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Article(id=1317133184073057011, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, articleNumber=null, orderNo=null, doi=10.13193/j.issn.1673-7717.2026.01.032, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1791958622234, onlineDateStr=2026-10-14, pubDate=1767974400000, pubDateStr=2026-01-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1791958622234, onlineIssueDateStr=2026-10-14, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1791958622234, creator=13701087609, updateTime=1791958622234, updator=13701087609, issue=Issue{id=1317133098966433889, tenantId=1146029695717560320, journalId=1255847919539208197, year='2026', volume='44', issue='1', pageStart='1', pageEnd='258', issueExtLink='null', onlineDate='null', pubDate='1767974400000', pubDateStr='2026-01-10', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1791958601943, creator='13701087609', updateTime=1791958824557, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1317134032719171723, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1317134032719171724, tenantId=1146029695717560320, journalId=1255847919539208197, issueId=1317133098966433889, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=159, endPage=165, ext={EN=ArticleExt(id=1317133185813693175, articleId=1317133184073057011, tenantId=1146029695717560320, journalId=1255847919539208197, language=EN, title=Study on Quality Evaluation of Longgu（Os Draconis）, columnId=1256183361521967297, journalTitle=Chinese Archives of Traditional Chinese Medicine, columnName=Target on National Project, runingTitle=null, highlight=null, articleAbstract=
Objective

In order to explore the correlation between the traits，physical and chemical characteristics，phase composition and element content of Longgu（Os Draconis），a multi-dimensional scientific evaluation system of Longgu（Os Draconis）quality based on the theory of“differentiation of symptoms and quality”was established.

Methods

By consulting the records of the quality evaluation characteristics of Longgu（Os Draconis）in the past dynasties and modern literature，the key points of quality evaluation were sorted out and summarized. In addition，36 batches of Longgu（Os Draconis）samples were collected，and the preliminary identification was carried out by the character identification method. The phase composition was analyzed by XRD technology，and the physical and chemical indexes related to the character identification were detected，including moisture absorption rate，color difference and fluorescence. At the same time，ICP-OES technology was used to detect the contents of elements，and the correlation between the characteristics of Longgu（Os Draconis）traits and internal quality was studied by statistical analysis and metrology. The prediction model of“trait index-component content”was established.

Results

The texture，appearance characteristics，color，hygroscopicity and fluorescence of Longgu（Os Draconis）could be used as the indicators for the authenticity identification and quality of Longgu（Os Draconis）. The contents of Ca and P in Longgu（Os Draconis）were higher，followed by the contents of Mg，Fe and Al. Phase analysis showed that Longgu（Os Draconis）mainly contained fluorapatite and calcite. The color difference brightness was positively correlated with Ca and P，and the hygroscopicity was positively correlated with P and Sr. The ratio of Ca and P in the genuine product was greater than 2∶1，and the content of fluorapatite was more than 30.0%，with Ca≥30.00%，P≥7.00%，L value≥35.00 and moisture absorption rate≥1.00%.

Conclusion

The prediction model of“trait index-component content”established in this study was tested to be close to the actual value，and the model prediction effect was excellent. Based on the traditional theory of“differentiation of symptoms and nature”，the quality of Longgu（Os Draconis）can be accurately predicted，which provides a scientific basis for the improvement of the quality standard of Longgu（Os Draconis）.

