄不同处理形式的指纹图谱共标定12个共有峰，通过对照品比对，指认6个共有峰，分别是梓醇、桃叶珊瑚苷、地黄苷D、地黄苷A、益母草苷、毛蕊花糖苷。相似度结果显示，30批地黄不同处理形式的相似度范围在0.835～0.994，表明建立的指纹图谱相似度良好。主成分分析（PCA）与正交偏最小二乘判别分析（OPLS-DA）显示不同处理形式地黄质量存在差异，并筛选出区分不同处理形式地黄产生差异的主要标志性成分为峰1、2、11、12、3（梓醇）、10、5。
结论 对地黄不同入药形式（生地黄汤剂、鲜干地黄汤剂和地黄汁煎液）的含量进行测定，建立了地黄不同处理形式的指纹图谱，为鲜地黄的产地初加工、地黄汁的临床使用提供研究基础和理论依据。
, authors=冯志毅
1, 2, 张威
3, 李运法
1, 2, 段浩瀚
1, 2, 李莹莹
1, 2, 谢彩侠
1, 2, 张娟
1, 2, 雷敬卫
1, 2, authorsList=冯志毅, 张威, 李运法, 段浩瀚, 李莹莹, 谢彩侠, 张娟, 雷敬卫, authorCompany=null, correspAuthors=张娟, 雷敬卫, authorNote=
冯志毅（1973-），男，河南林州人，副教授，博士，研究方向：中药性-药物质基础。
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1.School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
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1.河南中医药大学药学院，河南 郑州 450046
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1.School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, Henan, China
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