, authors=Yunyun WANG1, Yuan SUN1, Xiaohui LIU2, Heyu LI3, Guohua ZHENG1, Juan LI1, authorsList=Yunyun WANG, Yuan SUN, Xiaohui LIU, Heyu LI, Guohua ZHENG, Juan LI, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1317133186124071672, articleId=1317133184073057011, tenantId=1146029695717560320, journalId=1255847919539208197, language=CN, title=龙骨质量评价研究, columnId=1256183362172142382, journalTitle=中华中医药学刊, columnName=国家项目点击, runingTitle=null, highlight=null, articleAbstract=
目的

为探索龙骨药材性状、理化特征、物相组成与元素含量之间的关联性，建立基于“辨状论质”理论的龙骨质量多维度科学评价体系。

方法

通过查阅历代本草及现代文献等对龙骨品质评价特征的记载，整理和归纳出其品质评价要点。此外，收集龙骨样品36批，通过性状鉴定方法进行初步鉴别，利用X射线衍射荧光（XRD）技术分析物相组成，并且检测性状鉴别相关的理化指标，包括吸湿率、色差值和荧光等。同时，采用电感耦合等离子体发射光谱仪（ICP-OES）技术检测元素含量，通过统计分析和计量学方法研究龙骨性状特征与内在质量的相关性，并建立“性状指标-成分含量”预测模型。

结果

龙骨药材质地、外观特征色泽、吸湿性和荧光等特征可作为龙骨真伪鉴别、质量优劣的指标。含量测定显示，龙骨Ca和P的含量较高，其次为Mg、Fe和Al。物相分析显示龙骨主要含氟磷灰石和方解石。色差值亮度（L）与Ca、P正相关，吸湿性与P、Sr含量正相关。龙骨合格品满足Ca和P的比例均大于2：1，氟磷灰石≥30.0%，且Ca≥30.00%，P≥7.00%，L值≥35.00，吸湿率≥1.00%。

结论

研究基于“辨状论质”建立龙骨元素和物相成分指标。同时建立“性状指标-成分含量”预测模型，经检验预测值与实际值相近，模型预测效果优良。基于传统“辨状论质”理论可较为准确地预测龙骨药材的质量，为龙骨药材质量标准的完善提供了科学基础。

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龙骨质量评价研究
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王云云 1 , 孙媛 1 , 刘小辉 2 , 李赫宇 3 , 郑国华 1 , 李娟 1
中华中医药学刊 | 国家项目点击 2026,44(1): 159-165
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中华中医药学刊 |国家项目点击 2026 , 44 (1) : 159 -165
龙骨质量评价研究
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王云云1, 孙媛1, 刘小辉2, 李赫宇3, 郑国华1, 李娟1
作者信息
  • 1.湖北中医药大学药学院，湖北武汉 430065
  • 2.孝感市公共检验检测中心，湖北孝感 432000
  • 3.天津益倍生物科技集团有限公司，天津 300201
Study on Quality Evaluation of Longgu（Os Draconis）
Yunyun WANG1, Yuan SUN1, Xiaohui LIU2, Heyu LI3, Guohua ZHENG1, Juan LI1
Affiliations
  • 1.College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China
  • 2.Xiaogan Public Inspection and Testing Center, Xiaogan 432000, Hubei, China
  • 3.Tianjin Yibei Biotechnology Group Co., Ltd., Tianjin 300201, China
出版时间: 2026-01-10 doi: 10.13193/j.issn.1673-7717.2026.01.032
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摘要
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目的

为探索龙骨药材性状、理化特征、物相组成与元素含量之间的关联性，建立基于“辨状论质”理论的龙骨质量多维度科学评价体系。

方法

通过查阅历代本草及现代文献等对龙骨品质评价特征的记载，整理和归纳出其品质评价要点。此外，收集龙骨样品36批，通过性状鉴定方法进行初步鉴别，利用X射线衍射荧光（XRD）技术分析物相组成，并且检测性状鉴别相关的理化指标，包括吸湿率、色差值和荧光等。同时，采用电感耦合等离子体发射光谱仪（ICP-OES）技术检测元素含量，通过统计分析和计量学方法研究龙骨性状特征与内在质量的相关性，并建立“性状指标-成分含量”预测模型。

结果

龙骨药材质地、外观特征色泽、吸湿性和荧光等特征可作为龙骨真伪鉴别、质量优劣的指标。含量测定显示，龙骨Ca和P的含量较高，其次为Mg、Fe和Al。物相分析显示龙骨主要含氟磷灰石和方解石。色差值亮度（L）与Ca、P正相关，吸湿性与P、Sr含量正相关。龙骨合格品满足Ca和P的比例均大于2：1，氟磷灰石≥30.0%，且Ca≥30.00%，P≥7.00%，L值≥35.00，吸湿率≥1.00%。

结论

研究基于“辨状论质”建立龙骨元素和物相成分指标。同时建立“性状指标-成分含量”预测模型，经检验预测值与实际值相近，模型预测效果优良。基于传统“辨状论质”理论可较为准确地预测龙骨药材的质量，为龙骨药材质量标准的完善提供了科学基础。

龙骨  /  理化鉴别  /  物相分析  /  元素  /  模式识别  /  质量评价
Objective

In order to explore the correlation between the traits，physical and chemical characteristics，phase composition and element content of Longgu（Os Draconis），a multi-dimensional scientific evaluation system of Longgu（Os Draconis）quality based on the theory of“differentiation of symptoms and quality”was established.

Methods

By consulting the records of the quality evaluation characteristics of Longgu（Os Draconis）in the past dynasties and modern literature，the key points of quality evaluation were sorted out and summarized. In addition，36 batches of Longgu（Os Draconis）samples were collected，and the preliminary identification was carried out by the character identification method. The phase composition was analyzed by XRD technology，and the physical and chemical indexes related to the character identification were detected，including moisture absorption rate，color difference and fluorescence. At the same time，ICP-OES technology was used to detect the contents of elements，and the correlation between the characteristics of Longgu（Os Draconis）traits and internal quality was studied by statistical analysis and metrology. The prediction model of“trait index-component content”was established.

Results

The texture，appearance characteristics，color，hygroscopicity and fluorescence of Longgu（Os Draconis）could be used as the indicators for the authenticity identification and quality of Longgu（Os Draconis）. The contents of Ca and P in Longgu（Os Draconis）were higher，followed by the contents of Mg，Fe and Al. Phase analysis showed that Longgu（Os Draconis）mainly contained fluorapatite and calcite. The color difference brightness was positively correlated with Ca and P，and the hygroscopicity was positively correlated with P and Sr. The ratio of Ca and P in the genuine product was greater than 2∶1，and the content of fluorapatite was more than 30.0%，with Ca≥30.00%，P≥7.00%，L value≥35.00 and moisture absorption rate≥1.00%.

Conclusion

The prediction model of“trait index-component content”established in this study was tested to be close to the actual value，and the model prediction effect was excellent. Based on the traditional theory of“differentiation of symptoms and nature”，the quality of Longgu（Os Draconis）can be accurately predicted，which provides a scientific basis for the improvement of the quality standard of Longgu（Os Draconis）.

Longgu（Os Draconis）  /  phase analysis  /  hysicochemical identification  /  elements  /  pattern recognition  /  quality evaluation
王云云, 孙媛, 刘小辉, 李赫宇, 郑国华, 李娟. 龙骨质量评价研究. 中华中医药学刊, 2026 , 44 (1) : 159 -165 . DOI: 10.13193/j.issn.1673-7717.2026.01.032
Yunyun WANG, Yuan SUN, Xiaohui LIU, Heyu LI, Guohua ZHENG, Juan LI. Study on Quality Evaluation of Longgu（Os Draconis）[J]. Chinese Archives of Traditional Chinese Medicine, 2026 , 44 (1) : 159 -165 . DOI: 10.13193/j.issn.1673-7717.2026.01.032

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doi: 10.13193/j.issn.1673-7717.2026.01.032
  • 首发时间：2026-10-14
  • 出版时间：2026-01-10
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    1.湖北中医药大学药学院，湖北武汉 430065
    2.孝感市公共检验检测中心，湖北孝感 432000
    3.天津益倍生物科技集团有限公司，天津 300201
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2种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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